Karl L. Insogna, MD

Professor of Medicine (Endocrinology); Director, Yale Bone Center; Ensign Professor of Medicine without Term, Yale University, Department of Internal Medicine; Associate Director, Yale Center for X-Linked Hypophosphatemia; Attending Physician (Internal Medicine), Yale-New Haven Hospital

Clinical Interests

  • Bone Diseases, Endocrine
  • Hypercalcemia
  • Hypocalcemia
  • Osteoblasts
  • Osteopetrosis
  • Osteoporosis
  • Rickets
  • Hypophosphatemia
  • Familial Hypophosphatemic Rickets
  • Rickets, Hypophosphatemic

Patient Care

Accepts new patients? No
Patient Type: Adult; Geriatric
Referrals: From physicians only

Patient Care Organizations

Internal Medicine: Diabetes Research Center | Endocrinology: Bone Center (Endocrinology) | Liver Center

Center for X-Linked Hypophosphatemia, Yale

WHRY Pilot Project Program Investigators

Yale Cancer Center

Yale Medicine

Office of Cooperative Research

Board Certifications

  • Internal Medicine AB of Internal Medicine (1979)

  • Endocrinology, Diabetes &Metabolism AB of Internal Medicine (1983)

Clinical Trials

Conditions Study Title
Children's Health Multicenter,Single-arm Study to Evaluate Efficacy, Safety, & Pharmacokinetics of Denosumab in Children w/ OI (OI)
Children's Health, Diseases of the Endocrine System, Immune System Study of the Safety, Pharmacodynamics and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)
Diseases of the Endocrine System, Diseases of the Musculoskeletal System Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH)

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