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Program Members

Co-Leaders

Pusztai, Lajos

Clinical Interests:breast cancer; cancer genetics.

  • Appt:(203) 200-2328

Members

Bale, Allen Everett

Research Interests:Molecular Mechanisms of Cancer; Predisposition and Developmental Defects; DNA Diagnostics; Birth Defects; Cancer; Fanconi; Genetics; Hedgehog; Multiple Endocrine Neoplasia; Patched; Skin Cancer; Tumor Suppressor

    Baserga, Susan J

    Research Interests:Ribosome biogenesis; RRNA processing; U3 RNP structure and function; RNA helicases; Polymerase I transcription and processing

      Bolognia, Jean L.

      Research Interests:Clinicopathologic correlations regarding various types of melanocytic nevi (moles) and melanoma; Cutaneous side effects of chemotherapy

      • Office:(203) 785-4092
      • Appt:(203) 789-1249

      Bosenberg, Marcus W.

      Research Interests:Melanocytic neoplasms; Soft tissue tumors; Cutaneous lymphoma; Genodermatoses

      • Office:(203) 737-3484
      • Appt:(203) 785-4094

      Braddock, Demetrios

      Research Interests:Structural biology; Hematopathology; Genitourinary Pathology

      • Office:(203) 737-1278
      • Lab:(203) 737-4277
      • Appt:(203) 785-6828

      Carling, Tobias

      Research Interests:Improved outcomes in minimally invasive endocrine surgery; Molecular genetics of endocrine tumors of the thyroid, parathyroid, adrenal (hyperaldosteronism, hypercortisolism, adrenal cancer, pheochromocytoma) and endocrine pancreas; Familial endocrine tumor susceptibility syndromes; Regulation of calcium homeostasis

      • Appt:(203) 737-2036

      Carrasco, Nancy

      • Office:(203) 785-4117

      Cooley, Lynn

      Research Interests:Molecular Genetics of Drosophila Oogenesis; Actin Cytoskeleton Regulation; Drosophila; Oogenesis; Ring Canal; Ovarian Muscle Function

      • Office:(203) 785-5067
      • Lab:(203) 785-2675

      Costa, Jose

      Research Interests:Oncology; Carcinogenesis; Tumor development and progression; Advanced diagnostics; Molecular diagnostics; Diagnosed genetic alterations in tumors; Cancer risk detection by mutational load distribution analysis

      • Office:(203) 785-5803
      • Appt:(203) 785-5803

      Forget, Bernard G

      Research Interests:Molecular Genetics of Erythroid Cell Differentiation; Hematopoietic Stem Cell Biology

      • Office:(203) 785-7002
      • Lab:(203) 785-4154
      • Appt:(203) 785-4744

      Garen, Alan

      Research Interests:Development; Genetics; Medical Sciences; Molecular Biology

        Giraldez, Antonio J.

        Research Interests:Developmental Biology; Non-coding RNAs, Post-transcriptional regulation; microRNAs; Gene regulatory networks; Systems Biology; Zebrafish

        • Office:(203) 785-5423

        Gunel, Murat

        Research Interests:Molecular genetics and biology of brain aneurysms and cavernous malformations; Molecular genetics of brain development

        • Office:(203) 737-2096
        • Appt:(203) 737-2096

        Halaban, Ruth

        Research Interests:Genes controlling differentiation, proliferation, malignant transformation of melanocytes; Growth factors and receptor kinases; Signal transduction; Epigenetic modification and gene expression; Markers for melanoma, Next-Generation sequencing, mutations

        • Office:(203) 785-4352

        Halene, Stephanie

        Research Interests:Hematopoiesis; Myeloid differentiation; Leukemia; Myelodysplasia

        • Appt:(203) 200-4363

        Hofstatter, Erin Wysong

        • Appt:(203) 200-2328

        Hoh, Josephine

        Research Interests:Interactions among genes; Environmental exposures

        • Office:(203) 785-2738
        • Lab:(203) 737-6007

        Ivanova, Natalia B.

        Research Interests:Embryonic and somatic stem cells; Vertebrate development; Functional genomics; Systems biology

          Katz, Samuel G.

          • Appt:(203) 785-2757

          Khan, Sajid A

          Research Interests:Cancer; metastasis; oligometastasis; microRNA; gene expression profiling; microsatellite instability; clinical outcomes; surgical resection; surgical palliation; liver metastasis; pancreas; gastric cancer; gastrointestinal stromal tumors (GIST); early onset colorectal cancer; sarcoma

          • Office:(203) 737-7915
          • Appt:(203) 337-8507

          Kidd, Kenneth Kay

          Research Interests:Complex Human Disorders; Neuropsychiatric Disorders; Human Population ; Genetics; Human Evolution

          • Office:(203) 785-2654
          • Lab:(203) 785-2653

          Kidd, Mark Simon

          Research Interests:Gastrointestinal neuroendocrine cell function

          • Office:(203) 785-6032

          Kim, Tae Hoon

          Research Interests:Transcription Regulation; Transcription Elongation; Transcription Insulation; Functional Genomics; Cancer Genomics; Epigenomics

            Kluger, Yuval

            Research Interests:Signal processing and dimensional reduction of genome-wide data; Local and non-local genomic pattern recognition; Identification of cancer subclones with proliferation and invasion potential in heterogeneous cancer biopsies

              Konigsberg, William H

              Research Interests:Blood Coagulation; DNA Replication; Genetics; Proteins and Macromolecules

                Krause, Diane S

                Research Interests:Bone Marrow Transplantation; Stem Cells; Cell and Molecular Hematology; Leukemia

                • Office:(203) 737-1678

                Kupfer, Gary

                Research Interests:Genomic instability; Development of cancer; Genetic syndrome Fanconi anemia (FA); Viral protein enhancement of cancer therapeutics

                • Office:(203) 785-4640
                • Appt:(203) 785-4640

                Lazova, Rossitza

                Research Interests:Spitz nevi; Spitzoid melanocytic neoplasms; Malignant melanoma; Melanocytic nevi on special anatomic sites

                • Office:(203) 785-4094
                • Appt:(203) 785-4094

                Leffell, David J.

                Research Interests:Molecular biology of basal cell carcinoma, squamous cell carcinoma; Wound healing; Skin cancer epidemiology

                • Office:(203) 785-7999
                • Appt:(203) 785-3466

                Lengyel, Peter

                Research Interests:p200 family proteins; mammalian differentiation; cell proliferation; interferons

                  Li, Peining

                  Research Interests:Cytogenetic and genomic analysis; Dissection of genetic mechanisms for growth regulation, mental development, and cancer progression

                  • Office:(203) 785-6317
                  • Appt:(203) 785-6317

                  Lifton, Richard P

                  Research Interests:Molecular genetics of common human diseases

                    Lin, Haifan

                    Research Interests:Stem cell RNA-mediated epigenetic programming, post-transcriptional regulation

                    • Office:(203) 785-6239
                    • Lab:(203) 785-6215

                    Lu, Jun

                    Research Interests:Non-coding RNAs in blood stem cell differentiation and malignancies; MicroRNA-mediated control of embryonic stem cell fates; MicroRNA mechanisms

                    • Office:(203) 737-3426

                    Mane, Shrikant M.

                    • Office:(203) 737-3104
                    • Lab:(203) 737-3058

                    Materin, Miguel A

                    Research Interests:Role of cytogenetics in ocular oncology for diagnosis and prognosis; Improving diagnostic and treatment methods for eye tumors

                    • Appt:(203) 785-2020

                    Matloff, Ellen T

                    Research Interests:BRCA1; BRCA2; HNPCC; Hereditary cancer; Genetic patents; Genetic counseling; Genetic testing; Sexuality and cancer; Providers of genetic counseling

                    • Office:(203) 764-8405
                    • Appt:(203) 764-8400

                    McGrath, James Michael

                    Research Interests:Developmental Genetics; Genetic Imprinting; Embryogenesis; Spermatogenesis

                    • Office:(203) 785-2686
                    • Appt:(203) 785-2660

                    Noonan, James

                    Research Interests:Human Evolution; Evolutionary Dynamics of Gene Regulation; Synthetic Biology; Applications of Ultra-High Throughput Sequencing Technologies; Comparative and Functional Genomics in Vertebrates

                      Pillai, Manoj

                      • Office:(203) 737-6403
                      • Lab:(203) 737-6990

                      Prasad, Manju

                      Research Interests:Endocrine, Head & Neck Pathology; Genotype-phenotype correlation in tumors; Protein expression and biomarkers in tumor tissues, and their diagnostic & prognostic relevance

                        Pusztai, Lajos

                        Research Interests:Breast cancer; Translational cancer research; Developing pharmacogenomic markers of response to breast cancer therapy and identifying methods to select the optimal treatment for each patient

                        • Appt:(203) 200-2328

                        Schwartz, Peter E

                        Research Interests:Ovarian Cancer; Uterine; Vaginal; Cervical and vulvar cancer; Screening for ovarian cancer

                        • Office:(203) 785-4014
                        • Appt:(203) 785-4014

                        Seli, Emre U

                        Research Interests:Translational regulation of gene expression during oocyte end early embryo development; Assessment of embryo viability in assisted reproductive technologies; Pathogenesis of endomentriosis.

                        • Office:(203) 785-7873
                        • Appt:(203) 785-4708

                        Shadel, Gerald S

                        Research Interests:Mitochondria; Mitochondrial Genetics and Biogenesis; Mitochondrial Dysfunction in Human Disease and Aging; Mechanisms of mtDNA Transcription and Mitochondrial Translation; Signaling Pathways that Sense and Control Mitochondrial Function; Cancer; Immune System Signaling

                          Sklar, Jeffrey L.

                          Research Interests:Molecular biology of human disease, especially cancer; Molecular biologic methods of disease diagnosis; Cancer-related genes and their functions in neoplasia and normal cellular physiology; Chromosomal structure and chromosomal abnormalities in genetic and neoplastic disorders; Immunogenetics

                          • Office:(203) 785-6836
                          • Appt:(203) 737-6012

                          Slack, Frank J

                          Research Interests:microRNA; aging; cancer biology; development; RNA; c. elegans

                            Strout, Matthew

                            Research Interests:Cancer genetics; Lymphomagenesis; Leukemogenesis; Immune diversification; Epigenetics; Tissue banking; Targeted therapy

                            • Office:(203) 785-7002
                            • Lab:(203) 737-6425
                            • Appt:(203) 200-4363

                            Taylor, Hugh S.

                            Research Interests:Homeobox genes; Embryo implantation; Endometriosis; Stem cells; Menopause; uterine Development; Endocrine disruption; Developmental programming

                            • Office:(203) 785-4001
                            • Appt:(203) 785-4708

                            Udelsman, Robert

                            Research Interests:Minimally invasive surgery; Including techniques for minimizing the trauma of surgery; Endocrine surgery; Endocrine oncology

                            • Office:(203) 785-2697
                            • Appt:(203) 785-2697

                            Weissman, Sherman Morton

                            Research Interests:Globin and Histocompatibility Gene Structure and Function; Genome wide mapping of gene activity and chromosome structure in man; Transcription Factors; Lymphocyte and myeloid Transcription Networks; Stem Cells; Cell Senescence; Methods for Molecular Genetics

                            • Office:(203) 737-2281

                            Xiao, Andrew Zhuo

                            Research Interests:Chromatin biology; Histone variants; Modifications and chromatin remodeling complexes; Cellular reprogramming (iPS) and stem cell biology; Mammalian neural crest cell; Mammalian DNA damage response

                            • Office:(203) 737-3650
                            • Lab:(203) 785-5111

                            Xu, Mina LuQing

                            Research Interests:Peripheral T-cell lymphoma, NOS; Classical hodgkin lymphoma; EBV-related lymphoproliferative disorders; Hemophagocytic lymphohistiocytosis; Hematopoietic stem cell niche

                            • Appt:(203) 785-3624

                            Xu, Tian

                            Research Interests:Genetic methodology; Cancer biology; Food and metabolism; Developmental mechanisms

                              Yan, Qin

                              Research Interests:Epigenetics; Gene regulation; Cancer biology; Stem cell biology

                              • Office:(203) 785-6672
                              • Lab:(203) 785-6496

                              Zhao, Hongyu

                              Research Interests:Statistical genomics; Computational biology; Genetic epidemiology; Genome wide association studies; Complex diseases; Risk prediction; High dimensional data; Dimension reduction; Network models; Graphical models; Bioinformatics; Next generation sequencing analysis; Cancer genomics; Epigenetics; Herbal medicine; Cicrobiome; Proteomics

                              • Office:(203) 785-3613