Liver Cancer Publications

Uhlig J, Sellers CM, Stein SM, Kim HS: Radiofrequency ablation versus surgical resection of hepatocellular carcinoma: contemporary treatment trends and outcomes from the United States National Cancer Database. Eur Radiol. 2019 May; 2018 Dec 17. PMID: 30560364

Torbenson MS, Arnold CA, Graham RP, Jain D, Kakar S, Lam-Himlin DM, Naini BV, Wu TT, Yeh M: Identification of key challenges in liver pathology: data from a multicenter study of extramural consults. Hum Pathol. 2019 May; 2019 Mar 8. PMID: 30857968

Saffo S, Taddei TH: Systemic Management for Advanced Hepatocellular Carcinoma: A Review of the Molecular Pathways of Carcinogenesis, Current and Emerging Therapies, and Novel Treatment Strategies. Dig Dis Sci. 2019 Apr. PMID: 30887150

Njei B, Esserman D, Krishnan S, Ohl M, Tate JP, Hauser RG, Taddei T, Lim J, Justice AC: Regional and Rural-Urban Differences in the Use of Direct-acting Antiviral Agents for Hepatitis C Virus: The Veteran Birth Cohort. Med Care. 2019 Apr. PMID: 30807449

Cannito S, Milani C, Cappon A, Parola M, Strazzabosco M, Cadamuro M: Fibroinflammatory Liver Injuries as Preneoplastic Condition in Cholangiopathies. Int J Mol Sci. 2018 Dec 4; 2018 Dec 4. PMID: 30518128

Fu W, Merola J, Malinis M, Lacy J, Barbieri A, Liapakis AH, Mulligan DC, Yoo PS: Successful treatment of primary donor-derived human herpesvirus-8 infection and hepatic Kaposi Sarcoma in an adult liver transplant recipient. Transpl Infect Dis. 2018 Oct; 2018 Aug 23. PMID: 30014622

Ippolito D, Querques G, Okolicsanyi S, Talei Franzesi C, Pecorelli A, Lombardi S, Orsini E, Strazzabosco M, Sironi S: Dynamic contrast enhanced perfusion CT imaging: A diagnostic biomarker tool for survival prediction of tumour response to antiangiogenetic treatment in patients with advanced HCC lesions. Eur J Radiol. 2018 Sep; 2018 Jul 20. PMID: 30150052

Kaffe E, Fiorotto R, Pellegrino F, Mariotti V, Amenduni M, Cadamuro M, Fabris L, Strazzabosco M, Spirli C: β-Catenin and interleukin-1β-dependent chemokine (C-X-C motif) ligand 10 production drives progression of disease in a mouse model of congenital hepatic fibrosis. Hepatology. 2018 May; 2018 Mar 25. PMID: 29140564

Carbone M, Cristoferi L, Cortesi PA, Rota M, Ciaccio A, Okolicsanyi S, Gemma M, Scalone L, Cesana G, Fabris L, Colledan M, Fagiuoli S, Ideo G, Belli LS, Munari LM, Mantovani L, Strazzabosco M: Optimising the clinical strategy for autoimmune liver diseases: Principles of value-based medicine. Biochim Biophys Acta Mol Basis Dis. 2018 Apr; 2017 Aug 24. PMID: 28844954

Cadamuro M, Stecca T, Brivio S, Mariotti V, Fiorotto R, Spirli C, Strazzabosco M, Fabris L: The deleterious interplay between tumor epithelia and stroma in cholangiocarcinoma. Biochim Biophys Acta Mol Basis Dis. 2018 Apr; 2017 Jul 27. PMID: 28757170

Strazzabosco M, Fiorotto R, Cadamuro M, Spirli C, Mariotti V, Kaffe E, Scirpo R, Fabris L: Pathophysiologic implications of innate immunity and autoinflammation in the biliary epithelium. Biochim Biophys Acta Mol Basis Dis. 2018 Apr; 2017 Jul 25. PMID: 28754453

Mariotti V, Strazzabosco M, Fabris L, Calvisi DF: Animal models of biliary injury and altered bile acid metabolism. Biochim Biophys Acta Mol Basis Dis. 2018 Apr; 2017 Jul 11. PMID: 28709963

Manfredo Vieira S, Hiltensperger M, Kumar V, Zegarra-Ruiz D, Dehner C, Khan N, Costa FRC, Tiniakou E, Greiling T, Ruff W, Barbieri A, Kriegel C, Mehta SS, Knight JR, Jain D, Goodman AL, Kriegel MA: Translocation of a gut pathobiont drives autoimmunity in mice and humans. Science. 2018 Mar 9. PMID: 29590047

Vyas M, Jain D: A practical diagnostic approach to hepatic masses. Indian J Pathol Microbiol. 2018 Jan-Mar. PMID: 29567877

Torres-Landa S, Muñoz-Abraham AS, Fortune BE, Gurung A, Pollak J, Emre SH, Rodriguez-Davalos MI, Schilsky ML: De-novo hepatocellular carcinoma after pediatric living donor liver transplantation. World J Hepatol. 2017 Dec 28. PMID: 29359020

Belli LS, Duvoux C, Berenguer M, Berg T, Coilly A, Colle I, Fagiuoli S, Khoo S, Pageaux GP, Puoti M, Samuel D, Strazzabosco M: ELITA consensus statements on the use of DAAs in liver transplant candidates and recipients. J Hepatol. 2017 Sep; 2017 Mar 18. PMID: 28323126

Ruan HB, Ma Y, Torres S, Zhang B, Feriod C, Heck RM, Qian K, Fu M, Li X, Nathanson MH, Bennett AM, Nie Y, Ehrlich BE, Yang X: Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation. Genes Dev. 2017 Aug 15; 2017 Sep 13. PMID: 28903979

Fabris L, Spirli C, Cadamuro M, Fiorotto R, Strazzabosco M: Emerging concepts in biliary repair and fibrosis. Am J Physiol Gastrointest Liver Physiol. 2017 Aug 1; 2017 May 19. PMID: 28526690

Choe J, Merola J, Kulkarni S, Mulligan DC: Allograft transmission of hepatitis C during the window period: Weighing the new risks and costs in the era of donor shortage. Clin Transplant. 2017 Aug; 2017 Jun 23. PMID: 28643333

Butt AA, Ren Y, Lo Re V 3rd, Taddei TH, Kaplan DE: Comparing Child-Pugh, MELD, and FIB-4 to Predict Clinical Outcomes in Hepatitis C Virus-Infected Persons: Results From ERCHIVES. Clin Infect Dis. 2017 Jul 1. PMID: 28369305

Vilarinho S, Erson-Omay EZ, Mitchell-Richards K, Cha C, Nelson-Williams C, Harmancı AS, Yasuno K, Günel M, Taddei TH: Exome analysis of the evolutionary path of hepatocellular adenoma-carcinoma transition, vascular invasion and brain dissemination. J Hepatol. 2017 Jul; 2017 Mar 18. PMID: 28323122

Ciaccio A, Cortesi PA, Bellelli G, Rota M, Conti S, Okolicsanyi S, Rota M, Cesana G, Mantovani LG, Annoni G, Strazzabosco M: Direct-acting antivirals combination for elderly patients with chronic hepatitis C: A cost-effectiveness analysis. Liver Int. 2017 Jul; 2017 Mar 2. PMID: 27943549

Benedict M, Zhang X: Non-alcoholic fatty liver disease: An expanded review. World J Hepatol. 2017 Jun 8. PMID: 28652891

Ippolito D, Querques G, Okolicsanyi S, Franzesi CT, Strazzabosco M, Sironi S: Diagnostic value of dynamic contrast-enhanced CT with perfusion imaging in the quantitative assessment of tumor response to sorafenib in patients with advanced hepatocellular carcinoma: A feasibility study. Eur J Radiol. 2017 May; 2017 Feb 20. PMID: 28583645

Cadamuro M, Brivio S, Spirli C, Joplin RE, Strazzabosco M, Fabris L: Autocrine and Paracrine Mechanisms Promoting Chemoresistance in Cholangiocarcinoma. Int J Mol Sci. 2017 Jan 13; 2017 Jan 13. PMID: 28098760

De Carlis L, Di Sandro S, Centonze L, Lauterio A, Buscemi V, De Carlis R, Ferla F, Sguinzi R, Okolicsanyi S, Belli L, Strazzabosco M: Liver-allocation policies for patients affected by HCC in Europe. Curr Transplant Rep. 2016 Dec; 2016 Oct 7. PMID: 28473952

Vilarinho S, Sari S, Mazzacuva F, Bilgüvar K, Esendagli-Yilmaz G, Jain D, Akyol G, Dalgiç B, Günel M, Clayton PT, Lifton RP: ACOX2 deficiency: A disorder of bile acid synthesis with transaminase elevation, liver fibrosis, ataxia, and cognitive impairment. Proc Natl Acad Sci U S A. 2016 Oct 4; 2016 Sep 19. PMID: 27647924

Taddei TH, Lo Re V 3rd, Justice AC: HIV, Aging, and Viral Coinfections: Taking the Long View. Curr HIV/AIDS Rep. 2016 Oct. PMID: 27614654

Gentry SE, Hirose R, Mulligan D: Resolving Misconceptions About Liver Allocation and Redistricting Methodology. JAMA Surg. 2016 Oct 1. PMID: 27333440

Belli LS, Berenguer M, Cortesi PA, Strazzabosco M, Rockenschaub SR, Martini S, Morelli C, Donato F, Volpes R, Pageaux GP, Coilly A, Fagiuoli S, Amaddeo G, Perricone G, Vinaixa C, Berlakovich G, Facchetti R, Polak W, Muiesan P, Duvoux C, European Liver and Intestine Association (ELITA).: Delisting of liver transplant candidates with chronic hepatitis C after viral eradication: A European study. J Hepatol. 2016 Sep; 2016 May 17. PMID: 27212241

Cadamuro M, Spagnuolo G, Sambado L, Indraccolo S, Nardo G, Rosato A, Brivio S, Caslini C, Stecca T, Massani M, Bassi N, Novelli E, Spirli C, Fabris L, Strazzabosco M: Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma. Cancer Res. 2016 Aug 15; 2016 Jun 21. PMID: 27328733

Pahade JK, Juice D, Staib L, Israel G, Cornfeld D, Mitchell K, Weinreb J: Is there an added value of a hepatobiliary phase with gadoxetate disodium following conventional MRI with an extracellular gadolinium agent in a single imaging session for detection of primary hepatic malignancies? Abdom Radiol (NY). 2016 Jul. PMID: 26800701

Vyas M, Zhang X, Morrow JS, Jain D, Salem RR, West AB: Focal hepatic glycogenosis associated with metastatic insulinoma presenting as mass lesions. Pathol Res Pract. 2016 Jan; 2015 Nov 26. PMID: 26627264

Morton SD, Cadamuro M, Brivio S, Vismara M, Stecca T, Massani M, Bassi N, Furlanetto A, Joplin RE, Floreani A, Fabris L, Strazzabosco M: Leukemia inhibitory factor protects cholangiocarcinoma cells from drug-induced apoptosis via a PI3K/AKT-dependent Mcl-1 activation. Oncotarget. 2015 Sep 22. PMID: 26296968

Belli LS, Romagnoli R, Nardi A, Marianelli T, Donato F, Corradini SG, Iemmolo RM, Morelli C, Pasulo L, Rendina M, De Martin E, Ponziani FR, Volpes R, Strazzabosco M, Angelico M, Liver Match Investigators.: Recipient female gender is a risk factor for graft loss after liver transplantation for chronic hepatitis C: Evidence from the prospective Liver Match cohort. Dig Liver Dis. 2015 Aug; 2015 Apr 16. PMID: 26055490

Balakrishnan M, Garcia-Tsao G, Deng Y, Ciarleglio M, Jain D: Hepatic arteriolosclerosis: a small-vessel complication of diabetes and hypertension. Am J Surg Pathol. 2015 Jul. PMID: 25786083

Fonseca AL, Cha CH: Hepatocellular carcinoma: a comprehensive overview of surgical therapy. J Surg Oncol. 2014 Nov; 2014 Jun 4. PMID: 24894746

Brown C, Chen C, Cha C: Gastrohepatic fistula as a complication of laparoscopic radiofrequency liver ablation in a patient with intrahepatic cholangiocarcinoma. J Clin Gastroenterol. 2014 Jul. PMID: 24440942

Hahn LD, Emre SH, Israel GM: Radiographic features of potential donor livers that precluded donation. AJR Am J Roentgenol. 2014 Apr. PMID: 24660732

Morell CM, Strazzabosco M: Notch signaling and new therapeutic options in liver disease. J Hepatol. 2014 Apr; 2013 Dec 3. PMID: 24308992

Fiorotto R, Raizner A, Morell CM, Torsello B, Scirpo R, Fabris L, Spirli C, Strazzabosco M: Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice. J Hepatol. 2013 Jul; 2013 Mar 7. PMID: 23500150

Huber S, Cornfeld D, Emre SH, Israel GM: Comparison of multidetector computed tomography angiography and cholangiography performed at 80 and 120 kVp in live liver donors. J Comput Assist Tomogr. 2013 May-Jun. PMID: 23674019

Lawrence DA, Oliva IB, Israel GM: Detection of hepatic steatosis on contrast-enhanced CT images: diagnostic accuracy of identification of areas of presumed focal fatty sparing. AJR Am J Roentgenol. 2012 Jul. PMID: 22733892

Strazzabosco M, Fabris L: Development of the bile ducts: essentials for the clinical hepatologist. J Hepatol. 2012 May; 2012 Jan 13. PMID: 22245898

Sethasine S, Jain D, Groszmann RJ, Garcia-Tsao G: Quantitative histological-hemodynamic correlations in cirrhosis. Hepatology. 2012 Apr. PMID: 22109744

Kulkarni S, Taddei TH: When should a hepatitis C-positive ESRD patient receive a renal transplant? Semin Dial. 2011 Jul-Aug; 2011 Jul 29. PMID: 21801216

Jain D, Ahrens W, Finkelstein S: Molecular evidence for the neoplastic potential of hepatic Von-Meyenburg complexes. Appl Immunohistochem Mol Morphol. 2010 Mar. PMID: 19770706

Hakim W, Sheikh S, Inayat I, Caldwell C, Smith D, Lorber M, Friedman A, Jain D, Bia M, Formica R, Mehal W: HCV response in patients with end stage renal disease treated with combination pegylated interferon alpha-2a and ribavirin. J Clin Gastroenterol. 2009 May-Jun. PMID: 19142165

Kamath A, Mehal W, Jain D: Colchicine-associated ring mitosis in liver biopsy and their clinical implications. J Clin Gastroenterol. 2008 Oct. PMID: 18391833

Iyer A, Robert ME, Bifulco CB, Salem RR, Jain D: Different cytokeratin and neuronal cell adhesion molecule staining patterns in focal nodular hyperplasia and hepatic adenoma and their significance. Hum Pathol. 2008 Sep; 2008 Jul 7. PMID: 18602664

Rogart JN, Iyer A, Robert ME, Levy G, Strazzabosco M: Type I autoimmune hepatitis presenting with acute liver failure in the setting of wild mushroom ingestion. J Clin Gastroenterol. 2008 Jul. PMID: 18496396

Carmack S, Taddei T, Robert ME, Mistry P, Jain D: Increased T-cell sinusoidal lymphocytosis in liver biopsies in patients with chronic hepatitis C and mixed cryoglobulinemia. Am J Gastroenterol. 2008 Mar; 2007 Oct 26. PMID: 17970837

Fiorotto R, Spirlì C, Fabris L, Cadamuro M, Okolicsanyi L, Strazzabosco M: Ursodeoxycholic acid stimulates cholangiocyte fluid secretion in mice via CFTR-dependent ATP secretion. Gastroenterology. 2007 Nov; 2007 Sep 2. PMID: 17983806

Minagawa N, Nagata J, Shibao K, Masyuk AI, Gomes DA, Rodrigues MA, Lesage G, Akiba Y, Kaunitz JD, Ehrlich BE, Larusso NF, Nathanson MH: Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile. Gastroenterology. 2007 Nov; 2007 Aug 14. PMID: 17916355

Neto AG, Dainiak C, Qin L, Salem RR, Jain D: Intraductal papillary cholangiocarcinoma associated with von Meyenberg complexes: a case report. Dig Dis Sci. 2007 Oct; 2007 Mar 30. PMID: 17394067

Marginean EC, Bennick M, Cyczk J, Robert ME, Jain D: Gastric siderosis: patterns and significance. Am J Surg Pathol. 2006 Apr. PMID: 16625099

Nagula S, Jain D, Groszmann RJ, Garcia-Tsao G: Histological-hemodynamic correlation in cirrhosis-a histological classification of the severity of cirrhosis. J Hepatol. 2006 Jan; 2005 Sep 23. PMID: 16274836

Sheela H, Seela S, Caldwell C, Boyer JL, Jain D: Liver biopsy: evolving role in the new millennium. J Clin Gastroenterol. 2005 Aug. PMID: 16000929

Hong-Curtis J, Yeh MM, Jain D, Lee JH: Rapid progression of autoimmune hepatitis in the background of primary sclerosing cholangitis. J Clin Gastroenterol. 2004 Nov-Dec. PMID: 15492611

Dranoff JA, Kruglov EA, Toure J, Braun N, Zimmermann H, Jain D, Knowles AF, Sévigny J: Ectonucleotidase NTPDase2 is selectively down-regulated in biliary cirrhosis. J Investig Med. 2004 Nov. PMID: 15651265

Jain D: Diagnosis of hepatocellular carcinoma: fine needle aspiration cytology or needle core biopsy. J Clin Gastroenterol. 2002 Nov-Dec. PMID: 12394213

Kruglov EA, Jain D, Dranoff JA: Isolation of primary rat liver fibroblasts. J Investig Med. 2002 May. PMID: 12033282

Jain D, Bowlus CL, Anderson JM, Robert ME: Granular cells as a marker of early amiodarone hepatotoxicity. J Clin Gastroenterol. 2000 Oct. PMID: 11034006

Garcia-Tsao G, Korzenik JR, Young L, Henderson KJ, Jain D, Byrd B, Pollak JS, White RI Jr: Liver disease in patients with hereditary hemorrhagic telangiectasia. N Engl J Med. 2000 Sep 28. PMID: 11006369

Jain D, Sarode VR, Abdul-Karim FW, Homer R, Robert ME: Evidence for the neoplastic transformation of Von-Meyenburg complexes. Am J Surg Pathol. 2000 Aug. PMID: 10935654