The Genitourinary Cancer Genetics and Prevention Program provides comprehensive risk assessment, education, screening, and treatment for patients with personal/family history of cancers involving urologic organs which includes the kidney, ureter, bladder, prostate, adrenal, or testicles. We also evaluate patients who are suspected of having an inherited risk of a disorder that could cause the future development of a particular cancer in the genitourinary tract. In these individuals we perform a risk assessment and develop a surveillance plan to enable early detection and treatment. Our multidisciplinary expert team of genetic counselors, nurse practitioners and physicians work together to create a personalized care plan for each patient. Patients identified with an increased risk of development of urologic cancers or confirmed to have a genetic cause of their cancer can be followed or have a treatment plan devised and discussed with their treating physicians.
Who is at Increased Risk of Developing a Cancer of the Genitourinary Tract?
Cancers of the Genitourinary tract are very common, accounting for approximately 20% of the total cancers diagnosed each year. Specific risk factors may predispose an individual to the development of cancer, but these vary by the type of cancer. Many of these risk factors are influenced by environmental and behavioral aspects and may be modifiable. A strong family history of cancers of the kidney, prostate, bladder, ureter, testicle, or adrenal glands are a major risk factor for development of cancer of the genitourinary tract. Many individuals may carry an inherited cancer gene that may significantly increase the risk of cancer development. These individuals are not inheriting cancer, but a strong risk of developing it, and may require close screening and early intervention. While most cancers are considered sporadic in nature, there is increasing recognition that between 1-10% of cancers are attributed to a strong hereditary predisposition. Specific attention is needed in individuals that present with cancer at a young age, bilateral disease (tumors on both sides of the body), other forms of cancers, and extensive family cancer history.
What to Expect During Your Visits
The Genitourinary Cancer Genetics and Prevention Program aims to provide a comprehensive, personalized consultation to meet the clinical needs and expectations of each patient. Prior to each visit the team will review available records including clinic notes, detailed family history, radiographic images, and pathology reports. Many patients will meet first with a genetic counselor who will review family history and other risk factors for cancer, explain the role of genetic testing for hereditary cancer syndromes, discuss the limitations and the implications of testing, and provide an overall cancer risk assessment. Patients with cancer or those with increased risk will have the opportunity to consult with a clinician well versed in hereditary forms of genitourinary malignancies. These visits will be to discuss the clinical aspects of their disease, unique aspects of hereditary forms of cancer, and specific diagnostic and treatment aspects based on the results of genetic testing. After the visit, the team will discuss the risk of specific conditions and devise an individualized testing strategy. Depending on a patient’s clinical needs, our program may invite specialists from Smilow Cancer Hospital, often national/international experts, to assist with management of associated conditions. You can expect world-class care by experts familiar with your condition.