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Program Members

Co-Leaders

Bosenberg, Marcus W.

Clinical Interests:Dermatopathology; melanoma; skin cancer

  • Office:(203) 737-3484
  • Appt:(203) 785-4094

Pusztai, Lajos

Clinical Interests:breast cancer; cancer genetics.

  • Appt:(203) 200-2328

Members

Bale, Allen Everett

Research Interests:Molecular Mechanisms of Cancer; Predisposition and Developmental Defects; DNA Diagnostics; Birth Defects; Cancer; Fanconi; Genetics; Hedgehog; Multiple Endocrine Neoplasia; Patched; Skin Cancer; Tumor Suppressor

    Baserga, Susan J

    Research Interests:Ribosome biogenesis; RRNA processing; U3 RNP structure and function; RNA helicases; Polymerase I transcription and processing

      Bosenberg, Marcus W.

      Research Interests:Melanocytic neoplasms; Soft tissue tumors; Cutaneous lymphoma; Genodermatoses

      • Office:(203) 737-3484
      • Appt:(203) 785-4094

      Braddock, Demetrios

      Research Interests:Structural biology; Hematopathology; Genitourinary Pathology

      • Office:(203) 737-1278

      Carling, Tobias

      Research Interests:Improved outcomes in minimally invasive endocrine surgery; Molecular genetics of endocrine tumors of the thyroid, parathyroid, adrenal (hyperaldosteronism, hypercortisolism, adrenal cancer, pheochromocytoma) and endocrine pancreas; Familial endocrine tumor susceptibility syndromes; Regulation of calcium homeostasis

      • Appt:(203) 737-2036

      Carrasco, Nancy

      • Office:(203) 785-4117

      Choate, Keith Adam

      Research Interests:Human Genetics; Genodermatoses; Gene Discovery; Genetic Mosaicism; Disorders of keratinization; Mosaic skin disorders; Stem cell biology; Developmental biology; Epidermal differentiation; Sequencing technology

      • Appt:(203) 789-1249

      Choi, Jaehyuk

      • Appt:(203) 789-1249

      Cooley, Lynn

      Research Interests:Molecular Genetics of Drosophila Oogenesis; Actin Cytoskeleton Regulation; Drosophila; Oogenesis; Ring Canal; Ovarian Muscle Function

      • Office:(203) 432-2733
      • Lab:(203) 785-2675
      • Appt:(203) 785-5067

      Costa, Jose

      Research Interests:Oncology; Carcinogenesis; Tumor development and progression; Advanced diagnostics; Molecular diagnostics; Diagnosed genetic alterations in tumors; Cancer risk detection by mutational load distribution analysis

      • Office:(203) 785-5803

      Garen, Alan

      Research Interests:Development; Genetics; Medical Sciences; Molecular Biology

        Gerstein, Mark B

        Research Interests:Biochemistry; Bioinformatics; Biophysics; Computational Biology; DNA; Genomics; Molecular Simulation; Proteins; Sequence Alignment; Structural Biology

        • Office:(203) 432-6105

        Giraldez, Antonio J.

        Research Interests:Developmental Biology; Non-coding RNAs; Post-transcriptional regulation; microRNAs; Gene regulatory networks; Systems Biology; Zebrafish

        • Office:(203) 785-5423

        Gunel, Murat

        Research Interests:Molecular genetics and biology of brain aneurysms and cavernous malformations; Molecular genetics of brain development

        • Office:(203) 737-2096
        • Appt:(203) 737-2096

        Halaban, Ruth

        Research Interests:Genes controlling differentiation, proliferation; malignant transformation of melanocytes; Growth factors and receptor kinases; Signal transduction; Epigenetic modification and gene expression; Markers for melanoma; Next-Generation sequencing; mutations

        • Office:(203) 785-4352

        Halene, Stephanie

        Research Interests:Hematopoiesis; Myeloid differentiation; Leukemia; Myelodysplasia

        • Appt:(203) 200-4363

        Hattangadi, Shilpa

        Research Interests:Terminal erythroid development; Hematopoiesis; Bone marrow failure; Red cell aplasia; Chromatin condensation; Nuclear protein export; Proteomics; Genomics; Transcriptional regulation; Histone modification; Post-translational modification of hematopoietic regulators

        • Appt:(203) 785-4640

        Hatzis, Christos

        Research Interests:Personalized medicine; Molecular diagnostics; Cancer heterogeneity; Next generation sequencing; Diagnostic study design

          Hofstatter, Erin Wysong

          • Appt:(203) 200-2328

          Hoh, Josephine

          Research Interests:Interactions among genes; Environmental exposures

          • Office:(203) 785-2738
          • Lab:(203) 737-6007

          Ivanova, Natalia B.

          Research Interests:Embryonic and somatic stem cells; Vertebrate development; Functional genomics; Systems biology

            Katz, Samuel G.

            • Office:(203) 785-2757

            Khan, Sajid A

            Research Interests:Cancer; metastasis; oligometastasis; microRNA; gene expression profiling; microsatellite instability; clinical outcomes; surgical resection; surgical palliation; liver metastasis; pancreas; gastric cancer; gastrointestinal stromal tumors (GIST); early onset colorectal cancer; sarcoma

            • Office:(203) 337-8507
            • Appt:(203) 337-8507

            Kidd, Kenneth Kay

            Research Interests:Complex Human Disorders; Neuropsychiatric Disorders; Human Population ; Genetics; Human Evolution

            • Office:(203) 785-2654
            • Lab:(203) 785-2653

            Kluger, Yuval

            Research Interests:Signal processing and dimensional reduction of genome-wide data; Local and non-local genomic pattern recognition; Identification of cancer subclones with proliferation and invasion potential in heterogeneous cancer biopsies

            • Office:(203) 737-6262

            Konigsberg, William H

            Research Interests:Blood Coagulation; DNA Replication; Genetics; Proteins and Macromolecules

              Krause, Diane S

              Research Interests:Bone Marrow Transplantation; Stem Cells; Cell and Molecular Hematology; Leukemia

              • Office:(203) 737-1678

              Lazova, Rossitza

              Research Interests:Spitz nevi; Spitzoid melanocytic neoplasms; Malignant melanoma; Melanocytic nevi on special anatomic sites; Atypical Spitzoid neoplasms

              • Office:(203) 785-4094
              • Appt:(203) 785-4094

              Leffell, David J.

              Research Interests:Molecular biology of basal cell carcinoma, squamous cell carcinoma; Wound healing; Skin cancer epidemiology

              • Appt:(203) 785-3466

              Lengyel, Peter

              Research Interests:p200 family proteins; mammalian differentiation; cell proliferation; interferons

                Li, Peining

                Research Interests:Cytogenetic and genomic analysis; Dissection of genetic mechanisms for growth regulation, mental development, and cancer progression

                • Office:(203) 785-6317
                • Appt:(203) 785-6317

                Lifton, Richard P

                Research Interests:Molecular genetics of common human diseases

                • Office:(203) 737-4420

                Lin, Haifan

                Research Interests:Stem cell RNA-mediated epigenetic programming, post-transcriptional regulation

                • Office:(203) 785-6239
                • Lab:(203) 785-6215

                Llor, Xavier

                Research Interests:Mismatch Repair Proficient Hereditary Non-Polyposis Colorectal Cancer; MSS-HNPCC: Lynch syndrome; Colorectal Cancer Disparities: Colorectal Cancer in African Americans

                • Appt:(203) 200-5083

                Lu, Jun

                Research Interests:Non-coding RNAs in blood stem cell differentiation and malignancies; MicroRNA-mediated control of embryonic stem cell fates; MicroRNA mechanisms

                • Office:(203) 737-3426

                Mane, Shrikant M.

                • Office:(203) 737-3104
                • Lab:(203) 737-3058

                Materin, Miguel A

                Research Interests:Role of cytogenetics in ocular oncology for diagnosis and prognosis; Improving diagnostic and treatment methods for eye tumors

                • Appt:(203) 200-3937

                McGrath, James Michael

                Research Interests:Developmental Genetics; Genetic Imprinting; Embryogenesis; Spermatogenesis

                • Office:(203) 785-2686
                • Appt:(203) 785-2660

                Neugebauer, Karla

                Research Interests:pre-mRNA splicing, transcription, gene architecture, SR proteins, cap-binding complex, RNA-protein interactions, Cajal bodies, organization of the cell nucleus, zebrafish embryogenesis.

                • Lab:(203) 785-2358

                Noonan, James

                Research Interests:Human Evolution; Evolutionary Dynamics of Gene Regulation; Synthetic Biology; Applications of Ultra-High Throughput Sequencing Technologies; Comparative and Functional Genomics in Vertebrates

                  Pillai, Manoj M

                  • Office:(203) 737-6403
                  • Lab:(203) 737-6990

                  Prasad, Manju

                  Research Interests:Endocrine, Head & Neck Pathology; Genotype-phenotype correlation in tumors; Protein expression and biomarkers in tumor tissues, and their diagnostic & prognostic relevance

                  • Office:(203) 785-4862

                  Pusztai, Lajos

                  Research Interests:Breast cancer; Translational cancer research; Developing pharmacogenomic markers of response to breast cancer therapy and identifying methods to select the optimal treatment for each patient

                  • Appt:(203) 200-2328

                  Schwartz, Peter E

                  Research Interests:Ovarian Cancer; Uterine; Vaginal; Cervical and vulvar cancer; Screening for ovarian cancer

                  • Office:(203) 785-4014
                  • Appt:(203) 785-4014

                  Seli, Emre U

                  Research Interests:Translational regulation of gene expression during oocyte end early embryo development; Assessment of embryo viability in assisted reproductive technologies; Pathogenesis of endomentriosis.

                  • Office:(203) 785-7873
                  • Appt:(203) 785-4708

                  Shadel, Gerald S

                  Research Interests:Mitochondria; Mitochondrial Genetics and Biogenesis; Mitochondrial Dysfunction in Human Disease and Aging; Mechanisms of mtDNA Transcription and Mitochondrial Translation; Signaling Pathways that Sense and Control Mitochondrial Function; Cancer; Immune System Signaling

                  • Office:(203) 785-2475

                  Sklar, Jeffrey L.

                  Research Interests:Molecular biology of human disease, especially cancer; Molecular biologic methods of disease diagnosis; Cancer-related genes and their functions in neoplasia and normal cellular physiology; Chromosomal structure and chromosomal abnormalities in genetic and neoplastic disorders; Immunogenetics

                  • Office:(203) 785-6836

                  Strout, Matthew

                  Research Interests:Cancer genetics; Lymphomagenesis; Leukemogenesis; Immune diversification; Epigenetics; Tissue banking; Targeted therapy

                  • Office:(203) 785-7002
                  • Lab:(203) 737-6425
                  • Appt:(203) 200-4363

                  Taylor, Hugh S.

                  Research Interests:Endometriosis; Stem Cells; Embryo Implantation; Asherman's Syndrome; Menopause; Uterine Development; Endorcrine Disruption; Developmental Programming

                  • Office:(203) 785-4001
                  • Appt:(203) 785-4708

                  Townsend, Jeffrey

                  • Office:(203) 737-7042
                  • Lab:(203) 785-6800

                  Udelsman, Robert

                  Research Interests:Hyperparathyroidism, Primary Papillary Thyroid Microcarcinoma, Parathyorid glands, Hyperparathyroidism in patients using lithium, endocrinology, adrenal glands

                  • Office:(203) 785-2697
                  • Appt:(203) 785-2697

                  Weatherbee, Scott Donald

                  Research Interests:Limb development; Developmental genetics; Organogenesis; Mouse genetics; Signaling pathways; Embryogenesis

                    Weissman, Sherman Morton

                    Research Interests:Globin and Histocompatibility Gene Structure and Function; Genome wide mapping of gene activity and chromosome structure in man; Transcription Factors; Lymphocyte and myeloid Transcription Networks; Stem Cells; Cell Senescence; Methods for Molecular Genetics

                    • Office:(203) 737-2281

                    Xiao, Andrew Zhuo

                    Research Interests:Chromatin biology; Histone variants; Modifications and chromatin remodeling complexes; Cellular reprogramming (iPS) and stem cell biology; Mammalian neural crest cell; Mammalian DNA damage response

                    • Office:(203) 737-3650
                    • Lab:(203) 785-5111

                    Xu, Mina LuQing

                    Research Interests:Peripheral T-cell lymphoma, NOS; Classical hodgkin lymphoma; EBV-related lymphoproliferative disorders; Hemophagocytic lymphohistiocytosis; Hematopoietic stem cell niche

                    • Office:(203) 737-6135

                    Xu, Tian

                    Research Interests:Genetic methodology; Cancer biology; Food and metabolism; Developmental mechanisms

                      Yan, Qin

                      Research Interests:Epigenetics; Gene regulation; Cancer biology; Stem cell biology

                      • Office:(203) 785-6672

                      Zhao, Hongyu

                      Research Interests:Statistical genomics and proteomics; Bioinformatics; Data integration; High dimensional data; Network and graphical models; Disease risk prediction; Herbal medicine; Microbiome

                      • Office:(203) 785-3613