Voluntary Faculty
Voluntary Faculty are clinicians or other professionals who contribute significantly to Yale School of Medicine's educational programs but are not employed by the school.
Voluntary rank detailsMary Jane Minkin, MD
Clinical ProfessorAbout
Research
Publications
2025
"I did not recognize myself": a mixed methods study to better understand the experiences of menopause in a US workplace.
Mallen S, Coppola J, Shaffer N, Minkin M, Ward A, Snow S. "I did not recognize myself": a mixed methods study to better understand the experiences of menopause in a US workplace. Menopause The Journal Of The North American Menopause Society 2025 PMID: 40591541, DOI: 10.1097/gme.0000000000002575.Peer-Reviewed Original Research
2021
Weight gain in menopause: systematic review of adverse events in women treated with black cohosh
Naser B, Castelo-Branco C, Meden H, Minkin M, Rachoń D, Beer A, Pickartz S. Weight gain in menopause: systematic review of adverse events in women treated with black cohosh. Climacteric 2021, 25: 220-227. PMID: 34608830, DOI: 10.1080/13697137.2021.1973993.Peer-Reviewed Original ResearchConceptsAdverse eventsWeight gainSpontaneous adverse eventsBody fat compositionScientific evidencePopular treatment optionPostmenopausal womenMenopausal womenMenopausal symptomsTreatment optionsCase reportTreatment groupsSystematic reviewBlack cohoshFat compositionWeight changeWomenSignificant differencesFrequent problemPerimenopausalMenopauseReviewGroupSymptomsCases
2020
Review & meta-analysis: isopropanolic black cohosh extract iCR for menopausal symptoms – an update on the evidence
Castelo-Branco C, Gambacciani M, Cano A, Minkin M, Rachoń D, Ruan X, Beer A, Schnitker J, Henneicke-von Zepelin H, Pickartz S. Review & meta-analysis: isopropanolic black cohosh extract iCR for menopausal symptoms – an update on the evidence. Climacteric 2020, 24: 109-119. PMID: 33021111, DOI: 10.1080/13697137.2020.1820477.Peer-Reviewed Original ResearchConceptsClimacteric symptomsMenopausal symptomsBetter benefit-risk profileLow-dose transdermal estradiolICR/Evidence-based treatment optionsEstrogen-sensitive organsEstrogen-sensitive tissuesPsychological menopausal symptomsMinor adverse eventsBenefit-risk profileEvidence of hepatotoxicityGood safety profileStandardized mean differenceHormone-dependent diseasesSystematic literature searchTransdermal estradiolAdverse eventsGood tolerabilitySafety profileTreatment optionsSt. John's wortHerbal therapyHormone levelsClinical dataEffects of combined 17β-estradiol and progesterone on weight and blood pressure in postmenopausal women of the REPLENISH trial
Black D, Minkin M, Graham S, Bernick B, Mirkin S. Effects of combined 17β-estradiol and progesterone on weight and blood pressure in postmenopausal women of the REPLENISH trial. Menopause The Journal Of The North American Menopause Society 2020, 28: 32-39. PMID: 32932401, PMCID: PMC7769186, DOI: 10.1097/gme.0000000000001659.Peer-Reviewed Original ResearchConceptsE2/P4Diastolic blood pressureSystolic blood pressureBlood pressurePostmenopausal womenREPLENISH trialMonth 12Treatment-emergent adverse eventsWeight gainTwelve-month useHealthy postmenopausal womenSevere vasomotor symptomsBody mass indexAdverse eventsVasomotor symptomsMass indexEfficacy profileWomenBaselineHypertensionPlaceboUterusTrialsImportant changesPrevious findings
2019
The International Society for the Study of Women's Sexual Health Process of Care for the Identification of Sexual Concerns and Problems in Women
Parish S, Hahn S, Goldstein S, Giraldi A, Kingsberg S, Larkin L, Minkin M, Brown V, Christiansen K, Hartzell-Cushanick R, Kelly-Jones A, Rullo J, Sadovsky R, Faubion S. The International Society for the Study of Women's Sexual Health Process of Care for the Identification of Sexual Concerns and Problems in Women. Mayo Clinic Proceedings 2019, 94: 842-856. PMID: 30954288, DOI: 10.1016/j.mayocp.2019.01.009.Peer-Reviewed Original ResearchConceptsProcess of careFemale sexual dysfunctionSexual problemsSexual concernsSexual healthWomen's sexual healthPatient-centered communication skillsCaregivers of womenCommon sexual problemInternational expert panelInternational SocietySexual dysfunctionCommon disorderDistressing problemSexual painClinician expertiseSexual medicine specialistsMedicine specialistsClinical practicePatient needsClinical settingSexual medicineWomenExpert panelClinicians
2017
Sexuality, Sexual Dysfunction, and Menopause
Minkin M. Sexuality, Sexual Dysfunction, and Menopause. 2017, 165-171. DOI: 10.1007/978-3-319-42451-4_9.Peer-Reviewed Original ResearchVasomotor symptomsVulvovaginal atrophyLast menstrual periodPostmenopausal womenVaginal pHPhysical examinationMenstrual periodNew medicationsSexual dysfunctionLast examSexual healthSexual disinterestSexual activityMenopauseFemale ViagraSymptomsWomenSignificant changesYearsMedicationsPallorAtrophyDysfunctionTestosteroneVagina
2011
Suspected black cohosh hepatotoxicity
Naser B, Schnitker J, Minkin M, de Arriba S, Nolte K, Osmers R. Suspected black cohosh hepatotoxicity. Menopause The Journal Of The North American Menopause Society 2011, 18: 366-375. PMID: 21228727, DOI: 10.1097/gme.0b013e3181fcb2a6.Peer-Reviewed Original ResearchConceptsIsopropanolic black cohosh extractClinical trialsPostmenopausal womenLiver functionAlanine aminotransferaseAspartate aminotransferaseBlack cohoshPopular herbal treatmentPlacebo-controlled studyMonths of treatmentLiver function valuesStandardized mean differenceBlack cohosh extractMenopausal symptomsHerbal treatmentHepatotoxicity casesMean differenceAdverse effectsAminotransferaseTrialsWomenNonsignificant effectDescriptive statisticsMonthsΓ-glutamyltranspeptidase
2009
A Randomized Clinical Trial for Women With Vulvodynia: Cognitive-Behavioral Therapy vs. Supportive Psychotherapy
Masheb R, Kerns R, Lozano C, Minkin M, Richman S. A Randomized Clinical Trial for Women With Vulvodynia: Cognitive-Behavioral Therapy vs. Supportive Psychotherapy. Obstetrical & Gynecological Survey 2009, 64: 305-306. DOI: 10.1097/01.ogx.0000347335.07172.18.Peer-Reviewed Original ResearchCognitive behavioral therapyPain severityCBT groupSPT groupSupportive psychotherapyEmotional functionClinical trialsPhysician ratingsTreatment groupsTreatment of vulvodyniaChronic vulvar painPsychological interventionsGreater patient satisfactionSexual function outcomesEfficacy of CBTEffective psychosocial treatmentsOverall sexual functioningSelf-management approachSelf-management skillsSpecific behavioral interventionsPain outcomesVulvar painFunction outcomesPatient satisfactionSexual function
2006
Dr. Ruth on sex education for medical students
Minkin M. Dr. Ruth on sex education for medical students. Sexuality Reproduction And Menopause 2006, 4: 24-26. DOI: 10.1016/j.sram.2006.03.008.Peer-Reviewed Original Research
2004
Protect yourself from malpractice suits
Minkin M. Protect yourself from malpractice suits. Sexuality Reproduction And Menopause 2004, 2: 41-44. DOI: 10.1016/j.sram.2004.02.007.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
News
News
- November 17, 2025Source: Everyday Health
Hot Flash Treatment: Studies Identify 2 Unexpected Nondrug Remedies
- November 16, 2025Source: WMAQ-TV Online
Are your hormones imbalanced? Doctors explain how to know if you need testing
- November 12, 2025Source: Women's Health Online
These Are The Signs You Might Be Pregnant If You Have An IUD
- November 10, 2025Source: Women's Health Online
The FDA Just Announced A Major Update On Hormone Therapy In The U.S. Here's What It Means For You