| Yale Faculty Participate in ASTRO Annual Meeting Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven will once again have wonderful presence at the annual American Society for Radiation Oncology meeting beginning this weekend. Congratulations to the following faculty members for their participation: Leadership Roles: Bryan Chang
Moderator for the Pancreatic Cancer Session
Peter Glazer
Chair of the ASTRO Research Committee; Panelist on the microRNAs in Cancer Session
Susan Higgins
ASTRO Faculty Member; Member of the Annual Scientific Program Committee and the Educational Committee; Reviewed for the Gynecologic Abstracts; Co-Moderator for the Enhancing Safety Culture in Radiation Oncology Session
Meena Moran
Chair of The ASTRO Breast Abstract Panel Committee
Joanne Weidhaas
Chair and Panelist for the microRNAs in Cancer Session
Lynn Wilson
Vice Chair of the ASTRO Scientific Program Committee; Moderator and Invited Speaker for the ARRO Career Seminar; Moderator for the Clinical Trials Session; Moderator for the Press Conference highlighting the top four research breakthroughs from the conference; and Participant in the Meet the Professor Session
James Yu
Moderator for the Outcomes and Health Service Research, Palliative Care, and Quality of Life Session
Presentations: Bryan Chang Poster Presentation - A Comparative Analysis Between 3D Non-coplanar Beam Technique (NCBT) versus Single-isocenter Multi-segment Conformal Arc (SiMs) Technique for Liver Stereotactic Body Radiotherapy (SBRT)
Roy Decker
Educational Session - Stereotactic Body Radiotherapy: Clinical and Biological Update Oral Presentation - Prognostic Value of p16 Expression in Laryngeal Cancer Patients Treated with RadiationPoster Presentation - Role of Excision Repair Cross Complementation 1 Expression as a Prognostic Marker for Response to Radiotherapy in Early Stage Laryngeal Cancer
Peter Glazer
Oral Presentation -Mechanism of Radiation Sensitization by Inhibitors Poly(ADP-ribose) Polymerase (PARP) Oral Presentation - Hypoxia and microRNAs in Cancer Biology
Cary Gross
Poster Presentation - Head and Neck Cancer (HNC) Patients Undergoing Intensity Modulated Radiation Therapy (IMRT) Have Fewer Subsequent Days of Hospitalization (DOH) than Do Patients Undergoing Conventional Radiation Therapy (CRT) in the SEER-Medicare Linked Database.C.P. Gross, P.M. Soulos, R. Sharma, D.V. Makarov, R.H. Decker, B.D. Smith, R.A. Desai, L. Cramer, J.B. Yu.
Poster Presentation - Temporal Trends in the Treatment of Elderly Men with Low and Moderate Risk Prostate Cancer: The Effect of Life Expectancy on the Administration of Curative Therapy . A.C. Raldow, R. Sharma, C. Presley, L. Cramer, J.B. Yu, P. Soulos, C.P. Gross.
Susan Higgins
Poster Presentation - Postoperative Vaginal Brachytherapy Alone (VB) Provides Equally Effective Treatment With Less Toxicity Than External Beam Radiation and Vaginal Brachytherapy (EXT + VB) In The Treatment of Stage II Endometrial Adenocarcinoma.SL Galper, J Harrington, E Ratner, Y Deng, D Zelterman, P Hui, TJ Rutherford, SA Higgins.
Ruth McCorkle
Educational Session - Cancer as a Chronic Illness
Meena Moran Educational Session - Breast Cancer Management: Early Stage Disease
Jonathan Sunshine
Panel Session - Physician Self-Referral and Radiation Oncology: Curable Problem or Fatal Affliction?
Lynn Wilson
Best of ASTRO
James Yu Poster Presentation - Head and Neck Cancer (HNC) Patients Undergoing Primary Radiation with Intensity Modulated Radiation Therapy (IMRT) Demonstrate Improved Overall Survival (OS) Compared to Those Undergoing Conventional Radiation Therapy (CRT) in the SEER-Medicare Linked Database . J.B. Yu, P.M. Soulos, R. Sharma, D.V. Makarov, R.H. Decker, B.D. Smith, R.A. Desai, L.D. Cramer, C.P. Gross.
Educational Session - Cancer Emergencies
Daniel Morgensztern, MD Joins Yale Cancer Center I am pleased to welcome Daniel Morgensztern to Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven. Daniel's clinical expertise in lung cancer and experience in clinical trial development will continue to strengthen our ability to offer the most advanced treatments to our patients.
Dr. Morgensztern is an Assistant Professor of Medical Oncology and will join the Yale Cancer Center Developmental Therapeutics Research Program.
In addition, he will be the physician director for the Smilow 12 inpatient unit for patients with solid tumors.
Deadline Monday: Yale Cancer Center Research Prize and Award for Clinical ExcellenceYale Cancer Center is pleased to announce two annual, competitive awards in the areas of excellence in research and clinical care.Each award will be announced at the Yale Cancer Center Conclave to be held on Monday, November 22, 2010. Yale Cancer Center Research Prize: This award is in support of excellence in the areas of basic science, translational research, clinical research, cancer prevention and control, epidemiological research, or case review. It will be awarded to the Cancer Center investigator whose paper is considered to have had the greatest impact on their field this year.
Yale Cancer Center Award for Clinical Excellence: This award will be given to the physician who best exemplifies excellence in clinical care including superb clinical skills, use of a patient and family centered approach to care, and inclusion of a multi-disciplinary care model.
Deadline Monday: American Cancer Society Institutional Research Grant
Yale Cancer Center is pleased to announce a competition for grants for new Yale Assistant Professors. The awards are to support innovative work in the broad field of basic, translational, clinical, and prevention/control cancer research by new investigators.
These grants are restricted to investigators who have not already received federal research grant support or a previous ACS-IRG award. One-year grants will provide up to $40,000 for each project. Yale Cancer Center members and non-members are encouraged to apply.
For more information, please contact Jan Zulkeski
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Julie Ann Sosa, MD was an invited speaker to present, Randomized Phase 2/3 Trial of a Tumor Vascular Disrupting Agent Fosbretabulin (CA4P) with Carboplatin and Paclitaxel in Anaplastic Thyroid Cancer: Interim Safety and Efficacy Results of the FACT Trial, earlier this month at the European Society of Medical Oncology in Milan, Italy. Yale was the second highest accruing center to this trial in the world. Howard Hochster, MD will be running the NYC Marathon on November 7th (his 19th time!) to raise money for Team Continuum, a cancer charity founded by a cancer survivor to assist patients undergoing chemotherapy with their needs not covered by the medical system. Team Continuum will have about 250 runners this year and YCC/Smilow is submitting a grant to support families of patients with long-term stays and patient-navigators.
Anyone wishing to support this charity through Dr. Hochster's run can donate here.
Donate >>
Kenneth Roberts, M D was an invited speaker at the 8th International Symposium on Hodgkin Lymphoma in Cologne, Germany to present Second Malignancies after Hodgkin's Lymphoma : The Thirty-Five Year Yale University Experience. Coauthors from Yale included: Kenneth B. Roberts, MD, Bilal Olmer, MD, Carolyn Demsky, APRN, Rong Wang, BS, Gary Kupfer, MD, PhD, Dennis Cooper, MD, Stuart Seropian, MD, Nina S. Kadan-Lottick, MD, MPH, and Xiaomei Ma, PhD. The study showed that with the change in managing Hodgkin Lymphoma from radical radiotherapy to combined chemotherapy using less alkylating agents and low-dose involved-field radiotherapy, there has been a marked reduction in secondary cancers. Melinda Irwin, PhD has been awarded a $150k grant from the American Institute for Cancer Research to do a weight loss trial in women with breast cancer.The title of the project is Telephone vs. In-Person Weight Loss Counseling on Weight, Body Fat, and Serum Markers in Breast Cancer Survivors. David Carlson , PhD, Assistant Professor of Therapeutic Radiology, in the section of Radiological Physics, recently returned from the meeting of the Radiation Research Society in Maui. David was an invited speaker in a symposium at that meeting, where he presented a paper entitled, Using Monte Carlo DNA damage simulations and deterministic repair models to examine the putative mechanisms of radiation-induced cell death. This paper was based on and extended David's work that won last year's Radiation Research Society's Editors' Award for the outstanding paper published by a young investigator in Radiation Research.
Howard Hochster, MD presented a poster at the NCI-ASCO-EORTC meeting last week, entitled A Dose Finding and Phase II Study of the MEK-inhibitor Selumetinib (AZD6244) and Irinotecan as Second Line Therapy in Patients with KRAS or BRAF-mutated Colorectal Cancer.
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Recent Publications
Primary trastuzumab resistance: new tricks for an old drug
Wilken JA, Maihle NJ. Ann N Y Acad Sci
. 2010 Oct;1210(1):53-65.
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Should the 7th Edition of the Lung Cancer Stage Classification System Change Treatment Algorithms in Non-small Cell Lung Cancer?
Boffa DJ, Detterbeck FC, Smith EJ, Rami-Porta R, Crowley J, Zelterman D, Tanoue L, Kim AW, Goldstraw P. J Thorac Oncol
. 2010 Nov;5(11):1779-1783.
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The Future of Radiation Oncology in the United States From 2010 to 2020: Will Supply Keep Pace With Demand? Smith BD, Haffty BG, Wilson LD, Smith GL, Patel AN, Buchholz TA. J Clin Oncol . 2010 Oct 18. Read More >>
EGFs and ERBBs-brief history and prospects. Stern DF. Semin Cell Dev Biol . 2010 Oct 20. Read More >> Langerhans cells are not required for graft-versus-host disease. Li H, Kaplan DH, Matte-Martone C, Tan HS, Venkatesan S, Johnson K, Demetris A, McNiff J, Shlomchik M, Shlomchik WD. Blood . 2010 Oct 13. Read More >>
Lymphotoxin-alpha contributes to lymphangiogenesis. Mounzer RH, Svendsen OS, Baluk P, Bergman CM, Padera TP, Wiig H, Jain RK, McDonald DM, Ruddle NH. Blood . 2010 Sep 23;116(12):2173-82. Epub 2010 Jun 21. Read More >> Expression and somatic mutations of SDHAF2 (SDH5), a novel endocrine tumor suppressor gene in parathyroid tumors of primary hyperparathyroidism. Starker LF, Delgado-Verdugo A, Udelsman R, Björklund P, Carling T. Endocrine . 2010 Oct 23. Read More >> Advances in genome-wide DNA methylation analysis. Gupta R, Nagarajan A, Wajapeyee N. Biotechniques . 2010 Oct;49(4):iii-xi. Read More >> EGFR isoforms and gene regulation in human endometrial cancer cells. Albitar L, Pickett G, Morgan M, Wilken JA, Maihle NJ, Leslie KK. Mol Cancer . 2010 Jun 25;9:166. Read More >>
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Inside Yale Cancer Center
Breast Cancer Awareness and Genetic Testing Read Articles Featuring Interviews with Dr. Anees Chagpar and Ellen Matloff Read More >>
Read the Latest Issue of YaleCares October's issue highlights survivors' concerns about returning to work. Read More >>
Subscribe to Yale Cancer Center Answers on iTunes
Yale Cancer Center's weekly radio program on CT Public Radio is ranked number 2 in the world for cancer programs on iTunes. Subscribe to the show.
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Cancer Bytes
Hosted by Ellen Matloff, listen to the latest interview with Laura.Learn More >>
Yale Cancer Center Grand Rounds
Video presentations from Yale Cancer Center members are now available online.
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DirectConnect Archives
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Events
October 31; 6:00 PM Yale Cancer Center Answers WNPR Cancer Survivorship Tara Sanft, MD
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November 2; 11:00 AM Therapeutic Radiology Seminar WWW 201 Nucleotide Probes for DNA Polymerase Beta Charles E. McKenna, PhD
Learn More >> (PDF)
November 2; 12:00 PM Yale Cancer Center Grand Rounds 55 Park Street
Molecular and Epidemiological Studies of Gynecological Cancer Herbert Yu, PhD Axillary Management of Breast Cancer Patients: Tailoring Therapy Anees Chagpar, MD Learn More >> (PDF)
November 7; 6:00 PM Yale Cancer Center Answers WNPR Lung Cancer Thomas Lynch, Jr., MD Learn More >>
November 9; 12:00 PM Yale Cancer Center Grand Rounds 55 Park Street Novel Approaches and Targets for Smoking Cessation Interventions
Benjamin Toll, PhD The Surgical Treatment of Musculoskeletal Tumors Gary Friedlaender, MD Learn More >> (PDF)
November 10; 11:00 AM Radiobiology and Radiotherapy Program Conference WWW 201 A Novel Role of High Order Chromatin Structure in Preventing Genomic Instability Andrew Xiao, PhD Learn More >>
November 10; 12:00 PM YCC Special Seminar WWW 208 Is there a Role for Trastuzumab in Adjuvant Therapy of HER2 Negative Early Breast Cancer? Charles E. Geyer, Jr., MD Learn More >> (PDF)
November 11; 12:00 PM Schwartz Rounds 55 Park Street Family Centered Care Versus Interference
Hosted by Tom Lynch Learn More >> (PDF)
November 11; 4:00 PM Edith Hsiung Memorial Lectureship in Diagnostic Virology Hope 216 Genomics-based Detection of Novel Viral Pathogens: Skating to Where the Puck is Gonna Be Donald Ganem, PhD Learn More >> (PDF)
November 11; 5:00 PM Innovations in the Treatment of Lung Cancer CME Dinner Inn at Middletown Presentations from members of the Thoracic Oncology Program Learn More >>
November 12; 1:00 PM Developmental Therapeutics and Molecular Virology Seminar SHM I-116 pH-Dependent Transmembrane PeptideInsertion: Mechanism and Uses in Drug Delivery and Tumor Imaging Donald M. Engelman, PhD Learn More >>
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Funding Opportunities
AACR Calls for SU2C Innovative Research Grant Letters of Intent The American Association for Cancer Research calls upon the cancer research community to submit Letters of Intent for Stand Up To Cancer's Innovative Research Grants (IRG), which support the next generation of extraordinary cancer research leaders in their quest to conquer cancer.
The grants will provide funding of up to $750,000 over a three-year period.
IRGs offer financial support to scientists pursuing novel, high-risk, but potentially high-reward cancer research proposals that have significant potential for translational application and hold great promise for advancing SU2C's overarching goal of improving and saving lives. Proposals may focus on any discipline within basic, translational or clinical research, provided that these criteria are met.
Letter of Intent Deadline: 12:00 p.m. ET on Monday, Nov. 15, 2010.
Learn More >>
Sidney Kimmel Foundation Translational Science Award The foundation provides these awards specifically for physicians engaged in translational science. Applicants must demonstrate a significant personal involvement in the laboratory component of the translational project described. The translational research may involve primarily animal studies but must include reasonable application to subsequent human investigation.
Sidney Kimmel Foundation for Cancer Research Scholars Award Each year the Kimmel Foundation expects to select up to ten grant recipients for the Scholars Award who will receive $100,000 per year for two years. Qualified applicants must hold an MD, PhD, or equivalent graduate degree and must perform research in an American not-for-profit institution during the period of Kimmel Foundation support. The Kimmel Foundation is seeking accomplished young investigators dedicated to a career in cancer research. Applications are limited to those who achieved the equivalent rank of Assistant Professor on or after July, 2007.
Doris Duke Charitable Foundation Clinical Scientist Development Award For assistant professors with an MD or MD/PhD working in any disease area as they begin their careers as independent clinical researchers. Candidates must have been appointed to their first full-time faculty level position between January 1, 2006 and January 1, 2011. At least 75% of professional time must be devoted to research, overall. $150,000 per year direct costs for 3 years.
Alex's Lemonade Stand Foundation Grants distributed from Alex's Lemonade Stand Foundation are designed to fill critical voids in current pediatric cancer research. Innovation, Young Investigator, and Program Innovation Awards are available. Letter of Intent Deadline: December 1, 2010 |
New Faculty Recruits
Anees Chagpar Surgical Oncology
Lieping Chen Immunobiology
Deborah Chirnomas Pediatric Oncology
Leonard Farber
Medical Oncology
Mark Faries
Surgical Oncology
Howard Hochster Medical Oncology
Erin Hofstatter
Medical Oncology
Nina Horowitz Surgical Oncology
Michael Hurwitz Medical Oncology
Benjamin Judson Otolaryngology
Arthur Levy Medical Oncology
Miguel Materin Ophthalmology
Daniel Morgensztern Medical Oncology
Don Nguyen
Pathology
Abhijit Patel Therapeutic Radiology Nikolai Podoltsev Hematology
Katie Politi
Pathology
Tara Sanft Medical Oncology
Stacey Stein Medical Oncology
Narendra Wajapeyee
Pathology
Qin Yan
Pathology
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Submissions
Please submit your recent publication and grant announcements to:
Renee Gaudette
Director, Public Affairs and Marketing
renee.gaudette@yale.edu
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