Meet Dr. Stephanie Halene

Transcript

• 00:00I'm Stephanie Helena.
• 00:01I am associate professor of
• 00:03hematology and internal medicine.
• 00:05And I'm the chief of hematology,
• 00:08and I focus on Mallard display.
• 00:10JE and acute myeloid leukemia.
• 00:12To me, the most important thing is
• 00:15to build a team that seamlessly
• 00:17transitioned from the clinic all
• 00:20the way to basic science that
• 00:22brings questions from the clinic
• 00:24to the basic science laboratories,
• 00:27and that brings innovation from the basic
• 00:30science laboratories back to the patient.
• 00:32Advancements in in medicine.
• 00:34A general in hematology have been.
• 00:36Absolutely amazing and we are in a
• 00:39phenomenal time for for innovation.
• 00:41I think a lot of it comes from our
• 00:45deeper understanding of diseases.
• 00:47We have so many technologies at our
• 00:50fingertips to understand what causes disease,
• 00:53what drives disease,
• 00:54what results in resistance is to therapies,
• 00:57and as a result we can develop novel
• 01:01therapies that we never had the
• 01:03opportunity to do that are no longer these.
• 01:07Sledge hammer chemotherapies but very
• 01:09targeted at what drives the cancer.
• 01:12One area that my laboratory is
• 01:15particularly interested in is how
• 01:17RNA modifications and we look
• 01:20at how this RNA is altered,
• 01:22for example through mutations and so
• 01:25called splicing factors or through
• 01:28abnormalities and RNA editing.
• 01:30And we have identified a couple
• 01:33of mechanisms in that area that
• 01:35we may be able to exploit in the
• 01:38therapy of hematologic diseases.