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Pancreatic Cancer Early Detection Clinic

text for the pancreatic clinic brochure

The Pancreatic Cancer Early Detection Clinic provides comprehensive risk assessment, education, and screening for patients at increased risk of pancreas cancer. Our multidisciplinary expert team of genetic counselors, nurse practitioners, and physicians work together to create a personalized care plan for each patient. Patients with an increased risk can have a consultative visit at the Pancreas Cancer Early Detection Clinic by James Farrell, MBChB, and Susan Chmael, APRN.


Who is at Increased Risk of Pancreas Cancer


  • Strong family history of pancreatic cancer: 2 or more family members have a history of pancreatic cancer.
  • Genetic predisposition to pancreatic cancer: Inherited susceptibility secondary to BRCA1, BRCA2, ATM, PALB2, p16/CDKN2A (FAMMM Syndrome), Lynch Syndrome (HNPCC), and Peutz-Jeghers Syndrome (STK11).
  • Hereditary Pancreatitis: Chronic pancreatitis that occurs with genetic predispositions: PRSS1, PRSS2, CTRC, and SPINK1.

What to Expect from your Appointment

The Pancreatic Cancer Early Detection Clinic provides a comprehensive, personalized consultation tailored to the needs of the individual patient. Many patients will meet first with a genetic counselor who will review family history and other risk factors for cancer, explain the role of genetic testing for hereditary cancer syndromes, offer testing (if appropriate), and provide an overall cancer risk assessment. Those patients considered to be at increased risk of pancreas cancer can then choose to consult our Pancreatic Cancer Early Detection Clinic clinicians. We arrange for appropriate high-risk pancreas cancer screening, either clinically or as a part of a prospective research study [CAPS5 and PanFAM1]. If needed, we can also assist with arranging consultations with other specialists for a multidisciplinary approach to cancer prevention and surveillance.

Available High-Risk Pancreas Cancer Surveillance Studies

Multiple research screening studies for patients at increased risk of pancreatic cancer are available at Yale including CAPS5 and PanFAM1.

Clinic Hours and Location

Dr. James Farrell & Susan Chmael, APRN: Monday AM

The Smilow Cancer Genetics and Prevention Program
330 Orchard Street, Suite 107 New Haven, CT 06511
(203) 200-4362

For more information: Scott Merenda, BSN (203) 785-7019

Additional Information

We invite you to discover additional information that our clinical team incorporates in their assessment of overall risk of pancreas cancer.