Nancy Carrasco MD

Professor of Cellular and Molecular Physiology

Selected Publications

  • Nicola, JP., Carrasco, N*. and Amzel, LM* (2014) “Physiological Na+ concentra-tions enhance the I- affinity of the Na+/I- symporter (NIS)” Nature Comm 3;5:3948. doi: 10.1038/ncomms4948.PMID: 24888603 *co-corrresponding authors Highlighted in Science (2014), 344, 1355.
  • Li W, Nicola JP, Amzel LM, and Carrasco N (2013) “Asn441 plays a key role in folding and function of the Na+/I- symporter (NIS)” FASEB J May 6. [Epub ahead of print] PMID: 23650190
  • Paroder V, Nicola JP, Ginter CS, and Carrasco N. (2013) “The iodide transport defect-causing mutation R124H: a d-amino group at position 124 is critical for maturation and trafficking of the Na+/I- symporter (NIS)” J. Cell Science May 20. [Epub ahead of print] PMID: 23690546
  • Paroder-Belenitsky M, Maestas MJ, Dohán O, Nicola JP, Reyna-Neyra A, Follenzi A, Dadachova E, Eskandari S, Amzel LM, Carrasco N. (2011) “Mechanism of anion selectivity and stoichiometry of the Na+/I- symporter (NIS)” Proc Natl Acad Sci USA. 108, 17933-17938. Epub 2011 Oct 19. Evaluated by “Faculty of 1000.”
  • Roepke TK, King EC, Reyna-Neyra A, Paroder M, Purtell K, Koba W, Fine E, Lerner DJ, Carrasco N, Abbott GW (2009). "kcne2 deletion uncovers its critical role in thyroid hormone synthesis" Nature Medicine 15, 1186-1194. Epub Sep 20. Evaluated in: “Faculty of 1000.”, 2009.
  • •Dohán O, Portulano C, Basquin C, Reyna-Neyra A, Amzel LM, and Carrasco N. (2007) "The Na+/I- symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate" Proc Natl Acad Sci USA Dec 104, 20250-20255. Epub 2007 Dec 11. Highlighted in: "This week in PNAS." Evaluated by “Faculty of 1000.”
  • De la Vieja A, Reed M, Ginter CS, and Carrasco N. (2007) "Amino acid residues in transmembrane segment IX of the Na+/I- symporter (NIS) play a role in its Na+ dependence and are critical for transport activity" J Biol Chem 282, 25290-25298. Epub Jul 2.

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