Richard A Flavell PhD, FRS

Sterling Professor of Immunobiology; Investigator, Howard Hughes Medical Institute; Department Chair, Immunobiology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Immunology

Stem Cell Center, Yale: Stem Cell Niche and Homing | Stem Cell Self-Renewal and Cell Symmetry

Cancer Immunology

Vascular Biology and Therapeutics Program

Immunobiology: Lymphocyte Development | HTI | Flavell Lab

Parasitology Program

Skin Diseases Research Center, Yale

SPORE in Skin Cancer

Diabetes Research Center

NIH T32 Program

Immunology and Immunotherapy

Research Interests

Animal Models; Autoimmunity; Diabetes; Gene Expression; Gene Transfer; Genes; Immune System; Lyme Borreliosis Or Lyme Disease; Molecular Cellular Entities; Recombinant DNA; Transgenic Animals; Autoimmunity; Knockout Mice; Lyme Disease; T Cell Lineages; Tolerance; Transgenic Mice  more...


  • Ph.D., Hull University, 1970

Selected Publications

  • Henao-Mejia J.*, Williams A*, Goff L.A., Staron M, Licona-Limón P, Kaech S.M., Nakayama M, Rinn J.L., Flavell R.A. miR-181 is a cellular metabolic rheostat essential for NKT cell development. Immunity. (2013). PMC3738211
  • Huber S, Gagliani N, Zenewicz LA, Huber FJ, Hedl W, O’Connor W, Murphy AJ, Valenzuela DM, Yancopoulos GD, Booth CJ, Cho JH, Ouyang W, Abraham C, Flavell RA IL-22BP axis is regulated by the inflammasome and modulates tumorogenesis in the intestine. Nature Nov 8;491(7423):259-63. (2012). PMC3493690.
  • Henao-Mejia J, Elinav E, Jin C, Hao L, Mehal WZ, Strowig T, Thaiss CA, Kau AL, Eisenbarth SC, Jurczak MJ, Camporez J-P, Shulman GI, Gordon JI, Hoffman HM, Flavell RA. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 482:179-185 (2012) Feb 1. PMC3276682



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