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Linda M. Niccolai PhD, ScM

Associate Professor of Epidemiology (Microbial Diseases); Director, HPV-IMPACT Project (Emerging Infections Program); Deputy Director, Office International Training (CIRA); Director, Development Core at Center for Interdisciplinary Research on AIDS; Member, Yale Cancer Center (Cancer Prevention and Control)

Research Interests

Sexually transmitted infections; Human papillomavirus vaccine; HIV; Epidemiologic methods; Qualitative research

Current Projects

  • Monitoring Impact of Human Papillomavirus Vaccine in Connecticut
  • Identifying and Quantifying Barriers to Uptake of HPV vaccine
  • Feasibility of a school-based intervention for HPV vaccination
  • Increasing HPV vaccination coverage among adolescents in Connecticut

Research Summary

Professor Niccolai is an epidemiologist whose research is primarily focused on sexually transmitted infections (STI), including HIV. Her main area of interest is in behavioral aspects of HIV/STI prevention. Currently, Professor Niccolai is involved in several areas of research. Her main area of research is studying uptake and impact of human papillomavirus vaccines with an emphasis on addressing health disparities. She is the Project Director of a surveillance program to monitor impact of the human papillomavirus vaccine with the Connecticut Emerging Infections Program. She is also the Principal Investigator of a mixed-methods study to identify barriers to HPV vaccination among low-income minority populations. She is currently working to identify opportunities to increase uptake in CT.

Extensive Research Description

Linda Niccolai is an associate professor in the Department of Epidemiology of Microbial Diseases at the Yale School of Public Health. She is deputy director of the Office of International Training and Director of the Development Core for Yale School of Public Health’s Center for Interdisciplinary Research on AIDS. Her research focuses on sexually transmitted infections, including HIV. Dr. Niccolai is the principal investigator of project to monitor vaccine impact for human papillomavirus (funded by CDC) and also PI of an NIH-funded mixed methods study to assess barriers to uptake of HPV vaccine.

Linda Niccolai received her Sc.M. at Harvard School of Public Health and her Ph.D. at Tulane University. She is the recipient of Connecticut Infectious Disease Society Thorton Award for Best Poster Presentation in Clinical Research in Infectious Disease and Award for Excellence in Teaching at YSPH.


Selected Publications

  • Niccolai LM, Hansen CE, Credle M, Ryan S, Shapiro ED. Parents’ views on human papillomavirus vaccination for sexually transmitted infection prevention: A qualitative study. Sexual Health 2014;11:274-9.
  • Waggaman C, Julian P, Niccolai LM. Interactive effects of individual and neighborhood race and ethnicity on rates of high-grade cervical lesions. Cancer Epidemiology 2014;38:248-252.
  • Niccolai LM, Julian PJ, Bilinski A, Mehta NR, Meek JI, Zelterman D, Hadler JL, Sosa LE. Area-based poverty, racial, and ethnic disparities in cervical cancer precursor rates in Connecticut, 2008-2009. American Journal of Public Health 2013;103:156-63.
  • Niccolai LM, Julian P, Meek J, McBride V, Hadler J, Sosa L. Declining rates of high-grade cervical lesions in young women in Connecticut, 2008-2011 Cancer Epidemiology, Biomarkers & Prevention 2013 (in press).
  • Niccolai LM, Russ C, Julian PJ, Hariri S, Sinard J, Meek JI, McBride V, Markowitz LE, Unger ER, Hadler JL, Sosa LE. Individual and geographic disparities in human papillomavirus types 16/18 in high-grade cervical lesions: Associations with race, ethnicity, and poverty. Cancer 2013 (in press).
  • Niccolai LM, King EJ, Eritsyan K, Safiullina L, Rusakova MM. “In different situations, in different ways”: Male sex work in St. Petersburg, Russia. Culture, Health, and Sexuality 2013;15:480-93.
  • Niccolai LM, Livingston KA, Laufer AS, Pettigrew MM. Behavioral sources of repeat Chlamydia trachomatis infections: The importance of different sex partners. Sexually Transmitted Infections 2011;87:248-253.

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