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Biospecimen, Pathology, and Genomics Core

The Biospecimen, Pathology, and Genomics Core for the Yale SPORE in Lung Cancer (YSILC) is the central repository of specimens necessary for the execution of the SPORE program. This Core focuses on tissue acquisition, processing, analysis and distribution to the internal projects of the YSILC as well as external investigators when there is adequate material to accommodate those requests. The collection of tissue from lung cancer specimens, including primary tumor biopsies and resections, biopsies of metastases and recurrences will all be facilitated by this Core. The Core will also coordinate blood and/or serum collection from these patients, as well as patients from whom no tissue is available, but whose blood is critical for studies related to treatment. In collaboration with the Biostatistics and Bioinformatics Core, this Core collects correlative clinical and biologic information to include with specimen distribution. Finally, the Core will provide tissue analysis services including quantitative measurements of protein, miRNA and mRNA as well as DNA genotyping and sequencing.

For investigators interested in requesting tissue specimens, please complete this request form and submit to:


  • Anthony N. Brady Professor of Pathology and Professor of Medicine (Medical Oncology); Director, Yale Cancer Center Tissue Microarray Facility, Pathology; Director, Yale Pathology Tissue Services, Pathology; Director, Physician Scientist Training Program, Pathology Research