Suchitra Krishnan-Sarin, PhD
Albert E. Kent Professor of PsychiatryCards
Appointments
Additional Titles
Chair, Human Investigations Committee (IRB), Human Research Protections Program
Professor, Chronic Disease Epidemiology
Contact Info
Psychiatry
Connecticut Mental Health Center, 34 Park Street
New Haven, CT 06519
United States
Appointments
Additional Titles
Chair, Human Investigations Committee (IRB), Human Research Protections Program
Professor, Chronic Disease Epidemiology
Contact Info
Psychiatry
Connecticut Mental Health Center, 34 Park Street
New Haven, CT 06519
United States
Appointments
Additional Titles
Chair, Human Investigations Committee (IRB), Human Research Protections Program
Professor, Chronic Disease Epidemiology
Contact Info
Psychiatry
Connecticut Mental Health Center, 34 Park Street
New Haven, CT 06519
United States
About
Copy Link
Titles
Albert E. Kent Professor of Psychiatry
Chair, Human Investigations Committee (IRB), Human Research Protections Program; Professor, Chronic Disease Epidemiology
Biography
Dr. Suchitra Krishnan-Sarin is a Professor of Psychiatry at the Yale University School of Medicine. She is also a Chair of the Human Investigations Committee (IRB) at Yale. Her research is focused on developing a bio-behavioral understanding of substance use behaviors in adult and adolescent substance users, with the goal of developing optimal prevention and cessation interventions. In the area of adolescent tobacco use, her research focuses on understanding the appeal, abuse potential and patterns of use of tobacco products, developing and testing the use of novel behavioral and pharmacological cessation and prevention interventions, and understanding behavioral and neural predictors of use and cessation behaviors. She has contributed to the Surgeon General’s reports on youth tobacco use behaviors, served as a member of the FDA’s Tobacco Product Scientific Advisory Committee and currently serves on the CDC's Interagency Commission on Smoking and Health. Dr. Krishnan-Sarin is the Co-PI on the Yale Tobacco Centers Of Regulatory Science, funded by the NIH and FDA, which is using a multidisciplinary approach to understand the role of flavors and other constituents of tobacco products in tobacco and nicotine addiction. She also leads the ENACT initiative funded by the American Heart Association which is focused on developing interventions for e-cigarette use behaviors among youth. In a separate and distinct line of research Dr. Krishnan-Sarin also develops and tests novel pharmacological interventions for alcohol use disorders in adults and examines neurochemical predictors of alcohol use and treatment response.
Appointments
Psychiatry
ProfessorPrimaryChronic Disease Epidemiology
ProfessorSecondary
Other Departments & Organizations
- Cancer Prevention and Control
- Center for Nicotine and Tobacco Use Research at Yale (CENTURY)
- Center for the Translational Neuroscience of Alcohol
- Chronic Disease Epidemiology
- Connecticut Mental Health Center
- Division of Addictions
- Division of Women's Behavioral Health Research
- Neuroscience Research Training Program (NRTP)
- Psychiatry
- Psychology Section
- Psychotherapy Development Center
- Substance Abuse Research
- Yale Cancer Center
- Yale School of Public Health
- Yale Tobacco Center of Regulatory Science
- Yale Ventures
Education & Training
- Postdoctoral Fellow
- Yale Univeristy (1996)
- Postdoctoral fellowship
- Indiana University Purdue University at Indianapolis (1995)
- PhD
- Purdue University (1992)
Research
Copy Link
Overview
My research is focused on developing novel and effective treatments for substance use behaviors among youth and adults. Among youth, this work involves understanding the prevalence and bio-behavioral underpinnings of risk taking behaviors, using a developmental perspective, and behavioral and neuroimaging methods, and translating this information into optimal prevention and cessation intervention that use experimental, behavioral and pharmacological methods. While most of this work has focused on tobacco use behaviors, we have also extended these efforts to alcohol and marijuana use among youth. My research is also focused on developing empirical scientific evidence to support national and international tobacco regulatory efforts. Among adults, my work has focused using a translational approach to developing and evaluating medications to reduce alcohol drinking among heavy drinkers.
Medical Research Interests
ORCID
0000-0002-3272-9782
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Grace Kong, PhD
Meghan Morean, PhD
Krysten Bold, PhD
Dana Cavallo, PhD
Danielle Davis, PhD
Deepa Camenga, MD, MHS, FAAP
Smoking Cessation
Alcohol Drinking
Nicotine
Tobacco Use Disorder
Nicotiana
Substance-Related Disorders
Publications
2025
The Effect of “Ice” Components in Sweet-Flavored Nicotine-Containing E-Liquids Among Young Adult E-Cigarette Users
Li W, Davis D, Wu R, Gueorguieva R, Green B, Krishnan-Sarin S. The Effect of “Ice” Components in Sweet-Flavored Nicotine-Containing E-Liquids Among Young Adult E-Cigarette Users. Experimental And Clinical Psychopharmacology 2025, 33: 477-482. PMID: 40489161, DOI: 10.1037/pha0000786.Peer-Reviewed Original ResearchAltmetricConceptsWatermelon flavorRewarding effectsGeneral Labeled Magnitude ScaleE-cigarette usersEffects of flavorYoung adult e-cigarette usersFlavor likingHedonic scaleAdult e-cigarette usersLabeled Hedonic ScaleFlavorWatermelonDrug Effects QuestionnaireFlavor conditioningE-liquidsYoung adultsPast-month e-cigarette usersPropylene glycol/vegetable glycerinSensory effectsE-cigarettesFixed effectsNicotine e-liquidE-cigarette useLikingLaboratory sessionsCardiovascular Health Effects and Synthetic Cooling Agents in E-Cigarettes Labeled as "Clear" Marketed in Massachusetts After the Tobacco Product Flavoring Ban.
Minetti E, Erythropel H, Keith R, Davis D, Zimmerman J, Krishnan-Sarin S, Hamburg N. Cardiovascular Health Effects and Synthetic Cooling Agents in E-Cigarettes Labeled as "Clear" Marketed in Massachusetts After the Tobacco Product Flavoring Ban. Journal Of The American Heart Association 2025, 14: e036106. PMID: 40792641, DOI: 10.1161/jaha.124.036106.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsE-cigarettesE-cigarette usersBlood pressureTobacco productsFlavor banSynthetic cooling agentsFlavored tobacco productsNon-clearanceHeart rateCardiovascular health effectsE-cigarette useBaseline blood pressureE-liquidsElectronic cigarettesCardiovascular injuryE-cigarette productsHemodynamic effectsAcute useHealth impactsJUUL e-liquidsHeart rate measurementsMultivariate modelHemodynamic impactHealth effectsNonusersPutting the “Tobacco” in Tobacco-Free Blunt Wraps: Early Evidence From Adolescents Who Use Cannabis Blunts Signals a Potential Need for Regulatory Action
Morean M, Ponte V, Li W, Davis D, Sharma A, Krishnan-Sarin S, Bold K, Kong G. Putting the “Tobacco” in Tobacco-Free Blunt Wraps: Early Evidence From Adolescents Who Use Cannabis Blunts Signals a Potential Need for Regulatory Action. Nicotine & Tobacco Research 2025, ntaf139. PMID: 40600673, DOI: 10.1093/ntr/ntaf139.Peer-Reviewed Original ResearchAltmetricConceptsFood and Drug AdministrationTobacco productsDrug AdministrationNational survey studyBlunt useTobacco useUS Food and Drug AdministrationUnited States Food and Drug AdministrationStates Food and Drug AdministrationConnecticut high school studentsAssociated with negative outcomesCannabis dependenceNationally-representative sampleHigh school studentsCannabisTobacco-freeE-cigarettesStudy of AdolescentSchool-wideAnalytic sampleBivariate analysisNegative outcomesAdolescentsBluntBlunted signalingEffects of oral nicotine pouches on cigarette smoking behaviour and tobacco harm exposure: a randomised pilot trial in adults
Fucito L, Baldassarri S, Wu R, Gueorguieva R, Morean M, Herbst R, Krishnan-Sarin S, O’Malley S. Effects of oral nicotine pouches on cigarette smoking behaviour and tobacco harm exposure: a randomised pilot trial in adults. Tobacco Control 2025, tc-2024-059094. PMID: 40550628, PMCID: PMC12377922, DOI: 10.1136/tc-2024-059094.Peer-Reviewed Original ResearchAltmetricConceptsSmoking abstinenceOral nicotine pouchesSmoking behaviorNicotine pouchesRandomised pilot trialPoint prevalence smoking abstinenceComplete smoking abstinenceOutpatient research clinicCigarette smoking behaviorPreliminary supportTobacco-specific carcinogenNon-significantNicotineResearch clinicOpen-labelSmoking cessationAbstinenceCigarette substituteUrinary levelsWeek 4Nicotine strengthSmoking cigarettesParticipantsCompare groupsAdultsTobacco and cannabis co-use in young people: developing a collaborative research agenda to address an evolving problem
Ling P, Krishnan-Sarin S, Leventhal A, Pentz M. Tobacco and cannabis co-use in young people: developing a collaborative research agenda to address an evolving problem. Addictive Behaviors 2025, 170: 108402. PMID: 40541535, DOI: 10.1016/j.addbeh.2025.108402.Peer-Reviewed Original ResearchExamining E-cigarette Flavor Use and Preference by Menthol Cigarette Status and Quit Duration Among U.S. Adults Using E-cigarettes in a Smoking Cessation Attempt
Joseph M, Morean M, Wu R, Krishnan-Sarin S, O’Malley S, Bold K. Examining E-cigarette Flavor Use and Preference by Menthol Cigarette Status and Quit Duration Among U.S. Adults Using E-cigarettes in a Smoking Cessation Attempt. Nicotine & Tobacco Research 2025, 27: 1657-1661. PMID: 40056399, PMCID: PMC12370470, DOI: 10.1093/ntr/ntaf059.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSmoking menthol cigarettesSmoking cessation attemptsE-cigarettesE-cigarette flavorsMenthol cigarettesNon-menthol cigarettesQuit smokingCessation attemptsCross-sectional survey dataReduce cigarette useE-cigarette flavor preferenceDuration of abstinenceDuration of smoking abstinenceUS adultsCigarette typesQuit durationSmoking mentholSmoking abstinenceSurvey dataCigarette useGeneralized linear modelSmokingCigaretteNon-mentholAdultsUnderstanding Reasons to Quit or Reduce Vaping and Associations With Quitting Outcomes Among High School Adolescents in Connecticut
Bold K, Kong G, Morean M, Sharma A, Courtney W, Li W, Davis D, Camenga D, Ouellette R, Krishnan-Sarin S. Understanding Reasons to Quit or Reduce Vaping and Associations With Quitting Outcomes Among High School Adolescents in Connecticut. Journal Of Adolescent Health 2025, 77: 766-770. PMID: 39985534, PMCID: PMC12353269, DOI: 10.1016/j.jadohealth.2025.01.004.Peer-Reviewed Original ResearchAltmetricConceptsE-cigarette useQuit outcomesE-cigarettesReduce vapingAssociated with successful quittingNicotine/tobacco productsE-cigarette cessation interventionsPeer support strategiesLifetime e-cigarette useImprove public healthPunitive measuresE-cigarette accessE-cigarette interventionsCessation interventionsSuccessful quittingInfluence of friendsHigh school adolescentsSupport strategiesSchool adolescentsPublic healthInterventionVapingSurveyed high school studentsQuittingHealth“Ice” flavor elements in E-cigarette images: Influence on liking and intention to use among youth who are at risk of E-cigarette use
Li W, Davis D, Buta E, Gueorguieva R, Khan N, Green B, Garrison K, Krishnan-Sarin S. “Ice” flavor elements in E-cigarette images: Influence on liking and intention to use among youth who are at risk of E-cigarette use. Drug And Alcohol Dependence 2025, 269: 112600. PMID: 39970576, DOI: 10.1016/j.drugalcdep.2025.112600.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsT49 Effects of Nicotine Flux and Form on Speed and Total Amount of Arterial Blood Nicotine Delivery during Acute E-Cigarette Vaping
Baldassarri S, McKinney E, Mysirlidis S, Sharma M, Blohowiak R, Joseph P, Eid T, Nadim H, Hanna E, Karaoghlanian N, Adeniji A, Shihadeh A, Eissenberg T, Krishnan-Sarin S, O'Malley S, El-Hellani A, Talih S. T49 Effects of Nicotine Flux and Form on Speed and Total Amount of Arterial Blood Nicotine Delivery during Acute E-Cigarette Vaping. Drug And Alcohol Dependence 2025, 267: 111817. DOI: 10.1016/j.drugalcdep.2024.111817.Peer-Reviewed Original ResearchM51 The Influence of Flavor on Perception of Nicotine in E-Cigarettes
Davis D, Buta E, Gueorguieva R, Green B, Krishnan-Sarin S. M51 The Influence of Flavor on Perception of Nicotine in E-Cigarettes. Drug And Alcohol Dependence 2025, 267: 111645. DOI: 10.1016/j.drugalcdep.2024.111645.Peer-Reviewed Original Research
Clinical Trials
Current Trials
Varenicline for treatment of e-cigarette dependence
HIC ID2000032740RoleSub InvestigatorPrimary Completion Date09/30/2023Recruiting ParticipantsGenderBothAge18+ yearsA longitudinal study of the effects of cannabis exposure on neuro-development in adolescents and young adults
HIC ID2000024543RoleSub InvestigatorPrimary Completion Date01/31/2021Recruiting ParticipantsGenderBothAge13 years - 25 yearsImaging smoking-induced dopamine release utilizing PET imaging and nicotine patches
HIC ID2000023239RoleSub InvestigatorPrimary Completion Date05/31/2023Recruiting ParticipantsGenderBothAge18 years - 55 years
Academic Achievements & Community Involvement
Copy Link
Activities
activity Addiction
12/01/2015 - PresentProfessional OrganizationsEditorDetailsJournal Editorial Boardactivity Surgeon General’s Report “Preventing Tobacco Use Among Young People”.
2012 - PresentPublic ServiceAuthorDetailsHealth effects of smoking on children, adolescents, and young adultsactivity Institute of Medicine of the National Academies Report “Scientific Standards for Studies on Modified Risk Tobacco Products
2012 - PresentPublic ServiceAuthorDetailsEthics and Oversight of Research Studies on Modified Risk Tobacco Productsactivity Society for Research on Nicotine and Tobacco
03/01/2020 - PresentProfessional OrganizationsPresidentactivity DHHS Interagency committee on Smoking and Health, Center for Disease Control and Prevention
12/01/2019 - PresentPeer Review Groups and Grant Study SectionsAd-hoc Member
Honors
honor Young Investigator Award
01/01/1997National AwardSociety for Research on Nicotine and TobaccoDetailsUnited States
News & Links
Copy Link
News
- July 15, 2025Source: Parents (with Dr. Suchitra Krishnan-Sarin)
Nicotine Poisonings Among Kids Surge 763%, New Study Finds
- June 26, 2025Source: Tobacco Control
Effects of Oral Nicotine Pouches on Cigarette Smoking Behavior and Tobacco Harm Exposure: A Randomised Pilot Trial in Adults
- April 21, 2025
Yale Cancer Center Research Breakthroughs Unveiled at AACR Annual Meeting
- November 22, 2024
How Social Media Promotion of Vaping Targets Teens
Get In Touch
Copy Link
Contacts
Psychiatry
Connecticut Mental Health Center, 34 Park Street
New Haven, CT 06519
United States