Research & Publications
Working with the well known models of cutaneous immune hypersensitivity and immunity, Dr Askenase discovered the series of steps from challenge with antigen, in a sensitized host, to the entry of T cells into the site of challenge. This work uncovered a previously unrecognized roles of: B-1a B cells, NKT cells, IL-4, complement, serotonin and mast cells.These findings are relevant to the diagnosis and therapy of allergic and autoimmune diseases, as well as cancers and transplantation.
Current work in the Askenase lab centers on the very exciting newly discovered exosomes that are nanoparticles released by all cells sending RNA functional messages to each other. We work on these is models of allergy, multiple sclerosis, neurodegenerative diseases and stem cell therapies.
Education & Training
- MDYale University (1965)
- FellowNational Institutes of Health
- FellowYale University School of Medicine
- Allergies and ImmunologyFrance 2010Research on allergy, asthma and immunology
- Allergies and ImmunologyUnited Kingdom 2010Research on allergy and immunology