2025
Common origins of autoimmune diseases and lymphoid malignancies
Leveille E, Müschen M. Common origins of autoimmune diseases and lymphoid malignancies. Trends In Immunology 2025 PMID: 40816970, PMCID: PMC12360480, DOI: 10.1016/j.it.2025.07.010.Peer-Reviewed Original ResearchLymphoid malignanciesAutoimmune diseasesRisk of lymphoma developmentDevelopment of autoimmune diseasesT-cell lymphomaDevelopment of lymphoid malignanciesMechanism of negative selectionAutoimmune manifestationsLymphoma developmentAutoreactive lymphocytesT cellsAutoimmune disordersAdaptive immunityMalignancyGenetic lesionsLymphocyte developmentPathological lymphocytesLymphocytesDisease typeDiseaseNegative selection
2018
Autoimmunity Checkpoints As Therapeutic Targets in B-Cell Malignancies
Chen Z, Muschen M. Autoimmunity Checkpoints As Therapeutic Targets in B-Cell Malignancies. Blood 2018, 132: 1587. DOI: 10.1182/blood-2018-99-113674.Peer-Reviewed Original ResearchAutoreactive B-cell antigen receptorsB-cell malignanciesAcute lymphoblastic leukemiaAutoreactive B cellsB cellsCell malignanciesB cell antigen receptorNormal B cellsTypes of cancerAIC activationTargeted therapyAutoreactive clonesMalignant transformationTargeted activationAutoreactive B lymphocytesLymphocyte developmentPI3KB-cell lymphomaB-lymphoid malignanciesB-cell receptor signalingDrug-resistant leukemiaB-cell leukemiaB-cell tumorsCell deathNegative selection
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