The pediatric program’s Director is Niketa Shah, MD, Assistant Professor of Pediatric Hematology and Oncology. At this time, the therapy is only FDA-approved for patients with childhood (up to age 25) acute lymphoblastic leukemia, the most common cancer in children, or adult B-cell non-Hodgkin’s lymphoma. However, researchers at Yale are conducting clinical trials to test new CAR T-cell therapies against other cancers, and Dr. Shah expects CAR T-cell therapies to be approved for a wider array of lymphomas and leukemias.
A large multidisciplinary team is involved in the care of patients receiving this therapy, including a transplant team, a cell collection and processing unit, the Intensive Care Unit, Pharmacy, Social Work, and access to our TeleHealth program for home evaluations. All patients are closely monitored for any side effects following therapy, and patients and families are given extensive education on how to safely continue care at home.