Richard E Peschel MD, PhD

Professor Emeritus of Therapeutic Radiology

Research Interests

Intensity modulated radiation therapy; Prostate cancer; Prostate implant; Prostate specific antigen; Radiation therapy

Research Summary

Prostate cancer is now the most common malignancy diagnosed in American males and the second leading cause of cancer deaths. Although a variety of approaches (observation, surgery, external beam radiation therapy, brachytherapy, and hormone therapy) are available for prostate cancer, a review of the historical prostate cancer data provides little evidence that the most cost-effective and efficacious therapies are being utilized. The prostate specific antigen (PSA) has revolutionized our understanding of the proper diagnosis and treatment of prostate cancer.

The clinical research programs at the Hunter Radiation Therapy Center include programs to scientifically evaluate the efficacy of surgery versus various forms of radiation therapy including implant therapy, three-dimensional conformal external beam radiation therapy, and intensity modulated radiation therapy (IMRT) for treatment of early prostate cancer. IMRT represents the newest form of radiation therapy for prostate cancer. We are using IMRT with dose escalation for all of our prostate cancer patients. We have recently received a grant from the Anna Fuller Foundation to evaluate the clinical outcomes using IMRT and a new technology called image-guided IMRT.

Selected Publications

  • Aizer AA, Yu JB, McKeon AM, Decker RH, Colberg JW, Peschel RE. Whole Pelvic Radiotherapy Versus Prostate Only Radiotherapy in THE Management of Locally Advanced or Aggressive Prostate Adenocarcinoma. Int J Radiat Oncol Biol Phys. 2009 May 21. [Epub ahead of print]
  • Colberg JW, Decker RH, Khan AM, McKeon A, Wilson LD, Peschel RE. Surgery versus implant for early prostate cancer: results from a single institution, 1992-2005. Cancer J. 2007 Jul-Aug13(4):229-32.
  • Peschel RE. Long-term outcomes after prostate implant: Wheeling, WV. Cancer J. 2007 Mar-Apr13(2):78-9.
  • Peschel RE, Khan A, Colberg J, Wilson LD. The effect of age on prostate implantation results. Cancer J. 2006 Jul-Aug12(4):305-8.
  • Peschel RE. Prostate implant therapy: iodine-125 versus palladium-103. Cancer J. 2005 Sep-Oct11(5):383-4.

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