Yale Cancer Center to Present Breakthrough Breast Cancer Research at International Conference in Texas

Yale Cancer Center (YCC) researchers at Yale School of Medicine will present the latest advances in breast cancer research at the 48th Annual San Antonio Breast Cancer Symposium (SABCS) at the Henry B. Gonzalez Convention Center next week.

As one of the largest and most prestigious breast cancer conferences, SABCS brings together over 10,000 attendees, including clinicians, researchers, patient advocates, and health care professionals from more than 100 countries. The symposium will spotlight cutting-edge advances in breast cancer treatment, diagnosis, and prevention. A scientific program will feature oral presentations, poster sessions, forums, and clinical case discussions.

YCC experts will present groundbreaking research on hormone replacement therapy in breast cancer care, innovative treatment options for HER2-positive and hormone receptor-positive breast cancers, and the impact of patient-centered approaches to care.

Tuesday, December 9, 2025

• Hormone Replacement Therapy (HRT) and Breast Cancer: How History Shaped Fear and What Comes Next—Re-examining Past Research, Debunking Myths, and Guiding Future Recommendations
  • Speaker: Maryam Lustberg, MD

Wednesday, December 10, 2025

• Patient-Reported Outcomes: Bridging the Gap Between Reporting and Reality
  • Presenter: Maryam Lustberg, MD
• RNA-based ESR1 and PGR Gene Expression Provides a Real-Time Readout of Hormone Receptor Status in Patients with Breast Cancer
  • Presenter: Lajos Pusztai, MD
• Translation Controversies:Antibody-Drug Conjugates (ADCs), Targeted Therapy, or Chemotherapy?
  • Speaker: David Rimm, MD, PhD

Thursday, December 11, 2025

• The Single-Arm Confirmatory Trial of Tamoxifen Alone Without Surgery for Low-Risk DCIS of the Breast (LORETTA Trial: JCOG1505)
  • Speaker:Eric Winer, MD
• Common and Rare Germline Variants Together with Somatic Mutations Alter the Integrity of Cancer Hallmark Regulatory Networks
  • Presenter: Jiawei Dai, PhD
• Repower: A Real-World Noninterventional Study of Outcomes and Experiences in Patients with HR+/HER2− Early Breast Cancer Treated with an Adjuvant CDK4/6 Inhibitor Plus Endocrine Therapy
  • Presenter: Maryam Lustberg, MD

Friday, December 12, 2025

• Beyond Cancer: Addressing Body Image, Hair Loss, and Skin Health After Treatment
  • Speaker: Tara Sanft, MD
• View from the Trenches: What to Do on Monday Morning
  • Presenter: Lajos Pusztai, MD, PhD

About Yale Cancer Center: Yale Cancer Center, a National Cancer Institute (NCI) designated comprehensive cancer center since 1974, is recognized for its groundbreaking research and innovative cancer treatment approaches. As the only NCI-designated comprehensive cancer center in Connecticut, YCC is dedicated to delivering excellence in patient care, research, and education. Through its partnership with Smilow Cancer Hospital, YCC continues to lead the way in advancing cancer research and offering hope to patients worldwide.

For the full list of Yale Cancer Center presentations at SABCS 2025, please see the attached document.