Jaime Grutzendler MD

Associate Professor of Neurology and of Neurobiology; Director, Center for Experimental Neuroimaging

Biographical Info

Dr. Grutzendler obtained his MD at Universidad Javeriana in Bogota, Colombia where he was born and raised. He completed a medical internship in Internal Medicine and a residency in Neurology at Washington University/Barnes-Jewish Hospital in St. Louis. This was followed by a combined clinical and research fellowship in the Alzheimer Disease Research Center and the Department of Neurobiology at Washington University and further neurobiology research training at the Skirball Institute of New York University.
His research laboratory is interested in understanding various aspects of brain development and pathology using in vivo disease models. One area of interest is the development and pathology of the microvasculature and the "neuro-glio-vascular unit"(NGVU), neurovascular coupling, tissue oxygenation. The lab uses optical imaging techniques to better understand the dynamic behavior of cells within the NGVU (neurons, endothelium, astrocytes, pericytes, microglia and oligodendrocytes), how these cells interact with each other and how interactions are disrupted in injury,vascular and neurodegenerative disorders. Dr. Grutzendler's clinical interests focus on neurodegenerative disorders with special emphasis in dementias such as Alzheimer's disease.

Education & Training

Universidad Javeriana School of Medicine (1991)
Washington Univeristy in St. Louis, Neurology (1995 - 1998)
Research Fellow
Washington University in St. Louis, Neurobiology (1998 - 2000)
Clinical Fellow
Washington University in St. Louis, Alzheimer's Disease Research Center (1998 - 2000)
Postdoctoral Fellow
Skirball Institute/New York University, Molecular Neurobiology Program (2001 - 2003)
Washington University in St. Louis, Internal Medicine (1994 - 1995)
Board Certification
Neurology, Board Certified  (2003)

Honors & Recognition

  • NIH Director’s Transformative Research Award
  • McCance Yale Scholar
  • New Scholar Award
    Ellison Foundation (2004)
  • Brain and Immunoimaging Award
    Dana Foundation (2004)
  • American Society for Clinical Investigation
    Elected member (2012)

Edit Profile