Joachim M Baehring, MD

Research Interests

Brain Neoplasms; Lymphoma; Medical Oncology; Neurology; Neurosurgery

Research Organizations

Neurology

Neurosurgery

Faculty Research

Yale Cancer Center: Developmental Therapeutics

Office of Cooperative Research

Research Summary

The primary foci of Dr. Baehring's laboratory work are primary brain tumors and neurological complications of cancer.

Dr. Baehring is involved in clinical and translational research at Yale University School of Medicine. He is an investigator on numerous therapeutic trials for patients with glioblastoma, lymphoma, and other brain tumors. Other research interests include the molecular pathogenesis and development of molecular markers for primary CNS lymphoma.

Specialized Terms: Molecular markers of cancer; Nervous system lymphoma

Selected Publications

• Evidence for antibody-mediated pathogenesis in anti-NMDAR encephalitis associated with ovarian teratoma

  Evidence for antibody-mediated pathogenesis in anti-NMDAR encephalitis associated with ovarian teratoma. Tüzün E, Zhou L, Baehring JM, Bannykh S, Rosenfeld MR, Dalmau J.Acta Neuropathol. 2009 Dec;118(6):737-43. doi: 10.1007/s00401-009-0582-4.

• Leukoencephalopathy in adults: Is it adrenoleukodystrophy? A case report and molecular analysis

  Leukoencephalopathy in adults: Is it adrenoleukodystrophy? A case report and molecular analysis. Dohle CI, Bannykh SI, Hisama FM, Baehring JM. J Neurol Sci. 2009 Jul 8.

• Unusual presentations of nervous system infection by Cryptococcus neoformans

  Unusual presentations of nervous system infection by Cryptococcus neoformans. Eric Searls D, Sico JJ, Bulent Omay S, Bannykh S, Kuohung V, Baehring J. Clin Neurol Neurosurg. 2009 Sep;111(7):638-42. Epub 2009 Jun 21.

• Anaplastic oligoastrocytoma in Turcot syndrome.

  Anaplastic oligoastrocytoma in Turcot syndrome. Baehring J, Hui P, Piepmeier J, Bannykh SI. J Neurooncol. 2009 Jun 4.

• A silver lining on the horizon for glioblastoma.

  A silver lining on the horizon for glioblastoma. Knisely JP, Baehring JM. Lancet Oncol. 2009 May;10(5):434-5.

Full List of PubMed Publications

• Kaulen LD, Baehring JM: Mirror Movements in a Patient With Brain Tumor. JAMA Neurol. 2018 Apr 1. PMID: 29435583
• Kaulen LD, Foss FM, Fulbright RK, Huttner A, Baehring JM: Neurolymphomatosis of the thoracic sympathetic chain. Neurology. 2017 Oct 31; 2017 Sep 22. PMID: 28939669
• Barbiero FJ, Huttner AJ, Judson BL, Baehring JM: Leiomyosarcoma of the infratemporal fossa with perineurial spread along the right mandibular nerve: a case report. CNS Oncol. 2017 Oct; 2017 Oct 9. PMID: 28990793
• Galluzzo D, Bulsara K, Fulbright RK, Baehring JM: Suspected retroorbital inflammation resulting in bilateral occlusion of the internal carotid arteries. J Neurol Sci. 2017 Sep 15; 2017 Jun 27. PMID: 28870588
• Vasquez JC, Huttner A, Zhang L, Marks A, Chan A, Baehring JM, Kahle KT, Dhodapkar KM: SOX2 immunity and tissue resident memory in children and young adults with glioma. J Neurooncol. 2017 Aug; 2017 Jun 15. PMID: 28620836
• Barbiero FJ, Baehring JM, Fulbright RK, Becker KP: MRI findings in Collet-Sicard syndrome. Neurology. 2017 Feb 21. PMID: 28220011
• Erson-Omay EZ, Henegariu O, Omay SB, Harmancı AS, Youngblood MW, Mishra-Gorur K, Li J, Özduman K, Carrión-Grant G, Clark VE, Çağlar C, Bakırcıoğlu M, Pamir MN, Tabar V, Vortmeyer AO, Bilguvar K, Yasuno K, DeAngelis LM, Baehring JM, Moliterno J, Günel M: Longitudinal analysis of treatment-induced genomic alterations in gliomas. Genome Med. 2017 Feb 2; 2017 Feb 2. PMID: 28153049
• Kann BH, Lester-Coll NH, Park HS, Yeboa DN, Kelly JR, Baehring JM, Becker KP, Yu JB, Bindra RS, Roberts KB: Adjuvant chemotherapy and overall survival in adult medulloblastoma. Neuro Oncol. 2017 Feb 1. PMID: 27540083
• Gauthier AC, Baehring JM: Hashimoto's encephalopathy mimicking Creutzfeldt-Jakob disease. J Clin Neurosci. 2017 Jan; 2016 Oct 13. PMID: 27743761
• Hahn LD, Fulbright R, Baehring JM: Hypertrophic pachymeningitis. J Neurol Sci. 2016 Aug 15; 2016 Jun 11. PMID: 27423604
• Schuster J, Lai RK, Recht LD, Reardon DA, Paleologos NA, Groves MD, Mrugala MM, Jensen R, Baehring JM, Sloan A, Archer GE, Bigner DD, Cruickshank S, Green JA, Keler T, Davis TA, Heimberger AB, Sampson JH: A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study. Neuro Oncol. 2015 Jun; 2015 Jan 13. PMID: 25586468
• Sheriff F, Narayanan NS, Huttner AJ, Baehring JM: Vogt-Koyanagi-Harada syndrome: A novel case and brief review of focal neurologic presentations. Neurol Neuroimmunol Neuroinflamm. 2014 Dec; 2014 Nov 20. PMID: 25419540
• Nygaard HB, Lippa CF, Mehdi D, Baehring JM: A Novel Presenilin 1 Mutation in Early-Onset Alzheimer's Disease With Prominent Frontal Features. Am J Alzheimers Dis Other Demen. 2014 Aug; 2014 Jan 24. PMID: 24463146
• Fu M, Patel T, Baehring JM, Bulsara KR: Cavernous carotid pseudoaneurysm following transsphenoidal surgery. J Neuroimaging. 2013 Jul; 2012 Jan 13. PMID: 22243969
• Christakis PG, Okin D, Huttner AJ, Baehring JM: Progressive multifocal leukoencephalopathy in an immunocompetent patient. J Neurol Sci. 2013 Mar 15; 2013 Feb 1. PMID: 23375959
• Clark VE, Erson-Omay EZ, Serin A, Yin J, Cotney J, Ozduman K, Avşar T, Li J, Murray PB, Henegariu O, Yilmaz S, Günel JM, Carrión-Grant G, Yilmaz B, Grady C, Tanrikulu B, Bakircioğlu M, Kaymakçalan H, Caglayan AO, Sencar L, Ceyhun E, Atik AF, Bayri Y, Bai H, Kolb LE, Hebert RM, Omay SB, Mishra-Gorur K, Choi M, Overton JD, Holland EC, Mane S, State MW, Bilgüvar K, Baehring JM, Gutin PH, Piepmeier JM, Vortmeyer A, Brennan CW, Pamir MN, Kiliç T, Lifton RP, Noonan JP, Yasuno K, Günel M: Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO. Science. 2013 Mar 1; 2013 Jan 24. PMID: 23348505
• Baehring JM, Fulbright RK: Diffusion-weighted MRI in neuro-oncology. CNS Oncol. 2012 Nov. PMID: 25057865
• Baehring JM, Batchelor TT: Diagnosis and management of neurolymphomatosis. Cancer J. 2012 Sep-Oct. PMID: 23006953
• Li J, Lee JJ, Chu E, Baehring JM: Reversible leukoencephalopathy with stroke-like presentation in a patient with 5-dihydropyrimidine dehydrogenase deficiency treated with continuous 5-fluorouracil infusion. Clin Colorectal Cancer. 2012 Sep; 2012 Mar 10. PMID: 22410472
• Lacy J, Baehring JM: Central nervous system malignancies. Hematol Oncol Clin North Am. 2012 Aug. PMID: 22794292
• Anton K, Baehring JM, Mayer T: Glioblastoma multiforme: overview of current treatment and future perspectives. Hematol Oncol Clin North Am. 2012 Aug; 2012 May 11. PMID: 22794286
• Dohle C, Baehring JM: Multiple strokes and bilateral carotid dissections: a fulminant case of newly diagnosed Ehlers-Danlos syndrome type IV. J Neurol Sci. 2012 Jul 15; 2012 May 3. PMID: 22559935
• Baehring JM, Marks PW: Treatment-related myelodysplasia in patients with primary brain tumors. Neuro Oncol. 2012 May; 2012 Mar 29. PMID: 22459128
• Baehring JM: Glioblastoma multiforme--new approaches to therapy. Cancer J. 2012 Jan-Feb. PMID: 22290251
• Blondin NA, Huttner A, Baehring JM: Unilateral tongue atrophy and fasciculation. Arch Neurol. 2011 Nov. PMID: 22084136
• Pittock SJ, Parisi JE, McKeon A, Roemer SF, Lucchinetti CF, Tan KM, Keegan BM, Hunter SF, Duncan PR, Baehring JM, Matsumoto JY, Lennon VA: Paraneoplastic jaw dystonia and laryngospasm with antineuronal nuclear autoantibody type 2 (anti-Ri). Arch Neurol. 2010 Sep. PMID: 20837856
• Baehring JM, Cairncross JG: Separating the wheat from the chaff: the search for truly informative biomarkers. Neurology. 2010 Jun 8; 2010 May 5. PMID: 20445147
• Tüzün E, Zhou L, Baehring JM, Bannykh S, Rosenfeld MR, Dalmau J: Evidence for antibody-mediated pathogenesis in anti-NMDAR encephalitis associated with ovarian teratoma. Acta Neuropathol. 2009 Dec. PMID: 19680671
• Dohle CI, Bannykh SI, Hisama FM, Baehring JM: Leukoencephalopathy in adults: is it adrenoleukodystrophy? A case report and molecular analysis. J Neurol Sci. 2009 Oct 15; 2009 Jul 9. PMID: 19592040
• Avdievich NI, Pan JW, Baehring JM, Spencer DD, Hetherington HP: Short echo spectroscopic imaging of the human brain at 7T using transceiver arrays. Magn Reson Med. 2009 Jul. PMID: 19365851
• Knisely JP, Baehring JM: A silver lining on the horizon for glioblastoma. Lancet Oncol. 2009 May. PMID: 19410186
• Moliterno JA, Sood S, Zambrano E, Kim JH, Piepmeier JM, Baehring JM: Intracranial benign fibrous histiocytomas: a case report and review. J Neurooncol. 2009 Apr; 2008 Nov 22. PMID: 19030779
• Baehring JM, Hochberg EP, Raje N, Ulrickson M, Hochberg FH: Neurological manifestations of Waldenström macroglobulinemia. Nat Clin Pract Neurol. 2008 Oct; 2008 Sep 23. PMID: 18813229
• Baehring JM, Fulbright RK: Delayed leukoencephalopathy with stroke-like presentation in chemotherapy recipients. J Neurol Neurosurg Psychiatry. 2008 May; 2007 Aug 6. PMID: 17682013
• Baehring JM, Phipps M, Wollmann G: Rostral midbrain infarction producing isolated lateropulsion. Neurology. 2008 Feb 19. PMID: 18285541
• Baehring JM, Landry ML, Cooper D, Hui P, Bannykh S: CSF IgH gene rearrangement analysis in isolated post-transplant lymphoproliferative disorder of the central nervous system. J Neurooncol. 2008 Jan; 2007 Oct 2. PMID: 17909942
• Baehring JM: Cord compression caused by extramedullary hematopoiesis within the epidural space. J Neurooncol. 2008 Jan; 2007 Jul 17. PMID: 17634741
• Baehring JM, Vives K, Bannykh S: Progressive multifocal leukoencephalopathy in a patient with marginal zone B-cell lymphoma. J Neurooncol. 2007 Dec; 2007 Jul 17. PMID: 17634742
• Baehring JM, Vives K, Ogle E, Bannykh S: A cerebral teratoma in an unusual location. J Neurooncol. 2007 Nov; 2007 Jul 19. PMID: 17634857
• Baehring JM: Tram track sign. J Neurooncol. 2007 Oct; 2007 Jul 11. PMID: 17622487
• Baehring JM, Bi WL, Bannykh S, Piepmeier JM, Fulbright RK: Diffusion MRI in the early diagnosis of malignant glioma. J Neurooncol. 2007 Apr; 2006 Oct 7. PMID: 17029014
• Bannykh S, Baehring JM: Images in neuro-oncology: rapid development of osseous and chondrous metaplasia in recurrent anaplastic ependymoma. J Neurooncol. 2007 Feb; 2006 Oct 13. PMID: 17039399
• Dalmau J, Tüzün E, Wu HY, Masjuan J, Rossi JE, Voloschin A, Baehring JM, Shimazaki H, Koide R, King D, Mason W, Sansing LH, Dichter MA, Rosenfeld MR, Lynch DR: Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Ann Neurol. 2007 Jan. PMID: 17262855
• Hochberg FH, Baehring JM, Hochberg EP: Primary CNS lymphoma. Nat Clin Pract Neurol. 2007 Jan. PMID: 17205072
• Bi WL, Baehring JM, Lesser RL: Evolution of brain imaging abnormalities in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes. J Neuroophthalmol. 2006 Dec. PMID: 17204916
• Baehring JM, Hochberg FH, Betensky RA, Longtine J, Sklar J: Immunoglobulin gene rearrangement analysis in cerebrospinal fluid of patients with lymphoproliferative processes. J Neurol Sci. 2006 Sep 25; 2006 Jun 9. PMID: 16764890
• Baehring JM, Vives KP, Bannykh S: Images in neuro-oncology: anaplastic pleomorphic xanthoastrocytoma. J Neurooncol. 2006 Sep; 2006 Jul 19. PMID: 16850109
• Baehring JM, Duncan C, Ogle E, Kim J: Images in neuro-oncology: choroid plexus carcinoma. J Neurooncol. 2006 Aug; 2006 Jun 23. PMID: 16794748
• Stern BV, Baehring JM, Kleopa KA, Hochberg FH: Multifocal motor neuropathy with conduction block associated with metastatic lymphoma of the nervous system. J Neurooncol. 2006 May. PMID: 16554970
• Baehring JM, Bannykh S: Chordoid glioma of the third ventricle. J Neurooncol. 2006 Feb. PMID: 16568345
• Bi WL, Bannykh SI, Martel M, Baehring JM: Paraneoplastic subacute sensory neuronopathy secondary to a malignant mixed mullerian tumor. Obstet Gynecol. 2006 Feb. PMID: 16449165
• Baehring JM, Hochberg FH: Primary lymphoma of the nervous system. Cancer J. 2006 Jan-Feb. PMID: 16613654
• Haykin ME, Gorman M, van Hoff J, Fulbright RK, Baehring JM: Diffusion-weighted MRI correlates of subacute methotrexate-related neurotoxicity. J Neurooncol. 2006 Jan. PMID: 16411025
• Bannykh S, Duncan C, Ogle E, Baehring JM: Atypical teratoid/rhabdoid tumor of the spinal canal. J Neurooncol. 2006 Jan. PMID: 16411024
• Baehring JM, Piepmeier J, Duncan C, Ogle E, Kim J, Liebsch N: Chondrosarcoma of the skull base. J Neurooncol. 2006 Jan. PMID: 16402277
• Haykin M, Gorman M, van Hoff J, Fulbright R, Baehring J: Diffusion-weighted MRI correlates of subacute methotrexate-related neurotoxicity. J Neurooncol. 2006 Jan. PMID: 16132495
• Baehring JM: An update on oligodendroglial neoplasms. Curr Opin Neurol. 2005 Dec. PMID: 16280674
• Baehring JM, de Lotbiniere A, Bannykh S: Heteronymous inferior quadrantanopsia from a hypothalamic metastasis. J Neurooncol. 2005 Dec. PMID: 16314960
• Baehring JM, Androudi S, Longtine JJ, Betensky RA, Sklar J, Foster CS, Hochberg FH: Analysis of clonal immunoglobulin heavy chain rearrangements in ocular lymphoma. Cancer. 2005 Aug 1. PMID: 15973665
• Baehring JM, Henchcliffe C, Ledezma CJ, Fulbright R, Hochberg FH: Intravascular lymphoma: magnetic resonance imaging correlates of disease dynamics within the central nervous system. J Neurol Neurosurg Psychiatry. 2005 Apr. PMID: 15774442
• Baehring JM, Biestek JS: Optic nerve head Drusen mimicking papilledema. J Neurooncol. 2005 Mar. PMID: 15803374
• Baehring JM: Neuro-oncology in a nutshell. J Neurooncol. 2005 Jan. PMID: 15719266
• Baehring JM, Dickey PS, Bannykh SI: Epithelioid hemangioendothelioma of the suprasellar area: a case report and review of the literature. Arch Pathol Lab Med. 2004 Nov. PMID: 15504067
• Baehring JM: Neuro-oncology in a nutshell. J Neurooncol. 2004 Nov. PMID: 15674485
• Bloch MH, Hwang WC, Baehring JM, Chambers SK: Paraneoplastic limbic encephalitis: ovarian cancer presenting as an amnesic syndrome. Obstet Gynecol. 2004 Nov. PMID: 15516442
• Baehring JM: Neuro-oncology in a nutshell. J Neurooncol. 2004 Oct. PMID: 15527100
• Piepmeier J, Baehring JM: Surgical resection for patients with benign primary brain tumors and low grade gliomas. J Neurooncol. 2004 Aug-Sep. PMID: 15527080
• Baehring JM: Neuro-oncology in a nutshell. J Neurooncol. 2004 Jun. PMID: 15218945
• Baehring JM: Neuro-oncology in a nutshell. J Neurooncol. 2004 May. PMID: 15164980
• Baehring JM: Neuro-oncology in a nutshell. J Neurooncol. 2004 Mar-Apr. PMID: 15072459
• Baehring JM: Images in neuro-oncology. Glioblastoma multiforme. J Neurooncol. 2004 Mar-Apr. PMID: 15072450
• Baehring JM: Neuro-oncology in a nutshell. J Neurooncol. 2004 Mar-Apr. PMID: 15072441
• Bannykh S, de Lotbinière A, Baehring JM: Images in neuro-oncology. J Neurooncol. 2004 Feb. PMID: 15015659
• Baehring JM: Neuro-oncology in a nutshell. J Neurooncol. 2004 Feb. PMID: 15015655
• Baehring JM, Bannykh S: Images in neuro-oncology. Hemangioblastoma. J Neurooncol. 2003 Nov. PMID: 14686731
• Baehring JM, Betensky RA, Batchelor TT: Malignant peripheral nerve sheath tumor: the clinical spectrum and outcome of treatment. Neurology. 2003 Sep 9. PMID: 12963767
• Baehring JM, Damek D, Martin EC, Betensky RA, Hochberg FH: Neurolymphomatosis. Neuro Oncol. 2003 Apr. PMID: 12672282
• Baehring JM, Longtine J, Hochberg FH: A new approach to the diagnosis and treatment of intravascular lymphoma. J Neurooncol. 2003 Feb. PMID: 12675317
• Baehring JM, Alemohammed S, Croul SE: Malignant fibrous histiocytoma presenting as an intraventricular mass five years after incidental detection of a mass lesion. J Neurooncol. 2001 Apr. PMID: 11508815

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