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Yale Cancer Center K12 Calabresi Immuno-Oncology Training Program (IOTP)

The Yale Cancer Center (YCC) K12 Calabresi Immuno-Oncology Training Program (IOTP) is a program funded by NCI to address the urgent need to train junior investigators to conduct patient-oriented cancer immunology and immunotherapy studies to accelerate the pace of these advances. IOTP trains both PhD and MD or MD/PhD junior faculty in clinically-relevant immuno-oncology and translational immunology. IOTP capitalizes on the wealth of expertise at Yale in immunobiology and immunotherapy. IOTP faculty have extensive track records of mentorship and are actively pursuing research in these areas. IOTP is supported by YCC and synergizes with the Yale Center for Clinical Investigation (YCCI), which provides some foundational courses. The training program includes didactic and practical training developed specifically for IOTP. The two-year curriculum includes courses on basic immunology and cancer immunology, immunotherapy-specific clinical trial design, the Cancer Immunology Forum and an individually tailored, two-year translational immuno-oncology research project encompassing both laboratory and clinical research. A panel of mentors including both a basic and clinical faculty member will be appointed for each Scholar (junior faculty.) Junior faculty within five years of appointment as faculty will be eligible to apply to IOTP, with up to five scholars appointed at any one time. Consistent with campus-wide efforts to encourage diversity, a Recruitment & Diversity Subcommittee is charged with maximizing diversity of the Scholar population. The program is led by an Executive Committee comprised of the PI (Dr. Harriet Kluger, YCC Associate Cancer Center Director for Education, Training, and Faculty Development) and two Co-Directors with complementary expertise (Drs. Akiko Iwasaki, and Alessandro Santin, Leader of the Gynecologic Oncology Research Team.) In summary, the IOTP draws upon an area of profound institutional strength and enable Yale Cancer Center to focus specifically on cross-disciplinary training of scholars in Cancer Immunotherapy, a field in great need of well-trained basic and clinical scientists to accommodate its explosive growth.

The two-year IOTP Scholar Award is open for application from August to December of each year and training starts on March 1st of the following year. Successful applicants are required to demonstrate a strong commitment to a career in cancer immunology. Recipients will be funded for up to 75% effort. Applicants are required to identify a mentor and a provide a research and mentorship proposal.

For additional information and questions, please contact: Meina Wang, PhD ( or Harriet Kluger, MD (





  • Akiko Iwasaki


    Waldemar Von Zedtwitz Professor of Immunobiology and Molecular, Cellular and Developmental Biology; Professor of Molecular Cellular and Developmental Biology; Investigator, Howard Hughes Medical Institute

  • Alessandro Santin


    Professor of Obstetrics, Gynecology, and Reproductive Sciences; Disease Aligned Research Team Leader, Gynecologic Oncology Program, Yale Cancer Center; Co-Chief, Section of Gynecologic Oncology

  • Harriet Kluger


    Professor of Medicine (Medical Oncology); Director, Yale SPORE in Skin Cancer, Yale Cancer Center; Director, , Yale Immuno-Oncology Training Program; Associate Cancer Center Director for Education, Training and Faculty Development, Yale Cancer Center; Deputy Section Chief, Medical Oncology

  • David F. Stern

    Chair, Curriculum Development and Training

    Professor of Pathology; Associate Cancer Center Director, Shared Resources, Yale Cancer Center; Co-Leader, Cancer Signaling Networks, Yale Cancer Center

  • Marcus Bosenberg

    Professor of Dermatology, Pathology, and Immunobiology; Co-Leader, Genetics, Genomics and Epigenetics, Yale Cancer Center; Interim Director, Yale Center for Immuno-Oncology; Director, Yale SPORE in Skin Cancer

  • Barbara Burtness

    Professor of Medicine (Medical Oncology); Disease Aligned Research Team Leader, Head and Neck Cancers Program; Co-Leader, Developmental Therapeutics, Yale Cancer Center

  • Lieping Chen

    United Technologies Corporation Professor in Cancer Research and Professor of Immunobiology, of Dermatology and of Medicine (Medical Oncology); Co-Leader, Cancer Immunology, Yale Cancer Center

  • Daniel DiMaio

    Waldemar Von Zedtwitz Professor of Genetics and Professor of Molecular Biophysics and Biochemistry and of Therapeutic Radiology; Deputy Director, Yale Cancer Center

  • Roy S. Herbst

    Ensign Professor of Medicine (Medical Oncology) and Professor of Pharmacology; Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital; Associate Cancer Center Director for Translational Research, Yale Cancer Center

  • Diane Krause

    Professor of Laboratory Medicine, of Cell Biology and of Pathology; Assoc. Director, Yale Stem Cell Center; Assoc. Director, Transfusion Medicine Service; Medical Director, Clinical Cell Processing Laboratory; Medical Director, Advanced Cell Therapy Laboratory