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Gynecologic CRT

Objectives:

  • To build a multidisciplinary research program interacting with the research programs of Yale Cancer Center (YCC) and taking advantage of the shared YCC resources.
  • To develop a robust clinical/translational research program with high clinical trial accrual and impact on patient care.

Research Team Meetings: Monthly on Tuesday, 7:30am-8:30am

GYN Team Leader

  • Professor of Obstetrics, Gynecology, and Reproductive Sciences; Clinical Research Team Leader, Gynecologic Oncology, Yale Cancer Center; Co-Chief, Section of Gynecologic Oncology

    Dr. Alessandro D. Santin, a native of Italy, graduated with honors from the University of Brescia, Italy and received his postgraduate training in Obstetrics & Gynecology at the same University. He served a fellowship in Gynecologic Oncology at the University of California, Irvine and an International Fellowship in the Division of Gynecologic Oncology at the University of Arkansas for Medical Sciences, Little Rock, Arkansas. In 2000 he became a Clinical Assistant Professor and in 2004 an Associate Professor with Tenure in the same Division. Watch a video with Dr. Alessandro Santin >> Dr. Santin joined the faculty in the Section of Gynecologic Oncology in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale as Professor as of July 2008. He was the recipient of the American Association young investigator award and the Italian Society of Gynecologic Oncologists award for translational science. Dr. Santin has more than 300 original research and peer-reviewed publications including multiple review articles and book chapters and he has written extensively on various topics, including cancer of the ovary, endometrium and cervix as well as on tumor immunology and immunotherapy. Dr. Santin's clinical interests include cancer of the ovary, uterus, vagina, cervix and vulva; intraperitoneal chemotherapy, tumor genetics, immunology and immunotherapy; tumor angiogenesis, radiation biology and experimental therapeutics in Gynecologic Oncology. His current research interests include immunotherapy for ovarian, cervical and endometrial carcinomas refractory to standard treatment modalities; development of therapeutic vaccines against Human Papillomavirus (HPV) infected genital tumors, and the use of monoclonal antibodies against chemotherapy resistant gynecologic malignancies. Dr. Santin is a member of the Society of Gynecologic Oncologists, the Gynecologic Oncology Group, The International Gynecologic Oncology Society, the American Medical Association, the American Society of Immunologists, the Italian Society of Gynecologic Oncologists, the American Association for Cancer Research and the American Society of Clinical Oncology.

Members

  • Professor of Obstetrics, Gynecology and Reproductive Sciences; Director of Minimally Invasive and Robotic Surgery, Director of Minimally Invasive Gynecologic Surgery Fellowship

    Research Interests
    • Medical Oncology
    • Laparoscopy
    • Sarcoma, Endometrial Stromal
    • Cerclage, Cervical
    • Biomarkers, Pharmacological
    • Early Detection of Cancer
    • Fertility Preservation
    • Hereditary Breast and Ovarian Cancer Syndrome
  • Associate Professor of Obstetrics, Gynecology & Reproductive Sciences

    Research Interests
    • Genital Neoplasms, Female
    • Neoplasm Metastasis
    • Neoplasms, Hormone-Dependent
    • Ovarian Neoplasms
    • Pelvic Neoplasms
    • Uterine Neoplasms
    • Endometrial Neoplasms
    • Genomics
  • Sterling Professor of Immunobiology and Professor of Dermatology and of Molecular, Cellular, and Developmental Biology and of Epidemiology (Microbial Diseases); Investigator, Howard Hughes Medical Institute, (HHMI)

    Research Interests
    • Arboviruses
    • Autophagy
    • DNA Viruses
    • Herpes Simplex
    • Immune System
    • Immunity, Cellular
    • Immunity, Innate
    • Influenza, Human
    • Molecular Biology
    • Pneumonia, Viral
    • Pregnancy Complications
    • Proviruses
    • RNA Viruses
    • Sexually Transmitted Diseases
    • Tumor Virus Infections
    • Encephalitis, Viral
    • Central Nervous System Viral Diseases
    • Inflammasomes
  • Associate Professor of Pathology; Vice Chair of Operations and Director of Pathology Reference Services, Pathology; CLIA Laboratory Medical Director, Pathology; Affiliated Faculty, Yale Institute for Global Health

    Research Interests
    • Uterine Cervical Dysplasia
    • Pathology
    • Prognosis
    • Prostate
    • Global Health
    • Cancer Vaccines
    • Human papillomavirus 16
    • Early Detection of Cancer
    • Human Papillomavirus DNA Tests
    • Atypical Squamous Cells of the Cervix
    • Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18
    • Machine Learning
    • COVID-19
    • SARS-CoV-2
    • COVID-19 Vaccines
    • COVID-19 Testing
  • Professor of Obstetrics, Gynecology, and Reproductive Sciences; Clinical Research Team Leader, Gynecologic Oncology, Yale Cancer Center; Co-Chief, Section of Gynecologic Oncology

    Research Interests
    • Genital Neoplasms, Female
    • Gynecology
    • Immunotherapy
    • Neoplasms, Experimental
    • Ovarian Neoplasms
  • John Slade Ely Professor Emeritus of Obstetrics, Gynecology, and Reproductive Sciences; Vice Chair, Gynecology

    Research Interests
    • Uterine Cervical Neoplasms
    • Gynecology
    • Ovarian Neoplasms
    • Uterine Neoplasms
    • Vaginal Neoplasms
    • Vulvar Neoplasms
  • Associate Professor, Obstetrics, Gynecology and Reproductive Sciences; Affiliated Faculty, Yale Institute for Global Health; Director of Diversity, Equity, & Inclusion (DEI), Obstetrics, Gynecology & Reproductive Sciences; Associate Chief, Gynecologic Specialties; Director of Colposcopy and Cervical Dysplasia, Gynecologic Specialties

    Research Interests
    • Adolescent
    • Uterine Cervical Dysplasia
    • Contraception
    • Gynecology
    • Health Plan Implementation
    • HIV
    • Maternal Mortality
    • Mexico
    • Nepal
    • Obstetrics
    • Pregnancy
    • Global Health
    • Women's Health
    • Reproductive Medicine
    • Information Dissemination
    • Human papillomavirus 16
    • Papanicolaou Test