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David C. Madoff, MD

Professor of Radiology & Biomedical Imaging and Medical and Surgical Oncology; Vice Chair for Clinical Research, Radiology & Biomedical Imaging; Section Chief, Interventional Radiology

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David C. Madoff, MD

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Dr. David C. Madoff is Professor of Radiology & Biomedical Imaging, Medical Oncology and Surgical Oncology at Yale School of Medicine. His current administrative roles are Vice Chair for Clinical Research and Section Chief of Interventional Radiology. Dr. Madoff earned his B.A. from Emory University and his M.D. from the University of Pittsburgh. He completed both his internship in Internal Medicine and residency in Radiology at SUNY at Stony Brook and his fellowship training in Vascular and Interventional Radiology at The University of Texas MD Anderson Cancer Center. Dr. Madoff achieved Board Certification in Diagnostic Radiology from the American Board of Radiology in 2000 and attained his Certificate of Added Qualifications in Vascular and Interventional Radiology in 2002. He was a faculty member in the Section of Interventional Radiology at MD Anderson Cancer Center in Houston, Texas for a decade before joining New York-Presbyterian Hospital/Weill Cornell Medical Center in 2011. While at Weill Cornell, Dr. Madoff served as Division Chief of Interventional Radiology from 2011 to 2015 and Vice Chair for Academic Affairs from 2015 to 2019. He moved to Yale in July, 2019.

Dr. Madoff has a strong background in clinical care and has treated many patients with complex oncological problems. His clinical interests are wide-ranging, and have included visceral vascular, hepatobiliary and genitourinary interventions, various embolotherapy and percutaneous biopsy techniques and many specialized therapies within the realm of Interventional Oncology. In particular, Dr. Madoff is world-renowned for his work on preoperative portal vein embolization, a technique used to improve the safety of major hepatic resection. This technique is based on the liver's ability to regenerate and has been used in patients with primary and metastatic hepatobiliary cancer to increase the size of the anticipated liver remnant before surgery. Without this procedure, many patients with potentially resectable disease would not be eligible for curative resection.

Dr. Madoff is a leader in academic Interventional Radiology and has been an invited speaker at numerous national and international meetings. He authored or co-authored over 200 peer-reviewed scientific articles, has written more than 30 book chapters and served as co-editor of four textbooks including Venous Embolization of the Liver: Radiologic and Surgical Practice (2011), Clinical Interventional Oncology (2014) and Interventional Radiology: Fundamentals of Clinical Practice (2019). Dr. Madoff served as Deputy Editor-in-Chief for the Journal of Vascular and Interventional Radiology from 2007 to 2010 and Deputy Editor for Radiology from 2012 to 2017. Dr. Madoff currently serves as founding co-Editor-in-Chief for Digestive Disease Interventions and on the editorial boards of additional publications that include Techniques in Vascular and Interventional Radiology, Seminars in Interventional Radiology, Cancer Biology & Medicine, Chinese Clinical Oncology and Current Oncology Reports. Dr. Madoff is active in many of the major radiological societies including the Radiological Society of North America, the American Roentgen Ray Society, the Society of Interventional Radiology and the Association of University Radiologists and serves on the Board of Trustees of the American Registry of Radiologic Technologists (ARRT). Based on his important contributions to the field, Dr. Madoff was elected Fellow of the Society of Interventional Radiology in 2007, the American College of Radiology in 2015 and the Cardiovascular and Interventional Radiology Society of Europe in 2018.

Education & Training

  • Fellow
    University of Texas at Houston; MD Anderson Cancer Center (2001)
  • Resident
    State University of New York at Stony Brook (2000)
  • MD
    University of Pittsburgh School of Medicine (1995)
  • BA
    Emory University (1989)

Honors & Recognition

AwardAwarding OrganizationDate
Connecticut Magazine Top Doctor (2021-2022)Castle Connolly2021
FellowCardiovascular and Interventional Radiology Society of Europe2018
Top Doctor New York Metro Area (2016 - 2022)Castle Connolly2016
FellowAmerican College of Radiology2015
Top Doctor (2015-2022)Castle Connolly2015
BMA Medical Book Award – Highly Commended in OncologyBritish Medical Association2014
BMA Medical Book Award – Highly Commended in RadiologyBritish Medical Association2012
FellowSociety of Interventional Radiology2007
Award for Excellence in ResearchUniversity of Pittsburgh School of Medicine1993
Psi Chi Psychology National Honor SocietyEmory University1989

Professional Service

National Comprehensive Cancer NetworkKidney Cancer Panel Member2020 - Present
Current Oncology ReportsInterventional Oncology Section Editor, Current Oncology Reports2019 - Present
Chinese Society of Clinical OncologyInterventional Oncology Section Editor, Chinese Clinical Oncology2019 - Present
American Registry for Radiologic TechnologistsBoard of Trustees2018 - Present
New York Roentgen Society, Interventional Radiology SectionBoard of Directors2018 - Present
European Society of RadiologyEditorial Board, European Radiology Experimental2017 - Present
Chinese Anti-Cancer AssociationEditorial Board, Cancer Biology and Medicine2017 - Present
American Society of Digestive Disease InterventionsCo-Editor-in-Chief, Digestive Disease Interventions2017 - Present
Radiological Society of North AmericaDeputy Editor, RADIOLOGY2012 - 2017
National Comprehensive Cancer NetworkHepatobiliary Cancers Panel2010 - 2011
Society of Interventional RadiologyDeputy Editor-in-Chief, Journal of Vascular and Interventional Radiology2007 - 2010

Departments & Organizations