Wendell Gray Yarbrough, MD, MMHC, FACS

Professor of Surgery (Otolaryngology) and of Pathology; Section Chief, Otolaryngology; Co-Director Molecular Virology Research Program; Director, Head & Neck Cancer Program, Smilow Cancer Hospital

Research Interests

DNA Damage; Head and Neck Neoplasms; NF-kappa B; Tumor Suppressor Proteins; Human Papillomavirus DNA Tests; Diseases

Research Organizations

Surgery: Otolaryngology: Head & Neck Cancer Program

Pathology

Cancer Center: Virus and Other Infection-associated Cancers

Faculty Research

HPV

Virology laboratories

Research Summary

Identification of tumor suppressors in head and neck cancers; Understanding of tumor growth; Association between viruses and the development of cancer, particularly the link between the human papillomavirus and head and neck cancers.

Specialized Terms: Head and neck oncology; Salivary oncology; Mouse modeling of human cancer; Human-in-mouse cancer models; Tumor suppressor activity; Molecular defects in cancer; NF-kappa B; NF-kB; Signaling; DNA damage; Human papilloma virus; HPV

Selected Publications

  • Characterization of HPV and host genome interactions in primary head and neck cancers.

    Characterization of HPV and host genome interactions in primary head and neck cancers. Parfenov M, Pedamallu CS, Gehlenborg N, Freeman SS, Danilova L, Bristow CA, Lee S, Hadjipanayis AG, Ivanova EV, Wilkerson MD, Protopopov A, Yang L, Seth S, Song X, Tang J, Ren X, Zhang J, Pantazi A, Santoso N, Xu AW, Mahadeshwar H, Wheeler DA, Haddad RI, Jung J, Ojesina AI, Issaeva N, Yarbrough WG, Hayes DN, Grandis JR, El-Naggar AK, Meyerson M, Park PJ, Chin L, Seidman JG, Hammerman PS, Kucherlapati R; the Cancer Genome Atlas Network; the Cancer Genome Atlas Network. Proc Natl Acad Sci U S A. 2014 Oct 13. pii: 201416074. [Epub ahead of print]

  • Conclusions about human papillomavirus-related malignancies.

    Conclusions about human papillomavirus-related malignancies. Yarbrough WG, Rosenthal E. Head Neck. 2014 Jun;36(6):826-7. doi: 10.1002/hed.23378. Epub 2013 Sep 2.

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