Ya-Chi Ho

Ya-Chi Ho

MD, PhD, MMS
Assistant Professor of Microbial Pathogenesis and Medicine (Infectious Diseases); Investigator, HIV Reservoirs and Viral Eradication Transformative Science Group (Cure TSG)

Contact Information

Ya-Chi Ho, MD, PhD, MMS

Lab Location

  • Boyer Center for Molecular Medicine
    295 Congress Avenue, Rm BCMM 349
    New Haven, CT, 06510

Office Location

Ya-Chi Ho

Appointments

Biography

Dr. Ho takes a molecular virology approach to examine HIV persistence and develop HIV cure strategies. Using clinical samples from HIV-infected individuals, the Ho lab investigates host-HIV interactions with particular interests in HIV-1-host RNA landscape (using single-cell RNAseq), CD4 T cell expansion dynamics, HIV-host genome interactions, and HIV-1-specific silencing, and immune escape mechanisms. Dr. Ho was an infectious disease attending physician in Taiwan. She received her PhD (2013) and postdoctoral training at Johns Hopkins University School of Medicine in Dr. Robert F. Siliciano's lab. She was a tenure track instructor (2016) and then an assistant professor (2017) at Johns Hopkins School of Medicine before she joined Yale School of Medicine in September 2017. As a investigator of the AIDS Clinical Trial Group (ACTG) and the BEAT HIV Martin Delaney Collaboratory, she actively collaborate with geneticists, bioinformaticians, immunologists and physicians to study HIV-1 persistence. She is currently funded by an NIH R01 grant and an NIH R61/R33 grant as the Principal Investigator.

Education & Training

  • PhD
    Johns Hopkins University School of Medicine, Cellular and Molecular Medicine (2013)
  • MMS
    National Taiwan University, Clinical Medicine (2007)
  • MD
    National Cheng Kung University, Medicine (2002)
  • Postdoctoral fellow
    Johns Hopkins School of Medicine
  • Clinical fellow
    National Taiwan University Hospital
  • Resident
    National Taiwan University Hospital
  • Clinical clerkship
    Duke University Medical Center
  • Clinical clerkship
    Yale University

Activities

  • Oral presentation, Keystone Symposia: Functional Cures and the Eradication of HIV (X8)
    Whistler, Canada 2019
  • Invited Speaker, Conferences on Retroviruses and Opportunistic Infections (CROI)
    Seattle, United States 2019
  • Invited Speaker, Conferences on Retroviruses and Opportunistic Infections (CROI)
    Seattle, United States 2019
  • Invited Speaker, NIH Strategies for an HIV Cure
    Bethesda, United States 2018
  • Invited Speaker, NIH Strategies for an HIV Cure
    Bethesda, United States 2018
  • Invited Speaker, Academic Research Faculty Careers Workshop, Johns Hopkins University School of Medicine
    Baltimore, United States 2018
  • Invited Speaker, Academic Research Faculty Career Workshop, Johns Hopkins University School of Medicine
    Baltimore, United States 2018
  • Invited Speaker and session co-chair, AIDS 2018, The International AIDS Meeting
    Amsterdam, Netherlands 2018
  • Invited Speaker, AACR Special Conference on Cancer: Dormancy and Residual Disease
    Montreal, Canada 2018
  • Invited Speaker, University of Washington/Fred Hutchinson Center for AIDS Research Seminar
    Seattle, United States 2018
  • Invited Speaker, Keystone Symposia, HIV and Co-Infections
    Whistler, Canada 2018
  • Oral presentation, Conference on Retroviruses and Opportunistic Infections (CROI)
    Boston, United States 2018
  • Oral presentation, HIV Persistence During Therapy Workshop
    Miami, United States 2017
  • Invited Speaker, The International Meeting of the Institute of Human Virology
    Baltimore, United States 2017
  • Invited Speaker, Conference on Cell & Gene Therapy for HIV Cure
    Seattle, United States 2017
  • Invited Speaker, The Department of Microbiology, Immunology, and Tropical Medicine Seminar
    Washington, United States 2015

Honors & Recognition

AwardAwarding OrganizationDate
Andy Kaplan PrizeCold Spring Harbor Laboratory Meetings on Retroviruses2018
Gilead Sciences Research Scholar in HIVGilead Sciences2018
Rudolf J. Anderson FellowshipYale University2018
Lois E. and Franklin H. Top, Jr. Yale ScholarYale University School of Medicine2017
Distinguished Alumni AwardNational Cheng Kung University2016
W. W. Smith Charitable Foundation AIDS Research AwardW. W. Smith Charitable Foundation2016
Phi Beta KappaPhi Beta Kappa Honorary Society2014
Michael Shanoff Johns Hopkins Young Investigator AwardJohns Hopkins University School of Medicine2014
Young Investigator AwardCROI2013
Howard Hughes International Student Research FellowshipHoward Hughes Medical Institute2011
Best Teaching Resident AwardNational Taiwan University Hospital2007
Scholarship for PhD Studies AbroadMinistry of Education, Taiwan2007
Best Resident AwardDepartment of Medicine, National Taiwan University Hospital2003,2004
Phi Tau PhiPhi Tau Phi Honorary Society, Taiwan2002

Professional Service

OrganizationRoleDate
Keystone Symposia, Functional Cures and the Eradication of HIV (X8)Moderator2019
NIH Special Emphasis Panel Study SectionReviewer2019
CGT4HIV Cure Meeting 2019Committee Member2019 - Present
Conferences on Retroviruses and Opportunistic InfectionsReviewer2019
Conferences on Retroviruses and Opportunistic Infections (CROI)Reviewer2019
CGT4HIV Cure 2019Committee Member2019 - Present
American Foundation for AIDS Research (amfAR)Reviewer2018
NIH Special Emphasis Panel Study SectionReviewer2018
AIDS 2018, The International AIDS Society MeetingCo-Chair, "Poking, prodding and purging the final reservoir frontier" session2018
NIH, AIDS Immunology and Pathogenesis Study SectionReviewer2018
Ad hoc reviewer, Immunity, Science Translational Medicine, JCI, PNAS, Nature Communications, Cell Reports, Scientific Report, mBio, PLoS Pathogens, Retrovirology, Journal of Virology, Journal of Infectious DiseasesReviewer2018 - Present
Cold Spring Harbor Meetings on RetrovirusesPanelist and moderator, "HIV reservoirs and latency – What are they and how can we tackle them?"2018
Millennium Science InitiativeStudy section2018
Czech Science FoundationStudy section2017
Johns Hopkins University School of MedicineAssistant Professor of Medicine2017
NIH Special Emphasis Panel Study SectionAd hoc reviewer2016 - 2017
American Society for Microbiology Annual MeetingCo-convener, New Frontiers in HIV Cure session, American Society for Microbiology Annual Meeting (ASM Microbe), Boston, 20162016
DC CFAR Faculty Developmental Grant Study SectionAd hoc reviewer2016
Johns Hopkins University School of MedicineInstructor in Medicine2015 - 2017
Guest Editor, Journal of Virus EradicationGuest Editor, Journal of Virus Eradication2015
Johns Hopkins University School of MedicineResearch Associate2014 - 2015
American Society for MicrobiologyMember2011 - 2017

Departments & Organizations