test

Program Members

Co-Leaders

Pusztai, Lajos

Clinical Interests: breast cancer; cancer genetics.

  • Appt: (203) 200-2328
     

Members

Bale, Allen Everett

Research Interests: Molecular Mechanisms of Cancer; Predisposition and Developmental Defects; DNA Diagnostics; Birth Defects; Cancer; Fanconi; Genetics; Hedgehog; Multiple Endocrine Neoplasia; Patched; Skin Cancer; Tumor Suppressor

    Baserga, Susan J

    Research Interests: Ribosome biogenesis; RRNA processing; U3 RNP structure and function; RNA helicases; Polymerase I transcription and processing

      Blair, Lauren Paige

      Research Interests: cancer; epigenetics; RNA processing; histone demethylation; post-translational modification; mass spectrometry

      • Office: (203) 785-6496

      Bosenberg, Marcus W.

      Research Interests: Melanocytic neoplasms; Soft tissue tumors; Cutaneous lymphoma; Genodermatoses

      • Office: (203) 737-3484
      • Appt: (203) 785-4094

      Braddock, Demetrios

      Research Interests: Structural biology; Hematopathology; Genitourinary Pathology

      • Office: (203) 737-1278

      Carling, Tobias

      Research Interests: Improved outcomes in minimally invasive endocrine surgery; Molecular genetics of endocrine tumors of the thyroid, parathyroid, adrenal (hyperaldosteronism, hypercortisolism, adrenal cancer, pheochromocytoma) and endocrine pancreas; Familial endocrine tumor susceptibility syndromes; Regulation of calcium homeostasis

      • Appt: (203) 737-2036

      Carrasco, Nancy

      • Office: (203) 785-4117

      Cooley, Lynn

      Research Interests: Molecular Genetics of Drosophila Oogenesis; Actin Cytoskeleton Regulation; Drosophila; Oogenesis; Ring Canal; Ovarian Muscle Function

      • Office: (203) 432-3; 2
      • Lab: (203) 785-2675

      Costa, Jose

      Research Interests: Oncology; Carcinogenesis; Tumor development and progression; Advanced diagnostics; Molecular diagnostics; Diagnosed genetic alterations in tumors; Cancer risk detection by mutational load distribution analysis

      • Office: (203) 785-5803

      Garen, Alan

      Research Interests: Development; Genetics; Medical Sciences; Molecular Biology

        Giraldez, Antonio J.

        Research Interests: Developmental Biology; Non-coding RNAs, Post-transcriptional regulation; microRNAs; Gene regulatory networks; Systems Biology; Zebrafish

        • Office: (203) 785-5423

        Gunel, Murat

        Research Interests: Molecular genetics and biology of brain aneurysms and cavernous malformations; Molecular genetics of brain development

        • Office: (203) 737-2096
        • Appt: (203) 737-2096

        Halaban, Ruth

        Research Interests: Genes controlling differentiation, proliferation, malignant transformation of melanocytes; Growth factors and receptor kinases; Signal transduction; Epigenetic modification and gene expression; Markers for melanoma, Next-Generation sequencing, mutations

        • Office: (203) 785-4352

        Halene, Stephanie

        Research Interests: Hematopoiesis; Myeloid differentiation; Leukemia; Myelodysplasia

        • Appt: (203) 200-4363

        Hatzis, Christos

        Research Interests: Personalized medicine; Molecular diagnostics; Cancer heterogeneity; Next generation sequencing; Diagnostic study design

          Hofstatter, Erin Wysong

          • Appt: (203) 200-2328

          Hoh, Josephine

          Research Interests: Interactions among genes; Environmental exposures

          • Office: (203) 785-2738
          • Lab: (203) 737-6007

          Ivanova, Natalia B.

          Research Interests: Embryonic and somatic stem cells; Vertebrate development; Functional genomics; Systems biology

            Katz, Samuel G.

            • Office: (203) 785-2757

            Khan, Sajid A

            Research Interests: Cancer; metastasis; oligometastasis; microRNA; gene expression profiling; microsatellite instability; clinical outcomes; surgical resection; surgical palliation; liver metastasis; pancreas; gastric cancer; gastrointestinal stromal tumors (GIST); early onset colorectal cancer; sarcoma

            • Office: (203) 737-7915
            • Appt: (203) 337-8507

            Kidd, Kenneth Kay

            Research Interests: Complex Human Disorders; Neuropsychiatric Disorders; Human Population ; Genetics; Human Evolution

            • Office: (203) 785-2654
            • Lab: (203) 785-2653

            Kluger, Yuval

            Research Interests: Signal processing and dimensional reduction of genome-wide data; Local and non-local genomic pattern recognition; Identification of cancer subclones with proliferation and invasion potential in heterogeneous cancer biopsies

            • Office: (203) 737-6262

            Konigsberg, William H

            Research Interests: Blood Coagulation; DNA Replication; Genetics; Proteins and Macromolecules

              Krause, Diane S

              Research Interests: Bone Marrow Transplantation; Stem Cells; Cell and Molecular Hematology; Leukemia

              • Office: (203) 737-1678

              Kupfer, Gary

              Research Interests: Genomic instability; Development of cancer; Genetic syndrome Fanconi anemia (FA); Viral protein enhancement of cancer therapeutics

              • Office: (203) 785-4640
              • Appt: (203) 785-4640

              Lazova, Rossitza

              Research Interests: Spitz nevi; Spitzoid melanocytic neoplasms; Malignant melanoma; Melanocytic nevi on special anatomic sites

              • Office: (203) 785-4094
              • Appt: (203) 785-4094

              Leffell, David J.

              Research Interests: Molecular biology of basal cell carcinoma, squamous cell carcinoma; Wound healing; Skin cancer epidemiology

              • Appt: (203) 785-3466

              Lengyel, Peter

              Research Interests: p200 family proteins; mammalian differentiation; cell proliferation; interferons

                Li, Peining

                Research Interests: Cytogenetic and genomic analysis; Dissection of genetic mechanisms for growth regulation, mental development, and cancer progression

                • Office: (203) 785-6317
                • Appt: (203) 785-6317

                Lifton, Richard P

                Research Interests: Molecular genetics of common human diseases

                  Lin, Haifan

                  Research Interests: Stem cell RNA-mediated epigenetic programming, post-transcriptional regulation

                  • Office: (203) 785-6239
                  • Lab: (203) 785-6215

                  Llor, Xavier

                  Research Interests: Mismatch Repair Proficient Hereditary Non-Polyposis Colorectal Cancer; MSS-HNPCC: Lynch syndrome; Colorectal Cancer Disparities: Colorectal Cancer in African Americans

                  • Appt: (203) 200-5083

                  Lu, Jun

                  Research Interests: Non-coding RNAs in blood stem cell differentiation and malignancies; MicroRNA-mediated control of embryonic stem cell fates; MicroRNA mechanisms

                  • Office: (203) 737-3426

                  Mane, Shrikant M.

                  • Office: (203) 737-3104
                  • Lab: (203) 737-3058

                  Materin, Miguel A

                  Research Interests: Role of cytogenetics in ocular oncology for diagnosis and prognosis; Improving diagnostic and treatment methods for eye tumors

                  • Appt: (203) 200-3937

                  McGrath, James Michael

                  Research Interests: Developmental Genetics; Genetic Imprinting; Embryogenesis; Spermatogenesis

                  • Office: (203) 785-2686
                  • Appt: (203) 785-2660

                  Noonan, James

                  Research Interests: Human Evolution; Evolutionary Dynamics of Gene Regulation; Synthetic Biology; Applications of Ultra-High Throughput Sequencing Technologies; Comparative and Functional Genomics in Vertebrates

                    Pillai, Manoj M

                    • Office: (203) 737-6403
                    • Lab: (203) 737-6990

                    Prasad, Manju

                    Research Interests: Endocrine, Head & Neck Pathology; Genotype-phenotype correlation in tumors; Protein expression and biomarkers in tumor tissues, and their diagnostic & prognostic relevance

                    • Office: (203) 785-4862

                    Pusztai, Lajos

                    Research Interests: Breast cancer; Translational cancer research; Developing pharmacogenomic markers of response to breast cancer therapy and identifying methods to select the optimal treatment for each patient

                    • Appt: (203) 200-2328

                    Schwartz, Peter E

                    Research Interests: Ovarian Cancer; Uterine; Vaginal; Cervical and vulvar cancer; Screening for ovarian cancer

                    • Office: (203) 785-4014
                    • Appt: (203) 785-4014

                    Seli, Emre U

                    Research Interests: Translational regulation of gene expression during oocyte end early embryo development; Assessment of embryo viability in assisted reproductive technologies; Pathogenesis of endomentriosis.

                    • Office: (203) 785-7873
                    • Appt: (203) 785-4708

                    Shadel, Gerald S

                    Research Interests: Mitochondria; Mitochondrial Genetics and Biogenesis; Mitochondrial Dysfunction in Human Disease and Aging; Mechanisms of mtDNA Transcription and Mitochondrial Translation; Signaling Pathways that Sense and Control Mitochondrial Function; Cancer; Immune System Signaling

                    • Office: (203) 785-2475

                    Sklar, Jeffrey L.

                    Research Interests: Molecular biology of human disease, especially cancer; Molecular biologic methods of disease diagnosis; Cancer-related genes and their functions in neoplasia and normal cellular physiology; Chromosomal structure and chromosomal abnormalities in genetic and neoplastic disorders; Immunogenetics

                    • Office: (203) 785-6836

                    Strout, Matthew

                    Research Interests: Cancer genetics; Lymphomagenesis; Leukemogenesis; Immune diversification; Epigenetics; Tissue banking; Targeted therapy

                    • Office: (203) 785-7002
                    • Lab: (203) 737-6425
                    • Appt: (203) 200-4363

                    Taylor, Hugh S.

                    Research Interests: Endometriosis; Stem Cells; Embryo Implantation; Asherman's Syndrome; Menopause; Uterine Development; Endorcrine Disruption; Developmental Programming

                    • Office: (203) 785-4001
                    • Appt: (203) 785-4708

                    Udelsman, Robert

                    Research Interests: Minimally invasive surgery; Including techniques for minimizing the trauma of surgery; Endocrine surgery; Endocrine oncology

                    • Office: (203) 785-2697
                    • Appt: (203) 785-2697

                    Weissman, Sherman Morton

                    Research Interests: Globin and Histocompatibility Gene Structure and Function; Genome wide mapping of gene activity and chromosome structure in man; Transcription Factors; Lymphocyte and myeloid Transcription Networks; Stem Cells; Cell Senescence; Methods for Molecular Genetics

                    • Office: (203) 737-2281

                    Xiao, Andrew Zhuo

                    Research Interests: Chromatin biology; Histone variants; Modifications and chromatin remodeling complexes; Cellular reprogramming (iPS) and stem cell biology; Mammalian neural crest cell; Mammalian DNA damage response

                    • Office: (203) 737-3650
                    • Lab: (203) 785-5111

                    Xu, Mina LuQing

                    Research Interests: Peripheral T-cell lymphoma, NOS; Classical hodgkin lymphoma; EBV-related lymphoproliferative disorders; Hemophagocytic lymphohistiocytosis; Hematopoietic stem cell niche

                    • Office: (203) 737-6135

                    Xu, Tian

                    Research Interests: Genetic methodology; Cancer biology; Food and metabolism; Developmental mechanisms

                      Yan, Qin

                      Research Interests: Epigenetics; Gene regulation; Cancer biology; Stem cell biology

                      • Office: (203) 785-6672

                      Zhao, Hongyu

                      Research Interests: Statistical genomics; Computational biology; Genetic epidemiology; Genome wide association studies; Complex diseases; Risk prediction; High dimensional data; Dimension reduction; Network models; Graphical models; Bioinformatics; Next generation sequencing analysis; Cancer genomics; Epigenetics; Herbal medicine; Cicrobiome; Proteomics

                      • Office: (203) 785-3613