Signal Transduction Recent Publications

Brodehl A, Rezazadeh S, Williams T, Munsie NM, Liedtke D, Oh T, Ferrier R, Shen Y, Jones SJM, Stiegler AL, Boggon TJ, Duff HJ, Friedman JM, Gibson WT, FORGE Canada Consortium., Childs SJ, Gerull B: Mutations in ILK, encoding integrin-linked kinase, are associated with arrhythmogenic cardiomyopathy. Transl Res. 2019 Jun; 2019 Feb 15. PMID: 30802431

Beckmann JF, Bonneau M, Chen H, Hochstrasser M, Poinsot D, Merçot H, Weill M, Sicard M, Charlat S: Caution Does Not Preclude Predictive and Testable Models of Cytoplasmic Incompatibility: A Reply to Shropshire et al. Trends Genet. 2019 Jun; 2019 Apr 9. PMID: 30979535

Carvajal-Hausdorf DE, Patsenker J, Stanton KP, Villarroel-Espindola F, Esch A, Montgomery RR, Psyrri A, Kalogeras KT, Kotoula V, Foutzilas G, Schalper KA, Kluger Y, Rimm DL: Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T Cells in Trastuzumab-Treated Patients using Imaging Mass Cytometry. Clin Cancer Res. 2019 May 15; 2019 Feb 22. PMID: 30796036

Jeong J, Kim W, Hens J, Dann P, Schedin P, Friedman PA, Wysolmerski JJ: NHERF1 is Required for Localization of PMCA2 and Suppression of Early Involution in the Female Lactating Mammary Gland. Endocrinology. 2019 May 14; 2019 May 14. PMID: 31087002

Rothlin CV, Ghosh S: Serous macrophages pack Bhlhe40 for a randonnée. Nat Immunol. 2019 May 6; 2019 May 6. PMID: 31061527

Datar IJ, Sanmamed MF, Wang J, Henick BS, Choi J, Badri T, Dong W, Mani N, Toki MI, Mejías L, Lozano MD, Perez-Gracia JL, Velcheti V, Hellmann MD, Gainor JF, McEachern K, Jenkins D, Syrigos KN, Politi K, Gettinger S, Rimm DL, Herbst RS, Melero I, Chen L, Schalper KA: Expression analysis and significance of PD-1, LAG-3 and TIM-3 in human non-small cell lung cancer using spatially-resolved and multiparametric single-cell analysis. Clin Cancer Res. 2019 May 3; 2019 May 3. PMID: 31053602

Salgado R, Solit DB, Rimm DL, Bogaerts J, Canetta R, Lively T, Lyerly K, Span PN, Bateman-House A, Makady A, Bergmann L, Nagai S, Smith C, Robson M, Savage M, Voest E, Sweeney C, Lambin P, Thomas M, Harris L, Lacombe D, Massard C, IBCD-Faculty.: Addressing the dichotomy between individual and societal approaches to personalised medicine in oncology. Eur J Cancer. 2019 May 3; 2019 May 3. PMID: 31060925

Charkoftaki G, Thompson DC, Golla JP, Garcia-Milian R, Lam TT, Engel J, Vasiliou V: Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells. Chem Biol Interact. 2019 May 1; 2019 Mar 6. PMID: 30851239

Boggon TJ: ARGuing for a new kinase class. Nat Chem Biol. 2019 May. PMID: 30962625

Petrylak DP, Kantoff P, Vogelzang NJ, Mega A, Fleming MT, Stephenson JJ Jr, Frank R, Shore ND, Dreicer R, McClay EF, Berry WR, Agarwal M, DiPippo VA, Rotshteyn Y, Stambler N, Olson WC, Morris SA, Israel RJ: Phase 1 study of PSMA ADC, an antibody-drug conjugate targeting prostate-specific membrane antigen, in chemotherapy-refractory prostate cancer. Prostate. 2019 May; 2019 Jan 20. PMID: 30663074

Farasyn T, Crowe A, Hatley O, Neuhoff S, Alam K, Kanyo J, Lam T, Ding K, Yue W: Pre-incubation with everolimus and sirolimus reduces organic anion transporting polypeptide (OATP)1B1- and 1B3-mediated transport independently of mTOR kinase inhibition: implication in assessing OATP1B1- and OATP1B3-mediated drug-drug interactions. J Pharm Sci. 2019 Apr 29; 2019 Apr 29. PMID: 31047942

Trant AA, Szekely B, Mougalian SS, DiGiovanna MP, Sanft T, Hofstatter E, Silber A, Adelson KB, Chagpar A, Killelea B, Horowitz N, Lannin D, Park T, Corso M, Abraham G, Pollard-Murphy K, Sturrock T, Knill-Selby E, Western A, Servodidio C, Tasoulis MK, Healy B, Hatzis C, Pusztai L: The impact of communication style on patient satisfaction. Breast Cancer Res Treat. 2019 Apr 25; 2019 Apr 25. PMID: 31025271

Mazer BL, Homer RJ, Rimm DL: False-positive pathology: improving reproducibility with the next generation of pathologists. Lab Invest. 2019 Apr 24; 2019 Apr 24. PMID: 31019290

Wingrove E, Liu ZZ, Patel KD, Arnal-Estapé A, Cai WL, Melnick MA, Politi K, Monteiro C, Zhu L, Valiente M, Kluger HM, Chiang VL, Nguyen DX: Transcriptomic Hallmarks of Tumor Plasticity and Stromal Interactions in Brain Metastasis. Cell Rep. 2019 Apr 23. PMID: 31018140

Ren C, Yuan Q, Braun M, Zhang X, Petri B, Zhang J, Kim D, Guez-Haddad J, Xue W, Pan W, Fan R, Kubes P, Sun Z, Opatowsky Y, Polleux F, Karatekin E, Tang W, Wu D: Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment. Dev Cell. 2019 Apr 22; 2019 Mar 28. PMID: 30930167

Erdmann RS, Baguley SW, Richens JH, Wissner RF, Xi Z, Allgeyer ES, Zhong S, Thompson AD, Lowe N, Butler R, Bewersdorf J, Rothman JE, St Johnston D, Schepartz A, Toomre D: Labeling Strategies Matter for Super-Resolution Microscopy: A Comparison between HaloTags and SNAP-tags. Cell Chem Biol. 2019 Apr 18; 2019 Feb 7. PMID: 30745239

Barahona MJ, Baratta V, Ollodart J, Mulligan D, Geibel JP: Design and implementation of novel nutraceuticals and derivatives for treating intestinal disorders. Future Med Chem. 2019 Apr 17; 2019 Apr 17. PMID: 30994367

Kuzina ES, Ung PM, Mohanty J, Tome F, Choi J, Pardon E, Steyaert J, Lax I, Schlessinger A, Schlessinger J, Lee S: Structures of ligand-occupied β-Klotho complexes reveal a molecular mechanism underlying endocrine FGF specificity and activity. Proc Natl Acad Sci U S A. 2019 Apr 16; 2019 Apr 3. PMID: 30944224

Bentebibel SE, Hurwitz ME, Bernatchez C, Haymaker C, Hudgens CW, Kluger HM, Tetzlaff MT, Tagliaferri MA, Zalevsky J, Hoch U, Fanton C, Aung S, Hwu P, Curti BD, Tannir NM, Sznol M, Diab A: A First-in-Human Study and Biomarker Analysis of NKTR-214, a Novel IL2Rβγ-Biased Cytokine, in Patients with Advanced or Metastatic Solid Tumors. Cancer Discov. 2019 Apr 15; 2019 Apr 15. PMID: 30988166

Wong PF, Wei W, Smithy JW, Acs B, Toki MI, Blenman KRM, Zelterman D, Kluger HM, Rimm DL: Multiplex Quantitative Analysis of Tumor-Infiltrating Lymphocytes and Immunotherapy Outcome in Metastatic Melanoma. Clin Cancer Res. 2019 Apr 15; 2019 Jan 7. PMID: 30617133

Jordan EJ, Patil K, Suresh K, Park JH, Mosse YP, Lemmon MA, Radhakrishnan R: Computational algorithms for in silico profiling of activating mutations in cancer. Cell Mol Life Sci. 2019 Apr 13; 2019 Apr 13. PMID: 30982079

Chen Z, Chen JJ, Fan R: Single-Cell Protein Secretion Detection and Profiling. Annu Rev Anal Chem (Palo Alto Calif). 2019 Apr 12; 2019 Apr 12. PMID: 30978293

Hu X, Liu ZZ, Chen X, Schulz VP, Kumar A, Hartman AA, Weinstein J, Johnston JF, Rodriguez EC, Eastman AE, Cheng J, Min L, Zhong M, Carroll C, Gallagher PG, Lu J, Schwartz M, King MC, Krause DS, Guo S: MKL1-actin pathway restricts chromatin accessibility and prevents mature pluripotency activation. Nat Commun. 2019 Apr 12; 2019 Apr 12. PMID: 30979898

Zhao L, Pascual F, Bacudio L, Suchanek AL, Young PA, Li LO, Martin SA, Camporez JP, Perry RJ, Shulman GI, Klett EL, Coleman RA: Defective fatty acid oxidation in mice with muscle-specific acyl-CoA synthetase 1-deficiency increases amino acid use and impairs muscle function. J Biol Chem. 2019 Apr 11; 2019 Apr 11. PMID: 30975900

Moncur JT, Bartley AN, Bridge JA, Kamel-Reid S, Lazar AJ, Lindeman NI, Long TA, Merker JD, Rai AJ, Rimm DL, Rothberg PG, Vasalos P, Kim AS: Performance Comparison of Different Analytic Methods in Proficiency Testing for Mutations in the BRAF, EGFR, and KRAS Genes: A Study of the College of American Pathologists Molecular Oncology Committee. Arch Pathol Lab Med. 2019 Apr 10; 2019 Apr 10. PMID: 30969158

Wilson RS, Rauniyar N, Sakaue F, Lam TT, Williams KR, Nairn AC: Development of Targeted Mass Spectrometry-Based Approaches for Quantitation of Proteins Enriched in the Postsynaptic Density (PSD). Proteomes. 2019 Apr 2; 2019 Apr 2. PMID: 30986977

Yeh J, Lu M, Alvarez-Lugo L, Chai TC: Bladder urothelial BK channel activity is a critical mediator for innate immune response in urinary tract infection pathogenesis. Am J Physiol Renal Physiol. 2019 Apr 1; 2019 Jan 16. PMID: 30648906

Taylor CR, Jadhav AP, Gholap A, Kamble G, Huang J, Gown A, Doshi I, Rimm DL: A Multi-Institutional Study to Evaluate Automated Whole Slide Scoring of Immunohistochemistry for Assessment of Programmed Death-Ligand 1 (PD-L1) Expression in Non-Small Cell Lung Cancer. Appl Immunohistochem Mol Morphol. 2019 Apr. PMID: 30640753

Zhang C, Zhao Z, Sun Y, Xu L, JiaJue R, Cui L, Pang Q, Jiang Y, Li M, Wang O, He X, He S, Nie M, Xing X, Meng X, Zhou X, Yan L, Kaplan JM, Insogna KL, Xia W: Clinical and genetic analysis in a large Chinese cohort of patients with X-linked hypophosphatemia. Bone. 2019 Apr; 2019 Jan 23. PMID: 30682568

Xiang Q, Yang B, Li L, Qiu B, Qiu C, Gao XB, Zhou HJ, Min W: Critical role of Lin28-TNFR2 signalling in cardiac stem cell activation and differentiation. J Cell Mol Med. 2019 Apr; 2019 Feb 7. PMID: 30734494

Zou Y, Li S, Wu D, Xu Y, Wang S, Jiang Y, Liu F, Jiang Z, Qu H, Yu X, Wang X, Wang Y, Sun L: Resveratrol promotes trophoblast invasion in pre-eclampsia by inducing epithelial-mesenchymal transition. J Cell Mol Med. 2019 Apr; 2019 Feb 1. PMID: 30710417

Crawford ED, Koo PJ, Shore N, Slovin SF, Concepcion RS, Freedland SJ, Gomella LG, Karsh L, Keane TE, Maroni P, Penson D, Petrylak DP, Ross A, Mouraviev V, Reiter RE, Divgi C, Yu EY, RADAR III Group.: A Clinician's Guide to Next Generation Imaging in Patients With Advanced Prostate Cancer (RADAR III). J Urol. 2019 Apr. PMID: 30077557

Landau SI, Guo X, Velazquez H, Torres R, Olson E, Garcia-Milian R, Moeckel GW, Desir GV, Safirstein R: Regulated necrosis and failed repair in cisplatin-induced chronic kidney disease. Kidney Int. 2019 Apr. PMID: 30904067

Wang J, Sun J, Liu LN, Flies DB, Nie X, Toki M, Zhang J, Song C, Zarr M, Zhou X, Han X, Archer KA, O'Neill T, Herbst RS, Boto AN, Sanmamed MF, Langermann S, Rimm DL, Chen L: Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy. Nat Med. 2019 Apr; 2019 Mar 4. PMID: 30833750

Lu M, Zhu K, Schulam PG, Chai TC: A non-enzymatic method for dissection of mouse bladder urothelial tissue. Nat Protoc. 2019 Apr; 2019 Mar 20. PMID: 30894693

Roy SF, Dong D, Myung P, McNiff JM: Multinucleate cell angiohistiocytoma: A clinicopathologic study of 62 cases and proposed diagnostic criteria. J Cutan Pathol. 2019 Mar 29; 2019 Mar 29. PMID: 30927287

Wang N, Lu Y, Chen Z, Fan R: Multiplexed PCR-Free Detection of MicroRNAs in Single Cancer Cells Using a DNA-Barcoded Microtrough Array Chip. Micromachines (Basel). 2019 Mar 27; 2019 Mar 27. PMID: 30934734

Zhang X, Fan L, Wu J, Xu H, Leung WY, Fu K, Wu J, Liu K, Man K, Yang X, Han J, Ren J, Yu J: Macrophage p38α promotes nutritional steatohepatitis through M1 polarization. J Hepatol. 2019 Mar 23; 2019 Mar 23. PMID: 30914267

Mehnert M, Li W, Wu C, Salovska B, Liu Y: Combining Rapid Data Independent Acquisition and CRISPR Gene Deletion for Studying Potential Protein Functions: A Case of HMGN1. Proteomics. 2019 Mar 22; 2019 Mar 22. PMID: 30901150

Yang Y, Schneider PE, Culpitt T, Pavošević F, Hammes-Schiffer S: Molecular Vibrational Frequencies within the Nuclear-Electronic Orbital Framework. J Phys Chem Lett. 2019 Mar 21; 2019 Feb 28. PMID: 30776246

Miller CJ, Lou HJ, Simpson C, van de Kooij B, Ha BH, Fisher OS, Pirman NL, Boggon TJ, Rinehart J, Yaffe MB, Linding R, Turk BE: Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output. PLoS Biol. 2019 Mar; 2019 Mar 21. PMID: 30897078

Bidone TC, Polley A, Jin J, Driscoll T, Iwamoto DV, Calderwood DA, Schwartz MA, Voth GA: Coarse-Grained Simulation of Full-Length Integrin Activation. Biophys J. 2019 Mar 19; 2019 Feb 22. PMID: 30851876

Li X, Gong W, Wang H, Li T, Attri KS, Lewis RE, Kalil AC, Bhinderwala F, Powers R, Yin G, Herring LE, Asara JM, Lei YL, Yang X, Rodriguez DA, Yang M, Green DR, Singh PK, Wen H: O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3. Immunity. 2019 Mar 19; 2019 Feb 12. PMID: 30770249

Halaban R, Bacchiocchi A, Straub R, Cao J, Sznol M, Narayan D, Allam A, Krauthammer M, Mansour TS: A novel anti-melanoma SRC-family kinase inhibitor. Oncotarget. 2019 Mar 19; 2019 Mar 19. PMID: 31040916

Deng Y, Finck A, Fan R: Single-Cell Omics Analyses Enabled by Microchip Technologies. Annu Rev Biomed Eng. 2019 Mar 18; 2019 Mar 18. PMID: 30883211

Price NL, Rotllan N, Zhang X, Canfrán-Duque A, Nottoli T, Suarez Y, Fernández-Hernando C: Specific Disruption of Abca1 Targeting Largely Mimics the Effects of miR-33 Knockout on Macrophage Cholesterol Efflux and Atherosclerotic Plaque Development. Circ Res. 2019 Mar 15. PMID: 30707082

Safdar B, Guo X, Johnson C, D'Onofrio G, Dziura J, Sinusas AJ, Testani J, Rao V, Desir G: Elevated renalase levels in patients with acute coronary microvascular dysfunction - A possible biomarker for ischemia. Int J Cardiol. 2019 Mar 15; 2019 Jan 2. PMID: 30630613

Chen Z, Lu Y, Zhang K, Xiao Y, Lu J, Fan R: Multiplexed, Sequential Secretion Analysis of the Same Single Cells Reveals Distinct Effector Response Dynamics Dependent on the Initial Basal State. Adv Sci (Weinh). 2019 May 3; 2019 Mar 13. PMID: 31065513

Chen D, Xia S, Wang M, Lin R, Li Y, Mao H, Aguiar M, Famulare CA, Shih AH, Brennan CW, Gao X, Pan Y, Liu S, Fan J, Jin L, Song L, Zhou A, Mukherjee J, Pieper RO, Mishra A, Peng J, Arellano M, Blum WG, Lonial S, Boggon TJ, Levine RL, Chen J: Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer. Cancer Discov. 2019 Mar 12; 2019 Mar 12. PMID: 30862724

Mancini G, Pirruccio K, Yang X, Blüher M, Rodeheffer M, Horvath TL: Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight. Cell Rep. 2019 Mar 12. PMID: 30865877

Considine B, Hurwitz ME: Current Status and Future Directions of Immunotherapy in Renal Cell Carcinoma. Curr Oncol Rep. 2019 Mar 8; 2019 Mar 8. PMID: 30848378

Carvajal-Hausdorf D, Altan M, Velcheti V, Gettinger SN, Herbst RS, Rimm DL, Schalper KA: Expression and clinical significance of PD-L1, B7-H3, B7-H4 and TILs in human small cell lung Cancer (SCLC). J Immunother Cancer. 2019 Mar 8; 2019 Mar 8. PMID: 30850021

Altan M, Toki MI, Gettinger SN, Carvajal-Hausdorf DE, Zugazagoitia J, Sinard JH, Herbst RS, Rimm DL: Immune Checkpoint Inhibitor-Associated Pericarditis. J Thorac Oncol. 2019 Mar 7; 2019 Mar 7. PMID: 30851443

Katrancha SM, Shaw JE, Zhao AY, Myers SA, Cocco AR, Jeng AT, Zhu M, Pittenger C, Greer CA, Carr SA, Xiao X, Koleske AJ: Trio Haploinsufficiency Causes Neurodevelopmental Disease-Associated Deficits. Cell Rep. 2019 Mar 5. PMID: 30840899

Kim SY, Nair DM, Romero M, Serna VA, Koleske AJ, Woodruff TK, Kurita T: Transient inhibition of p53 homologs protects ovarian function from two distinct apoptotic pathways triggered by anticancer therapies. Cell Death Differ. 2019 Mar; 2018 Jul 9. PMID: 29988075

Doroshow DB, Sanmamed MF, Hastings K, Politi K, Rimm DL, Chen L, Melero I, Schalper KA, Herbst RS: Immunotherapy in Non-Small Cell Lung Cancer: Facts and Hopes. Clin Cancer Res. 2019 Mar 1; 2019 Mar 1. PMID: 30824587

Corredor G, Wang X, Zhou Y, Lu C, Fu P, Syrigos K, Rimm DL, Yang M, Romero E, Schalper KA, Velcheti V, Madabhushi A: Spatial Architecture and Arrangement of Tumor-Infiltrating Lymphocytes for Predicting Likelihood of Recurrence in Early-Stage Non-Small Cell Lung Cancer. Clin Cancer Res. 2019 Mar 1; 2018 Sep 10. PMID: 30201760

Shin MS, Yim K, Moon K, Park HJ, Mohanty S, Kim JW, Montgomery RR, Shaw AC, Krishnaswamy S, Kang I: Dissecting alterations in human CD8+ T cells with aging by high-dimensional single cell mass cytometry. Clin Immunol. 2019 Mar; 2019 Jan 16. PMID: 30659916

Min E, Schwartz MA: Translocating transcription factors in fluid shear stress-mediated vascular remodeling and disease. Exp Cell Res. 2019 Mar 1; 2019 Jan 8. PMID: 30633880

Nassar AF, Wisnewski AV, Wu T, Lam TT, King I: Development and Validation of LC-MS-MS Assay for the Determination of the Emerging Alkylating Agent Laromustine and Its Active Metabolite in Human Plasma. J Chromatogr Sci. 2019 Mar 1. PMID: 30395213

Liu Y, Mi Y, Mueller T, Kreibich S, Williams EG, Van Drogen A, Borel C, Frank M, Germain PL, Bludau I, Mehnert M, Seifert M, Emmenlauer M, Sorg I, Bezrukov F, Bena FS, Zhou H, Dehio C, Testa G, Saez-Rodriguez J, Antonarakis SE, Hardt WD, Aebersold R: Multi-omic measurements of heterogeneity in HeLa cells across laboratories. Nat Biotechnol. 2019 Mar; 2019 Feb 18. PMID: 30778230

Moro A, Driscoll TP, Boraas LC, Armero W, Kasper DM, Baeyens N, Jouy C, Mallikarjun V, Swift J, Ahn SJ, Lee D, Zhang J, Gu M, Gerstein M, Schwartz M, Nicoli S: MicroRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis. Nat Cell Biol. 2019 Mar; 2019 Feb 11. PMID: 30742093

de Kouchkovsky DA, Ghosh S, Rothlin CV: Induction of sterile type 2 inflammation. Nat Mater. 2019 Mar. PMID: 30783225

Madiraju AK, Qiu Y, Perry RJ, Rahimi Y, Zhang XM, Zhang D, Camporez JG, Cline GW, Butrico GM, Kemp BE, Casals G, Steinberg GR, Vatner DF, Petersen KF, Shulman GI: Author Correction: Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo. Nat Med. 2019 Mar. PMID: 30733621

Theodosakis N, Langdon CG, Micevic G, Krykbaeva I, Means RE, Stern DF, Bosenberg MW: Inhibition of isoprenylation synergizes with MAPK blockade to prevent growth in treatment-resistant melanoma, colorectal, and lung cancer. Pigment Cell Melanoma Res. 2019 Mar; 2018 Oct 22. PMID: 30281931

Kiapour AM, Sieker JT, Proffen BL, Lam TT, Fleming BC, Murray MM: Synovial fluid proteome changes in ACL injury-induced posttraumatic osteoarthritis: Proteomics analysis of porcine knee synovial fluid. PLoS One. 2019; 2019 Mar 1. PMID: 30822327

Beckmann JF, Bonneau M, Chen H, Hochstrasser M, Poinsot D, Merçot H, Weill M, Sicard M, Charlat S: The Toxin-Antidote Model of Cytoplasmic Incompatibility: Genetics and Evolutionary Implications. Trends Genet. 2019 Mar; 2019 Jan 23. PMID: 30685209

Wasko RR, Horsley V: Thin Skinned: Aged Adipocyte Atrophy Impacts Innate Immunity. Trends Immunol. 2019 Mar; 2019 Jan 31. PMID: 30713009

Martin DT, Ghabili K, Levi A, Humphrey PA, Sprenkle PC: Prostate Cancer Genomic Classifier Relates More Strongly to Gleason Grade Group Than Prostate Imaging Reporting and Data System Score in Multiparametric Prostate Magnetic Resonance Imaging-ultrasound Fusion Targeted Biopsies. Urology. 2019 Mar; 2018 Dec 12. PMID: 30552940

Zhang X, Price NL, Fernández-Hernando C: Non-coding RNAs in lipid metabolism. Vascul Pharmacol. 2019 Mar; 2018 Jun 19. PMID: 29929012

Aryal B, Suárez Y: Non-coding RNA regulation of endothelial and macrophage functions during atherosclerosis. Vascul Pharmacol. 2019 Mar; 2018 Mar 15. PMID: 29551552

Codina A, Renauer PA, Wang G, Chow RD, Park JJ, Ye H, Zhang K, Dong MB, Gassaway B, Ye L, Errami Y, Shen L, Chang A, Jain D, Herbst RS, Bosenberg M, Rinehart J, Fan R, Chen S: Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo. Cell Syst. 2019 Feb 27; 2019 Feb 20. PMID: 30797773

Yang F, Jin H, Que B, Chao Y, Zhang H, Ying X, Zhou Z, Yuan Z, Su J, Wu B, Zhang W, Qi D, Chen D, Min W, Lin S, Ji W: Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis. Oncogene. 2019 Feb 22; 2019 Feb 22. PMID: 30796352

Gupta R, Bugide S, Wang B, Green MR, Johnson DB, Wajapeyee N: Loss of BOP1 confers resistance to BRAF kinase inhibitors in melanoma by activating MAP kinase pathway. Proc Natl Acad Sci U S A. 2019 Feb 19; 2019 Feb 19. PMID: 30782837

Sharpe LJ, Howe V, Scott NA, Luu W, Phan L, Berk JM, Hochstrasser M, Brown AJ: Cholesterol increases protein levels of the E3 ligase MARCH6 and thereby stimulates protein degradation. J Biol Chem. 2019 Feb 15; 2018 Dec 13. PMID: 30545937

Kang D, Zhang H, Wang Z, Zhao T, Ginex T, Luque FJ, Yang Y, Wu G, Feng D, Wei F, Zhang J, De Clercq E, Pannecouque C, Chen CH, Lee KH, Murugan NA, Steitz TA, Zhan P, Liu X: Identification of Dihydrofuro[3,4- d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties. J Med Chem. 2019 Feb 14; 2019 Jan 18. PMID: 30624934

von Minckwitz G, Huang CS, Mano MS, Loibl S, Mamounas EP, Untch M, Wolmark N, Rastogi P, Schneeweiss A, Redondo A, Fischer HH, Jacot W, Conlin AK, Arce-Salinas C, Wapnir IL, Jackisch C, DiGiovanna MP, Fasching PA, Crown JP, Wülfing P, Shao Z, Rota Caremoli E, Wu H, Lam LH, Tesarowski D, Smitt M, Douthwaite H, Singel SM, Geyer CE Jr, KATHERINE Investigators.: Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer. N Engl J Med. 2019 Feb 14; 2018 Dec 5. PMID: 30516102

Xiao Y, Kim D, Dura B, Zhang K, Yan R, Li H, Han E, Ip J, Zou P, Liu J, Chen AT, Vortmeyer AO, Zhou J, Fan R: Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes. Adv Sci (Weinh). 2019 Apr 17; 2019 Feb 10. PMID: 31016107

Halabi S, Dutta S, Tangen CM, Rosenthal M, Petrylak DP, Thompson IM Jr, Chi KN, Araujo JC, Logothetis C, Quinn DI, Fizazi K, Morris MJ, Eisenberger MA, George DJ, De Bono JS, Higano CS, Tannock IF, Small EJ, Kelly WK: Overall Survival of Black and White Men With Metastatic Castration-Resistant Prostate Cancer Treated With Docetaxel. J Clin Oncol. 2019 Feb 10; 2018 Dec 21. PMID: 30576268

Piersigilli F, Lam TT, Vernocchi P, Quagliariello A, Putignani L, Aghai ZH, Bhandari V: Identification of new biomarkers of bronchopulmonary dysplasia using metabolomics. Metabolomics. 2019 Feb 2; 2019 Feb 2. PMID: 30830433

Yu F, Guo S, Li T, Ran J, Zhao W, Li D, Liu M, Yan X, Yang X, Zhu X, Zhou J: Ciliary defects caused by dysregulation of O-GlcNAc modification are associated with diabetic complications. Cell Res. 2019 Feb; 2018 Nov 14. PMID: 30429527

Franca A, Carlos Melo Lima Filho A, Guerra MT, Weerachayaphorn J, Loiola Dos Santos M, Njei B, Robert M, Xavier Lima C, Vieira Teixeira Vidigal P, Banales JM, Ananthanarayanam M, Leite MF, Nathanson MH: Effects of Endotoxin on Type 3 Inositol 1,4,5-Trisphosphate Receptor in Human Cholangiocytes. Hepatology. 2019 Feb; 2018 Dec 31. PMID: 30141207

Zhong S, Rivera-Molina F, Rivetta A, Toomre D, Santos-Sacchi J, Navaratnam D: Seeing the long tail: A novel green fluorescent protein, SiriusGFP, for ultra long timelapse imaging. J Neurosci Methods. 2019 Feb 1; 2018 Dec 19. PMID: 30578868

Martin DT, Shen H, Steinbach-Rankins JM, Zhu X, Johnson KK, Syed J, Saltzman WM, Weiss RM: Glycoprotein-130 Expression Is Associated with Aggressive Bladder Cancer and Is a Potential Therapeutic Target. Mol Cancer Ther. 2019 Feb; 2018 Oct 31. PMID: 30381445

Perry RJ, Rabin-Court A, Song JD, Cardone RL, Wang Y, Kibbey RG, Shulman GI: Dehydration and insulinopenia are necessary and sufficient for euglycemic ketoacidosis in SGLT2 inhibitor-treated rats. Nat Commun. 2019 Feb 1; 2019 Feb 1. PMID: 30710078

He S, Kahles F, Rattik S, Nairz M, McAlpine CS, Anzai A, Selgrade D, Fenn AM, Chan CT, Mindur JE, Valet C, Poller WC, Halle L, Rotllan N, Iwamoto Y, Wojtkiewicz GR, Weissleder R, Libby P, Fernández-Hernando C, Drucker DJ, Nahrendorf M, Swirski FK: Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease. Nature. 2019 Feb; 2019 Jan 30. PMID: 30700910

Speer KF, Sommer A, Tajer B, Mullins MC, Klein PS, Lemmon MA: Non-acylated Wnts Can Promote Signaling. Cell Rep. 2019 Jan 22. PMID: 30673610

Lay AJ, Coleman PR, Formaz-Preston A, Ting KK, Roediger B, Weninger W, Schwartz MA, Vadas MA, Gamble JR: ARHGAP18: A Flow-Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis. J Am Heart Assoc. 2019 Jan 22. PMID: 30630384

Jeong J, Choi J, Kim W, Dann P, Takyar F, Gefter JV, Friedman PA, Wysolmerski JJ: Inhibition of ezrin causes PKCα-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells. J Biol Chem. 2019 Jan 18; 2018 Nov 21. PMID: 30463939

Mis MA, Yang Y, Tanaka BS, Gomis-Perez C, Liu S, Dib-Hajj F, Adi T, Garcia-Milian R, Schulman BR, Dib-Hajj SD, Waxman SG: Resilience to Pain: A Peripheral Component Identified Using Induced Pluripotent Stem Cells and Dynamic Clamp. J Neurosci. 2019 Jan 16; 2018 Nov 20. PMID: 30459225

Zhou Y, Yang Y, Huang J, Jiang S, Du L: Advances in MERS-CoV Vaccines and Therapeutics Based on the Receptor-Binding Domain. Viruses. 2019 Jan 14; 2019 Jan 14. PMID: 30646569

Wang N, Zheng J, Chen Z, Liu Y, Dura B, Kwak M, Xavier-Ferrucio J, Lu YC, Zhang M, Roden C, Cheng J, Krause DS, Ding Y, Fan R, Lu J: Single-cell microRNA-mRNA co-sequencing reveals non-genetic heterogeneity and mechanisms of microRNA regulation. Nat Commun. 2019 Jan 9; 2019 Jan 9. PMID: 30626865

Li C, Bonazzoli E, Bellone S, Choi J, Dong W, Menderes G, Altwerger G, Han C, Manzano A, Bianchi A, Pettinella F, Manara P, Lopez S, Yadav G, Riccio F, Zammataro L, Zeybek B, Yang-Hartwich Y, Buza N, Hui P, Wong S, Ravaggi A, Bignotti E, Romani C, Todeschini P, Zanotti L, Zizioli V, Odicino F, Pecorelli S, Ardighieri L, Silasi DA, Litkouhi B, Ratner E, Azodi M, Huang GS, Schwartz PE, Lifton RP, Schlessinger J, Santin AD: Mutational landscape of primary, metastatic, and recurrent ovarian cancer reveals c-MYC gains as potential target for BET inhibitors. Proc Natl Acad Sci U S A. 2019 Jan 8; 2018 Dec 24. PMID: 30584090

Gupta K, Levinsohn J, Linderman G, Chen D, Sun TY, Dong D, Taketo MM, Bosenberg M, Kluger Y, Choate K, Myung P: Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis. Dev Cell. 2019 Jan 7; 2018 Dec 27. PMID: 30595533

Goedeke L, Perry RJ, Shulman GI: Emerging Pharmacological Targets for the Treatment of Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Type 2 Diabetes. Annu Rev Pharmacol Toxicol. 2019 Jan 6. PMID: 30625285

Breslow DK, Holland AJ: Mechanism and Regulation of Centriole and Cilium Biogenesis. Annu Rev Biochem. 2019 Jan 2; 2019 Jan 2. PMID: 30601682

Strauss J, Heery CR, Kim JW, Jochems C, Donahue RN, Montgomery AS, McMahon S, Lamping E, Marté JL, Madan RA, Bilusic M, Silver MR, Bertotti E, Schlom J, Gulley JL: First-in-Human Phase I Trial of a Tumor-Targeted Cytokine (NHS-IL12) in Subjects with Metastatic Solid Tumors. Clin Cancer Res. 2019 Jan 1; 2018 Aug 21. PMID: 30131389

Acs B, Pelekanou V, Bai Y, Martinez-Morilla S, Toki M, Leung SCY, Nielsen TO, Rimm DL: Ki67 reproducibility using digital image analysis: an inter-platform and inter-operator study. Lab Invest. 2019 Jan; 2018 Sep 4. PMID: 30181553

Hochstrasser M Editor: Preface. Methods Enzymol. 2019. PMID: 30910032

Hochstrasser M: Preface. Methods Enzymol. 2019. PMID: 30850064

Nagarajan A, Janostiak R, Wajapeyee N: Dot Blot Analysis for Measuring Global N6-Methyladenosine Modification of RNA. Methods Mol Biol. 2019. PMID: 30539562

Janostiak R, Wajapeyee N: RNA Modification Regulatory Genes in DNA Damage. Methods Mol Biol. 2019. PMID: 30539561

Rimm DL, Leung SCY, McShane LM, Bai Y, Bane AL, Bartlett JMS, Bayani J, Chang MC, Dean M, Denkert C, Enwere EK, Galderisi C, Gholap A, Hugh JC, Jadhav A, Kornaga EN, Laurinavicius A, Levenson R, Lima J, Miller K, Pantanowitz L, Piper T, Ruan J, Srinivasan M, Virk S, Wu Y, Yang H, Hayes DF, Nielsen TO, Dowsett M: An international multicenter study to evaluate reproducibility of automated scoring for assessment of Ki67 in breast cancer. Mod Pathol. 2019 Jan; 2018 Aug 24. PMID: 30143750

Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZS, Su X, Maganti A, Jiang C, Lu W, Zheng H, Bosenberg MW, Mehnert JM, Guo JY, Lattime E, Rabinowitz JD, White E: Author Correction: Autophagy maintains tumour growth through circulating arginine. Nature. 2019 Jan. PMID: 30523330

Jiang M, Xu B, Li X, Shang Y, Chu Y, Wang W, Chen D, Wu N, Hu S, Zhang S, Li M, Wu K, Yang X, Liang J, Nie Y, Fan D: O-GlcNAcylation promotes colorectal cancer metastasis via the miR-101-O-GlcNAc/EZH2 regulatory feedback circuit. Oncogene. 2019 Jan; 2018 Aug 9. PMID: 30093632

Torregrossa MM, MacDonald M, Stone KL, Lam TT, Nairn AC, Taylor JR: Phosphoproteomic analysis of cocaine memory extinction and reconsolidation in the nucleus accumbens. Psychopharmacology (Berl). 2019 Jan; 2018 Nov 8. PMID: 30411139

Merseburger AS, Apolo AB, Chowdhury S, Hahn NM, Galsky MD, Milowsky MI, Petrylak D, Powles T, Quinn DI, Rosenberg JE, Siefker-Radtke A, Sonpavde G, Sternberg CN: SIU-ICUD recommendations on bladder cancer: systemic therapy for metastatic bladder cancer. World J Urol. 2019 Jan; 2018 Sep 20. PMID: 30238401

Ryu HY, López-Giráldez F, Knight J, Hwang SS, Renner C, Kreft SG, Hochstrasser M: Distinct adaptive mechanisms drive recovery from aneuploidy caused by loss of the Ulp2 SUMO protease. Nat Commun. 2018 Dec 21; 2018 Dec 21. PMID: 30575729

Johnson DB, Nixon MJ, Wang Y, Wang DY, Castellanos E, Estrada MV, Ericsson-Gonzalez PI, Cote CH, Salgado R, Sanchez V, Dean PT, Opalenik SR, Schreeder DM, Rimm DL, Kim JY, Bordeaux J, Loi S, Horn L, Sanders ME, Ferrell PB Jr, Xu Y, Sosman JA, Davis RS, Balko JM: Tumor-specific MHC-II expression drives a unique pattern of resistance to immunotherapy via LAG-3/FCRL6 engagement. JCI Insight. 2018 Dec 20; 2018 Dec 20. PMID: 30568030

Insogna KL: Primary Hyperparathyroidism. N Engl J Med. 2018 Dec 20. PMID: 30575486

Rosowski KA, Boltyanskiy R, Xiang Y, Van den Dries K, Schwartz MA, Dufresne ER: Vinculin and the mechanical response of adherent fibroblasts to matrix deformation. Sci Rep. 2018 Dec 19; 2018 Dec 19. PMID: 30568231

Stiegler AL, Boggon TJ: PseudoGTPase domains in p190RhoGAP proteins: a mini-review. Biochem Soc Trans. 2018 Dec 17; 2018 Dec 4. PMID: 30514771

Pelekanou V, Villarroel-Espindola F, Schalper KA, Pusztai L, Rimm DL: CD68, CD163, and matrix metalloproteinase 9 (MMP-9) co-localization in breast tumor microenvironment predicts survival differently in ER-positive and -negative cancers. Breast Cancer Res. 2018 Dec 17; 2018 Dec 17. PMID: 30558648

Altan M, Kidwell KM, Pelekanou V, Carvajal-Hausdorf DE, Schalper KA, Toki MI, Thomas DG, Sabel MS, Hayes DF, Rimm DL: Association of B7-H4, PD-L1, and tumor infiltrating lymphocytes with outcomes in breast cancer. NPJ Breast Cancer. 2018; 2018 Dec 10. PMID: 30564631

Rodrigues MA, Gomes DA, Nathanson MH: Calcium Signaling in Cholangiocytes: Methods, Mechanisms, and Effects. Int J Mol Sci. 2018 Dec 6; 2018 Dec 6. PMID: 30563259

Waldt N, Seifert A, Demiray YE, Devroe E, Turk BE, Reichardt P, Mix C, Reinhold A, Freund C, Müller AJ, Schraven B, Stork O, Kliche S: Filamin A Phosphorylation at Serine 2152 by the Serine/Threonine Kinase Ndr2 Controls TCR-Induced LFA-1 Activation in T Cells. Front Immunol. 2018; 2018 Dec 4. PMID: 30568657

Hurwitz ME, Markowski P, Yao X, Deshpande H, Patel J, Mortazavi A, Donadio A, Stein MN, Kelly WK, Petrylak DP, Mehnert JM: Multicenter Phase 2 Trial of Gemcitabine, Carboplatin, and Sorafenib in Patients With Metastatic or Unresectable Transitional-Cell Carcinoma. Clin Genitourin Cancer. 2018 Dec; 2018 Jul 29. PMID: 30177237

Del Carmen S, Hapak SM, Ghosh S, Rothlin CV: Coagulopathies and inflammatory diseases: '…glimpse of a Snark'. Curr Opin Immunol. 2018 Dec; 2018 Sep 27. PMID: 30268838

Goedeke L, Bates J, Vatner DF, Perry RJ, Wang T, Ramirez R, Li L, Ellis MW, Zhang D, Wong KE, Beysen C, Cline GW, Ray AS, Shulman GI: Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents. Hepatology. 2018 Dec. PMID: 29790582

Siegel J, Totonchy M, Damsky W, Berk-Krauss J, Castiglione F Jr, Sznol M, Petrylak DP, Fischbach N, Goldberg SB, Decker RH, Stamatouli AM, Hafez N, Glusac EJ, Tomayko MM, Leventhal JS: Bullous disorders associated with anti-PD-1 and anti-PD-L1 therapy: A retrospective analysis evaluating the clinical and histopathologic features, frequency, and impact on cancer therapy. J Am Acad Dermatol. 2018 Dec; 2018 Jul 17. PMID: 30025829

Ko CJ, Myung P, Leffell DJ, Bourdon JC: Cutaneous immunohistochemical staining pattern of p53β isoforms. J Clin Pathol. 2018 Dec; 2018 Oct 10. PMID: 30305316

Toki MI, Mani N, Smithy JW, Liu Y, Altan M, Wasserman B, Tuktamyshov R, Schalper K, Syrigos KN, Rimm DL: Immune Marker Profiling and Programmed Death Ligand 1 Expression Across NSCLC Mutations. J Thorac Oncol. 2018 Dec; 2018 Sep 26. PMID: 30267840

Xin T, Gonzalez D, Rompolas P, Greco V: Flexible fate determination ensures robust differentiation in the hair follicle. Nat Cell Biol. 2018 Dec; 2018 Nov 12. PMID: 30420661

Li MD, Vera NB, Yang Y, Zhang B, Ni W, Ziso-Qejvanaj E, Ding S, Zhang K, Yin R, Wang S, Zhou X, Fang EX, Xu T, Erion DM, Yang X: Adipocyte OGT governs diet-induced hyperphagia and obesity. Nat Commun. 2018 Nov 30; 2018 Nov 30. PMID: 30504766

Marsh E, Gonzalez DG, Lathrop EA, Boucher J, Greco V: Positional Stability and Membrane Occupancy Define Skin Fibroblast Homeostasis In Vivo. Cell. 2018 Nov 29; 2018 Nov 8. PMID: 30415836

Cijsouw T, Ramsey AM, Lam TT, Carbone BE, Blanpied TA, Biederer T: Mapping the Proteome of the Synaptic Cleft through Proximity Labeling Reveals New Cleft Proteins. Proteomes. 2018 Nov 28; 2018 Nov 28. PMID: 30487426

Qin L, Min W, Xin S: AIP1 Suppresses Transplant Arteriosclerosis Through Inhibition of Vascular Smooth Muscle Cell Inflammatory Response to IFNγ. Anat Rec (Hoboken). 2018 Nov 24; 2018 Nov 24. PMID: 30471213

Jeschke GR, Lou HJ, Weise K, Hammond CI, Demonch M, Brennwald P, Turk BE: Substrate priming enhances phosphorylation by the budding yeast kinases Kin1 and Kin2. J Biol Chem. 2018 Nov 23; 2018 Oct 10. PMID: 30305396

Shook BA, Wasko RR, Rivera-Gonzalez GC, Salazar-Gatzimas E, López-Giráldez F, Dash BC, Muñoz-Rojas AR, Aultman KD, Zwick RK, Lei V, Arbiser JL, Miller-Jensen K, Clark DA, Hsia HC, Horsley V: Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair. Science. 2018 Nov 23. PMID: 30467144

Peng G, Wilson R, Tang Y, Lam TT, Nairn AC, Williams K, Zhao H: ProteomicsBrowser: MS/Proteomics Data Visualization and Investigation. Bioinformatics. 2018 Nov 21; 2018 Nov 21. PMID: 30462190

Lim CH, Sun Q, Ratti K, Lee SH, Zheng Y, Takeo M, Lee W, Rabbani P, Plikus MV, Cain JE, Wang DH, Watkins DN, Millar S, Taketo MM, Myung P, Cotsarelis G, Ito M: Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing. Nat Commun. 2018 Nov 21; 2018 Nov 21. PMID: 30464171

Dura B, Choi JY, Zhang K, Damsky W, Thakral D, Bosenberg M, Craft J, Fan R: scFTD-seq: freeze-thaw lysis based, portable approach toward highly distributed single-cell 3' mRNA profiling. Nucleic Acids Res. 2018 Nov 20; 2018 Nov 20. PMID: 30462277

Ernst AM, Syed SA, Zaki O, Bottanelli F, Zheng H, Hacke M, Xi Z, Rivera-Molina F, Graham M, Rebane AA, Björkholm P, Baddeley D, Toomre D, Pincet F, Rothman JE: S-Palmitoylation Sorts Membrane Cargo for Anterograde Transport in the Golgi. Dev Cell. 2018 Nov 19. PMID: 30458139

Zhang K, Lyu W, Yu J, Koleske AJ: Abl2 is recruited to ventral actin waves through cytoskeletal interactions to promote lamellipodium extension. Mol Biol Cell. 2018 Nov 15; 2018 Sep 26. PMID: 30256707

Stiegler AL, Boggon TJ: The N-Terminal GTPase Domain of p190RhoGAP Proteins Is a PseudoGTPase. Structure. 2018 Nov 6; 2018 Aug 30. PMID: 30174148

Goult BT, Yan J, Schwartz MA: Talin as a mechanosensitive signaling hub. J Cell Biol. 2018 Nov 5; 2018 Sep 25. PMID: 30254032

Barwari T, Eminaga S, Mayr U, Lu R, Armstrong PC, Chan MV, Sahraei M, Fernández-Fuertes M, Moreau T, Barallobre-Barreiro J, Lynch M, Yin X, Schulte C, Baig F, Pechlaner R, Langley SR, Zampetaki A, Santer P, Weger M, Plasenzotti R, Schosserer M, Grillari J, Kiechl S, Willeit J, Shah AM, Ghevaert C, Warner TD, Fernández-Hernando C, Suárez Y, Mayr M: Inhibition of profibrotic microRNA-21 affects platelets and their releasate. JCI Insight. 2018 Nov 2; 2018 Nov 2. PMID: 30385722

Trampert DC, Nathanson MH: Regulation of bile secretion by calcium signaling in health and disease. Biochim Biophys Acta Mol Cell Res. 2018 Nov; 2018 May 19. PMID: 29787781

Mesa KR, Kawaguchi K, Cockburn K, Gonzalez D, Boucher J, Xin T, Klein AM, Greco V: Homeostatic Epidermal Stem Cell Self-Renewal Is Driven by Local Differentiation. Cell Stem Cell. 2018 Nov 1; 2018 Sep 27. PMID: 30269903

Johnson DB, Bordeaux J, Kim JY, Vaupel C, Rimm DL, Ho TH, Joseph RW, Daud AI, Conry RM, Gaughan EM, Hernandez-Aya LF, Dimou A, Funchain P, Smithy J, Witte JS, McKee SB, Ko J, Wrangle JM, Dabbas B, Tangri S, Lameh J, Hall J, Markowitz J, Balko JM, Dakappagari N: Quantitative Spatial Profiling of PD-1/PD-L1 Interaction and HLA-DR/IDO-1 Predicts Improved Outcomes of Anti-PD-1 Therapies in Metastatic Melanoma. Clin Cancer Res. 2018 Nov 1; 2018 Jul 18. PMID: 30021908

Lu C, Romo-Bucheli D, Wang X, Janowczyk A, Ganesan S, Gilmore H, Rimm D, Madabhushi A: Nuclear shape and orientation features from H&E images predict survival in early-stage estrogen receptor-positive breast cancers. Lab Invest. 2018 Nov; 2018 Jun 29. PMID: 29959421

Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZS, Su X, Maganti A, Jiang C, Lu W, Zheng H, Bosenberg MW, Mehnert JM, Guo JY, Lattime E, Rabinowitz JD, White E: Autophagy maintains tumour growth through circulating arginine. Nature. 2018 Nov; 2018 Nov 14. PMID: 30429607

Acevedo-Alvarez M, Yeh J, Alvarez-Lugo L, Lu M, Sukumar N, Hill WG, Chai TC: Mouse urothelial genes associated with voiding behavior changes after ovariectomy and bladder lipopolysaccharide exposure. Neurourol Urodyn. 2018 Nov; 2018 Apr 23. PMID: 29682797

Hartman DJ, Ahmad F, Ferris RL, Rimm DL, Pantanowitz L: Utility of CD8 score by automated quantitative image analysis in head and neck squamous cell carcinoma. Oral Oncol. 2018 Nov; 2018 Oct 11. PMID: 30409313

Yang B, Wu H, Schnier PD, Liu Y, Liu J, Wang N, DeGrado WF, Wang L: Proximity-enhanced SuFEx chemical cross-linker for specific and multitargeting cross-linking mass spectrometry. Proc Natl Acad Sci U S A. 2018 Oct 30; 2018 Oct 15. PMID: 30322930

Kadry YA, Huet-Calderwood C, Simon B, Calderwood DA: Kindlin-2 interacts with a highly conserved surface of ILK to regulate focal adhesion localization and cell spreading. J Cell Sci. 2018 Oct 26; 2018 Oct 26. PMID: 30254023

Kanaujiya J, Bastow E, Luxmi R, Hao Z, Zattas D, Hochstrasser M, Reichenberger EJ, Chen IP: Rapid degradation of progressive ankylosis protein (ANKH) in craniometaphyseal dysplasia. Sci Rep. 2018 Oct 24; 2018 Oct 24. PMID: 30356088

Abelson B, Sun D, Que L, Nebel RA, Baker D, Popiel P, Amundsen CL, Chai T, Close C, DiSanto M, Fraser MO, Kielb SJ, Kuchel G, Mueller ER, Palmer MH, Parker-Autry C, Wolfe AJ, Damaser MS: Sex differences in lower urinary tract biology and physiology. Biol Sex Differ. 2018 Oct 22; 2018 Oct 22. PMID: 30343668

Sheetz JB, Lemmon MA: Flipping ATP to AMPlify Kinase Functions. Cell. 2018 Oct 18. PMID: 30340038

Chen Y, Zhou Z, Min W: Mitochondria, Oxidative Stress and Innate Immunity. Front Physiol. 2018; 2018 Oct 18. PMID: 30405440

Kumar A, Anderson KL, Swift MF, Hanein D, Volkmann N, Schwartz MA: Local Tension on Talin in Focal Adhesions Correlates with F-Actin Alignment at the Nanometer Scale. Biophys J. 2018 Oct 16; 2018 Sep 10. PMID: 30274833

Ong Q, Han W, Yang X: O-GlcNAc as an Integrator of Signaling Pathways. Front Endocrinol (Lausanne). 2018; 2018 Oct 16. PMID: 30464755

Hughes LD, Ghosh S, Rothlin CV: Cenabis Bene: Treg Cells Invite Macrophages to Dine. Immunity. 2018 Oct 16. PMID: 30332622

Miller MB, Wilson RS, Lam TT, Nairn AC, Picciotto MR: Evaluation of the Phosphoproteome of Mouse Alpha 4/Beta 2-Containing Nicotinic Acetylcholine Receptors In Vitro and In Vivo. Proteomes. 2018 Oct 15; 2018 Oct 15. PMID: 30326594

Bertholomey ML, Stone K, Lam TT, Bang S, Wu W, Nairn AC, Taylor JR, Torregrossa MM: Phosphoproteomic Analysis of the Amygdala Response to Adolescent Glucocorticoid Exposure Reveals G-Protein Coupled Receptor Kinase 2 as a Target for Reducing Motivation for Alcohol. Proteomes. 2018 Oct 12; 2018 Oct 12. PMID: 30322021

Mehrtash AB, Hochstrasser M: Ubiquitin-dependent protein degradation at the endoplasmic reticulum and nuclear envelope. Semin Cell Dev Biol. 2018 Oct 9; 2018 Oct 9. PMID: 30278225

Carlyle BC, Kitchen RR, Zhang J, Wilson RS, Lam TT, Rozowsky JS, Williams KR, Sestan N, Gerstein MB, Nairn AC: Isoform-Level Interpretation of High-Throughput Proteomics Data Enabled by Deep Integration with RNA-seq. J Proteome Res. 2018 Oct 5; 2018 Sep 6. PMID: 30125121

Chu EK, Kilic O, Cho H, Groisman A, Levchenko A: Self-induced mechanical stress can trigger biofilm formation in uropathogenic Escherichia coli. Nat Commun. 2018 Oct 5; 2018 Oct 5. PMID: 30291231

Sommer A, Lemmon MA: Smoothening out the patches. Science. 2018 Oct 5. PMID: 30287647

Vanaja KG, Timp W, Feinberg AP, Levchenko A: A Loss of Epigenetic Control Can Promote Cell Death through Reversing the Balance of Pathways in a Signaling Network. Mol Cell. 2018 Oct 4; 2018 Sep 20. PMID: 30244832

Axelrod D, Elson EL, Schlessinger J, Koppel DE: Reminiscences on the "Classic" 1976 FRAP Article in Biophysical Journal. Biophys J. 2018 Oct 2; 2018 Sep 4. PMID: 30224052

Xu Y, Wu D, Jiang Z, Zhang Y, Wang S, Ma Z, Hui B, Wang J, Qian W, Ge Z, Sun L: MiR-616-3p modulates cell proliferation and migration through targeting tissue factor pathway inhibitor 2 in preeclampsia. Cell Prolif. 2018 Oct; 2018 Jul 20. PMID: 30028057

Bonazzoli E, Predolini F, Cocco E, Bellone S, Altwerger G, Menderes G, Zammataro L, Bianchi A, Pettinella F, Riccio F, Han C, Yadav G, Lopez S, Manzano A, Manara P, Buza N, Hui P, Wong S, Litkouhi B, Ratner E, Silasi DA, Huang GS, Azodi M, Schwartz PE, Schlessinger J, Santin AD: Inhibition of BET Bromodomain Proteins with GS-5829 and GS-626510 in Uterine Serous Carcinoma, a Biologically Aggressive Variant of Endometrial Cancer. Clin Cancer Res. 2018 Oct 1; 2018 Jun 25. PMID: 29941483

Antonarakis ES, Small EJ, Petrylak DP, Quinn DI, Kibel AS, Chang NN, Dearstyne E, Harmon M, Campogan D, Haynes H, Vu T, Sheikh NA, Drake CG: Antigen-Specific CD8 Lytic Phenotype Induced by Sipuleucel-T in Hormone-Sensitive or Castration-Resistant Prostate Cancer and Association with Overall Survival. Clin Cancer Res. 2018 Oct 1; 2018 Jun 1. PMID: 29858218

Yamani A, Wu D, Waggoner L, Noah T, Koleske AJ, Finkelman F, Hogan SP: The vascular endothelial specific IL-4 receptor alpha-ABL1 kinase signaling axis regulates the severity of IgE-mediated anaphylactic reactions. J Allergy Clin Immunol. 2018 Oct; 2017 Nov 17. PMID: 29157947

Janjigian YY, Bendell J, Calvo E, Kim JW, Ascierto PA, Sharma P, Ott PA, Peltola K, Jaeger D, Evans J, de Braud F, Chau I, Harbison CT, Dorange C, Tschaika M, Le DT: CheckMate-032 Study: Efficacy and Safety of Nivolumab and Nivolumab Plus Ipilimumab in Patients With Metastatic Esophagogastric Cancer. J Clin Oncol. 2018 Oct 1; 2018 Aug 15. PMID: 30110194

Maisel A, Waldman A, Furlan K, Weil A, Sacotte K, Lazaroff JM, Lin K, Aranzazu D, Avram MM, Bell A, Cartee TV, Cazzaniga A, Chapas A, Crispin MK, Croix JA, DiGiorgio CM, Dover JS, Goldberg DJ, Goldman MP, Green JB, Griffin CL, Haimovic AD, Hausauer AK, Hernandez SL, Hsu S, Ibrahim O, Jones DH, Kaufman J, Kilmer SL, Lee NY, McDaniel DH, Schlessinger J, Tanzi E, Weiss ET, Weiss RA, Wu D, Poon E, Alam M: Self-reported Patient Motivations for Seeking Cosmetic Procedures. JAMA Dermatol. 2018 Oct 1. PMID: 30140900

Kilian N, Goryaynov A, Lessard MD, Hooker G, Toomre D, Rothman JE, Bewersdorf J: Assessing photodamage in live-cell STED microscopy. Nat Methods. 2018 Oct. PMID: 30275592

Iwamoto DV, Huehn A, Simon B, Huet-Calderwood C, Baldassarre M, Sindelar CV, Calderwood DA: Structural basis of the filamin A actin-binding domain interaction with F-actin. Nat Struct Mol Biol. 2018 Oct; 2018 Sep 17. PMID: 30224736

Di Modugno F, Spada S, Palermo B, Visca P, Iapicca P, Di Carlo A, Antoniani B, Sperduti I, Di Benedetto A, Terrenato I, Mottolese M, Gandolfi F, Facciolo F, Chen EI, Schwartz MA, Santoni A, Bissell MJ, Nisticò P: hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis. Oncogene. 2018 Oct; 2018 Jun 15. PMID: 29907768

Dieci MV, Radosevic-Robin N, Fineberg S, van den Eynden G, Ternes N, Penault-Llorca F, Pruneri G, D'Alfonso TM, Demaria S, Castaneda C, Sanchez J, Badve S, Michiels S, Bossuyt V, Rojo F, Singh B, Nielsen T, Viale G, Kim SR, Hewitt S, Wienert S, Loibl S, Rimm D, Symmans F, Denkert C, Adams S, Loi S, Salgado R, International Immuno-Oncology Biomarker Working Group on Breast Cancer.: Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer. Semin Cancer Biol. 2018 Oct; 2017 Oct 9. PMID: 29024776

Turk BE: Exceptionally Selective Substrate Targeting by the Metalloprotease Anthrax Lethal Factor. Adv Exp Med Biol. 2018 Sep 29; 2018 Sep 29. PMID: 30267305

Koduru SV, Sun BH, Walker JM, Zhu M, Simpson C, Dhodapkar M, Insogna KL: The contribution of cross-talk between the cell-surface proteins CD36 and CD47-TSP-1 in osteoclast formation and function. J Biol Chem. 2018 Sep 28; 2018 Aug 6. PMID: 30082316

Sweetnam C, Mocellin S, Krauthammer M, Knopf N, Baertsch R, Shrager J: Prototyping a precision oncology 3.0 rapid learning platform. BMC Bioinformatics. 2018 Sep 26; 2018 Sep 26. PMID: 30257653

Zhang X, Sessa WC, Fernández-Hernando C: Endothelial Transcytosis of Lipoproteins in Atherosclerosis. Front Cardiovasc Med. 2018; 2018 Sep 25. PMID: 30320124

Mervosh NL, Wilson R, Rauniyar N, Hofford RS, Kutlu MG, Calipari ES, Lam TT, Kiraly DD: Granulocyte-Colony-Stimulating Factor Alters the Proteomic Landscape of the Ventral Tegmental Area. Proteomes. 2018 Sep 23; 2018 Sep 23. PMID: 30249060

Kim DH, Ewald AJ, Park J, Kshitiz, Kwak M, Gray RS, Su CY, Seo J, An SS, Levchenko A: Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread. Sci Rep. 2018 Sep 21; 2018 Sep 21. PMID: 30242256

Ang K, Sanchez Rangel E, Yuan Q, Wu D, Carpenter TO, Insogna K: Skeletal disease in a father and daughter with a novel monoallelic WNT1 mutation. Bone Rep. 2018 Dec; 2018 Sep 19. PMID: 30364642

Insogna KL: Primary Hyperparathyroidism. N Engl J Med. 2018 Sep 13. PMID: 30207907

Breslow DK: Pericentrin Knocks Down Cilia in Trisomy 21. Dev Cell. 2018 Sep 10. PMID: 30205034

Qian K, Wang S, Fu M, Zhou J, Singh JP, Li MD, Yang Y, Zhang K, Wu J, Nie Y, Ruan HB, Yang X: Transcriptional regulation of O-GlcNAc homeostasis is disrupted in pancreatic cancer. J Biol Chem. 2018 Sep 7; 2018 Jul 23. PMID: 30037904

Xu Y, Wu D, Liu J, Huang S, Zuo Q, Xia X, Jiang Y, Wang S, Chen Y, Wang T, Sun L: Downregulated lncRNA HOXA11-AS Affects Trophoblast Cell Proliferation and Migration by Regulating RND3 and HOXA7 Expression in PE. Mol Ther Nucleic Acids. 2018 Sep 7; 2018 May 29. PMID: 30195759

Zwick RK, Rudolph MC, Shook BA, Holtrup B, Roth E, Lei V, Van Keymeulen A, Seewaldt V, Kwei S, Wysolmerski J, Rodeheffer MS, Horsley V: Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation. Nat Commun. 2018 Sep 4; 2018 Sep 4. PMID: 30181538

Rawat RR, Ruderman D, Macklin P, Rimm DL, Agus DB: Correlating nuclear morphometric patterns with estrogen receptor status in breast cancer pathologic specimens. NPJ Breast Cancer. 2018; 2018 Sep 4. PMID: 30211313

Flaig TW, Spiess PE, Agarwal N, Bangs R, Boorjian SA, Buyyounouski MK, Downs TM, Efstathiou JA, Friedlander T, Greenberg RE, Guru KA, Hahn N, Herr HW, Hoimes C, Inman BA, Jimbo M, Kader AK, Lele SM, Meeks JJ, Michalski J, Montgomery JS, Pagliaro LC, Pal SK, Patterson A, Petrylak DP, Plimack ER, Pohar KS, Porter MP, Preston MA, Sexton WJ, Siefker-Radtke AO, Tward J, Wile G, Johnson-Chilla A, Dwyer MA, Gurski LA: NCCN Guidelines Insights: Bladder Cancer, Version 5.2018. J Natl Compr Canc Netw. 2018 Sep. PMID: 30181416

Madiraju AK, Qiu Y, Perry RJ, Rahimi Y, Zhang XM, Zhang D, Camporez JG, Cline GW, Butrico GM, Kemp BE, Casals G, Steinberg GR, Vatner DF, Petersen KF, Shulman GI: Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo. Nat Med. 2018 Sep; 2018 Jul 23. PMID: 30038219

Rauniyar N, Yu X, Cantley J, Voss EZ, Belcher J, Colangelo CM, Stone KL, Dahl N, Parikh C, Lam TT, Cantley LG: Quantification of Urinary Protein Biomarkers of Autosomal Dominant Polycystic Kidney Disease by Parallel Reaction Monitoring. Proteomics Clin Appl. 2018 Sep; 2018 May 2. PMID: 29573172

Singh AK, Aryal B, Zhang X, Fan Y, Price NL, Suárez Y, Fernández-Hernando C: Posttranscriptional regulation of lipid metabolism by non-coding RNAs and RNA binding proteins. Semin Cell Dev Biol. 2018 Sep; 2017 Dec 6. PMID: 29183708

Yang Y, Culpitt T, Tao Z, Hammes-Schiffer S: Stability conditions and local minima in multicomponent Hartree-Fock and density functional theory. J Chem Phys. 2018 Aug 28. PMID: 30193501

Nagarajan A, Malvi P, Wajapeyee N: Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression. Front Endocrinol (Lausanne). 2018; 2018 Aug 24. PMID: 30197623

Scherer AN, Anand NS, Koleske AJ: Cortactin stabilization of actin requires actin-binding repeats and linker, is disrupted by specific substitutions, and is independent of nucleotide state. J Biol Chem. 2018 Aug 24; 2018 Jun 21. PMID: 29929984

Rossi J, Paczkowski P, Shen YW, Morse K, Flynn B, Kaiser A, Ng C, Gallatin K, Cain T, Fan R, Mackay S, Heath JR, Rosenberg SA, Kochenderfer JN, Zhou J, Bot A: Preinfusion polyfunctional anti-CD19 chimeric antigen receptor T cells are associated with clinical outcomes in NHL. Blood. 2018 Aug 23; 2018 Jun 12. PMID: 29895668

Rodriguez-Bravo V, Pippa R, Song WM, Carceles-Cordon M, Dominguez-Andres A, Fujiwara N, Woo J, Koh AP, Ertel A, Lokareddy RK, Cuesta-Dominguez A, Kim RS, Rodriguez-Fernandez I, Li P, Gordon R, Hirschfield H, Prats JM, Reddy EP, Fatatis A, Petrylak DP, Gomella L, Kelly WK, Lowe SW, Knudsen KE, Galsky MD, Cingolani G, Lujambio A, Hoshida Y, Domingo-Domenech J: Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import. Cell. 2018 Aug 23; 2018 Aug 9. PMID: 30100187

Goel RK, Meyer M, Paczkowska M, Reimand J, Vizeacoumar F, Vizeacoumar F, Lam TT, Lukong KE: Global phosphoproteomic analysis identifies SRMS-regulated secondary signaling intermediates. Proteome Sci. 2018; 2018 Aug 18. PMID: 30140170

Zhou HJ, Xu Z, Wang Z, Zhang H, Simons M, Min W: SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis. Nat Commun. 2018 Aug 17; 2018 Aug 17. PMID: 30120232

Reshetnyak AV, Mohanty J, Tomé F, Puleo DE, Plotnikov AN, Ahmed M, Kaur N, Poliakov A, Cinnaiyan AM, Lax I, Schlessinger J: Identification of a biologically active fragment of ALK and LTK-Ligand 2 (augmentor-α). Proc Natl Acad Sci U S A. 2018 Aug 14; 2018 Jul 30. PMID: 30061385

Jin L, Chun J, Pan C, Li D, Lin R, Alesi GN, Wang X, Kang HB, Song L, Wang D, Zhang G, Fan J, Boggon TJ, Zhou L, Kowalski J, Qu CK, Steuer CE, Chen GZ, Saba NF, Boise LH, Owonikoko TK, Khuri FR, Magliocca KR, Shin DM, Lonial S, Kang S: MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation. Cancer Cell. 2018 Aug 13; 2018 Jul 19. PMID: 30033091

Zhang F, Zarkada G, Han J, Li J, Dubrac A, Ola R, Genet G, Boyé K, Michon P, Künzel SE, Camporez JP, Singh AK, Fong GH, Simons M, Tso P, Fernández-Hernando C, Shulman GI, Sessa WC, Eichmann A: Lacteal junction zippering protects against diet-induced obesity. Science. 2018 Aug 10. PMID: 30093598

Barber KW, Miller CJ, Jun JW, Lou HJ, Turk BE, Rinehart J: Kinase Substrate Profiling Using a Proteome-wide Serine-Oriented Human Peptide Library. Biochemistry. 2018 Aug 7; 2018 Jun 19. PMID: 29920078

Levy AD, Xiao X, Shaw JE, Sudarsana Devi SP, Katrancha SM, Bennett AM, Greer CA, Howe JR, Machida K, Koleske AJ: Noonan Syndrome-Associated SHP2 Dephosphorylates GluN2B to Regulate NMDA Receptor Function. Cell Rep. 2018 Aug 7. PMID: 30089263

Emptage RP, Lemmon MA, Ferguson KM, Marmorstein R: Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain. Structure. 2018 Aug 7; 2018 Jun 28. PMID: 30099988

Hapak SM, Rothlin CV, Ghosh S: PAR3-PAR6-atypical PKC polarity complex proteins in neuronal polarization. Cell Mol Life Sci. 2018 Aug; 2018 Apr 25. PMID: 29696344

Janostiak R, Vyas M, Cicek AF, Wajapeyee N, Harigopal M: Loss of c-KIT expression in breast cancer correlates with malignant transformation of breast epithelium and is mediated by KIT gene promoter DNA hypermethylation. Exp Mol Pathol. 2018 Aug; 2018 May 28. PMID: 29852185

Insogna KL, Briot K, Imel EA, Kamenický P, Ruppe MD, Portale AA, Weber T, Pitukcheewanont P, Cheong HI, Jan de Beur S, Imanishi Y, Ito N, Lachmann RH, Tanaka H, Perwad F, Zhang L, Chen CY, Theodore-Oklota C, Mealiffe M, San Martin J, Carpenter TO, AXLES 1 Investigators.: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial Evaluating the Efficacy of Burosumab, an Anti-FGF23 Antibody, in Adults With X-Linked Hypophosphatemia: Week 24 Primary Analysis. J Bone Miner Res. 2018 Aug; 2018 Jun 26. PMID: 29947083

Flannery CA, Choe GH, Cooke KM, Fleming AG, Radford CC, Kodaman PH, Jurczak MJ, Kibbey RG, Taylor HS: Insulin Regulates Glycogen Synthesis in Human Endometrial Glands Through Increased GYS2. J Clin Endocrinol Metab. 2018 Aug 1. PMID: 29726999

Gupta S, Mani NR, Carvajal-Hausdorf DE, Bossuyt V, Ho K, Weidler J, Wong W, Rhees B, Bates M, Rimm DL: Macrodissection prior to closed system RT-qPCR is not necessary for estrogen receptor and HER2 concordance with IHC/FISH in breast cancer. Lab Invest. 2018 Aug; 2018 Jun 1. PMID: 29858579

Bugide S, Janostiak R, Wajapeyee N: Epigenetic Mechanisms Dictating Eradication of Cancer by Natural Killer Cells. Trends Cancer. 2018 Aug; 2018 Jul 3. PMID: 30064663

Yang Y, Kang D, Nguyen LA, Smithline ZB, Pannecouque C, Zhan P, Liu X, Steitz TA: Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d]pyrimidine non-nucleoside inhibitors. Elife. 2018 Jul 25; 2018 Jul 25. PMID: 30044217

Brahmer JR, Govindan R, Anders RA, Antonia SJ, Sagorsky S, Davies MJ, Dubinett SM, Ferris A, Gandhi L, Garon EB, Hellmann MD, Hirsch FR, Malik S, Neal JW, Papadimitrakopoulou VA, Rimm DL, Schwartz LH, Sepesi B, Yeap BY, Rizvi NA, Herbst RS: The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of non-small cell lung cancer (NSCLC). J Immunother Cancer. 2018 Jul 17; 2018 Jul 17. PMID: 30012210

Bellone S, Buza N, Choi J, Zammataro L, Gay L, Elvin J, Rimm DL, Liu Y, Ratner ES, Schwartz PE, Santin AD: Exceptional Response to Pembrolizumab in a Metastatic, Chemotherapy/Radiation-Resistant Ovarian Cancer Patient Harboring a PD-L1-Genetic Rearrangement. Clin Cancer Res. 2018 Jul 15; 2018 Jan 19. PMID: 29351920

Wang Y, Nasiri AR, Damsky WE, Perry CJ, Zhang XM, Rabin-Court A, Pollak MN, Shulman GI, Perry RJ: Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon Cancer. Cell Rep. 2018 Jul 3. PMID: 29972790

Ebhardt HA, Root A, Liu Y, Gauthier NP, Sander C, Aebersold R: Systems pharmacology using mass spectrometry identifies critical response nodes in prostate cancer. NPJ Syst Biol Appl. 2018; 2018 Jul 2. PMID: 29977602

Kitay AM, Schneebacher MT, Schmitt A, Heschl K, Kopic S, Alfadda T, Alsaihati A, Link A, Geibel JP: Modulations in extracellular calcium lead to H+-ATPase-dependent acid secretion: a clarification of PPI failure. Am J Physiol Gastrointest Liver Physiol. 2018 Jul 1; 2018 Mar 8. PMID: 29517927

Fonseca MC, França A, Florentino RM, Fonseca RC, Lima Filho ACM, Vidigal PTV, Oliveira AG, Dubuquoy L, Nathanson MH, Leite MF: Cholesterol-enriched membrane microdomains are needed for insulin signaling and proliferation in hepatic cells. Am J Physiol Gastrointest Liver Physiol. 2018 Jul 1; 2018 Feb 22. PMID: 29471671

Pal SK, Rosenberg JE, Hoffman-Censits JH, Berger R, Quinn DI, Galsky MD, Wolf J, Dittrich C, Keam B, Delord JP, Schellens JHM, Gravis G, Medioni J, Maroto P, Sriuranpong V, Charoentum C, Burris HA, Grünwald V, Petrylak D, Vaishampayan U, Gez E, De Giorgi U, Lee JL, Voortman J, Gupta S, Sharma S, Mortazavi A, Vaughn DJ, Isaacs R, Parker K, Chen X, Yu K, Porter D, Graus Porta D, Bajorin DF: Efficacy of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Inhibitor, in Patients with Previously Treated Advanced Urothelial Carcinoma with FGFR3 Alterations. Cancer Discov. 2018 Jul; 2018 May 30. PMID: 29848605

He L, Pierce RW, Min W: Rare and Low-Frequency Variant of ARHGEF17 Is Associated With Intracranial Aneurysms. Circ Genom Precis Med. 2018 Jul. PMID: 29997229

Sun Q, Rabbani P, Takeo M, Lee SH, Lim CH, Noel ES, Taketo MM, Myung P, Millar S, Ito M: Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing. J Invest Dermatol. 2018 Jul; 2018 Feb 8. PMID: 29428355

Hapak SM, Ghosh S, Rothlin CV: Axon Regeneration: Antagonistic Signaling Pairs in Neuronal Polarization. Trends Mol Med. 2018 Jul; 2018 Jun 19. PMID: 29934283

Stevens LE, Arnal-Estapé A, Nguyen DX: Pre-Conditioning the Airways of Mice with Bleomycin Increases the Efficiency of Orthotopic Lung Cancer Cell Engraftment. J Vis Exp. 2018 Jun 28; 2018 Jun 28. PMID: 30010648

Fan PD, Narzisi G, Jayaprakash AD, Venturini E, Robine N, Smibert P, Germer S, Yu HA, Jordan EJ, Paik PK, Janjigian YY, Chaft JE, Wang L, Jungbluth AA, Middha S, Spraggon L, Qiao H, Lovly CM, Kris MG, Riely GJ, Politi K, Varmus H, Ladanyi M: YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics. Proc Natl Acad Sci U S A. 2018 Jun 26; 2018 Jun 6. PMID: 29875142

Mis MA, Rogers MF, Jeffries AR, Wilbrey AL, Chen L, Yang Y, Dib-Hajj S, Waxman SG, Stevens EB, Randall AD: Differential aging-related changes in neurophysiology and gene expression in IB4-positive and IB4-negative nociceptive neurons. Aging Cell. 2018 Jun 25; 2018 Jun 25. PMID: 29943484

Lu M, Li JR, Alvarez-Lugo L, Li Y, Yu S, Li X, Shi B, Chai TC: Lipopolysaccharide stimulates BK channel activity in bladder umbrella cells. Am J Physiol Cell Physiol. 2018 Jun 1; 2018 Feb 21. PMID: 29466671

Yang Y, Adi T, Effraim PR, Chen L, Dib-Hajj SD, Waxman SG: Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Nav 1.7 mutation I234T. Br J Pharmacol. 2018 Jun; 2017 Jul 30. PMID: 28658526

Foldi J, Mougalian S, Silber A, Lannin D, Killelea B, Chagpar A, Horowitz N, Frederick C, Rispoli L, Burrello T, Abu-Khalaf M, Sabbath K, Sanft T, Brandt DS, Hofstatter EW, Hatzis C, DiGiovanna MP, Pusztai L: Single-arm, neoadjuvant, phase II trial of pertuzumab and trastuzumab administered concomitantly with weekly paclitaxel followed by 5-fluoruracil, epirubicin, and cyclophosphamide (FEC) for stage I-III HER2-positive breast cancer. Breast Cancer Res Treat. 2018 Jun; 2018 Feb 2. PMID: 29396664

Sullivan R, Abraham A, Simpson C, Olear E, Carpenter T, Deng Y, Chen C, Insogna KL: Three-Month Randomized Clinical Trial of Nasal Calcitonin in Adults with X-linked Hypophosphatemia. Calcif Tissue Int. 2018 Jun; 2018 Jan 30. PMID: 29383408

Weiss RM: Legends in Urology. Can J Urol. 2018 Jun. PMID: 29900814

Wilson FH, Politi K: ERBB Signaling Interrupted: Targeting Ligand-Induced Pathway Activation. Cancer Discov. 2018 Jun. PMID: 29858224

Vaughn DJ, Bellmunt J, Fradet Y, Lee JL, Fong L, Vogelzang NJ, Climent MA, Petrylak DP, Choueiri TK, Necchi A, Gerritsen W, Gurney H, Quinn DI, Culine S, Sternberg CN, Mai Y, Li H, Perini RF, Bajorin DF, de Wit R: Health-Related Quality-of-Life Analysis From KEYNOTE-045: A Phase III Study of Pembrolizumab Versus Chemotherapy for Previously Treated Advanced Urothelial Cancer. J Clin Oncol. 2018 Jun 1; 2018 Mar 28. PMID: 29590008

Jacobsen FA, Scherer AN, Mouritsen J, Bragadóttir H, Thomas Bäckström B, Sardar S, Holmberg D, Koleske AJ, Andersson Å: A Role for the Non-Receptor Tyrosine Kinase Abl2/Arg in Experimental Neuroinflammation. J Neuroimmune Pharmacol. 2018 Jun; 2018 Mar 17. PMID: 29550892

Gettinger SN, Wurtz A, Goldberg SB, Rimm D, Schalper K, Kaech S, Kavathas P, Chiang A, Lilenbaum R, Zelterman D, Politi K, Herbst RS: Clinical Features and Management of Acquired Resistance to PD-1 Axis Inhibitors in 26 Patients With Advanced Non-Small Cell Lung Cancer. J Thorac Oncol. 2018 Jun; 2018 Mar 22. PMID: 29578107

Kim AS, Bartley AN, Bridge JA, Kamel-Reid S, Lazar AJ, Lindeman NI, Long TA, Merker JD, Rai AJ, Rimm DL, Rothberg PG, Vasalos P, Moncur JT: Comparison of Laboratory-Developed Tests and FDA-Approved Assays for BRAF, EGFR, and KRAS Testing. JAMA Oncol. 2018 Jun 1. PMID: 29242895

Pelekanou V, Barlow WE, Nahleh ZA, Wasserman B, Lo YC, von Wahlde MK, Hayes D, Hortobagyi GN, Gralow J, Tripathy D, Porter P, Szekely B, Hatzis C, Rimm DL, Pusztai L: Tumor-Infiltrating Lymphocytes and PD-L1 Expression in Pre- and Posttreatment Breast Cancers in the SWOG S0800 Phase II Neoadjuvant Chemotherapy Trial. Mol Cancer Ther. 2018 Jun; 2018 Mar 27. PMID: 29588392

Sajic T, Liu Y, Arvaniti E, Surinova S, Williams EG, Schiess R, Hüttenhain R, Sethi A, Pan S, Brentnall TA, Chen R, Blattmann P, Friedrich B, Niméus E, Malander S, Omlin A, Gillessen S, Claassen M, Aebersold R: Similarities and Differences of Blood N-Glycoproteins in Five Solid Carcinomas at Localized Clinical Stage Analyzed by SWATH-MS. Cell Rep. 2018 May 29. PMID: 29847809

Perry RJ: Leptin revisited: The role of leptin in starvation. Mol Cell Oncol. 2018; 2018 May 29. PMID: 30263938

Misra A, Feng Z, Chandran RR, Kabir I, Rotllan N, Aryal B, Sheikh AQ, Ding L, Qin L, Fernández-Hernando C, Tellides G, Greif DM: Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells. Nat Commun. 2018 May 25; 2018 May 25. PMID: 29802249

Aranda JF, Rathjen S, Johannes L, Fernández-Hernando C: MicroRNA 199a-5p Attenuates Retrograde Transport and Protects against Toxin-Induced Inhibition of Protein Biosynthesis. Mol Cell Biol. 2018 Jun 1; 2018 May 15. PMID: 29555727

Liao X, Shen Y, Zhang R, Sugi K, Vasudevan NT, Alaiti MA, Sweet DR, Zhou L, Qing Y, Gerson SL, Fu C, Wynshaw-Boris A, Hu R, Schwartz MA, Fujioka H, Richardson B, Cameron MJ, Hayashi H, Stamler JS, Jain MK: Distinct roles of resident and nonresident macrophages in nonischemic cardiomyopathy. Proc Natl Acad Sci U S A. 2018 May 15; 2018 Apr 30. PMID: 29712858

Desir GV, Churchwell KB: New chief of cardiovascular medicine at Yale School of Medicine. Eur Heart J. 2018 May 14. PMID: 29762704

Bisserier M, Wajapeyee N: Mechanisms of resistance to EZH2 inhibitors in diffuse large B-cell lymphomas. Blood. 2018 May 10; 2018 Mar 23. PMID: 29572378

Araque KA, Kadayakkara DK, Gigauri N, Sheehan D, Majumdar S, Buller G, Flannery CA: Reducing severe hypoglycaemia in hospitalised patients with diabetes: Early outcomes of standardised reporting and management. BMJ Open Qual. 2018; 2018 May 5. PMID: 29756070

Fernández-Hernando C, Suárez Y: MicroRNAs in endothelial cell homeostasis and vascular disease. Curr Opin Hematol. 2018 May. PMID: 29547400

Bennett AM: DUSPs, twists and turns in the Journey to Vascular Inflammation. FEBS J. 2018 May; 2018 Apr 22. PMID: 29682902

Singh AK, Aryal B, Chaube B, Rotllan N, Varela L, Horvath TL, Suárez Y, Fernández-Hernando C: Brown adipose tissue derived ANGPTL4 controls glucose and lipid metabolism and regulates thermogenesis. Mol Metab. 2018 May; 2018 Mar 29. PMID: 29627378

Shi H, Munk A, Nielsen TS, Daughtry MR, Larsson L, Li S, Høyer KF, Geisler HW, Sulek K, Kjøbsted R, Fisher T, Andersen MM, Shen Z, Hansen UK, England EM, Cheng Z, Højlund K, Wojtaszewski JFP, Yang X, Hulver MW, Helm RF, Treebak JT, Gerrard DE: Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity. Mol Metab. 2018 May; 2018 Feb 24. PMID: 29525407

Robichaux JP, Elamin YY, Tan Z, Carter BW, Zhang S, Liu S, Li S, Chen T, Poteete A, Estrada-Bernal A, Le AT, Truini A, Nilsson MB, Sun H, Roarty E, Goldberg SB, Brahmer JR, Altan M, Lu C, Papadimitrakopoulou V, Politi K, Doebele RC, Wong KK, Heymach JV: Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in non-small cell lung cancer. Nat Med. 2018 May; 2018 Apr 23. PMID: 29686424

Miller CJ, Turk BE: Homing in: Mechanisms of Substrate Targeting by Protein Kinases. Trends Biochem Sci. 2018 May; 2018 Mar 12. PMID: 29544874

Long L, Yin M, Min W: 3D Co-culture System of Tumor-associated Macrophages and Ovarian Cancer Cells. Bio Protoc. 2018 Apr 20. PMID: 29770354

Zhang J, Chen C, Li L, Zhou HJ, Li F, Zhang H, Yu L, Chen Y, Min W: Endothelial AIP1 Regulates Vascular Remodeling by Suppressing NADPH Oxidase-2. Front Physiol. 2018; 2018 Apr 20. PMID: 29731721

Chibly AM, Wong WY, Pier M, Cheng H, Mu Y, Chen J, Ghosh S, Limesand KH: aPKCζ-dependent Repression of Yap is Necessary for Functional Restoration of Irradiated Salivary Glands with IGF-1. Sci Rep. 2018 Apr 20; 2018 Apr 20. PMID: 29679075

Schwartz MA, Vestweber D, Simons M: A unifying concept in vascular health and disease. Science. 2018 Apr 20. PMID: 29674582

Goldberg SB, Narayan A, Kole AJ, Decker RH, Teysir J, Carriero NJ, Lee A, Nemati R, Nath SK, Mane SM, Deng Y, Sukumar N, Zelterman D, Boffa DJ, Politi K, Gettinger SN, Wilson LD, Herbst RS, Patel AA: Early Assessment of Lung Cancer Immunotherapy Response via Circulating Tumor DNA. Clin Cancer Res. 2018 Apr 15; 2018 Jan 12. PMID: 29330207

Bugide S, Green MR, Wajapeyee N: Inhibition of Enhancer of zeste homolog 2 (EZH2) induces natural killer cell-mediated eradication of hepatocellular carcinoma cells. Proc Natl Acad Sci U S A. 2018 Apr 10; 2018 Mar 26. PMID: 29581297

Yang Y, Culpitt T, Hammes-Schiffer S: Multicomponent Time-Dependent Density Functional Theory: Proton and Electron Excitation Energies. J Phys Chem Lett. 2018 Apr 5; 2018 Mar 26. PMID: 29553738

Kim JW, Shin MS, Kang Y, Kang I, Petrylak DP: Immune Analysis of Radium-223 in Patients With Metastatic Prostate Cancer. Clin Genitourin Cancer. 2018 Apr; 2017 Oct 24. PMID: 29137877

Lawan A, Min K, Zhang L, Canfran-Duque A, Jurczak MJ, Camporez JPG, Nie Y, Gavin TP, Shulman GI, Fernandez-Hernando C, Bennett AM: Skeletal Muscle-Specific Deletion of MKP-1 Reveals a p38 MAPK/JNK/Akt Signaling Node That Regulates Obesity-Induced Insulin Resistance. Diabetes. 2018 Apr; 2018 Jan 9. PMID: 29317435

Krauthammer M: Unraveling the etiology of primary malignant melanoma of the esophagus. J Thorac Dis. 2018 Apr. PMID: 29850187

Petrylak DP, Powles T, Bellmunt J, Braiteh F, Loriot Y, Morales-Barrera R, Burris HA, Kim JW, Ding B, Kaiser C, Fassò M, O'Hear C, Vogelzang NJ: Atezolizumab (MPDL3280A) Monotherapy for Patients With Metastatic Urothelial Cancer: Long-term Outcomes From a Phase 1 Study. JAMA Oncol. 2018 Apr 1. PMID: 29423515

Kofler N, Corti F, Rivera-Molina F, Deng Y, Toomre D, Simons M: The Rab-effector protein RABEP2 regulates endosomal trafficking to mediate vascular endothelial growth factor receptor-2 (VEGFR2)-dependent signaling. J Biol Chem. 2018 Mar 30; 2018 Feb 7. PMID: 29425100

Marholz LJ, Zeringo NA, Lou HJ, Turk BE, Parker LL: In Silico Design and in Vitro Characterization of Universal Tyrosine Kinase Peptide Substrates. Biochemistry. 2018 Mar 27; 2018 Mar 12. PMID: 29528224

Park J, Kim DH, Levchenko A: Topotaxis: A New Mechanism of Directed Cell Migration in Topographic ECM Gradients. Biophys J. 2018 Mar 27. PMID: 29590582

Aryal B, Singh AK, Zhang X, Varela L, Rotllan N, Goedeke L, Chaube B, Camporez JP, Vatner DF, Horvath TL, Shulman GI, Suárez Y, Fernández-Hernando C: Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis. JCI Insight. 2018 Mar 22; 2018 Mar 22. PMID: 29563332

Miguel V, Cui JY, Daimiel L, Espinosa-Díez C, Fernández-Hernando C, Kavanagh TJ, Lamas S: The Role of MicroRNAs in Environmental Risk Factors, Noise-Induced Hearing Loss, and Mental Stress. Antioxid Redox Signal. 2018 Mar 20; 2017 Jun 30. PMID: 28562070

Qiu Y, Perry RJ, Camporez JG, Zhang XM, Kahn M, Cline GW, Shulman GI, Vatner DF: In vivo studies on the mechanism of methylene cyclopropyl acetic acid and methylene cyclopropyl glycine-induced hypoglycemia. Biochem J. 2018 Mar 20; 2018 Mar 20. PMID: 29483297

Moore LM, Wilkinson R, Altan M, Toki M, Carvajal-Hausdorf DE, McGuire J, Ehrlich BE, Rimm DL: An assessment of neuronal calcium sensor-1 and response to neoadjuvant chemotherapy in breast cancer patients. NPJ Breast Cancer. 2018; 2018 Mar 12. PMID: 29560416

Correa BRS, Hu J, Penalva LOF, Schlegel R, Rimm DL, Galante PAF, Agarwal S: Patient-derived conditionally reprogrammed cells maintain intra-tumor genetic heterogeneity. Sci Rep. 2018 Mar 6; 2018 Mar 6. PMID: 29511269

Aisner DL, Sholl LM, Berry LD, Rossi MR, Chen H, Fujimoto J, Moreira AL, Ramalingam SS, Villaruz LC, Otterson GA, Haura E, Politi K, Glisson B, Cetnar J, Garon EB, Schiller J, Waqar SN, Sequist LV, Brahmer J, Shyr Y, Kugler K, Wistuba II, Johnson BE, Minna JD, Kris MG, Bunn PA, Kwiatkowski DJ, LCMC2 investigators.: The Impact of Smoking and TP53 Mutations in Lung Adenocarcinoma Patients with Targetable Mutations-The Lung Cancer Mutation Consortium (LCMC2). Clin Cancer Res. 2018 Mar 1; 2017 Dec 7. PMID: 29217530

Rackow BW, Vanden Brink H, Hammers L, Flannery CA, Lujan ME, Burgert TS: Ovarian Morphology by Transabdominal Ultrasound Correlates With Reproductive and Metabolic Disturbance in Adolescents With PCOS. J Adolesc Health. 2018 Mar; 2017 Dec 6. PMID: 29217212

Acs B, Rimm DL: Not Just Digital Pathology, Intelligent Digital Pathology. JAMA Oncol. 2018 Mar 1. PMID: 29392271

Hickey CM, Xie Y, Hochstrasser M: DNA binding by the MATα2 transcription factor controls its access to alternative ubiquitin-modification pathways. Mol Biol Cell. 2018 Mar 1; 2018 Jan 3. PMID: 29298839

Breslow DK, Hoogendoorn S, Kopp AR, Morgens DW, Vu BK, Kennedy MC, Han K, Li A, Hess GT, Bassik MC, Chen JK, Nachury MV: A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Nat Genet. 2018 Mar; 2018 Feb 19. PMID: 29459677

Perry RJ, Shulman GI: The Role of Leptin in Maintaining Plasma Glucose During Starvation. Postdoc J. 2018 Mar. PMID: 29682594

Yang Y, Mis MA, Estacion M, Dib-Hajj SD, Waxman SG: NaV1.7 as a Pharmacogenomic Target for Pain: Moving Toward Precision Medicine. Trends Pharmacol Sci. 2018 Mar; 2018 Jan 20. PMID: 29370938

Wang Z, Kim MS, Martinez-Ferrando I, Koleske AJ, Pandey A, Cole PA: Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase. Biochemistry. 2018 Feb 27; 2018 Feb 6. PMID: 29341593

Hara M, Lourido S, Petrova B, Lou HJ, Von Stetina JR, Kashevsky H, Turk BE, Orr-Weaver TL: Identification of PNG kinase substrates uncovers interactions with the translational repressor TRAL in the oocyte-to-embryo transition. Elife. 2018 Feb 26; 2018 Feb 26. PMID: 29480805

Shams-White MM, Chung M, Fu Z, Insogna KL, Karlsen MC, LeBoff MS, Shapses SA, Sackey J, Shi J, Wallace TC, Weaver CM: Animal versus plant protein and adult bone health: A systematic review and meta-analysis from the National Osteoporosis Foundation. PLoS One. 2018; 2018 Feb 23. PMID: 29474360

Price NL, Singh AK, Rotllan N, Goedeke L, Wing A, Canfrán-Duque A, Diaz-Ruiz A, Araldi E, Baldán Á, Camporez JP, Suárez Y, Rodeheffer MS, Shulman GI, de Cabo R, Fernández-Hernando C: Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance. Cell Rep. 2018 Feb 20. PMID: 29466739

Fang JS, Coon BG, Gillis N, Chen Z, Qiu J, Chittenden TW, Burt JM, Schwartz MA, Hirschi KK: Addendum: Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Nat Commun. 2018 Feb 14; 2018 Feb 14. PMID: 29445140

Ouyang X, Han SN, Zhang JY, Dioletis E, Nemeth BT, Pacher P, Feng D, Bataller R, Cabezas J, Stärkel P, Caballeria J, Pongratz RL, Cai SY, Schnabl B, Hoque R, Chen Y, Yang WH, Garcia-Martinez I, Wang FS, Gao B, Torok NJ, Kibbey RG, Mehal WZ: Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1α Transactivation in Steatohepatitis. Cell Metab. 2018 Feb 6. PMID: 29414684

Liu L, Thaker TM, Freed DM, Frazier N, Malhotra K, Lemmon MA, Jura N: Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23. Structure. 2018 Feb 6; 2018 Jan 18. PMID: 29358026

Ha BH, Boggon TJ: The crystal structure of pseudokinase PEAK1 (Sugen kinase 269) reveals an unusual catalytic cleft and a novel mode of kinase fold dimerization. J Biol Chem. 2018 Feb 2; 2017 Dec 6. PMID: 29212708

Zhang EY, Ha BH, Boggon TJ: PAK4 crystal structures suggest unusual kinase conformational movements. Biochim Biophys Acta Proteins Proteom. 2018 Feb; 2017 Oct 7. PMID: 28993291

Corbit KC, Camporez JPG, Edmunds LR, Tran JL, Vera NB, Erion DM, Deo RC, Perry RJ, Shulman GI, Jurczak MJ, Weiss EJ: Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. Diabetes. 2018 Feb; 2017 Dec 4. PMID: 29203511

Turk BE: Glycogen synthase kinase-3β regulation: another kinase gets in on the AKT. FEBS Lett. 2018 Feb; 2018 Feb 8. PMID: 29417553

Chang CF, Goods BA, Askenase MH, Hammond MD, Renfroe SC, Steinschneider AF, Landreneau MJ, Ai Y, Beatty HE, da Costa LHA, Mack M, Sheth KN, Greer DM, Huttner A, Coman D, Hyder F, Ghosh S, Rothlin CV, Love JC, Sansing LH: Erythrocyte efferocytosis modulates macrophages towards recovery after intracerebral hemorrhage. J Clin Invest. 2018 Feb 1; 2017 Dec 18. PMID: 29251628

Giri VN, Knudsen KE, Kelly WK, Abida W, Andriole GL, Bangma CH, Bekelman JE, Benson MC, Blanco A, Burnett A, Catalona WJ, Cooney KA, Cooperberg M, Crawford DE, Den RB, Dicker AP, Eggener S, Fleshner N, Freedman ML, Hamdy FC, Hoffman-Censits J, Hurwitz MD, Hyatt C, Isaacs WB, Kane CJ, Kantoff P, Karnes RJ, Karsh LI, Klein EA, Lin DW, Loughlin KR, Lu-Yao G, Malkowicz SB, Mann MJ, Mark JR, McCue PA, Miner MM, Morgan T, Moul JW, Myers RE, Nielsen SM, Obeid E, Pavlovich CP, Peiper SC, Penson DF, Petrylak D, Pettaway CA, Pilarski R, Pinto PA, Poage W, Raj GV, Rebbeck TR, Robson ME, Rosenberg MT, Sandler H, Sartor O, Schaeffer E, Schwartz GF, Shahin MS, Shore ND, Shuch B, Soule HR, Tomlins SA, Trabulsi EJ, Uzzo R, Vander Griend DJ, Walsh PC, Weil CJ, Wender R, Gomella LG: Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017. J Clin Oncol. 2018 Feb 1; 2017 Dec 13. PMID: 29236593

Haas AV, Cong E, Simpson CA, Sukumar N, Deng Y, Insogna KL: Associations among circulating colony-stimulating factor-1, estrogen, and bone mineral density in postmenopausal women: results from a randomized placebo-controlled trial. Menopause. 2018 Feb. PMID: 28816930

Taube JM, Galon J, Sholl LM, Rodig SJ, Cottrell TR, Giraldo NA, Baras AS, Patel SS, Anders RA, Rimm DL, Cimino-Mathews A: Implications of the tumor immune microenvironment for staging and therapeutics. Mod Pathol. 2018 Feb; 2017 Dec 1. PMID: 29192647

Perry RJ, Peng L, Cline GW, Butrico GM, Wang Y, Zhang XM, Rothman DL, Petersen KF, Shulman GI: Publisher Correction: Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA). Nat Commun. 2018 Jan 31; 2018 Jan 31. PMID: 29386503

Hsieh E, Wang Q, Zhang R, Niu X, Xia W, Fraenkel L, Insogna KL, Li J, Smith JS, Zhou C, Qiao YL, Zhang P: Vertebral fractures among breast cancer survivors in China: a cross-sectional study of prevalence and health services gaps. BMC Cancer. 2018 Jan 30; 2018 Jan 30. PMID: 29378534

Budatha M, Zhang J, Zhuang ZW, Yun S, Dahlman JE, Anderson DG, Schwartz MA: Inhibiting Integrin α5 Cytoplasmic Domain Signaling Reduces Atherosclerosis and Promotes Arteriogenesis. J Am Heart Assoc. 2018 Jan 30; 2018 Jan 30. PMID: 29382667

Lee S, Choi J, Mohanty J, Sousa LP, Tome F, Pardon E, Steyaert J, Lemmon MA, Lax I, Schlessinger J: Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling. Nature. 2018 Jan 25; 2018 Jan 17. PMID: 29342135

Ha BH, Boggon TJ: CDC42 binds PAK4 via an extended GTPase-effector interface. Proc Natl Acad Sci U S A. 2018 Jan 16; 2018 Jan 2. PMID: 29295922

Perry RJ, Wang Y, Cline GW, Rabin-Court A, Song JD, Dufour S, Zhang XM, Petersen KF, Shulman GI: Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation. Cell. 2018 Jan 11; 2018 Jan 4. PMID: 29307489

Zwick RK, Guerrero-Juarez CF, Horsley V, Plikus MV: Anatomical, Physiological, and Functional Diversity of Adipose Tissue. Cell Metab. 2018 Jan 9. PMID: 29320711

Perry RJ, Peng L, Cline GW, Wang Y, Rabin-Court A, Song JD, Zhang D, Zhang XM, Nozaki Y, Dufour S, Petersen KF, Shulman GI: Mechanisms by which a Very-Low-Calorie Diet Reverses Hyperglycemia in a Rat Model of Type 2 Diabetes. Cell Metab. 2018 Jan 9; 2017 Nov 9. PMID: 29129786

Smirnova L, Kleinstreuer N, Corvi R, Levchenko A, Fitzpatrick SC, Hartung T: 3S - Systematic, systemic, and systems biology and toxicology. ALTEX. 2018. PMID: 29677694

Stern DF: Keeping Tumors Out of the MAPK Fitness Zone. Cancer Discov. 2018 Jan. PMID: 29311225

Yang Y, Xu C, Liu X, Xu C, Zhang Y, Shen L, Vihinen M, Shen B: NDDVD: an integrated and manually curated Neurodegenerative Diseases Variation Database. Database (Oxford). 2018 Jan 1. PMID: 29688368

Jurczak MJ, Saini S, Ioja S, Costa DK, Udeh N, Zhao X, Whaley JM, Kibbey RG: SGLT2 knockout prevents hyperglycemia and is associated with reduced pancreatic β-cell death in genetically obese mice. Islets. 2018; 2018 Aug 17. PMID: 30118626

Cecchini M, Walther Z, Sklar JL, Bindra RS, Petrylak DP, Eder JP, Goldberg SB: Yale Cancer Center Precision Medicine Tumor Board: two patients, one targeted therapy, different outcomes. Lancet Oncol. 2018 Jan. PMID: 29304353

Cecchini M, Walther Z, Sklar JL, Bindra RS, Petrylak DP, Eder JP, Goldberg SB: Introduction to the Yale Precision Medicine Tumor Board. Lancet Oncol. 2018 Jan. PMID: 29304351

Yu P, Alves TC, Kibbey RG, Simons M: Metabolic Analysis of Lymphatic Endothelial Cells. Methods Mol Biol. 2018. PMID: 30242770

Kolodecik TR, Reed AM, Date K, Shugrue CA, Patel V, Chung SL, Desir GV, Gorelick FS: The serum protein renalase reduces injury in experimental pancreatitis. J Biol Chem. 2017 Dec 22; 2017 Oct 17. PMID: 29042438

Bertacco A, Dehner CA, Caturegli G, D'Amico F, Morotti R, Rodriguez MI, Mulligan DC, Kriegel MA, Geibel JP: Modulation of Intestinal Microbiome Prevents Intestinal Ischemic Injury. Front Physiol. 2017; 2017 Dec 19. PMID: 29311987

Fang JS, Coon BG, Gillis N, Chen Z, Qiu J, Chittenden TW, Burt JM, Schwartz MA, Hirschi KK: Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Nat Commun. 2017 Dec 15; 2017 Dec 15. PMID: 29247167

Hughes LD, Bosurgi L, Ghosh S, Rothlin CV: Chronicles of Cell Death Foretold: Specificities in the Mechanism of Disposal. Front Immunol. 2017; 2017 Dec 11. PMID: 29312294

Janostiak R, Rauniyar N, Lam TT, Ou J, Zhu LJ, Green MR, Wajapeyee N: MELK Promotes Melanoma Growth by Stimulating the NF-κB Pathway. Cell Rep. 2017 Dec 5. PMID: 29212029

Murphy TF, Kirkham C, Gallo MC, Yang Y, Wilding GE, Pettigrew MM: Immunoglobulin A Protease Variants Facilitate Intracellular Survival in Epithelial Cells By Nontypeable Haemophilus influenzae That Persist in the Human Respiratory Tract in Chronic Obstructive Pulmonary Disease. J Infect Dis. 2017 Dec 5. PMID: 28968876

Liu T, Zhou HJ, Min W: ASK family in cardiovascular biology and medicine. Adv Biol Regul. 2017 Dec; 2017 Oct 24. PMID: 29107568

Chagpar AB, Horowitz N, Sanft T, Wilson LD, Silber A, Killelea B, Moran MS, DiGiovanna MP, Hofstatter E, Chung G, Pusztai L, Lannin DR: Discussion of: "Does lymph node status influence adjuvant therapy decision-making in women 70 years of age or older with clinically node negative hormone receptor positive breast cancer?" Am J Surg. 2017 Dec; 2017 Sep 30. PMID: 28987415

Chagpar AB, Horowitz N, Sanft T, Wilson LD, Silber A, Killelea B, Moran MS, DiGiovanna MP, Hofstatter E, Chung G, Pusztai L, Lannin DR: Does lymph node status influence adjuvant therapy decision-making in women 70 years of age or older with clinically node negative hormone receptor positive breast cancer? Am J Surg. 2017 Dec; 2017 Sep 18. PMID: 28939252

Hoang D, Broer N, Sosa JA, Abitbol N, Yao X, Li F, Rivera-Molina F, Toomre DK, Roman SA, Sue G, Kim S, Li AY, Callender GG, Simpson C, Narayan D: Leptin Is Produced by Parathyroid Glands and Stimulates Parathyroid Hormone Secretion. Ann Surg. 2017 Dec. PMID: 27611607

Gettinger S, Choi J, Hastings K, Truini A, Datar I, Sowell R, Wurtz A, Dong W, Cai G, Melnick MA, Du VY, Schlessinger J, Goldberg SB, Chiang A, Sanmamed MF, Melero I, Agorreta J, Montuenga LM, Lifton R, Ferrone S, Kavathas P, Rimm DL, Kaech SM, Schalper K, Herbst RS, Politi K: Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer. Cancer Discov. 2017 Dec; 2017 Oct 12. PMID: 29025772

Katrancha SM, Wu Y, Zhu M, Eipper BA, Koleske AJ, Mains RE: Neurodevelopmental disease-associated de novo mutations and rare sequence variants affect TRIO GDP/GTP exchange factor activity. Hum Mol Genet. 2017 Dec 1. PMID: 28973398

Chai TC, Kudze T: New therapeutic directions to treat underactive bladder. Investig Clin Urol. 2017 Dec; 2017 Dec 19. PMID: 29279882

Dzimitrowicz H, Mougalian S, Storms S, Hurd S, Chagpar AB, Killelea BK, Horowitz NR, Lannin DR, Harigopal M, Hofstatter E, DiGiovanna MP, Adelson KB, Silber A, Abu-Khalaf M, Chung G, Zaheer W, Abdelghany O, Hatzis C, Pusztai L, Sanft TB: Impacts of Early Guideline-Directed 21-Gene Recurrence Score Testing on Adjuvant Therapy Decision Making. J Oncol Pract. 2017 Dec; 2017 Oct 19. PMID: 29048991

Wasserman BE, Carvajal-Hausdorf DE, Ho K, Wong W, Wu N, Chu VC, Lai EW, Weidler JM, Bates M, Neumeister V, Rimm DL: High concordance of a closed-system, RT-qPCR breast cancer assay for HER2 mRNA, compared to clinically determined immunohistochemistry, fluorescence in situ hybridization, and quantitative immunofluorescence. Lab Invest. 2017 Dec; 2017 Sep 11. PMID: 28892092

Shapiro LP, Omar MH, Koleske AJ, Gourley SL: Corticosteroid-induced dendrite loss and behavioral deficiencies can be blocked by activation of Abl2/Arg kinase. Mol Cell Neurosci. 2017 Dec; 2017 Oct 26. PMID: 29107098

Carlyle BC, Kitchen RR, Kanyo JE, Voss EZ, Pletikos M, Sousa AMM, Lam TT, Gerstein MB, Sestan N, Nairn AC: A multiregional proteomic survey of the postnatal human brain. Nat Neurosci. 2017 Dec; 2017 Nov 13. PMID: 29184206

Li X, Tao Y, Murphy JW, Scherer AN, Lam TT, Marshall AG, Koleske AJ, Boggon TJ: The repeat region of cortactin is intrinsically disordered in solution. Sci Rep. 2017 Dec 1; 2017 Dec 1. PMID: 29196701

Lawan A, Bennett AM: Mitogen-Activated Protein Kinase Regulation in Hepatic Metabolism. Trends Endocrinol Metab. 2017 Dec; 2017 Nov 8. PMID: 29128158

Xue Q, Bettini E, Paczkowski P, Ng C, Kaiser A, McConnell T, Kodrasi O, Quigley MF, Heath J, Fan R, Mackay S, Dudley ME, Kassim SH, Zhou J: Single-cell multiplexed cytokine profiling of CD19 CAR-T cells reveals a diverse landscape of polyfunctional antigen-specific response. J Immunother Cancer. 2017 Nov 21; 2017 Nov 21. PMID: 29157295

Petrylak DP, de Wit R, Chi KN, Drakaki A, Sternberg CN, Nishiyama H, Castellano D, Hussain S, Fléchon A, Bamias A, Yu EY, van der Heijden MS, Matsubara N, Alekseev B, Necchi A, Géczi L, Ou YC, Coskun HS, Su WP, Hegemann M, Percent IJ, Lee JL, Tucci M, Semenov A, Laestadius F, Peer A, Tortora G, Safina S, Del Muro XG, Rodriguez-Vida A, Cicin I, Harputluoglu H, Widau RC, Liepa AM, Walgren RA, Hamid O, Zimmermann AH, Bell-McGuinn KM, Powles T, RANGE study investigators.: Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): a randomised, double-blind, phase 3 trial. Lancet. 2017 Nov 18; 2017 Sep 12. PMID: 28916371

Yao GQ, Troiano N, Simpson CA, Insogna KL: Selective deletion of the soluble Colony-Stimulating Factor 1 isoform in vivo prevents estrogen-deficiency bone loss in mice. Bone Res. 2017; 2017 Nov 14. PMID: 29152381

Budenholzer L, Cheng CL, Li Y, Hochstrasser M: Proteasome Structure and Assembly. J Mol Biol. 2017 Nov 10; 2017 Jun 3. PMID: 28583440

Lagendijk AK, Gomez GA, Baek S, Hesselson D, Hughes WE, Paterson S, Conway DE, Belting HG, Affolter M, Smith KA, Schwartz MA, Yap AS, Hogan BM: Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish. Nat Commun. 2017 Nov 10; 2017 Nov 10. PMID: 29123087

Mo ES, Cheng Q, Reshetnyak AV, Schlessinger J, Nicoli S: Alk and Ltk ligands are essential for iridophore development in zebrafish mediated by the receptor tyrosine kinase Ltk. Proc Natl Acad Sci U S A. 2017 Nov 7; 2017 Oct 23. PMID: 29078341

Hendry S, Salgado R, Gevaert T, Russell PA, John T, Thapa B, Christie M, van de Vijver K, Estrada MV, Gonzalez-Ericsson PI, Sanders M, Solomon B, Solinas C, Van den Eynden GGGM, Allory Y, Preusser M, Hainfellner J, Pruneri G, Vingiani A, Demaria S, Symmans F, Nuciforo P, Comerma L, Thompson EA, Lakhani S, Kim SR, Schnitt S, Colpaert C, Sotiriou C, Scherer SJ, Ignatiadis M, Badve S, Pierce RH, Viale G, Sirtaine N, Penault-Llorca F, Sugie T, Fineberg S, Paik S, Srinivasan A, Richardson A, Wang Y, Chmielik E, Brock J, Johnson DB, Balko J, Wienert S, Bossuyt V, Michiels S, Ternes N, Burchardi N, Luen SJ, Savas P, Klauschen F, Watson PH, Nelson BH, Criscitiello C, O'Toole S, Larsimont D, de Wind R, Curigliano G, André F, Lacroix-Triki M, van de Vijver M, Rojo F, Floris G, Bedri S, Sparano J, Rimm D, Nielsen T, Kos Z, Hewitt S, Singh B, Farshid G, Loibl S, Allison KH, Tung N, Adams S, Willard-Gallo K, Horlings HM, Gandhi L, Moreira A, Hirsch F, Dieci MV, Urbanowicz M, Brcic I, Korski K, Gaire F, Koeppen H, Lo A, Giltnane J, Rebelatto MC, Steele KE, Zha J, Emancipator K, Juco JW, Denkert C, Reis-Filho J, Loi S, Fox SB: Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors. Adv Anat Pathol. 2017 Nov. PMID: 28777143

Allam A, Krauthammer M: PySeqLab: an open source Python package for sequence labeling and segmentation. Bioinformatics. 2017 Nov 1. PMID: 29036277

Chai TC: Re: Incontinence Medication Response Relates to the Female Urinary Microbiota. Eur Urol. 2017 Nov; 2017 Jun 23. PMID: 28648367

Bosurgi L, Hughes LD, Rothlin CV, Ghosh S: Death begets a new beginning. Immunol Rev. 2017 Nov. PMID: 29027219

Xu Y, Toomre DK, Bogan JS, Hao M: Excess cholesterol inhibits glucose-stimulated fusion pore dynamics in insulin exocytosis. J Cell Mol Med. 2017 Nov; 2017 May 25. PMID: 28544529

Mougalian SS, Epstein LN, Jhaveri AP, Han G, Abu-Khalaf M, Hofstatter EW, DiGiovanna MP, Silber ALM, Adelson K, Pusztai L, Gross CP: Bidirectional Text Messaging to Monitor Endocrine Therapy Adherence and Patient-Reported Outcomes in Breast Cancer. JCO Clin Cancer Inform. 2017 Nov. PMID: 30657377

Rübsam M, Mertz AF, Kubo A, Marg S, Jüngst C, Goranci-Buzhala G, Schauss AC, Horsley V, Dufresne ER, Moser M, Ziegler W, Amagai M, Wickström SA, Niessen CM: E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning. Nat Commun. 2017 Nov 1; 2017 Nov 1. PMID: 29093447

Price NL, Rotllan N, Canfrán-Duque A, Zhang X, Pati P, Arias N, Moen J, Mayr M, Ford DA, Baldán Á, Suárez Y, Fernández-Hernando C: Genetic Dissection of the Impact of miR-33a and miR-33b during the Progression of Atherosclerosis. Cell Rep. 2017 Oct 31. PMID: 29091769

Omar MH, Kerrisk Campbell M, Xiao X, Zhong Q, Brunken WJ, Miner JH, Greer CA, Koleske AJ: CNS Neurons Deposit Laminin α5 to Stabilize Synapses. Cell Rep. 2017 Oct 31. PMID: 29091766

Vijayakumar A, Aryal P, Wen J, Syed I, Vazirani RP, Moraes-Vieira PM, Camporez JP, Gallop MR, Perry RJ, Peroni OD, Shulman GI, Saghatelian A, McGraw TE, Kahn BB: Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport. Cell Rep. 2017 Oct 24. PMID: 29069585

Ferrandino G, Kaspari RR, Spadaro O, Reyna-Neyra A, Perry RJ, Cardone R, Kibbey RG, Shulman GI, Dixit VD, Carrasco N: Pathogenesis of hypothyroidism-induced NAFLD is driven by intra- and extrahepatic mechanisms. Proc Natl Acad Sci U S A. 2017 Oct 24; 2017 Oct 10. PMID: 29073114

Freed DM, Bessman NJ, Kiyatkin A, Salazar-Cavazos E, Byrne PO, Moore JO, Valley CC, Ferguson KM, Leahy DJ, Lidke DS, Lemmon MA: EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics. Cell. 2017 Oct 19; 2017 Oct 5. PMID: 28988771

Min K, Lawan A, Bennett AM: Loss of MKP-5 promotes myofiber survival by activating STAT3/Bcl-2 signaling during regenerative myogenesis. Skelet Muscle. 2017 Oct 18; 2017 Oct 18. PMID: 29047406

Carvajal-Hausdorf DE, Mani N, Velcheti V, Schalper KA, Rimm DL: Objective measurement and clinical significance of IDO1 protein in hormone receptor-positive breast cancer. J Immunother Cancer. 2017 Oct 17; 2017 Oct 17. PMID: 29037255

Miller CJ, Muftuoglu Y, Turk BE: A high throughput assay to identify substrate-selective inhibitors of the ERK protein kinases. Biochem Pharmacol. 2017 Oct 15; 2017 Jun 21. PMID: 28647489

Ascierto PA, Daniele B, Hammers H, Hirsh V, Kim J, Licitra L, Nanda R, Pignata S: Perspectives in immunotherapy: meeting report from the "Immunotherapy Bridge", Napoli, November 30th 2016. J Transl Med. 2017 Oct 11; 2017 Oct 11. PMID: 29020960

Shah SR, David JM, Tippens ND, Mohyeldin A, Martinez-Gutierrez JC, Ganaha S, Schiapparelli P, Hamilton DH, Palena C, Levchenko A, Quiñones-Hinojosa A: Brachyury-YAP Regulatory Axis Drives Stemness and Growth in Cancer. Cell Rep. 2017 Oct 10. PMID: 29020634

Khamphaya T, Chukijrungroat N, Saengsirisuwan V, Mitchell-Richards KA, Robert ME, Mennone A, Ananthanarayanan M, Nathanson MH, Weerachayaphorn J: Nonalcoholic fatty liver disease impairs expression of the type II inositol 1,4,5-trisphosphate receptor. Hepatology. 2017 Oct 10; 2017 Oct 10. PMID: 29023819

Perry RJ, Peng L, Cline GW, Butrico GM, Wang Y, Zhang XM, Rothman DL, Petersen KF, Shulman GI: Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA). Nat Commun. 2017 Oct 6; 2017 Oct 6. PMID: 28986525

Thompson AD, Bewersdorf J, Toomre D, Schepartz A: HIDE Probes: A New Toolkit for Visualizing Organelle Dynamics, Longer and at Super-Resolution. Biochemistry. 2017 Oct 3; 2017 Aug 9. PMID: 28792749

Chagpar AB, Hatzis C, Pusztai L, DiGiovanna MP, Moran M, Mougalian S, Sanft T, Evans S, Hofstatter E, Wilson LD, Lannin DR: Association of LN Evaluation with Survival in Women Aged 70 Years or Older With Clinically Node-Negative Hormone Receptor Positive Breast Cancer. Ann Surg Oncol. 2017 Oct; 2017 Aug 1. PMID: 28766195

Gil Del Alcazar CR, Huh SJ, Ekram MB, Trinh A, Liu LL, Beca F, Zi X, Kwak M, Bergholtz H, Su Y, Ding L, Russnes HG, Richardson AL, Babski K, Min Hui Kim E, McDonnell CH 3rd, Wagner J, Rowberry R, Freeman GJ, Dillon D, Sorlie T, Coussens LM, Garber JE, Fan R, Bobolis K, Allred DC, Jeong J, Park SY, Michor F, Polyak K: Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition. Cancer Discov. 2017 Oct; 2017 Jun 26. PMID: 28652380

Yao C, Yu KP, Philbrick W, Sun BH, Simpson C, Zhang C, Insogna K: Breast cancer-associated gene 3 interacts with Rac1 and augments NF-κB signaling in vitro, but has no effect on RANKL-induced bone resorption in vivo. Int J Mol Med. 2017 Oct; 2017 Aug 4. PMID: 28791343

Theodosakis N, Micevic G, Langdon CG, Ventura A, Means R, Stern DF, Bosenberg MW: p90RSK Blockade Inhibits Dual BRAF and MEK Inhibitor-Resistant Melanoma by Targeting Protein Synthesis. J Invest Dermatol. 2017 Oct; 2017 Jun 7. PMID: 28599981

Kamat AM, Bellmunt J, Galsky MD, Konety BR, Lamm DL, Langham D, Lee CT, Milowsky MI, O'Donnell MA, O'Donnell PH, Petrylak DP, Sharma P, Skinner EC, Sonpavde G, Taylor JA 3rd, Abraham P, Rosenberg JE: Erratum to: Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of bladder carcinoma. J Immunother Cancer. 2017 Sep 28; 2017 Sep 28. PMID: 28962591

Pelekanou V, Carvajal-Hausdorf DE, Altan M, Wasserman B, Carvajal-Hausdorf C, Wimberly H, Brown J, Lannin D, Pusztai L, Rimm DL: Erratum to: Effect of neoadjuvant chemotherapy on tumor-infiltrating lymphocytes and PD-L1 expression in breast cancer and its clinical significance. Breast Cancer Res. 2017 Sep 25; 2017 Sep 25. PMID: 28946899

Lee H, Koh BH, Peri LE, Corrigan RD, Lee HT, George NE, Bhetwal BP, Xie Y, Perrino BA, Chai TC, Sanders KM, Koh SD: Premature contractions of the bladder are suppressed by interactions between TRPV4 and SK3 channels in murine detrusor PDGFRα+ cells. Sci Rep. 2017 Sep 25; 2017 Sep 25. PMID: 28947806

Park J, Yang J, Wenzel AT, Ramachandran A, Lee WJ, Daniels JC, Kim J, Martinez-Escala E, Amankulor N, Pro B, Guitart J, Mendillo ML, Savas JN, Boggon TJ, Choi J: Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E). Blood. 2017 Sep 21; 2017 Jul 10. PMID: 28694326

Yin M, Zhou HJ, Zhang J, Lin C, Li H, Li X, Li Y, Zhang H, Breckenridge DG, Ji W, Min W: ASK1-dependent endothelial cell activation is critical in ovarian cancer growth and metastasis. JCI Insight. 2017 Sep 21; 2017 Sep 21. PMID: 28931753

Huet-Calderwood C, Rivera-Molina F, Iwamoto DV, Kromann EB, Toomre D, Calderwood DA: Novel ecto-tagged integrins reveal their trafficking in live cells. Nat Commun. 2017 Sep 18; 2017 Sep 18. PMID: 28924207

Stiegler AL, Boggon TJ: p190RhoGAP proteins contain pseudoGTPase domains. Nat Commun. 2017 Sep 11; 2017 Sep 11. PMID: 28894085

Rivera-Gonzalez GC, Shook BA, Horsley V: PDGFA regulation of dermal adipocyte stem cells. Stem Cell Investig. 2017; 2017 Sep 7. PMID: 29057244

Dunlop MH, Ernst AM, Schroeder LK, Toomre DK, Lavieu G, Rothman JE: Land-locked mammalian Golgi reveals cargo transport between stable cisternae. Nat Commun. 2017 Sep 5; 2017 Sep 5. PMID: 28874656

Hendry S, Salgado R, Gevaert T, Russell PA, John T, Thapa B, Christie M, van de Vijver K, Estrada MV, Gonzalez-Ericsson PI, Sanders M, Solomon B, Solinas C, Van den Eynden GGGM, Allory Y, Preusser M, Hainfellner J, Pruneri G, Vingiani A, Demaria S, Symmans F, Nuciforo P, Comerma L, Thompson EA, Lakhani S, Kim SR, Schnitt S, Colpaert C, Sotiriou C, Scherer SJ, Ignatiadis M, Badve S, Pierce RH, Viale G, Sirtaine N, Penault-Llorca F, Sugie T, Fineberg S, Paik S, Srinivasan A, Richardson A, Wang Y, Chmielik E, Brock J, Johnson DB, Balko J, Wienert S, Bossuyt V, Michiels S, Ternes N, Burchardi N, Luen SJ, Savas P, Klauschen F, Watson PH, Nelson BH, Criscitiello C, O'Toole S, Larsimont D, de Wind R, Curigliano G, André F, Lacroix-Triki M, van de Vijver M, Rojo F, Floris G, Bedri S, Sparano J, Rimm D, Nielsen T, Kos Z, Hewitt S, Singh B, Farshid G, Loibl S, Allison KH, Tung N, Adams S, Willard-Gallo K, Horlings HM, Gandhi L, Moreira A, Hirsch F, Dieci MV, Urbanowicz M, Brcic I, Korski K, Gaire F, Koeppen H, Lo A, Giltnane J, Rebelatto MC, Steele KE, Zha J, Emancipator K, Juco JW, Denkert C, Reis-Filho J, Loi S, Fox SB: Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma In Situ, Metastatic Tumor Deposits and Areas for Further Research. Adv Anat Pathol. 2017 Sep. PMID: 28777142

Zhu X, Ding S, Qiu C, Shi Y, Song L, Wang Y, Wang Y, Li J, Wang Y, Sun Y, Qin L, Chen J, Simons M, Min W, Yu L: SUMOylation Negatively Regulates Angiogenesis by Targeting Endothelial NOTCH Signaling. Circ Res. 2017 Sep 1; 2017 Jul 31. PMID: 28760777

Altan M, Pelekanou V, Schalper KA, Toki M, Gaule P, Syrigos K, Herbst RS, Rimm DL: B7-H3 Expression in NSCLC and Its Association with B7-H4, PD-L1 and Tumor-Infiltrating Lymphocytes. Clin Cancer Res. 2017 Sep 1; 2017 May 24. PMID: 28539467

Canfrán-Duque A, Rotllan N, Zhang X, Fernández-Fuertes M, Ramírez-Hidalgo C, Araldi E, Daimiel L, Busto R, Fernández-Hernando C, Suárez Y: Macrophage deficiency of miR-21 promotes apoptosis, plaque necrosis, and vascular inflammation during atherogenesis. EMBO Mol Med. 2017 Sep. PMID: 28674080

Wu CC, Econs MJ, DiMeglio LA, Insogna KL, Levine MA, Orchard PJ, Miller WP, Petryk A, Rush ET, Shoback DM, Ward LM, Polgreen LE: Diagnosis and Management of Osteopetrosis: Consensus Guidelines From the Osteopetrosis Working Group. J Clin Endocrinol Metab. 2017 Sep 1. PMID: 28655174

Chai TC: Mesh Sling Removals: Why, When, How and Consequences. J Urol. 2017 Sep; 2017 Jun 20. PMID: 28641082

Wang N, Cheng J, Fan R, Lu J: Capture, amplification, and global profiling of microRNAs from low quantities of whole cell lysate. Analyst. 2017 Aug 21. PMID: 28765841

Thompson AD, Omar MH, Rivera-Molina F, Xi Z, Koleske AJ, Toomre DK, Schepartz A: Long-Term Live-Cell STED Nanoscopy of Primary and Cultured Cells with the Plasma Membrane HIDE Probe DiI-SiR. Angew Chem Int Ed Engl. 2017 Aug 21; 2017 Jul 24. PMID: 28679029

Nagarajan A, Dogra SK, Sun L, Gandotra N, Ho T, Cai G, Cline G, Kumar P, Cowles RA, Wajapeyee N: Paraoxonase 2 Facilitates Pancreatic Cancer Growth and Metastasis by Stimulating GLUT1-Mediated Glucose Transport. Mol Cell. 2017 Aug 17; 2017 Aug 10. PMID: 28803777

Brown S, Pineda CM, Xin T, Boucher J, Suozzi KC, Park S, Matte-Martone C, Gonzalez DG, Rytlewski J, Beronja S, Greco V: Correction of aberrant growth preserves tissue homeostasis. Nature. 2017 Aug 17; 2017 Aug 2. PMID: 28783732

Fu M, Yang X: The sweet tooth of the circadian clock. Biochem Soc Trans. 2017 Aug 15; 2017 Jul 3. PMID: 28673939

Ruan HB, Ma Y, Torres S, Zhang B, Feriod C, Heck RM, Qian K, Fu M, Li X, Nathanson MH, Bennett AM, Nie Y, Ehrlich BE, Yang X: Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation. Genes Dev. 2017 Aug 15; 2017 Sep 13. PMID: 28903979

Roberts NA, Adams BD, McCarthy NI, Tooze RM, Parnell SM, Anderson G, Kaech SM, Horsley V: Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity. J Immunol. 2017 Aug 15; 2017 Jul 12. PMID: 28701508

Kamat AM, Bellmunt J, Galsky MD, Konety BR, Lamm DL, Langham D, Lee CT, Milowsky MI, O'Donnell MA, O'Donnell PH, Petrylak DP, Sharma P, Skinner EC, Sonpavde G, Taylor JA 3rd, Abraham P, Rosenberg JE: Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of bladder carcinoma. J Immunother Cancer. 2017 Aug 15; 2017 Aug 15. PMID: 28807024

Pelekanou V, Carvajal-Hausdorf DE, Altan M, Wasserman B, Carvajal-Hausdorf C, Wimberly H, Brown J, Lannin D, Pusztai L, Rimm DL: Effect of neoadjuvant chemotherapy on tumor-infiltrating lymphocytes and PD-L1 expression in breast cancer and its clinical significance. Breast Cancer Res. 2017 Aug 7; 2017 Aug 7. PMID: 28784153

Advani G, Lim YC, Catimel B, Lio DSS, Ng NLY, Chüeh AC, Tran M, Anasir MI, Verkade H, Zhu HJ, Turk BE, Smithgall TE, Ang CS, Griffin M, Cheng HC: Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine. Cell Commun Signal. 2017 Aug 7; 2017 Aug 7. PMID: 28784162

Sivarapatna A, Ghaedi M, Xiao Y, Han E, Aryal B, Zhou J, Fernandez-Hernando C, Qyang Y, Hirschi KK, Niklason LE: Engineered Microvasculature in PDMS Networks Using Endothelial Cells Derived from Human Induced Pluripotent Stem Cells. Cell Transplant. 2017 Aug. PMID: 28901188

Kluger HM, Zito CR, Turcu G, Baine MK, Zhang H, Adeniran A, Sznol M, Rimm DL, Kluger Y, Chen L, Cohen JV, Jilaveanu LB: PD-L1 Studies Across Tumor Types, Its Differential Expression and Predictive Value in Patients Treated with Immune Checkpoint Inhibitors. Clin Cancer Res. 2017 Aug 1; 2017 Feb 21. PMID: 28223273

Kim JD, Toda C, Ramírez CM, Fernández-Hernando C, Diano S: Hypothalamic Ventromedial Lin28a Enhances Glucose Metabolism in Diet-Induced Obesity. Diabetes. 2017 Aug; 2017 May 26. PMID: 28550108

Rimm DL, Han G, Taube JM, Yi ES, Bridge JA, Flieder DB, Homer R, West WW, Wu H, Roden AC, Fujimoto J, Yu H, Anders R, Kowalewski A, Rivard C, Rehman J, Batenchuk C, Burns V, Hirsch FR, Wistuba II: A Prospective, Multi-institutional, Pathologist-Based Assessment of 4 Immunohistochemistry Assays for PD-L1 Expression in Non-Small Cell Lung Cancer. JAMA Oncol. 2017 Aug 1. PMID: 28278348

Takakura H, Zhang Y, Erdmann RS, Thompson AD, Lin Y, McNellis B, Rivera-Molina F, Uno SN, Kamiya M, Urano Y, Rothman JE, Bewersdorf J, Schepartz A, Toomre D: Long time-lapse nanoscopy with spontaneously blinking membrane probes. Nat Biotechnol. 2017 Aug; 2017 Jul 3. PMID: 28671662

Petrylak DP, Crawford ED: Biomarkers for the Management of Castration-Resistant Prostate Cancer: We Are Not There Yet. Target Oncol. 2017 Aug. PMID: 28620691

Helou E, Grant M, Landry M, Wu X, Morrow JS, Malinis MF: Fatal case of cutaneous-sparing orolaryngeal zoster in a renal transplant recipient. Transpl Infect Dis. 2017 Aug; 2017 Jun 1. PMID: 28401625

Glass LN, Swapna G, Chavadi SS, Tufariello JM, Mi K, Drumm JE, Lam TT, Zhu G, Zhan C, Vilchéze C, Arcos J, Chen Y, Bi L, Mehta S, Porcelli SA, Almo SC, Yeh SR, Jacobs WR Jr, Torrelles JB, Chan J: Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (ABC) transporter Rv1747 to regulate mycobacterial growth. PLoS Pathog. 2017 Jul; 2017 Jul 28. PMID: 28753640

Yang Y, Lin C: Directing reconfigurable DNA nanoarrays. Science. 2017 Jul 28. PMID: 28751594

Wadia R, Shifman M, Levin FL, Marenco L, Brandt CA, Cheung KH, Taddei T, Krauthammer M: A Clinical Decision Support System for Monitoring Post-Colonoscopy Patient Follow-Up and Scheduling. AMIA Jt Summits Transl Sci Proc. 2017; 2017 Jul 26. PMID: 28815144

Tan S, Feng B, Yin M, Zhou HJ, Lou G, Ji W, Li Y, Min W: Stromal Senp1 promotes mouse early folliculogenesis by regulating BMP4 expression. Cell Biosci. 2017; 2017 Jul 25. PMID: 28770041

Conway DE, Coon BG, Budatha M, Arsenovic PT, Orsenigo F, Wessel F, Zhang J, Zhuang Z, Dejana E, Vestweber D, Schwartz MA: VE-Cadherin Phosphorylation Regulates Endothelial Fluid Shear Stress Responses through the Polarity Protein LGN. Curr Biol. 2017 Jul 24; 2017 Jul 14. PMID: 28712573

Uribe DJ, Mandell EK, Watson A, Martinez JD, Leighton JA, Ghosh S, Rothlin CV: The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer. PLoS One. 2017; 2017 Jul 20. PMID: 28727830

Klein ZA, Takahashi H, Ma M, Stagi M, Zhou M, Lam TT, Strittmatter SM: Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice. Neuron. 2017 Jul 19. PMID: 28728022

Alvarado D, Ligon GF, Lillquist JS, Seibel SB, Wallweber G, Neumeister VM, Rimm DL, McMahon G, LaVallee TM: ErbB activation signatures as potential biomarkers for anti-ErbB3 treatment in HNSCC. PLoS One. 2017; 2017 Jul 19. PMID: 28723928

Park J, Holmes WR, Lee SH, Kim HN, Kim DH, Kwak MK, Wang CJ, Edelstein-Keshet L, Levchenko A: Mechanochemical feedback underlies coexistence of qualitatively distinct cell polarity patterns within diverse cell populations. Proc Natl Acad Sci U S A. 2017 Jul 11; 2017 Jun 27. PMID: 28655842

Ronau JA, Hochstrasser M: The DUB blade goes snicker-snack: Novel ubiquitin cleavage by a Legionella effector protein. Cell Res. 2017 Jul; 2017 Jun 2. PMID: 28574056

Abulizi A, Perry RJ, Camporez JPG, Jurczak MJ, Petersen KF, Aspichueta P, Shulman GI: A controlled-release mitochondrial protonophore reverses hypertriglyceridemia, nonalcoholic steatohepatitis, and diabetes in lipodystrophic mice. FASEB J. 2017 Jul; 2017 Mar 22. PMID: 28330852

Wang Y, Safirstein R, Velazquez H, Guo XJ, Hollander L, Chang J, Chen TM, Mu JJ, Desir GV: Extracellular renalase protects cells and organs by outside-in signalling. J Cell Mol Med. 2017 Jul; 2017 Feb 26. PMID: 28238213

Chai TC, Asfaw TS, Baker JE, Clarkson B, Coleman P, Hoffstetter S, Konkel K, Lavender M, Nair S, Norton J, Subak L, Visco A, Star RA, Bavendam T: Future Directions of Research and Care for Urinary Incontinence: Findings from the National Institute of Diabetes and Digestive and Kidney Diseases Summit on Urinary Incontinence Clinical Research in Women. J Urol. 2017 Jul; 2017 Mar 9. PMID: 28286067

Suda K, Rozeboom L, Rivard CJ, Yu H, Ellison K, Melnick MAC, Hinz TK, Chan D, Heasley LE, Politi K, Mitsudomi T, Hirsch FR: Therapy-induced E-cadherin downregulation alters expression of programmed death ligand-1 in lung cancer cells. Lung Cancer. 2017 Jul; 2017 Apr 19. PMID: 28577937

Chen Y, Lee H, Tong H, Schwartz M, Zhu C: Force regulated conformational change of integrin αVβ3. Matrix Biol. 2017 Jul; 2016 Jul 14. PMID: 27423389

Moore LM, England A, Ehrlich BE, Rimm DL: Calcium Sensor, NCS-1, Promotes Tumor Aggressiveness and Predicts Patient Survival. Mol Cancer Res. 2017 Jul; 2017 Mar 8. PMID: 28275088

Yang X, Qian K: Protein O-GlcNAcylation: emerging mechanisms and functions. Nat Rev Mol Cell Biol. 2017 Jul; 2017 May 10. PMID: 28488703

Almadanim MC, Alexandre BM, Rosa MTG, Sapeta H, Leitão AE, Ramalho JC, Lam TT, Negrão S, Abreu IA, Oliveira MM: Rice calcium-dependent protein kinase OsCPK17 targets plasma membrane intrinsic protein and sucrose-phosphate synthase and is required for a proper cold stress response. Plant Cell Environ. 2017 Jul; 2017 Mar 2. PMID: 28102545

Williams KR, Colangelo CM, Hou L, Chung L, Belcher JM, Abbott T, Hall IE, Zhao H, Cantley LG, Parikh CR: Use of a Targeted Urine Proteome Assay (TUPA) to identify protein biomarkers of delayed recovery after kidney transplant. Proteomics Clin Appl. 2017 Jul; 2017 Mar 31. PMID: 28261998

Araldi E, Fernández-Fuertes M, Canfrán-Duque A, Tang W, Cline GW, Madrigal-Matute J, Pober JS, Lasunción MA, Wu D, Fernández-Hernando C, Suárez Y: Lanosterol Modulates TLR4-Mediated Innate Immune Responses in Macrophages. Cell Rep. 2017 Jun 27. PMID: 28658622

Klein MI, Stern DF, Zhao H: GRAPE: a pathway template method to characterize tissue-specific functionality from gene expression profiles. BMC Bioinformatics. 2017 Jun 26; 2017 Jun 26. PMID: 28651562

Zhang Z, Yang Y, Pincet F, Llaguno MC, Lin C: Placing and shaping liposomes with reconfigurable DNA nanocages. Nat Chem. 2017 Jun 23. PMID: 28644472

Goffredo M, Santoro N, Tricò D, Giannini C, D'Adamo E, Zhao H, Peng G, Yu X, Lam TT, Pierpont B, Caprio S, Herzog RI: A Branched-Chain Amino Acid-Related Metabolic Signature Characterizes Obese Adolescents with Non-Alcoholic Fatty Liver Disease. Nutrients. 2017 Jun 22; 2017 Jun 22. PMID: 28640216

Bottanelli F, Kilian N, Ernst AM, Rivera-Molina F, Schroeder LK, Kromann EB, Lessard MD, Erdmann RS, Schepartz A, Baddeley D, Bewersdorf J, Toomre D, Rothman JE: A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi. Mol Biol Cell. 2017 Jun 15; 2017 Apr 20. PMID: 28428254

Musante V, Li L, Kanyo J, Lam TT, Colangelo CM, Cheng SK, Brody AH, Greengard P, Le Novère N, Nairn AC: Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition. Elife. 2017 Jun 14; 2017 Jun 14. PMID: 28613156

Cai Y, Liu Y, Culhane KJ, DeVree BT, Yang Y, Sunahara RK, Yan ECY: Purification of family B G protein-coupled receptors using nanodiscs: Application to human glucagon-like peptide-1 receptor. PLoS One. 2017; 2017 Jun 13. PMID: 28609478

Bosurgi L, Cao YG, Cabeza-Cabrerizo M, Tucci A, Hughes LD, Kong Y, Weinstein JS, Licona-Limon P, Schmid ET, Pelorosso F, Gagliani N, Craft JE, Flavell RA, Ghosh S, Rothlin CV: Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells. Science. 2017 Jun 9; 2017 May 11. PMID: 28495875

Chen C, Li L, Zhou HJ, Min W: The Role of NOX4 and TRX2 in Angiogenesis and Their Potential Cross-Talk. Antioxidants (Basel). 2017 Jun 8; 2017 Jun 8. PMID: 28594389

Srivastava R, Mannam P, Rauniyar N, Lam TT, Luo R, Lee PJ, Srivastava A: Proteomics data on MAP Kinase Kinase 3 knock out bone marrow derived macrophages exposed to cigarette smoke extract. Data Brief. 2017 Aug; 2017 Jun 7. PMID: 28653025

Rauniyar N, Peng G, Lam TT, Zhao H, Mor G, Williams KR: Data-Independent Acquisition and Parallel Reaction Monitoring Mass Spectrometry Identification of Serum Biomarkers for Ovarian Cancer. Biomark Insights. 2017; 2017 Jun 5. PMID: 28615921

Horsley V, Naik S: Tregs Expand the Skin Stem Cell Niche. Dev Cell. 2017 Jun 5. PMID: 28586641

Han L, Wu HJ, Zhu H, Kim KY, Marjani SL, Riester M, Euskirchen G, Zi X, Yang J, Han J, Snyder M, Park IH, Irizarry R, Weissman SM, Michor F, Fan R, Pan X: Bisulfite-independent analysis of CpG island methylation enables genome-scale stratification of single cells. Nucleic Acids Res. 2017 Jun 2. PMID: 28126923

Shams-White MM, Chung M, Du M, Fu Z, Insogna KL, Karlsen MC, LeBoff MS, Shapses SA, Sackey J, Wallace TC, Weaver CM: Dietary protein and bone health: a systematic review and meta-analysis from the National Osteoporosis Foundation. Am J Clin Nutr. 2017 Jun; 2017 Apr 12. PMID: 28404575

Petrylak DP: Immunotherapy: The Wave of the Future in Bladder Cancer? Clin Genitourin Cancer. 2017 Jun. PMID: 28633756

Aryal B, Singh AK, Rotllan N, Price N, Fernández-Hernando C: MicroRNAs and lipid metabolism. Curr Opin Lipidol. 2017 Jun. PMID: 28333713

AlKukhun A, Caturegli G, Munoz-Abraham AS, Judeeba S, Patron-Lozano R, Morotti R, Rodriguez-Davalos MI, Geibel JP: Use of Fluorescein Isothiocyanate-Inulin as a Marker for Intestinal Ischemic Injury. J Am Coll Surg. 2017 Jun; 2016 Dec 23. PMID: 28017811

Langdon CG, Platt JT, Means RE, Iyidogan P, Mamillapalli R, Klein M, Held MA, Lee JW, Koo JS, Hatzis C, Hochster HS, Stern DF: Combinatorial Screening of Pancreatic Adenocarcinoma Reveals Sensitivity to Drug Combinations Including Bromodomain Inhibitor Plus Neddylation Inhibitor. Mol Cancer Ther. 2017 Jun; 2017 Mar 14. PMID: 28292938

Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, Song L, Zhou X, Chen J, Zhou H, Zhang H, Tellides G, Min W, Yu L: The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. Nat Commun. 2017 Jun 1; 2017 Jun 1. PMID: 28569748

Crawford ED, Petrylak DP, Shore N, Saad F, Slovin SF, Vogelzang NJ, Keane TE, Koo PJ, Gomella LG, O'Sullivan JM, Tombal B, Concepcion RS, Sieber P, Stone NN, Finkelstein SE, Yu EY, Prostate Cancer Radiographic Assessments for Detection of Advanced Recurrence (RADAR II) Group.: The Role of Therapeutic Layering in Optimizing Treatment for Patients With Castration-resistant Prostate Cancer (Prostate Cancer Radiographic Assessments for Detection of Advanced Recurrence II). Urology. 2017 Jun; 2017 Mar 14. PMID: 28302580

Jayatilaka H, Tyle P, Chen JJ, Kwak M, Ju J, Kim HJ, Lee JSH, Wu PH, Gilkes DM, Fan R, Wirtz D: Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration. Nat Commun. 2017 May 26; 2017 May 26. PMID: 28548090

Sun Y, Yang Y, Galvin VC, Yang S, Arnsten AF, Wang M: Nicotinic α4β2 Cholinergic Receptor Influences on Dorsolateral Prefrontal Cortical Neuronal Firing during a Working Memory Task. J Neurosci. 2017 May 24; 2017 Apr 27. PMID: 28450546

Nishimura S, Mishra-Gorur K, Park J, Surovtseva YV, Sebti SM, Levchenko A, Louvi A, Gunel M: Combined HMG-COA reductase and prenylation inhibition in treatment of CCM. Proc Natl Acad Sci U S A. 2017 May 23; 2017 May 12. PMID: 28500274

Chen C, Nimlamool W, Miller CJ, Lou HJ, Turk BE: Rational Redesign of a Functional Protein Kinase-Substrate Interaction. ACS Chem Biol. 2017 May 19; 2017 Mar 29. PMID: 28314095

Puleo DE, Kucera K, Hammarén HM, Ungureanu D, Newton AS, Silvennoinen O, Jorgensen WL, Schlessinger J: Identification and Characterization of JAK2 Pseudokinase Domain Small Molecule Binders. ACS Med Chem Lett. 2017 Jun 8; 2017 May 17. PMID: 28626521

Newton AS, Deiana L, Puleo DE, Cisneros JA, Cutrona KJ, Schlessinger J, Jorgensen WL: JAK2 JH2 Fluorescence Polarization Assay and Crystal Structures for Complexes with Three Small Molecules. ACS Med Chem Lett. 2017 Jun 8; 2017 May 17. PMID: 28626520

Iwakiri Y, Nathanson MH: Alcohol and calcium make a potent cocktail. J Physiol. 2017 May 15; 2017 Apr 18. PMID: 28295353

Rosenberg BJ, Gil-Henn H, Mader CC, Halo T, Yin T, Condeelis J, Machida K, Wu YI, Koleske AJ: Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells. Mol Biol Cell. 2017 May 15; 2017 Mar 29. PMID: 28356423

Yu P, Wilhelm K, Dubrac A, Tung JK, Alves TC, Fang JS, Xie Y, Zhu J, Chen Z, De Smet F, Zhang J, Jin SW, Sun L, Sun H, Kibbey RG, Hirschi KK, Hay N, Carmeliet P, Chittenden TW, Eichmann A, Potente M, Simons M: FGF-dependent metabolic control of vascular development. Nature. 2017 May 11; 2017 May 3. PMID: 28467822

Stojkovic V, Simpson CA, Sullivan RR, Cusano AM, Kerstetter JE, Kenny AM, Insogna KL, Bihuniak JD: The Effect of Dietary Glycemic Properties on Markers of Inflammation, Insulin Resistance, and Body Composition in Postmenopausal American Women: An Ancillary Study from a Multicenter Protein Supplementation Trial. Nutrients. 2017 May 11; 2017 May 11. PMID: 28492492

Kruglov E, Ananthanarayanan M, Sousa P, Weerachayaphorn J, Guerra MT, Nathanson MH: Type 2 inositol trisphosphate receptor gene expression in hepatocytes is regulated by cyclic AMP. Biochem Biophys Res Commun. 2017 May 6; 2017 Mar 19. PMID: 28327356

Holmes WR, Park J, Levchenko A, Edelstein-Keshet L: A mathematical model coupling polarity signaling to cell adhesion explains diverse cell migration patterns. PLoS Comput Biol. 2017 May; 2017 May 4. PMID: 28472054

Tio CW, Omerza G, Phillips T, Lou HJ, Turk BE, Winter E: Ssp2 Binding Activates the Smk1 Mitogen-Activated Protein Kinase. Mol Cell Biol. 2017 May 15; 2017 May 2. PMID: 28223369

Chakraborty A, Hatzis C, DiGiovanna MP: Co-targeting the HER and IGF/insulin receptor axis in breast cancer, with triple targeting with endocrine therapy for hormone-sensitive disease. Breast Cancer Res Treat. 2017 May; 2017 Feb 24. PMID: 28236033

Wang S, Yang X: Inter-organ regulation of adipose tissue browning. Cell Mol Life Sci. 2017 May; 2016 Nov 19. PMID: 27866221

Caprio S, Perry R, Kursawe R: Adolescent Obesity and Insulin Resistance: Roles of Ectopic Fat Accumulation and Adipose Inflammation. Gastroenterology. 2017 May; 2017 Feb 10. PMID: 28192105

Allam A, Schulz PJ, Krauthammer M: Toward automated assessment of health Web page quality using the DISCERN instrument. J Am Med Inform Assoc. 2017 May 1. PMID: 27707819

Shapiro LP, Parsons RG, Koleske AJ, Gourley SL: Differential expression of cytoskeletal regulatory factors in the adolescent prefrontal cortex: Implications for cortical development. J Neurosci Res. 2017 May; 2016 Oct 13. PMID: 27735056

Lazova R, Pornputtapong N, Halaban R, Bosenberg M, Bai Y, Chai H, Krauthammer M: Spitz nevi and Spitzoid melanomas: exome sequencing and comparison with conventional melanocytic nevi and melanomas. Mod Pathol. 2017 May; 2017 Feb 10. PMID: 28186096

Crawford ED, Shore ND, Petrylak DP, Higano CS, Ryan CJ: Abiraterone acetate and prednisone in chemotherapy-naïve prostate cancer patients: rationale, evidence and clinical utility. Ther Adv Med Oncol. 2017 May; 2017 Mar 22. PMID: 28529549

Crawford ED, Petrylak D, Sartor O: Navigating the evolving therapeutic landscape in advanced prostate cancer. Urol Oncol. 2017 May; 2017 Mar 7. PMID: 28283376

Moore JO, Lemmon MA, Ferguson KM: Dimerization of Tie2 mediated by its membrane-proximal FNIII domains. Proc Natl Acad Sci U S A. 2017 Apr 25; 2017 Apr 10. PMID: 28396397

Jeong J, VanHouten JN, Kim W, Dann P, Sullivan C, Choi J, Sneddon WB, Friedman PA, Wysolmerski JJ: The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2. J Biol Chem. 2017 Apr 21; 2017 Feb 24. PMID: 28235801

Cobbaut M, Derua R, Döppler H, Lou HJ, Vandoninck S, Storz P, Turk BE, Seufferlein T, Waelkens E, Janssens V, Van Lint J: Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop. Sci Rep. 2017 Apr 20; 2017 Apr 20. PMID: 28428613

Stevens LE, Cheung WKC, Adua SJ, Arnal-Estapé A, Zhao M, Liu Z, Brewer K, Herbst RS, Nguyen DX: Extracellular Matrix Receptor Expression in Subtypes of Lung Adenocarcinoma Potentiates Outgrowth of Micrometastases. Cancer Res. 2017 Apr 15; 2017 Feb 14. PMID: 28196904

Mao L, Shen L, Chen J, Zhang X, Kwak M, Wu Y, Fan R, Zhang L, Pei J, Yuan G, Song C, Ge J, Ding W: A promising biodegradable magnesium alloy suitable for clinical vascular stent application. Sci Rep. 2017 Apr 11; 2017 Apr 11. PMID: 28397881

Horsley V, Watt F: Repeal and Replace: Adipocyte Regeneration in Wound Repair. Cell Stem Cell. 2017 Apr 6. PMID: 28388424

Habibi I, Cheong R, Lipniacki T, Levchenko A, Emamian ES, Abdi A: Computation and measurement of cell decision making errors using single cell data. PLoS Comput Biol. 2017 Apr; 2017 Apr 5. PMID: 28379950

Jeong J, Kim W, Kim LK, VanHouten J, Wysolmerski JJ: HER2 signaling regulates HER2 localization and membrane retention. PLoS One. 2017; 2017 Apr 3. PMID: 28369073

Martin NM, Cooke KM, Radford CC, Perley LE, Silasi M, Flannery CA: Time course analysis of RNA quality in placenta preserved by RNAlater or flash freezing. Am J Reprod Immunol. 2017 Apr; 2017 Jan 31. PMID: 28138995

Zhang X, Fernández-Hernando C: MiR-33 regulation of stretch-induced intimal hyperplasia in vein grafts. Cardiovasc Res. 2017 Apr 1. PMID: 28339676

Carvajal-Hausdorf DE, Schalper KA, Bai Y, Black J, Santin AD, Rimm DL: Objective, domain-specific HER2 measurement in uterine and ovarian serous carcinomas and its clinical significance. Gynecol Oncol. 2017 Apr; 2017 Feb 11. PMID: 28196634

Li Y, Lu M, Alvarez-Lugo L, Chen G, Chai TC: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is released by female mouse bladder urothelial cells and expressed by the urothelium as an early response to lipopolysaccharides (LPS). Neurourol Urodyn. 2017 Apr; 2016 Jun 23. PMID: 27337494

Sharabi K, Lin H, Tavares CDJ, Dominy JE, Camporez JP, Perry RJ, Schilling R, Rines AK, Lee J, Hickey M, Bennion M, Palmer M, Nag PP, Bittker JA, Perez J, Jedrychowski MP, Ozcan U, Gygi SP, Kamenecka TM, Shulman GI, Schreiber SL, Griffin PR, Puigserver P: Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes. Cell. 2017 Mar 23. PMID: 28340340

Smithy JW, Moore LM, Pelekanou V, Rehman J, Gaule P, Wong PF, Neumeister VM, Sznol M, Kluger HM, Rimm DL: Nuclear IRF-1 expression as a mechanism to assess "Capability" to express PD-L1 and response to PD-1 therapy in metastatic melanoma. J Immunother Cancer. 2017; 2017 Mar 21. PMID: 28331615

Liu J, Guo B, Chen Z, Wang N, Iacovino M, Cheng J, Roden C, Pan W, Khan S, Chen S, Kyba M, Fan R, Guo S, Lu J: miR-125b promotes MLL-AF9-driven murine acute myeloid leukemia involving a VEGFA-mediated non-cell-intrinsic mechanism. Blood. 2017 Mar 16; 2017 Jan 4. PMID: 28053194

Bellmunt J, de Wit R, Vaughn DJ, Fradet Y, Lee JL, Fong L, Vogelzang NJ, Climent MA, Petrylak DP, Choueiri TK, Necchi A, Gerritsen W, Gurney H, Quinn DI, Culine S, Sternberg CN, Mai Y, Poehlein CH, Perini RF, Bajorin DF, KEYNOTE-045 Investigators.: Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma. N Engl J Med. 2017 Mar 16; 2017 Feb 17. PMID: 28212060

Perry RJ, Peng L, Cline GW, Petersen KF, Shulman GI: A Non-invasive Method to Assess Hepatic Acetyl-CoA In Vivo. Cell Metab. 2017 Mar 7; 2017 Jan 19. PMID: 28111213

Ryu HY, Hochstrasser M: Adaptive aneuploidy counters a dysregulated SUMO system. Cell Cycle. 2017 Mar 4; 2016 Nov 18. PMID: 27860533

Zhang X, Fernández-Hernando C: miR-33 Regulation of Adaptive Fibrotic Response in Cardiac Remodeling. Circ Res. 2017 Mar 3. PMID: 28254794

Lee H, Min K, Yi JS, Shi H, Chang W, Jackson L, Bennett AM: A Phosphoproteomic Screen Identifies a Guanine Nucleotide Exchange Factor for Rab3A Protein as a Mitogen-activated Protein (MAP) Kinase Phosphatase-5-regulated MAP Kinase Target in Interleukin 6 (IL-6) Secretion and Myogenesis. J Biol Chem. 2017 Mar 3; 2017 Jan 17. PMID: 28096466

Akalu YT, Rothlin CV, Ghosh S: TAM receptor tyrosine kinases as emerging targets of innate immune checkpoint blockade for cancer therapy. Immunol Rev. 2017 Mar. PMID: 28258690

Viscoli CM, Inzucchi SE, Young LH, Insogna KL, Conwit R, Furie KL, Gorman M, Kelly MA, Lovejoy AM, Kernan WN, IRIS Trial Investigators.: Pioglitazone and Risk for Bone Fracture: Safety Data From a Randomized Clinical Trial. J Clin Endocrinol Metab. 2017 Mar 1. PMID: 27935736

Han C, Yang Y, Te Morsche RH, Drenth JP, Politei JM, Waxman SG, Dib-Hajj SD: Familial gain-of-function Nav1.9 mutation in a painful channelopathy. J Neurol Neurosurg Psychiatry. 2017 Mar; 2016 Aug 8. PMID: 27503742

Toki MI, Cecchi F, Hembrough T, Syrigos KN, Rimm DL: Proof of the quantitative potential of immunofluorescence by mass spectrometry. Lab Invest. 2017 Mar; 2017 Jan 16. PMID: 28092364

Rehman JA, Han G, Carvajal-Hausdorf DE, Wasserman BE, Pelekanou V, Mani NL, McLaughlin J, Schalper KA, Rimm DL: Quantitative and pathologist-read comparison of the heterogeneity of programmed death-ligand 1 (PD-L1) expression in non-small cell lung cancer. Mod Pathol. 2017 Mar; 2016 Nov 11. PMID: 27834350

Park S, Gonzalez DG, Guirao B, Boucher JD, Cockburn K, Marsh ED, Mesa KR, Brown S, Rompolas P, Haberman AM, Bellaïche Y, Greco V: Tissue-scale coordination of cellular behaviour promotes epidermal wound repair in live mice. Nat Cell Biol. 2017 Mar 1; 2017 Mar 1. PMID: 28248302

Beckmann JF, Ronau JA, Hochstrasser M: A Wolbachia deubiquitylating enzyme induces cytoplasmic incompatibility. Nat Microbiol. 2017 Mar 1; 2017 Mar 1. PMID: 28248294

de Kouchkovsky DA, Ghosh S, Rothlin CV: Negative Regulation of Type 2 Immunity. Trends Immunol. 2017 Mar; 2017 Jan 9. PMID: 28082101

Kapetis D, Sassone J, Yang Y, Galbardi B, Xenakis MN, Westra RL, Szklarczyk R, Lindsey P, Faber CG, Gerrits M, Merkies IS, Dib-Hajj SD, Mantegazza M, Waxman SG, Lauria G, PROPANE Study Group.: Network topology of NaV1.7 mutations in sodium channel-related painful disorders. BMC Syst Biol. 2017 Feb 24; 2017 Feb 24. PMID: 28235406

van den Pol AN, Mao G, Yang Y, Ornaghi S, Davis JN: Zika Virus Targeting in the Developing Brain. J Neurosci. 2017 Feb 22; 2017 Jan 25. PMID: 28123079

Tzouvelekis A, Yu G, Lino Cardenas CL, Herazo-Maya JD, Wang R, Woolard T, Zhang Y, Sakamoto K, Lee H, Yi JS, DeIuliis G, Xylourgidis N, Ahangari F, Lee PJ, Aidinis V, Herzog EL, Homer R, Bennett AM, Kaminski N: SH2 Domain-Containing Phosphatase-2 Is a Novel Antifibrotic Regulator in Pulmonary Fibrosis. Am J Respir Crit Care Med. 2017 Feb 15. PMID: 27736153

Gao B, Huang C, Kernstine K, Pelekanou V, Kluger Y, Jiang T, Peters-Hall JR, Coquelin M, Girard L, Zhang W, Huffman K, Oliver D, Kinose F, Haura E, Teer JK, Rix U, Le AT, Aisner DL, Varella-Garcia M, Doebele RC, Covington KR, Hampton OA, Doddapaneni HV, Jayaseelan JC, Hu J, Wheeler DA, Shay JW, Rimm DL, Gazdar A, Minna JD: Non-malignant respiratory epithelial cells preferentially proliferate from resected non-small cell lung cancer specimens cultured under conditionally reprogrammed conditions. Oncotarget. 2017 Feb 14. PMID: 28052041

Corbit KC, Camporez JPG, Tran JL, Wilson CG, Lowe DA, Nordstrom SM, Ganeshan K, Perry RJ, Shulman GI, Jurczak MJ, Weiss EJ: Adipocyte JAK2 mediates growth hormone-induced hepatic insulin resistance. JCI Insight. 2017 Feb 9; 2017 Feb 9. PMID: 28194444

Draheim KM, Huet-Calderwood C, Simon B, Calderwood DA: Nuclear Localization of Integrin Cytoplasmic Domain-associated Protein-1 (ICAP1) Influences β1 Integrin Activation and Recruits Krev/Interaction Trapped-1 (KRIT1) to the Nucleus. J Biol Chem. 2017 Feb 3; 2016 Dec 21. PMID: 28003363

Willeit P, Skroblin P, Moschen AR, Yin X, Kaudewitz D, Zampetaki A, Barwari T, Whitehead M, Ramírez CM, Goedeke L, Rotllan N, Bonora E, Hughes AD, Santer P, Fernández-Hernando C, Tilg H, Willeit J, Kiechl S, Mayr M: Circulating MicroRNA-122 Is Associated With the Risk of New-Onset Metabolic Syndrome and Type 2 Diabetes. Diabetes. 2017 Feb; 2016 Nov 29. PMID: 27899485

Vogelzang NJ, Fizazi K, Burke JM, De Wit R, Bellmunt J, Hutson TE, Crane E, Berry WR, Doner K, Hainsworth JD, Wiechno PJ, Liu K, Waldman MF, Gandhi A, Barton D, Jungnelius U, Fandi A, Sternberg CN, Petrylak DP: Circulating Tumor Cells in a Phase 3 Study of Docetaxel and Prednisone with or without Lenalidomide in Metastatic Castration-resistant Prostate Cancer. Eur Urol. 2017 Feb; 2016 Aug 10. PMID: 27522164

Feriod CN, Oliveira AG, Guerra MT, Nguyen L, Richards KM, Jurczak MJ, Ruan HB, Camporez JP, Yang X, Shulman GI, Bennett AM, Nathanson MH, Ehrlich BE: Hepatic Inositol 1,4,5 Trisphosphate Receptor Type 1 Mediates Fatty Liver. Hepatol Commun. 2017 Feb; 2016 Nov 11. PMID: 28966992

Sun TY, Haberman AM, Greco V: Preclinical Advances with Multiphoton Microscopy in Live Imaging of Skin Cancers. J Invest Dermatol. 2017 Feb; 2016 Nov 12. PMID: 27847119

Gaule P, Smithy JW, Toki M, Rehman J, Patell-Socha F, Cougot D, Collin P, Morrill P, Neumeister V, Rimm DL: A Quantitative Comparison of Antibodies to Programmed Cell Death 1 Ligand 1. JAMA Oncol. 2017 Feb 1. PMID: 27541827

Ferris HA, Perry RJ, Moreira GV, Shulman GI, Horton JD, Kahn CR: Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism. Proc Natl Acad Sci U S A. 2017 Jan 31; 2017 Jan 17. PMID: 28096339

Goldberg AB, Cho E, Miller CJ, Lou HJ, Turk BE: Identification of a Substrate-selective Exosite within the Metalloproteinase Anthrax Lethal Factor. J Biol Chem. 2017 Jan 20; 2016 Dec 1. PMID: 27909054

Wali VB, Langdon CG, Held MA, Platt JT, Patwardhan GA, Safonov A, Aktas B, Pusztai L, Stern DF, Hatzis C: Systematic Drug Screening Identifies Tractable Targeted Combination Therapies in Triple-Negative Breast Cancer. Cancer Res. 2017 Jan 15; 2016 Nov 21. PMID: 27872098

Schalper KA, Carvajal-Hausdorf D, McLaughlin J, Altan M, Velcheti V, Gaule P, Sanmamed MF, Chen L, Herbst RS, Rimm DL: Differential Expression and Significance of PD-L1, IDO-1, and B7-H4 in Human Lung Cancer. Clin Cancer Res. 2017 Jan 15; 2016 Jul 20. PMID: 27440266

Gayvert KM, Aly O, Platt J, Bosenberg MW, Stern DF, Elemento O: A Computational Approach for Identifying Synergistic Drug Combinations. PLoS Comput Biol. 2017 Jan; 2017 Jan 13. PMID: 28085880

Balar AV, Galsky MD, Rosenberg JE, Powles T, Petrylak DP, Bellmunt J, Loriot Y, Necchi A, Hoffman-Censits J, Perez-Gracia JL, Dawson NA, van der Heijden MS, Dreicer R, Srinivas S, Retz MM, Joseph RW, Drakaki A, Vaishampayan UN, Sridhar SS, Quinn DI, Durán I, Shaffer DR, Eigl BJ, Grivas PD, Yu EY, Li S, Kadel EE 3rd, Boyd Z, Bourgon R, Hegde PS, Mariathasan S, Thåström A, Abidoye OO, Fine GD, Bajorin DF, IMvigor210 Study Group.: Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial. Lancet. 2017 Jan 7; 2016 Dec 8. PMID: 27939400

Kitay AM, Geibel JP: Stomach and Bone. Adv Exp Med Biol. 2017. PMID: 29101653

Chen C, Chen H, Zhou HJ, Ji W, Min W: Mechanistic Role of Thioredoxin 2 in Heart Failure. Adv Exp Med Biol. 2017. PMID: 28551792

Suda K, Rozeboom L, Furugaki K, Yu H, Melnick MAC, Ellison K, Rivard CJ, Politi K, Mitsudomi T, Hirsch FR: Increased EGFR Phosphorylation Correlates with Higher Programmed Death Ligand-1 Expression: Analysis of TKI-Resistant Lung Cancer Cell Lines. Biomed Res Int. 2017; 2017 Oct 8. PMID: 29119113

Kitay AM, Link A, Geibel JP: Activation of Secretagogue Independent Gastric Acid Secretion via Endothelial Nitric Oxide Synthase Stimulation in Rats. Cell Physiol Biochem. 2017; 2017 Dec 6. PMID: 29212068

Aldajani MM, Vanicek CN, Alhazzaa N, Lysyy T, Agarwal R, Geibel JP: Acute Effects of Vitamin C Exposure On Colonic Crypts: Direct Modulation of pH Regulation. Cell Physiol Biochem. 2017; 2017 Nov 13. PMID: 29132138

Fan J, Zhou X, Wang Y, Kuang C, Sun Y, Liu X, Toomre D, Xu Y: Differential requirement for N-ethylmaleimide-sensitive factor in endosomal trafficking of transferrin receptor from anterograde trafficking of vesicular stomatitis virus glycoprotein G. FEBS Lett. 2017 Jan; 2017 Jan 1. PMID: 27995606

Knobf MT, Jeon S, Smith B, Harris L, Thompson S, Stacy MR, Insogna K, Sinusas AJ: The Yale Fitness Intervention Trial in female cancer survivors: Cardiovascular and physiological outcomes. Heart Lung. 2017 Sep - Oct; 2017 Aug 10. PMID: 28803675

de Morrée ES, Vogelzang NJ, Petrylak DP, Budnik N, Wiechno PJ, Sternberg CN, Doner K, Bellmunt J, Burke JM, Ochoa de Olza M, Choudhury A, Gschwend JE, Kopyltsov E, Flechon A, van As N, Houede N, Barton D, Fandi A, Jungnelius U, Li S, Li JS, de Wit R: Association of Survival Benefit With Docetaxel in Prostate Cancer and Total Number of Cycles Administered: A Post Hoc Analysis of the Mainsail Study. JAMA Oncol. 2017 Jan 1. PMID: 27560549

Erdmann RS, Toomre D, Schepartz A: STED Imaging of Golgi Dynamics with Cer-SiR: A Two-Component, Photostable, High-Density Lipid Probe for Live Cells. Methods Mol Biol. 2017. PMID: 28924659

Gupta R, Wajapeyee N: Transcriptional Analysis-Based Integrative Genomics Approach to Identify Tumor-Promoting Metabolic Genes. Methods Mol Biol. 2017. PMID: 27832547

Forloni M, Ho T, Sun L, Wajapeyee N: Large-Scale RNA Interference Screening to Identify Transcriptional Regulators of a Tumor Suppressor Gene. Methods Mol Biol. 2017. PMID: 27832546

Perry RJ: Pleotropic Acute and Chronic Effects of Leptin to Reverse Type 1 Diabetes. Postdoc J. 2017 Jan. PMID: 28239611

Mai MV, Krauthammer M: Controlling testing volume for respiratory viruses using machine learning and text mining. AMIA Annu Symp Proc. 2016; 2017 Feb 10. PMID: 28269950

Boddupalli CS, Bar N, Kadaveru K, Krauthammer M, Pornputtapong N, Mai Z, Ariyan S, Narayan D, Kluger H, Deng Y, Verma R, Das R, Bacchiocchi A, Halaban R, Sznol M, Dhodapkar MV, Dhodapkar KM: Interlesional diversity of T cell receptors in melanoma with immune checkpoints enriched in tissue-resident memory T cells. JCI Insight. 2016 Dec 22; 2016 Dec 22. PMID: 28018970

McNeel DG, Bander NH, Beer TM, Drake CG, Fong L, Harrelson S, Kantoff PW, Madan RA, Oh WK, Peace DJ, Petrylak DP, Porterfield H, Sartor O, Shore ND, Slovin SF, Stein MN, Vieweg J, Gulley JL: The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of prostate carcinoma. J Immunother Cancer. 2016; 2016 Dec 20. PMID: 28031820

Yi JS, Huang Y, Kwaczala AT, Kuo IY, Ehrlich BE, Campbell SG, Giordano FJ, Bennett AM: Low-dose dasatinib rescues cardiac function in Noonan syndrome. JCI Insight. 2016 Dec 8; 2016 Dec 8. PMID: 27942593

Suárez Y, Fernández-Hernando C: Preface to: "microRNAs in lipid/energy metabolism and cardiometabolic disease". Biochim Biophys Acta. 2016 Dec; 2016 Jul 7. PMID: 27396679

Goedeke L, Wagschal A, Fernández-Hernando C, Näär AM: miRNA regulation of LDL-cholesterol metabolism. Biochim Biophys Acta. 2016 Dec; 2016 Mar 9. PMID: 26968099

Price NL, Fernández-Hernando C: miRNA regulation of white and brown adipose tissue differentiation and function. Biochim Biophys Acta. 2016 Dec; 2016 Feb 16. PMID: 26898181

Araldi E, Suárez Y: MicroRNAs as regulators of endothelial cell functions in cardiometabolic diseases. Biochim Biophys Acta. 2016 Dec; 2016 Jan 26. PMID: 26825686

Rivera-Gonzalez GC, Shook BA, Andrae J, Holtrup B, Bollag K, Betsholtz C, Rodeheffer MS, Horsley V: Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis. Cell Stem Cell. 2016 Dec 1; 2016 Oct 13. PMID: 27746098

Santin AD, Bellone S, Buza N, Choi J, Schwartz PE, Schlessinger J, Lifton RP: Regression of Chemotherapy-Resistant Polymerase ε (POLE) Ultra-Mutated and MSH6 Hyper-Mutated Endometrial Tumors with Nivolumab. Clin Cancer Res. 2016 Dec 1; 2016 Aug 2. PMID: 27486176

Park S, Greco V, Cockburn K: Live imaging of stem cells: answering old questions and raising new ones. Curr Opin Cell Biol. 2016 Dec; 2016 Jul 27. PMID: 27474806

Baldán Á, Fernández-Hernando C: Truths and controversies concerning the role of miRNAs in atherosclerosis and lipid metabolism. Curr Opin Lipidol. 2016 Dec. PMID: 27755115

Wang Y, Baeyens N, Corti F, Tanaka K, Fang JS, Zhang J, Jin Y, Coon B, Hirschi KK, Schwartz MA, Simons M: Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development. Development. 2016 Dec 1; 2016 Oct 27. PMID: 27789626

Mannam P, Rauniyar N, Lam TT, Luo R, Lee PJ, Srivastava A: MKK3 influences mitophagy and is involved in cigarette smoke-induced inflammation. Free Radic Biol Med. 2016 Dec; 2016 Oct 4. PMID: 27717867

Fan J, Lin R, Xia S, Chen D, Elf SE, Liu S, Pan Y, Xu H, Qian Z, Wang M, Shan C, Zhou L, Lei QY, Li Y, Mao H, Lee BH, Sudderth J, DeBerardinis RJ, Zhang G, Owonikoko T, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Kang S, Doetsch PW, Lonial S, Boggon TJ, Curran WJ, Chen J: Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth. Mol Cell. 2016 Dec 1; 2016 Nov 17. PMID: 27867011

Kraehling JR, Chidlow JH, Rajagopal C, Sugiyama MG, Fowler JW, Lee MY, Zhang X, Ramírez CM, Park EJ, Tao B, Chen K, Kuruvilla L, Larriveé B, Folta-Stogniew E, Ola R, Rotllan N, Zhou W, Nagle MW, Herz J, Williams KJ, Eichmann A, Lee WL, Fernández-Hernando C, Sessa WC: Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells. Nat Commun. 2016 Nov 21; 2016 Nov 21. PMID: 27869117

Ascierto PA, Agarwala S, Botti G, Cesano A, Ciliberto G, Davies MA, Demaria S, Dummer R, Eggermont AM, Ferrone S, Fu YX, Gajewski TF, Garbe C, Huber V, Khleif S, Krauthammer M, Lo RS, Masucci G, Palmieri G, Postow M, Puzanov I, Silk A, Spranger S, Stroncek DF, Tarhini A, Taube JM, Testori A, Wang E, Wargo JA, Yee C, Zarour H, Zitvogel L, Fox BA, Mozzillo N, Marincola FM, Thurin M: Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015. J Transl Med. 2016 Nov 15; 2016 Nov 15. PMID: 27846884

Chen X, Tzekov R, Su M, Hong H, Min W, Han A, Li W: Auranofin Inhibits Retinal Pigment Epithelium Cell Survival through Reactive Oxygen Species-Dependent Epidermal Growth Factor Receptor/ Mitogen-Activated Protein Kinase Signaling Pathway. PLoS One. 2016; 2016 Nov 15. PMID: 27846303

Hochstrasser M: Gyre and gimble in the proteasome. Proc Natl Acad Sci U S A. 2016 Nov 15; 2016 Nov 3. PMID: 27810957

Willeit P, Skroblin P, Kiechl S, Fernández-Hernando C, Mayr M: Liver microRNAs: potential mediators and biomarkers for metabolic and cardiovascular disease? Eur Heart J. 2016 Nov 14; 2016 Apr 20. PMID: 27099265

Hurwitz ME, Sokhn J, Petrylak DP: Cancer immunotherapy: new applications in urologic oncology. Curr Opin Urol. 2016 Nov. PMID: 27584025

Tagawa ST, Posadas EM, Bruce J, Lim EA, Petrylak DP, Peng W, Kheoh T, Maul S, Smit JW, Gonzalez MD, De Porre P, Tran N, Nanus DM: Phase 1b Study of Abiraterone Acetate Plus Prednisone and Docetaxel in Patients with Metastatic Castration-resistant Prostate Cancer. Eur Urol. 2016 Nov; 2016 Feb 3. PMID: 26852075

Toki MI, Carvajal-Hausdorf DE, Altan M, McLaughlin J, Henick B, Schalper KA, Syrigos KN, Rimm DL: EGFR-GRB2 Protein Colocalization Is a Prognostic Factor Unrelated to Overall EGFR Expression or EGFR Mutation in Lung Adenocarcinoma. J Thorac Oncol. 2016 Nov; 2016 Jul 20. PMID: 27449805

Chai TC: Caloric Restriction and Aging Bladder Dysfunction. J Urol. 2016 Nov; 2016 Aug 9. PMID: 27520084

Losada L, Amundsen CL, Ashton-Miller J, Chai T, Close C, Damaser M, DiSanto M, Dmochowski R, Fraser MO, Kielb SJ, Kuchel G, Mueller ER, Parker-Autry C, Wolfe AJ, Mallampalli MP: Expert Panel Recommendations on Lower Urinary Tract Health of Women Across Their Life Span. J Womens Health (Larchmt). 2016 Nov; 2016 Jun 10. PMID: 27285829

Sharma P, Callahan MK, Bono P, Kim J, Spiliopoulou P, Calvo E, Pillai RN, Ott PA, de Braud F, Morse M, Le DT, Jaeger D, Chan E, Harbison C, Lin CS, Tschaika M, Azrilevich A, Rosenberg JE: Nivolumab monotherapy in recurrent metastatic urothelial carcinoma (CheckMate 032): a multicentre, open-label, two-stage, multi-arm, phase 1/2 trial. Lancet Oncol. 2016 Nov; 2016 Oct 9. PMID: 27733243

Greco V: The thrill of scientific discovery and leadership with my group. Mol Biol Cell. 2016 Nov 1. PMID: 27799490

Ferstl FS, Kitay AM, Trattnig RM, Alsaihati A, Geibel JP: Secretagogue-dependent and -independent transport of zinc hydration forms in rat parietal cells. Pflugers Arch. 2016 Nov; 2016 Oct 19. PMID: 27757581

Zhao S, Bellone S, Lopez S, Thakral D, Schwab C, English DP, Black J, Cocco E, Choi J, Zammataro L, Predolini F, Bonazzoli E, Bi M, Buza N, Hui P, Wong S, Abu-Khalaf M, Ravaggi A, Bignotti E, Bandiera E, Romani C, Todeschini P, Tassi R, Zanotti L, Odicino F, Pecorelli S, Donzelli C, Ardighieri L, Facchetti F, Falchetti M, Silasi DA, Ratner E, Azodi M, Schwartz PE, Mane S, Angioli R, Terranova C, Quick CM, Edraki B, Bilgüvar K, Lee M, Choi M, Stiegler AL, Boggon TJ, Schlessinger J, Lifton RP, Santin AD: Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial-mesenchymal transition. Proc Natl Acad Sci U S A. 2016 Oct 25; 2016 Oct 10. PMID: 27791010

Montenont E, Echagarruga C, Allen N, Araldi E, Suarez Y, Berger JS: Platelet WDR1 suppresses platelet activity and is associated with cardiovascular disease. Blood. 2016 Oct 20; 2016 Sep 8. PMID: 27609643

Kilic O, Pamies D, Lavell E, Schiapparelli P, Feng Y, Hartung T, Bal-Price A, Hogberg HT, Quinones-Hinojosa A, Guerrero-Cazares H, Levchenko A: Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis. Lab Chip. 2016 Oct 18. PMID: 27722368

McFadden DG, Politi K, Bhutkar A, Chen FK, Song X, Pirun M, Santiago PM, Kim-Kiselak C, Platt JT, Lee E, Hodges E, Rosebrock AP, Bronson RT, Socci ND, Hannon GJ, Jacks T, Varmus H: Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma. Proc Natl Acad Sci U S A. 2016 Oct 18; 2016 Oct 4. PMID: 27702896

Khamphaya T, Chansela P, Piyachaturawat P, Suksamrarn A, Nathanson MH, Weerachayaphorn J: Effects of andrographolide on intrahepatic cholestasis induced by alpha-naphthylisothiocyanate in rats. Eur J Pharmacol. 2016 Oct 15; 2016 Jul 27. PMID: 27475677

Shook B, Rivera Gonzalez G, Ebmeier S, Grisotti G, Zwick R, Horsley V: The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches. Annu Rev Cell Dev Biol. 2016 Oct 6; 2016 May 4. PMID: 27146311

Conlon P, Gelin-Licht R, Ganesan A, Zhang J, Levchenko A: Single-cell dynamics and variability of MAPK activity in a yeast differentiation pathway. Proc Natl Acad Sci U S A. 2016 Oct 4; 2016 Sep 20. PMID: 27651485

Chai TC, Russo A, Yu S, Lu M: Mucosal signaling in the bladder. Auton Neurosci. 2016 Oct; 2015 Sep 24. PMID: 26422993

Jafri MA, Cohen JV, Much MA, Petrylak DP, Podoltsev NA: A Patient With Pancytopenia, Intractable Epistaxis, and Metastatic Prostate Cancer: How Correct Diagnosis of Primary Hyperfibrinolysis Helps to Stop the Bleeding. Clin Genitourin Cancer. 2016 Oct; 2016 May 27. PMID: 27320762

Flannery CA, Fleming AG, Choe GH, Naqvi H, Zhang M, Sharma A, Taylor HS: Endometrial Cancer-Associated FGF18 Expression Is Reduced by Bazedoxifene in Human Endometrial Stromal Cells In Vitro and in Murine Endometrium. Endocrinology. 2016 Oct; 2016 Jun 6. PMID: 27267714

Pesta DH, Tsirigotis DN, Befroy DE, Caballero D, Jurczak MJ, Rahimi Y, Cline GW, Dufour S, Birkenfeld AL, Rothman DL, Carpenter TO, Insogna K, Petersen KF, Bergwitz C, Shulman GI: Hypophosphatemia promotes lower rates of muscle ATP synthesis. FASEB J. 2016 Oct; 2016 Jun 23. PMID: 27338702

Zhao L, Feng Z, Yang X, Liu J: The regulatory roles of O-GlcNAcylation in mitochondrial homeostasis and metabolic syndrome. Free Radic Res. 2016 Oct; 2016 Oct 19. PMID: 27646831

Clark PE, Spiess PE, Agarwal N, Bangs R, Boorjian SA, Buyyounouski MK, Efstathiou JA, Flaig TW, Friedlander T, Greenberg RE, Guru KA, Hahn N, Herr HW, Hoimes C, Inman BA, Kader AK, Kibel AS, Kuzel TM, Lele SM, Meeks JJ, Michalski J, Montgomery JS, Pagliaro LC, Pal SK, Patterson A, Petrylak D, Plimack ER, Pohar KS, Porter MP, Sexton WJ, Siefker-Radtke AO, Sonpavde G, Tward J, Wile G, Dwyer MA, Smith C: NCCN Guidelines Insights: Bladder Cancer, Version 2.2016. J Natl Compr Canc Netw. 2016 Oct. PMID: 27697976

Denkert C, Wienert S, Poterie A, Loibl S, Budczies J, Badve S, Bago-Horvath Z, Bane A, Bedri S, Brock J, Chmielik E, Christgen M, Colpaert C, Demaria S, Van den Eynden G, Floris G, Fox SB, Gao D, Ingold Heppner B, Kim SR, Kos Z, Kreipe HH, Lakhani SR, Penault-Llorca F, Pruneri G, Radosevic-Robin N, Rimm DL, Schnitt SJ, Sinn BV, Sinn P, Sirtaine N, O'Toole SA, Viale G, Van de Vijver K, de Wind R, von Minckwitz G, Klauschen F, Untch M, Fasching PA, Reimer T, Willard-Gallo K, Michiels S, Loi S, Salgado R: Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group. Mod Pathol. 2016 Oct; 2016 Jul 1. PMID: 27363491

Yun S, Budatha M, Dahlman JE, Coon BG, Cameron RT, Langer R, Anderson DG, Baillie G, Schwartz MA: Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling. Nat Cell Biol. 2016 Oct; 2016 Sep 5. PMID: 27595237

Uhlen M, Bandrowski A, Carr S, Edwards A, Ellenberg J, Lundberg E, Rimm DL, Rodriguez H, Hiltke T, Snyder M, Yamamoto T: A proposal for validation of antibodies. Nat Methods. 2016 Oct; 2016 Sep 5. PMID: 27595404

Kim W, Wysolmerski JJ: Calcium-Sensing Receptor in Breast Physiology and Cancer. Front Physiol. 2016; 2016 Sep 30. PMID: 27746743

Black-Schaffer WS, Morrow JS, Prystowsky MB, Steinberg JJ: Training Pathology Residents to Practice 21st Century Medicine: A Proposal. Acad Pathol. 2016 Jan-Dec; 2016 Sep 28. PMID: 28725776

Baeyens N, Larrivée B, Ola R, Hayward-Piatkowskyi B, Dubrac A, Huang B, Ross TD, Coon BG, Min E, Tsarfati M, Tong H, Eichmann A, Schwartz MA: Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia. J Cell Biol. 2016 Sep 26; 2016 Sep 19. PMID: 27646277

Jiang M, Qiu Z, Zhang S, Fan X, Cai X, Xu B, Li X, Zhou J, Zhang X, Chu Y, Wang W, Liang J, Horvath T, Yang X, Wu K, Nie Y, Fan D: Elevated O-GlcNAcylation promotes gastric cancer cells proliferation by modulating cell cycle related proteins and ERK 1/2 signaling. Oncotarget. 2016 Sep 20. PMID: 27542217

Kim W, Takyar FM, Swan K, Jeong J, VanHouten J, Sullivan C, Dann P, Yu H, Fiaschi-Taesch N, Chang W, Wysolmerski J: Calcium-Sensing Receptor Promotes Breast Cancer by Stimulating Intracrine Actions of Parathyroid Hormone-Related Protein. Cancer Res. 2016 Sep 15; 2016 Jul 22. PMID: 27450451

Gettinger S, Politi K: PD-1 Axis Inhibitors in EGFR- and ALK-Driven Lung Cancer: Lost Cause? Clin Cancer Res. 2016 Sep 15; 2016 Jul 28. PMID: 27470969

Ahmed M, Sottnik JL, Dancik GM, Sahu D, Hansel DE, Theodorescu D, Schwartz MA: An Osteopontin/CD44 Axis in RhoGDI2-Mediated Metastasis Suppression. Cancer Cell. 2016 Sep 12; 2016 Sep 1. PMID: 27593345

Gupta R, Forloni M, Bisserier M, Dogra SK, Yang Q, Wajapeyee N: Interferon alpha-inducible protein 6 regulates NRASQ61K-induced melanomagenesis and growth. Elife. 2016 Sep 8; 2016 Sep 8. PMID: 27608486

Balestrini JL, Gard AL, Gerhold KA, Wilcox EC, Liu A, Schwan J, Le AV, Baevova P, Dimitrievska S, Zhao L, Sundaram S, Sun H, Rittié L, Dyal R, Broekelmann TJ, Mecham RP, Schwartz MA, Niklason LE, White ES: Comparative biology of decellularized lung matrix: Implications of species mismatch in regenerative medicine. Biomaterials. 2016 Sep; 2016 Jun 16. PMID: 27344365

Petrylak DP: From the Guest Editor: The Spectrum of Treatment of Metastatic Prostate Cancer: Present and Future. Cancer J. 2016 Sep/Oct. PMID: 27749323

Pawar A, Meier JA, Dasgupta A, Diwanji N, Deshpande N, Saxena K, Buwa N, Inchanalkar S, Schwartz MA, Balasubramanian N: Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling. Cell Signal. 2016 Sep; 2016 Jun 4. PMID: 27269287

Chung C, Insogna KL: The liver throws the skeleton a bone (resorption factor). Hepatology. 2016 Sep; 2016 Jul 25. PMID: 27312397

Shook B, Xiao E, Kumamoto Y, Iwasaki A, Horsley V: CD301b+ Macrophages Are Essential for Effective Skin Wound Healing. J Invest Dermatol. 2016 Sep; 2016 Jun 7. PMID: 27287183

Halaban R, Krauthammer M: RASopathy Gene Mutations in Melanoma. J Invest Dermatol. 2016 Sep; 2016 May 25. PMID: 27236105

Chai TC, Moalli PA, Richter HE, Lake AG, Kim HY, Nager CW, Sirls LT, Brubaker L, Kusek JW: Preoperative Urodynamic Parameters (Valsalva Leak Point Pressure and Maximum Urethral Closure Pressure), Urinary Collagen and Plasma Vitamin D Levels as Predictors of Mid Urethral Sling Surgery Outcome. J Urol. 2016 Sep; 2016 Apr 23. PMID: 27113967

Zarrella ER, Coulter M, Welsh AW, Carvajal DE, Schalper KA, Harigopal M, Rimm DL, Neumeister VM: Automated measurement of estrogen receptor in breast cancer: a comparison of fluorescent and chromogenic methods of measurement. Lab Invest. 2016 Sep; 2016 Jun 27. PMID: 27348626

Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, Liang X, Wang Z, Yuan Q, Vortmeyer A, Toomre D, Fuh G, Yan M, Kluger MS, Wu D, Min W: Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016 Sep; 2016 Aug 22. PMID: 27548575

Gerhold KA, Schwartz MA: Ion Channels in Endothelial Responses to Fluid Shear Stress. Physiology (Bethesda). 2016 Sep. PMID: 27511462

Nagarajan A, Petersen MC, Nasiri AR, Butrico G, Fung A, Ruan HB, Kursawe R, Caprio S, Thibodeau J, Bourgeois-Daigneault MC, Sun L, Gao G, Bhanot S, Jurczak MJ, Green MR, Shulman GI, Wajapeyee N: MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels. Nat Commun. 2016 Aug 31; 2016 Aug 31. PMID: 27577745

Zou S, Teixeira AM, Yin M, Xiang Y, Xavier-Ferrucio J, Zhang PX, Hwa J, Min W, Krause DS: Leukaemia-associated Rho guanine nucleotide exchange factor (LARG) plays an agonist specific role in platelet function through RhoA activation. Thromb Haemost. 2016 Aug 30; 2016 Jun 23. PMID: 27345948

McClure-Begley TD, Esterlis I, Stone KL, Lam TT, Grady SR, Colangelo CM, Lindstrom JM, Marks MJ, Picciotto MR: Evaluation of the Nicotinic Acetylcholine Receptor-Associated Proteome at Baseline and Following Nicotine Exposure in Human and Mouse Cortex. eNeuro. 2016 Jul-Aug; 2016 Aug 16. PMID: 27559543

Shi X, Sousa LP, Mandel-Bausch EM, Tome F, Reshetnyak AV, Hadari Y, Schlessinger J, Lax I: Distinct cellular properties of oncogenic KIT receptor tyrosine kinase mutants enable alternative courses of cancer cell inhibition. Proc Natl Acad Sci U S A. 2016 Aug 16; 2016 Aug 1. PMID: 27482095

Ryu HY, Wilson NR, Mehta S, Hwang SS, Hochstrasser M: Loss of the SUMO protease Ulp2 triggers a specific multichromosome aneuploidy. Genes Dev. 2016 Aug 15; 2016 Sep 1. PMID: 27585592

Wetzel DM, Rhodes EL, Li S, McMahon-Pratt D, Koleske AJ: The Src kinases Hck, Fgr and Lyn activate Arg to facilitate IgG-mediated phagocytosis and Leishmania infection. J Cell Sci. 2016 Aug 15; 2016 Jun 29. PMID: 27358479

Huang F, Sirinakis G, Allgeyer ES, Schroeder LK, Duim WC, Kromann EB, Phan T, Rivera-Molina FE, Myers JR, Irnov I, Lessard M, Zhang Y, Handel MA, Jacobs-Wagner C, Lusk CP, Rothman JE, Toomre D, Booth MJ, Bewersdorf J: Ultra-High Resolution 3D Imaging of Whole Cells. Cell. 2016 Aug 11; 2016 Jul 7. PMID: 27397506

Kukic I, Rivera-Molina F, Toomre D: The IN/OUT assay: a new tool to study ciliogenesis. Cilia. 2016; 2016 Aug 4. PMID: 27493724

Shi X, Mihaylova VT, Kuruvilla L, Chen F, Viviano S, Baldassarre M, Sperandio D, Martinez R, Yue P, Bates JG, Breckenridge DG, Schlessinger J, Turk BE, Calderwood DA: Loss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-β-dependent mechanisms. Proc Natl Acad Sci U S A. 2016 Aug 2; 2016 Jul 18. PMID: 27432991

Du W, Wong C, Song Y, Shen H, Mori D, Rotllan N, Price N, Dobrian AD, Meng H, Kleinstein SH, Fernandez-Hernando C, Goldstein DR: Age-associated vascular inflammation promotes monocytosis during atherogenesis. Aging Cell. 2016 Aug; 2016 May 2. PMID: 27135421

Perry RJ, Cardone RL, Petersen MC, Zhang D, Fouqueray P, Hallakou-Bozec S, Bolze S, Shulman GI, Petersen KF, Kibbey RG: Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents. Am J Physiol Endocrinol Metab. 2016 Aug 1; 2016 Jul 12. PMID: 27406738

Wengerter BC, Emre G, Park JY, Geibel J: Three-dimensional Printing in the Intestine. Clin Gastroenterol Hepatol. 2016 Aug; 2016 May 14. PMID: 27189913

Belinsky GS, Sreekumar B, Andrejecsk JW, Saltzman WM, Gong J, Herzog RI, Lin S, Horsley V, Carpenter TO, Chung C: Pigment epithelium-derived factor restoration increases bone mass and improves bone plasticity in a model of osteogenesis imperfecta type VI via Wnt3a blockade. FASEB J. 2016 Aug; 2016 Apr 28. PMID: 27127101

Nathanson MH, Terrault N: Hepatitis B surface antigen loss: Not all that we hoped it would be. Hepatology. 2016 Aug; 2016 Jun 16. PMID: 27178231

Hu SL, Chang A, Perazella MA, Okusa MD, Jaimes EA, Weiss RH, American Society of Nephrology Onco-Nephrology Forum.: The Nephrologist's Tumor: Basic Biology and Management of Renal Cell Carcinoma. J Am Soc Nephrol. 2016 Aug; 2016 Mar 9. PMID: 26961346

Rauch L, Hennings K, Trasak C, Röder A, Schröder B, Koch-Nolte F, Rivera-Molina F, Toomre D, Aepfelbacher M: Staphylococcus aureus recruits Cdc42GAP through recycling endosomes and the exocyst to invade human endothelial cells. J Cell Sci. 2016 Aug 1; 2016 Jun 16. PMID: 27311480

Hsieh E, Fraenkel L, Han Y, Xia W, Insogna KL, Yin MT, Zhu T, Cheng X, Li T: Longitudinal increase in vitamin D binding protein levels after initiation of tenofovir/lamivudine/efavirenz among individuals with HIV. AIDS. 2016 Jul 31. PMID: 27124896

Mani NL, Schalper KA, Hatzis C, Saglam O, Tavassoli F, Butler M, Chagpar AB, Pusztai L, Rimm DL: Quantitative assessment of the spatial heterogeneity of tumor-infiltrating lymphocytes in breast cancer. Breast Cancer Res. 2016 Jul 29; 2016 Jul 29. PMID: 27473061

Aryal B, Rotllan N, Araldi E, Ramírez CM, He S, Chousterman BG, Fenn AM, Wanschel A, Madrigal-Matute J, Warrier N, Martín-Ventura JL, Swirski FK, Suárez Y, Fernández-Hernando C: ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression. Nat Commun. 2016 Jul 27; 2016 Jul 27. PMID: 27460411

Cocco E, Lopez S, Black J, Bellone S, Bonazzoli E, Predolini F, Ferrari F, Schwab CL, Menderes G, Zammataro L, Buza N, Hui P, Wong S, Zhao S, Bai Y, Rimm DL, Ratner E, Litkouhi B, Silasi DA, Azodi M, Schwartz PE, Santin AD: Dual CCNE1/PIK3CA targeting is synergistic in CCNE1-amplified/PIK3CA-mutated uterine serous carcinomas in vitro and in vivo. Br J Cancer. 2016 Jul 26; 2016 Jun 28. PMID: 27351214

Foxman EF, Storer JA, Vanaja K, Levchenko A, Iwasaki A: Two interferon-independent double-stranded RNA-induced host defense strategies suppress the common cold virus at warm temperature. Proc Natl Acad Sci U S A. 2016 Jul 26; 2016 Jul 11. PMID: 27402752

Rich MT, Abbott TB, Chung L, Gulcicek EE, Stone KL, Colangelo CM, Lam TT, Nairn AC, Taylor JR, Torregrossa MM: Phosphoproteomic Analysis Reveals a Novel Mechanism of CaMKIIα Regulation Inversely Induced by Cocaine Memory Extinction versus Reconsolidation. J Neurosci. 2016 Jul 20. PMID: 27445140

Yang Y, Huang J, Mis MA, Estacion M, Macala L, Shah P, Schulman BR, Horton DB, Dib-Hajj SD, Waxman SG: Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli. J Neurosci. 2016 Jul 13. PMID: 27413160

Forloni M, Gupta R, Nagarajan A, Sun LS, Dong Y, Pirazzoli V, Toki M, Wurtz A, Melnick MA, Kobayashi S, Homer RJ, Rimm DL, Gettinger SJ, Politi K, Dogra SK, Wajapeyee N: Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells. Cell Rep. 2016 Jul 12; 2016 Jun 23. PMID: 27346347

Robles-Espinoza CD, Roberts ND, Chen S, Leacy FP, Alexandrov LB, Pornputtapong N, Halaban R, Krauthammer M, Cui R, Timothy Bishop D, Adams DJ: Germline MC1R status influences somatic mutation burden in melanoma. Nat Commun. 2016 Jul 12; 2016 Jul 12. PMID: 27403562

Berk JM, Hochstrasser M: Protein Modification: Bacterial Effectors Rewrite the Rules of Ubiquitylation. Curr Biol. 2016 Jul 11. PMID: 27404243

Freedman LP, Gibson MC, Bradbury AR, Buchberg AM, Davis D, Dolled-Filhart MP, Lund-Johansen F, Rimm DL: [Letter to the Editor] The need for improved education and training in research antibody usage and validation practices. Biotechniques. 2016; 2016 Jul 1. PMID: 27401669

Hollander L, Guo X, Velazquez H, Chang J, Safirstein R, Kluger H, Cha C, Desir GV: Renalase Expression by Melanoma and Tumor-Associated Macrophages Promotes Tumor Growth through a STAT3-Mediated Mechanism. Cancer Res. 2016 Jul 1; 2016 May 9. PMID: 27197188

Giordano FJ, Wang Y, Desir GV: A Remote Role for Renalase. EBioMedicine. 2016 Jul; 2016 Jun 25. PMID: 27374133

Flannery CA, Saleh FL, Choe GH, Selen DJ, Kodaman PH, Kliman HJ, Wood TL, Taylor HS: Differential Expression of IR-A, IR-B and IGF-1R in Endometrial Physiology and Distinct Signature in Adenocarcinoma. J Clin Endocrinol Metab. 2016 Jul; 2016 Apr 18. PMID: 27088794

Yu H, Boyle TA, Zhou C, Rimm DL, Hirsch FR: PD-L1 Expression in Lung Cancer. J Thorac Oncol. 2016 Jul; 2016 Apr 23. PMID: 27117833

Park J, Kim DH, Kim HN, Wang CJ, Kwak MK, Hur E, Suh KY, An SS, Levchenko A: Directed migration of cancer cells guided by the graded texture of the underlying matrix. Nat Mater. 2016 Jul; 2016 Mar 14. PMID: 26974411

Merlino G, Herlyn M, Fisher DE, Bastian BC, Flaherty KT, Davies MA, Wargo JA, Curiel-Lewandrowski C, Weber MJ, Leachman SA, Soengas MS, McMahon M, Harbour JW, Swetter SM, Aplin AE, Atkins MB, Bosenberg MW, Dummer R, Gershenwald JE, Halpern AC, Herlyn D, Karakousis GC, Kirkwood JM, Krauthammer M, Lo RS, Long GV, McArthur G, Ribas A, Schuchter L, Sosman JA, Smalley KS, Steeg P, Thomas NE, Tsao H, Tueting T, Weeraratna A, Xu G, Lomax R, Martin A, Silverstein S, Turnham T, Ronai ZA: The state of melanoma: challenges and opportunities. Pigment Cell Melanoma Res. 2016 Jul; 2016 Apr 17. PMID: 27087480

Nagarajan A, Malvi P, Wajapeyee N: Oncogene-directed alterations in cancer cell metabolism. Trends Cancer. 2016 Jul; 2016 Jun 27. PMID: 27822561

Xiao X, Levy AD, Rosenberg BJ, Higley MJ, Koleske AJ: Disruption of Coordinated Presynaptic and Postsynaptic Maturation Underlies the Defects in Hippocampal Synapse Stability and Plasticity in Abl2/Arg-Deficient Mice. J Neurosci. 2016 Jun 22. PMID: 27335408

Smith CL, Kilic O, Schiapparelli P, Guerrero-Cazares H, Kim DH, Sedora-Roman NI, Gupta S, O'Donnell T, Chaichana KL, Rodriguez FJ, Abbadi S, Park J, Quiñones-Hinojosa A, Levchenko A: Migration Phenotype of Brain-Cancer Cells Predicts Patient Outcomes. Cell Rep. 2016 Jun 21; 2016 Jun 9. PMID: 27292647

Mathea S, Abdul Azeez KR, Salah E, Tallant C, Wolfreys F, Konietzny R, Fischer R, Lou HJ, Brennan PE, Schnapp G, Pautsch A, Kessler BM, Turk BE, Knapp S: Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib. ACS Chem Biol. 2016 Jun 17; 2016 Mar 31. PMID: 26999302

Rompolas P, Mesa KR, Kawaguchi K, Park S, Gonzalez D, Brown S, Boucher J, Klein AM, Greco V: Spatiotemporal coordination of stem cell commitment during epidermal homeostasis. Science. 2016 Jun 17; 2016 May 26. PMID: 27229141

Madiraju AK, Alves T, Zhao X, Cline GW, Zhang D, Bhanot S, Samuel VT, Kibbey RG, Shulman GI: Argininosuccinate synthetase regulates hepatic AMPK linking protein catabolism and ureagenesis to hepatic lipid metabolism. Proc Natl Acad Sci U S A. 2016 Jun 14; 2016 May 31. PMID: 27247419

Deng Y, Rivera-Molina FE, Toomre DK, Burd CG: Sphingomyelin is sorted at the trans Golgi network into a distinct class of secretory vesicle. Proc Natl Acad Sci U S A. 2016 Jun 14; 2016 May 31. PMID: 27247384

Perry RJ, Peng L, Barry NA, Cline GW, Zhang D, Cardone RL, Petersen KF, Kibbey RG, Goodman AL, Shulman GI: Acetate mediates a microbiome-brain-β-cell axis to promote metabolic syndrome. Nature. 2016 Jun 9. PMID: 27279214

Zattas D, Berk JM, Kreft SG, Hochstrasser M: A Conserved C-terminal Element in the Yeast Doa10 and Human MARCH6 Ubiquitin Ligases Required for Selective Substrate Degradation. J Biol Chem. 2016 Jun 3; 2016 Apr 11. PMID: 27068744

Perry RJ, Borders CB, Cline GW, Zhang XM, Alves TC, Petersen KF, Rothman DL, Kibbey RG, Shulman GI: Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism. J Biol Chem. 2016 Jun 3; 2016 Mar 21. PMID: 27002151

Canfrán-Duque A, Lin CS, Goedeke L, Suárez Y, Fernández-Hernando C: Micro-RNAs and High-Density Lipoprotein Metabolism. Arterioscler Thromb Vasc Biol. 2016 Jun; 2016 Apr 14. PMID: 27079881

Ulrich V, Rotllan N, Araldi E, Luciano A, Skroblin P, Abonnenc M, Perrotta P, Yin X, Bauer A, Leslie KL, Zhang P, Aryal B, Montgomery RL, Thum T, Martin K, Suarez Y, Mayr M, Fernandez-Hernando C, Sessa WC: Chronic miR-29 antagonism promotes favorable plaque remodeling in atherosclerotic mice. EMBO Mol Med. 2016 Jun; 2016 Jun 1. PMID: 27137489

Sonpavde G, Pond GR, Templeton AJ, Fandi A, Tombal B, Rosenthal M, Armstrong AJ, Petrylak DP: Association Between RECIST Changes and Survival in Patients with Metastatic Castration-resistant Prostate Cancer Receiving Docetaxel. Eur Urol. 2016 Jun; 2015 Oct 21. PMID: 26497922

Jiang Y, Shi X, Zhao Q, Krauthammer M, Rothberg BE, Ma S: Integrated analysis of multidimensional omics data on cutaneous melanoma prognosis. Genomics. 2016 Jun; 2016 Apr 30. PMID: 27141884

Omary MB, Cohen DE, El-Omar E, Jalan R, Low M, Nathanson M, Peek R, Turner J: Not All Mice Are the Same: Standardization of Animal Research Data Presentation. Gut. 2016 Jun. PMID: 27197119

Vilarinho S, Sari S, Yilmaz G, Stiegler AL, Boggon TJ, Jain D, Akyol G, Dalgic B, Günel M, Lifton RP: Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension. Hepatology. 2016 Jun; 2016 Mar 31. PMID: 26874653

Geha P, Yang Y, Estacion M, Schulman BR, Tokuno H, Apkarian AV, Dib-Hajj SD, Waxman SG: Pharmacotherapy for Pain in a Family With Inherited Erythromelalgia Guided by Genomic Analysis and Functional Profiling. JAMA Neurol. 2016 Jun 1. PMID: 27088781

Zhang YW, Turk BE, Rudnick G: Control of serotonin transporter phosphorylation by conformational state. Proc Natl Acad Sci U S A. 2016 May 17; 2016 May 2. PMID: 27140629

Yushak ML, Han G, Bouberhan S, Epstein L, DiGiovanna MP, Mougalian SS, Sanft TB, Abu-Khalaf MM, Chung GG, Stein SM, Goldberg SB, Pusztai L, Hofstatter EW: Patient preferences regarding incidental genomic findings discovered during tumor profiling. Cancer. 2016 May 15; 2016 Mar 11. PMID: 26970385

Xu Y, Nan D, Fan J, Bogan JS, Toomre D: Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action. J Cell Sci. 2016 May 15; 2016 Apr 13. PMID: 27076519

Ruppe MD, Zhang X, Imel EA, Weber TJ, Klausner MA, Ito T, Vergeire M, Humphrey JS, Glorieux FH, Portale AA, Insogna K, Peacock M, Carpenter TO: Effect of four monthly doses of a human monoclonal anti-FGF23 antibody (KRN23) on quality of life in X-linked hypophosphatemia. Bone Rep. 2016 Dec; 2016 May 13. PMID: 28326356

Halabi S, Kelly WK, Ma H, Zhou H, Solomon NC, Fizazi K, Tangen CM, Rosenthal M, Petrylak DP, Hussain M, Vogelzang NJ, Thompson IM, Chi KN, de Bono J, Armstrong AJ, Eisenberger MA, Fandi A, Li S, Araujo JC, Logothetis CJ, Quinn DI, Morris MJ, Higano CS, Tannock IF, Small EJ: Meta-Analysis Evaluating the Impact of Site of Metastasis on Overall Survival in Men With Castration-Resistant Prostate Cancer. J Clin Oncol. 2016 May 10; 2016 Mar 7. PMID: 26951312

Kumar A, Ouyang M, Van den Dries K, McGhee EJ, Tanaka K, Anderson MD, Groisman A, Goult BT, Anderson KI, Schwartz MA: Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity. J Cell Biol. 2016 May 9. PMID: 27161398

Rosenberg JE, Hoffman-Censits J, Powles T, van der Heijden MS, Balar AV, Necchi A, Dawson N, O'Donnell PH, Balmanoukian A, Loriot Y, Srinivas S, Retz MM, Grivas P, Joseph RW, Galsky MD, Fleming MT, Petrylak DP, Perez-Gracia JL, Burris HA, Castellano D, Canil C, Bellmunt J, Bajorin D, Nickles D, Bourgon R, Frampton GM, Cui N, Mariathasan S, Abidoye O, Fine GD, Dreicer R: Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial. Lancet. 2016 May 7; 2016 Mar 4. PMID: 26952546

Hamill S, Lou HJ, Turk BE, Boggon TJ: Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases. Mol Cell. 2016 May 5. PMID: 27153537

Sun H, Zhu Y, Pan H, Chen X, Balestrini JL, Lam TT, Kanyo JE, Eichmann A, Gulati M, Fares WH, Bai H, Feghali-Bostwick CA, Gan Y, Peng X, Moore MW, White ES, Sava P, Gonzalez AL, Cheng Y, Niklason LE, Herzog EL: Netrin-1 Regulates Fibrocyte Accumulation in the Decellularized Fibrotic Sclerodermatous Lung Microenvironment and in Bleomycin-Induced Pulmonary Fibrosis. Arthritis Rheumatol. 2016 May. PMID: 26749424

Perry RJ, Petersen KF, Shulman GI: Pleotropic effects of leptin to reverse insulin resistance and diabetic ketoacidosis. Diabetologia. 2016 May; 2016 Mar 10. PMID: 26961503

Ching T, Peplowska K, Huang S, Zhu X, Shen Y, Molnar J, Yu H, Tiirikainen M, Fogelgren B, Fan R, Garmire LX: Pan-Cancer Analyses Reveal Long Intergenic Non-Coding RNAs Relevant to Tumor Diagnosis, Subtyping and Prognosis. EBioMedicine. 2016 May; 2016 Mar 19. PMID: 27322459

Pauta M, Rotllan N, Fernández-Hernando A, Langhi C, Ribera J, Lu M, Boix L, Bruix J, Jimenez W, Suárez Y, Ford DA, Baldán A, Birnbaum MJ, Morales-Ruiz M, Fernández-Hernando C: Akt-mediated foxo1 inhibition is required for liver regeneration. Hepatology. 2016 May; 2015 Dec 18. PMID: 26473496

Petrylak DP, Tagawa ST, Kohli M, Eisen A, Canil C, Sridhar SS, Spira A, Yu EY, Burke JM, Shaffer D, Pan CX, Kim JJ, Aragon-Ching JB, Quinn DI, Vogelzang NJ, Tang S, Zhang H, Cavanaugh CT, Gao L, Kauh JS, Walgren RA, Chi KN: Docetaxel As Monotherapy or Combined With Ramucirumab or Icrucumab in Second-Line Treatment for Locally Advanced or Metastatic Urothelial Carcinoma: An Open-Label, Three-Arm, Randomized Controlled Phase II Trial. J Clin Oncol. 2016 May 1; 2016 Feb 29. PMID: 26926681

Horsley V, Kulesz-Martin M, Wang XJ: Montagna Symposium 2015: Harnessing Stem Cells to Reveal Novel Skin Biology and Disease Treatments. J Invest Dermatol. 2016 May. PMID: 27107373

Yang Y, Wang J, Shigematsu H, Xu W, Shih WM, Rothman JE, Lin C: Self-assembly of size-controlled liposomes on DNA nanotemplates. Nat Chem. 2016 May; 2016 Mar 21. PMID: 27102682

Vishwanatha KS, Bäck N, Lam TT, Mains RE, Eipper BA: O-Glycosylation of a Secretory Granule Membrane Enzyme Is Essential for Its Endocytic Trafficking. J Biol Chem. 2016 Apr 29; 2016 Mar 9. PMID: 26961877

Xie Z, Zhang D, Chung D, Tang Z, Huang H, Dai L, Qi S, Li J, Colak G, Chen Y, Xia C, Peng C, Ruan H, Kirkey M, Wang D, Jensen LM, Kwon OK, Lee S, Pletcher SD, Tan M, Lombard DB, White KP, Zhao H, Li J, Roeder RG, Yang X, Zhao Y: Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation. Mol Cell. 2016 Apr 21. PMID: 27105115

Patel JM, Knopf J, Reiner E, Bossuyt V, Epstein L, DiGiovanna M, Chung G, Silber A, Sanft T, Hofstatter E, Mougalian S, Abu-Khalaf M, Platt J, Shi W, Gershkovich P, Hatzis C, Pusztai L: Mutation based treatment recommendations from next generation sequencing data: a comparison of web tools. Oncotarget. 2016 Apr 19. PMID: 26980737

Balko JM, Schwarz LJ, Luo N, Estrada MV, Giltnane JM, Dávila-González D, Wang K, Sánchez V, Dean PT, Combs SE, Hicks D, Pinto JA, Landis MD, Doimi FD, Yelensky R, Miller VA, Stephens PJ, Rimm DL, Gómez H, Chang JC, Sanders ME, Cook RS, Arteaga CL: Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence. Sci Transl Med. 2016 Apr 13. PMID: 27075627

Freed DM, Park JH, Radhakrishnan R, Lemmon MA: Deletion Mutations Keep Kinase Inhibitors in the Loop. Cancer Cell. 2016 Apr 11. PMID: 27070691

Henderson MX, Wirak GS, Zhang YQ, Dai F, Ginsberg SD, Dolzhanskaya N, Staropoli JF, Nijssen PC, Lam TT, Roth AF, Davis NG, Dawson G, Velinov M, Chandra SS: Neuronal ceroid lipofuscinosis with DNAJC5/CSPα mutation has PPT1 pathology and exhibit aberrant protein palmitoylation. Acta Neuropathol. 2016 Apr; 2015 Dec 10. PMID: 26659577

Hser YI, Evans E, Huang D, Weiss R, Saxon A, Carroll KM, Woody G, Liu D, Wakim P, Matthews AG, Hatch-Maillette M, Jelstrom E, Wiest K, McLaughlin P, Ling W: Long-term outcomes after randomization to buprenorphine/naloxone versus methadone in a multi-site trial. Addiction. 2016 Apr; 2016 Jan 13. PMID: 26599131

Hu R, Hochstrasser M: Recent progress in ubiquitin and ubiquitin-like protein (Ubl) signaling. Cell Res. 2016 Apr. PMID: 27033807

Ronau JA, Beckmann JF, Hochstrasser M: Substrate specificity of the ubiquitin and Ubl proteases. Cell Res. 2016 Apr; 2016 Mar 25. PMID: 27012468

Flannery CA, Rowzee AM, Choe GH, Saleh FL, Radford CC, Taylor HS, Wood TL: Development of a Quantitative PCR Assay for Detection of Human Insulin-Like Growth Factor Receptor and Insulin Receptor Isoforms. Endocrinology. 2016 Apr; 2016 Feb 10. PMID: 26862994

Kobashigawa Y, Amano S, Yoza K, Himeno R, Amemiya S, Morioka H, Yokogawa M, Kumeta H, Schlessinger J, Inagaki F: Nuclear magnetic resonance analysis of the conformational state of cancer mutant of fibroblast growth factor receptor 1 tyrosine kinase domain. Genes Cells. 2016 Apr; 2016 Feb 10. PMID: 26864631

Gillies J, Hickey CM, Su D, Wu Z, Peng J, Hochstrasser M: SUMO Pathway Modulation of Regulatory Protein Binding at the Ribosomal DNA Locus in Saccharomyces cerevisiae. Genetics. 2016 Apr; 2016 Feb 2. PMID: 26837752

Torres R, Velazquez H, Chang JJ, Levene MJ, Moeckel G, Desir GV, Safirstein R: Three-Dimensional Morphology by Multiphoton Microscopy with Clearing in a Model of Cisplatin-Induced CKD. J Am Soc Nephrol. 2016 Apr; 2015 Aug 24. PMID: 26303068

Zhu M, Sun BH, Saar K, Simpson C, Troiano N, Dallas SL, Tiede-Lewis LM, Nevius E, Pereira JP, Weinstein RS, Tommasini SM, Insogna KL: Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo. J Bone Miner Res. 2016 Apr; 2015 Nov 18. PMID: 26496249

Chan PY, Carrera Silva EA, De Kouchkovsky D, Joannas LD, Hao L, Hu D, Huntsman S, Eng C, Licona-Limón P, Weinstein JS, Herbert DR, Craft JE, Flavell RA, Repetto S, Correale J, Burchard EG, Torgerson DG, Ghosh S, Rothlin CV: The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity. Science. 2016 Apr 1. PMID: 27034374

Padmanabhan A, Vuong SA, Hochstrasser M: Assembly of an Evolutionarily Conserved Alternative Proteasome Isoform in Human Cells. Cell Rep. 2016 Mar 29; 2016 Mar 22. PMID: 26997268

Chen Y, Zhang H, Zhou HJ, Ji W, Min W: Mitochondrial Redox Signaling and Tumor Progression. Cancers (Basel). 2016 Mar 25; 2016 Mar 25. PMID: 27023612

Shao L, Feng B, Zhang Y, Zhou H, Ji W, Min W: The role of adipose-derived inflammatory cytokines in type 1 diabetes. Adipocyte. 2016 Jul-Sep; 2016 Mar 17. PMID: 27617172

Wang X, Chen M, Yu X, Pornputtapong N, Chen H, Zhang NR, Powers RS, Krauthammer M: Global copy number profiling of cancer genomes. Bioinformatics. 2016 Mar 15; 2015 Nov 16. PMID: 26576652

Loi S, Dushyanthen S, Beavis PA, Salgado R, Denkert C, Savas P, Combs S, Rimm DL, Giltnane JM, Estrada MV, Sánchez V, Sanders ME, Cook RS, Pilkinton MA, Mallal SA, Wang K, Miller VA, Stephens PJ, Yelensky R, Doimi FD, Gómez H, Ryzhov SV, Darcy PK, Arteaga CL, Balko JM: RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors. Clin Cancer Res. 2016 Mar 15; 2015 Oct 29. PMID: 26515496

Guo X, Hollander L, MacPherson D, Wang L, Velazquez H, Chang J, Safirstein R, Cha C, Gorelick F, Desir GV: Inhibition of renalase expression and signaling has antitumor activity in pancreatic cancer. Sci Rep. 2016 Mar 14; 2016 Mar 14. PMID: 26972355

Huber EM, Heinemeyer W, Li X, Arendt CS, Hochstrasser M, Groll M: A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome. Nat Commun. 2016 Mar 11; 2016 Mar 11. PMID: 26964885

Xin T, Greco V, Myung P: Hardwiring Stem Cell Communication through Tissue Structure. Cell. 2016 Mar 10. PMID: 26967287

Lemmon MA, Freed DM, Schlessinger J, Kiyatkin A: The Dark Side of Cell Signaling: Positive Roles for Negative Regulators. Cell. 2016 Mar 10. PMID: 26967284

Brenner MD, Zhou R, Conway DE, Lanzano L, Gratton E, Schwartz MA, Ha T: Spider Silk Peptide Is a Compact, Linear Nanospring Ideal for Intracellular Tension Sensing. Nano Lett. 2016 Mar 9; 2016 Feb 3. PMID: 26824190

Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Fromme JC, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P: Data publication with the structural biology data grid supports live analysis. Nat Commun. 2016 Mar 7; 2016 Mar 7. PMID: 26947396

Neckman JP, Kim J, Mathur M, Myung P, Girardi M: Diverse cutaneous manifestations of Erdheim-Chester disease in a woman with a history of Langerhans cell histiocytosis. JAAD Case Rep. 2016 Mar; 2016 Mar 5. PMID: 27051852

Bottanelli F, Kromann EB, Allgeyer ES, Erdmann RS, Wood Baguley S, Sirinakis G, Schepartz A, Baddeley D, Toomre DK, Rothman JE, Bewersdorf J: Two-colour live-cell nanoscale imaging of intracellular targets. Nat Commun. 2016 Mar 4; 2016 Mar 4. PMID: 26940217

Srivastava A, Shinn AS, Lam TT, Lee PJ, Mannam P: SILAC based protein profiling data of MKK3 knockout mouse embryonic fibroblasts. Data Brief. 2016 Jun; 2016 Mar 2. PMID: 26977448

Liu D, Lei L, Desir M, Huang Y, Cleman J, Jiang W, Fernandez-Hernando C, Di Lorenzo A, Sessa WC, Giordano FJ: Smooth Muscle Hypoxia-Inducible Factor 1α Links Intravascular Pressure and Atherosclerosis--Brief Report. Arterioscler Thromb Vasc Biol. 2016 Mar; 2016 Jan 21. PMID: 26800562

Rotllan N, Price N, Pati P, Goedeke L, Fernández-Hernando C: microRNAs in lipoprotein metabolism and cardiometabolic disorders. Atherosclerosis. 2016 Mar; 2016 Jan 18. PMID: 26828754

Schwantes-An TH, Zhang J, Chen LS, Hartz SM, Culverhouse RC, Chen X, Coon H, Frank J, Kamens HM, Konte B, Kovanen L, Latvala A, Legrand LN, Maher BS, Melroy WE, Nelson EC, Reid MW, Robinson JD, Shen PH, Yang BZ, Andrews JA, Aveyard P, Beltcheva O, Brown SA, Cannon DS, Cichon S, Corley RP, Dahmen N, Degenhardt L, Foroud T, Gaebel W, Giegling I, Glatt SJ, Grucza RA, Hardin J, Hartmann AM, Heath AC, Herms S, Hodgkinson CA, Hoffmann P, Hops H, Huizinga D, Ising M, Johnson EO, Johnstone E, Kaneva RP, Kendler KS, Kiefer F, Kranzler HR, Krauter KS, Levran O, Lucae S, Lynskey MT, Maier W, Mann K, Martin NG, Mattheisen M, Montgomery GW, Müller-Myhsok B, Murphy MF, Neale MC, Nikolov MA, Nishita D, Nöthen MM, Nurnberger J, Partonen T, Pergadia ML, Reynolds M, Ridinger M, Rose RJ, Rouvinen-Lagerström N, Scherbaum N, Schmäl C, Soyka M, Stallings MC, Steffens M, Treutlein J, Tsuang M, Wall TL, Wodarz N, Yuferov V, Zill P, Bergen AW, Chen J, Cinciripini PM, Edenberg HJ, Ehringer MA, Ferrell RE, Gelernter J, Goldman D, Hewitt JK, Hopfer CJ, Iacono WG, Kaprio J, Kreek MJ, Kremensky IM, Madden PA, McGue M, Munafò MR, Philibert RA, Rietschel M, Roy A, Rujescu D, Saarikoski ST, Swan GE, Todorov AA, Vanyukov MM, Weiss RB, Bierut LJ, Saccone NL: Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts. Behav Genet. 2016 Mar; 2015 Sep 21. PMID: 26392368

Combs SE, Han G, Mani N, Beruti S, Nerenberg M, Rimm DL: Loss of antigenicity with tissue age in breast cancer. Lab Invest. 2016 Mar; 2015 Nov 16. PMID: 26568292

Zhao ZM, Zhao B, Bai Y, Iamarino A, Gaffney SG, Schlessinger J, Lifton RP, Rimm DL, Townsend JP: Early and multiple origins of metastatic lineages within primary tumors. Proc Natl Acad Sci U S A. 2016 Feb 23; 2016 Feb 8. PMID: 26858460

Noren DP, Chou WH, Lee SH, Qutub AA, Warmflash A, Wagner DS, Popel AS, Levchenko A: Endothelial cells decode VEGF-mediated Ca2+ signaling patterns to produce distinct functional responses. Sci Signal. 2016 Feb 23; 2016 Feb 23. PMID: 26905425

Adams BD, Wali VB, Cheng CJ, Inukai S, Booth CJ, Agarwal S, Rimm DL, Győrffy B, Santarpia L, Pusztai L, Saltzman WM, Slack FJ: miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer. Cancer Res. 2016 Feb 15; 2015 Dec 16. PMID: 26676753

Ellison D, Mugler A, Brennan MD, Lee SH, Huebner RJ, Shamir ER, Woo LA, Kim J, Amar P, Nemenman I, Ewald AJ, Levchenko A: Cell-cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis. Proc Natl Acad Sci U S A. 2016 Feb 9; 2016 Jan 20. PMID: 26792522

Mugler A, Levchenko A, Nemenman I: Limits to the precision of gradient sensing with spatial communication and temporal integration. Proc Natl Acad Sci U S A. 2016 Feb 9; 2016 Jan 20. PMID: 26792517

Huang X, Stern DF, Zhao H: Transcriptional Profiles from Paired Normal Samples Offer Complementary Information on Cancer Patient Survival--Evidence from TCGA Pan-Cancer Data. Sci Rep. 2016 Feb 3; 2016 Feb 3. PMID: 26837275

Knobf MT, Jeon S, Smith B, Harris L, Kerstetter J, Thompson AS, Insogna K: Effect of a randomized controlled exercise trial on bone outcomes: influence of adjuvant endocrine therapy. Breast Cancer Res Treat. 2016 Feb; 2016 Feb 5. PMID: 26850265

Vassilakopoulou M, Avgeris M, Velcheti V, Kotoula V, Rampias T, Chatzopoulos K, Perisanidis C, Kontos CK, Giotakis AI, Scorilas A, Rimm D, Sasaki C, Fountzilas G, Psyrri A: Evaluation of PD-L1 Expression and Associated Tumor-Infiltrating Lymphocytes in Laryngeal Squamous Cell Carcinoma. Clin Cancer Res. 2016 Feb 1; 2015 Sep 25. PMID: 26408403

Kim JH, Kwon SJ, Stankewich MC, Huh GY, Glantz SB, Morrow JS: Reactive protoplasmic and fibrous astrocytes contain high levels of calpain-cleaved alpha 2 spectrin. Exp Mol Pathol. 2016 Feb; 2015 Nov 10. PMID: 26551084

Molitoris JM, Paliwal S, Sekar RB, Blake R, Park J, Trayanova NA, Tung L, Levchenko A: Precisely parameterized experimental and computational models of tissue organization. Integr Biol (Camb). 2016 Feb; 2016 Jan 29. PMID: 26822672

Zhang X, Imel EA, Ruppe MD, Weber TJ, Klausner MA, Ito T, Vergeire M, Humphrey J, Glorieux FH, Portale AA, Insogna K, Carpenter TO, Peacock M: Pharmacokinetics and pharmacodynamics of a human monoclonal anti-FGF23 antibody (KRN23) in the first multiple ascending-dose trial treating adults with X-linked hypophosphatemia. J Clin Pharmacol. 2016 Feb; 2015 Aug 11. PMID: 26073451

Price NL, Holtrup B, Kwei SL, Wabitsch M, Rodeheffer M, Bianchini L, Suárez Y, Fernández-Hernando C: SREBP-1c/MicroRNA 33b Genomic Loci Control Adipocyte Differentiation. Mol Cell Biol. 2016 Feb 1; 2016 Feb 1. PMID: 26830228

Dubrac A, Genet G, Ola R, Zhang F, Pibouin-Fragner L, Han J, Zhang J, Thomas JL, Chedotal A, Schwartz MA, Eichmann A: Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neovascularization. Circulation. 2016 Jan 26; 2015 Dec 9. PMID: 26659946

Li X, Li Y, Arendt CS, Hochstrasser M: Distinct Elements in the Proteasomal β5 Subunit Propeptide Required for Autocatalytic Processing and Proteasome Assembly. J Biol Chem. 2016 Jan 22; 2015 Dec 1. PMID: 26627836

Jeong J, VanHouten JN, Dann P, Kim W, Sullivan C, Yu H, Liotta L, Espina V, Stern DF, Friedman PA, Wysolmerski JJ: PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer. Proc Natl Acad Sci U S A. 2016 Jan 19; 2016 Jan 4. PMID: 26729871

Pirazzoli V, Ayeni D, Meador CB, Sanganahalli BG, Hyder F, de Stanchina E, Goldberg SB, Pao W, Politi K: Afatinib plus Cetuximab Delays Resistance Compared to Single-Agent Erlotinib or Afatinib in Mouse Models of TKI-Naïve EGFR L858R-Induced Lung Adenocarcinoma. Clin Cancer Res. 2016 Jan 15; 2015 Sep 4. PMID: 26341921

Wilson MA, Zhao F, Khare S, Roszik J, Woodman SE, D'Andrea K, Wubbenhorst B, Rimm DL, Kirkwood JM, Kluger HM, Schuchter LM, Lee SJ, Flaherty KT, Nathanson KL: Copy Number Changes Are Associated with Response to Treatment with Carboplatin, Paclitaxel, and Sorafenib in Melanoma. Clin Cancer Res. 2016 Jan 15; 2015 Aug 25. PMID: 26307133

Morse EM, Sun X, Olberding JR, Ha BH, Boggon TJ, Calderwood DA: PAK6 targets to cell-cell adhesions through its N-terminus in a Cdc42-dependent manner to drive epithelial colony escape. J Cell Sci. 2016 Jan 15; 2015 Nov 23. PMID: 26598554

Chamorro-Jorganes A, Lee MY, Araldi E, Landskroner-Eiger S, Fernández-Fuertes M, Sahraei M, Quiles Del Rey M, van Solingen C, Yu J, Fernández-Hernando C, Sessa WC, Suárez Y: VEGF-Induced Expression of miR-17-92 Cluster in Endothelial Cells Is Mediated by ERK/ELK1 Activation and Regulates Angiogenesis. Circ Res. 2016 Jan 8; 2015 Oct 15. PMID: 26472816

Stankewich MC, Moeckel GW, Ji L, Ardito T, Morrow JS: Isoforms of Spectrin and Ankyrin Reflect the Functional Topography of the Mouse Kidney. PLoS One. 2016; 2016 Jan 4. PMID: 26727517

Bartlett JM, Christiansen J, Gustavson M, Rimm DL, Piper T, van de Velde CJ, Hasenburg A, Kieback DG, Putter H, Markopoulos CJ, Dirix LY, Seynaeve C, Rea DW: Validation of the IHC4 Breast Cancer Prognostic Algorithm Using Multiple Approaches on the Multinational TEAM Clinical Trial. Arch Pathol Lab Med. 2016 Jan. PMID: 26717057

Goldberg AB, Turk BE: Inhibitors of the Metalloproteinase Anthrax Lethal Factor. Curr Top Med Chem. 2016. PMID: 27072692

Cuttano R, Rudini N, Bravi L, Corada M, Giampietro C, Papa E, Morini MF, Maddaluno L, Baeyens N, Adams RH, Jain MK, Owens GK, Schwartz M, Lampugnani MG, Dejana E: KLF4 is a key determinant in the development and progression of cerebral cavernous malformations. EMBO Mol Med. 2016 Jan 1. PMID: 26612856

Mohler JL, Armstrong AJ, Bahnson RR, D'Amico AV, Davis BJ, Eastham JA, Enke CA, Farrington TA, Higano CS, Horwitz EM, Hurwitz M, Kane CJ, Kawachi MH, Kuettel M, Lee RJ, Meeks JJ, Penson DF, Plimack ER, Pow-Sang JM, Raben D, Richey S, Roach M 3rd, Rosenfeld S, Schaeffer E, Skolarus TA, Small EJ, Sonpavde G, Srinivas S, Strope SA, Tward J, Shead DA, Freedman-Cass DA: Prostate Cancer, Version 1.2016. J Natl Compr Canc Netw. 2016 Jan. PMID: 26733552

McLaughlin J, Han G, Schalper KA, Carvajal-Hausdorf D, Pelekanou V, Rehman J, Velcheti V, Herbst R, LoRusso P, Rimm DL: Quantitative Assessment of the Heterogeneity of PD-L1 Expression in Non-Small-Cell Lung Cancer. JAMA Oncol. 2016 Jan. PMID: 26562159

Wilson NR, Hochstrasser M: The Regulation of Chromatin by Dynamic SUMO Modifications. Methods Mol Biol. 2016. PMID: 27631795

Chen JJ, Kwak M, Fan R: Single-Cell Cytokine Profiling to Investigate Cellular Functional Diversity in Hematopoietic Malignancies. Methods Mol Biol. 2016. PMID: 27581152

Miller CJ, Turk BE: Rapid Identification of Protein Kinase Phosphorylation Site Motifs Using Combinatorial Peptide Libraries. Methods Mol Biol. 2016. PMID: 26501912

Deng Y, Turk BE: Analysis of Protein Tyrosine Kinase Specificity Using Positional Scanning Peptide Microarrays. Methods Mol Biol. 2016. PMID: 26490465

Baeyens N, Schwartz MA: Biomechanics of vascular mechanosensation and remodeling. Mol Biol Cell. 2016 Jan 1. PMID: 26715421

Norton PA, Nager CW, Brubaker L, Lemack GE, Sirls LT, Holley R, Chai TC, Kraus SR, Zyczynski H, Smith B, Stoddard A, Urinary Incontinence Treatment Network.: The cost of preoperative urodynamics: A secondary analysis of the ValUE trial. Neurourol Urodyn. 2016 Jan; 2014 Oct 18. PMID: 25327775

Vyas M, Zhang X, Morrow JS, Jain D, Salem RR, West AB: Focal hepatic glycogenosis associated with metastatic insulinoma presenting as mass lesions. Pathol Res Pract. 2016 Jan; 2015 Nov 26. PMID: 26627264

Cantley LG, Colangelo CM, Stone KL, Chung L, Belcher J, Abbott T, Cantley JL, Williams KR, Parikh CR: Development of a Targeted Urine Proteome Assay for kidney diseases. Proteomics Clin Appl. 2016 Jan; 2015 Oct 6. PMID: 26220717

Reshetnyak AV, Murray PB, Shi X, Mo ES, Mohanty J, Tome F, Bai H, Gunel M, Lax I, Schlessinger J: Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand-receptor interactions. Proc Natl Acad Sci U S A. 2015 Dec 29; 2015 Nov 16. PMID: 26630010

Calderwood DA: The Rap1-RIAM pathway prefers β2 integrins. Blood. 2015 Dec 17. PMID: 26679542

Gamo NJ, Lur G, Higley MJ, Wang M, Paspalas CD, Vijayraghavan S, Yang Y, Ramos BP, Peng K, Kata A, Boven L, Lin F, Roman L, Lee D, Arnsten AF: Stress Impairs Prefrontal Cortical Function via D1 Dopamine Receptor Interactions With Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels. Biol Psychiatry. 2015 Dec 15; 2015 Feb 4. PMID: 25731884

Pesta DH, Perry RJ, Guebre-Egziabher F, Zhang D, Jurczak M, Fischer-Rosinsky A, Daniels MA, Willmes DM, Bhanot S, Bornstein SR, Knauf F, Samuel VT, Shulman GI, Birkenfeld AL: Prevention of diet-induced hepatic steatosis and hepatic insulin resistance by second generation antisense oligonucleotides targeted to the longevity gene mIndy (Slc13a5). Aging (Albany NY). 2015 Dec. PMID: 26647160

Goedeke L, Rotllan N, Ramírez CM, Aranda JF, Canfrán-Duque A, Araldi E, Fernández-Hernando A, Langhi C, de Cabo R, Baldán Á, Suárez Y, Fernández-Hernando C: miR-27b inhibits LDLR and ABCA1 expression but does not influence plasma and hepatic lipid levels in mice. Atherosclerosis. 2015 Dec. PMID: 26520906

Holford ME, Krauthammer M: Mutadelic: mutation analysis using description logic inferencing capabilities. Bioinformatics. 2015 Dec 1; 2015 Aug 12. PMID: 26272983

Sanft T, Aktas B, Schroeder B, Bossuyt V, DiGiovanna M, Abu-Khalaf M, Chung G, Silber A, Hofstatter E, Mougalian S, Epstein L, Hatzis C, Schnabel C, Pusztai L: Prospective assessment of the decision-making impact of the Breast Cancer Index in recommending extended adjuvant endocrine therapy for patients with early-stage ER-positive breast cancer. Breast Cancer Res Treat. 2015 Dec; 2015 Nov 14. PMID: 26578401

Zhang R, Li X, Boggon TJ: Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interface. J Struct Biol. 2015 Dec; 2015 Oct 14. PMID: 26458359

Crawford ED, Higano CS, Shore ND, Hussain M, Petrylak DP: Treating Patients with Metastatic Castration Resistant Prostate Cancer: A Comprehensive Review of Available Therapies. J Urol. 2015 Dec; 2015 Jul 18. PMID: 26196735

Fang LQ, Liu K, Li XL, Liang S, Yang Y, Yao HW, Sun RX, Sun Y, Chen WJ, Zuo SQ, Ma MJ, Li H, Jiang JF, Liu W, Yang XF, Gray GC, Krause PJ, Cao WC: Emerging tick-borne infections in mainland China: an increasing public health threat. Lancet Infect Dis. 2015 Dec; 2015 Oct 6. PMID: 26453241

Shao L, Zhou HJ, Zhang H, Qin L, Hwa J, Yun Z, Ji W, Min W: SENP1-mediated NEMO deSUMOylation in adipocytes limits inflammatory responses and type-1 diabetes progression. Nat Commun. 2015 Nov 24; 2015 Nov 24. PMID: 26596471

Shi H, Gatzke F, Molle JM, Lee HB, Helm ET, Oldham JJ, Zhang L, Gerrard DE, Bennett AM: Mice lacking MKP-1 and MKP-5 Reveal Hierarchical Regulation of Regenerative Myogenesis. J Stem Cell Regen Biol. 2015 Nov 12. PMID: 27064463

Kwak M, Han L, Chen JJ, Fan R: Interfacing Inorganic Nanowire Arrays and Living Cells for Cellular Function Analysis. Small. 2015 Nov 11; 2015 Sep 9. PMID: 26349637

Espinosa-Diez C, Fierro-Fernández M, Sánchez-Gómez F, Rodríguez-Pascual F, Alique M, Ruiz-Ortega M, Beraza N, Martínez-Chantar ML, Fernández-Hernando C, Lamas S: Targeting of Gamma-Glutamyl-Cysteine Ligase by miR-433 Reduces Glutathione Biosynthesis and Promotes TGF-β-Dependent Fibrogenesis. Antioxid Redox Signal. 2015 Nov 10; 2015 Jan 9. PMID: 25353619

Langdon CG, Wiedemann N, Held MA, Mamillapalli R, Iyidogan P, Theodosakis N, Platt JT, Levy F, Vuagniaux G, Wang S, Bosenberg MW, Stern DF: SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells. Oncotarget. 2015 Nov 10. PMID: 26485762

Kim J, Yoon H, Horie T, Burchett JM, Restivo JL, Rotllan N, Ramírez CM, Verghese PB, Ihara M, Hoe HS, Esau C, Fernández-Hernando C, Holtzman DM, Cirrito JR, Ono K, Kim J: microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain. J Neurosci. 2015 Nov 4. PMID: 26538644

Alves TC, Pongratz RL, Zhao X, Yarborough O, Sereda S, Shirihai O, Cline GW, Mason G, Kibbey RG: Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle. Cell Metab. 2015 Nov 3; 2015 Sep 24. PMID: 26411341

Haskins JW, Zhang S, Means RE, Kelleher JK, Cline GW, Canfrán-Duque A, Suárez Y, Stern DF: Neuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptake. Sci Signal. 2015 Nov 3; 2015 Nov 3. PMID: 26535009

Ebmeier S, Horsley V: Origin of fibrosing cells in systemic sclerosis. Curr Opin Rheumatol. 2015 Nov. PMID: 26352735

Alexander CM, Kasza I, Yen CL, Reeder SB, Hernando D, Gallo RL, Jahoda CA, Horsley V, MacDougald OA: Dermal white adipose tissue: a new component of the thermogenic response. J Lipid Res. 2015 Nov; 2015 Sep 24. PMID: 26405076

Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, Mitsche M, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Hurwitz SJ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Lei Q, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J: 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov; 2015 Oct 19. PMID: 26479318

Wagschal A, Najafi-Shoushtari SH, Wang L, Goedeke L, Sinha S, deLemos AS, Black JC, Ramírez CM, Li Y, Tewhey R, Hatoum I, Shah N, Lu Y, Kristo F, Psychogios N, Vrbanac V, Lu YC, Hla T, de Cabo R, Tsang JS, Schadt E, Sabeti PC, Kathiresan S, Cohen DE, Whetstine J, Chung RT, Fernández-Hernando C, Kaplan LM, Bernards A, Gerszten RE, Näär AM: Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis. Nat Med. 2015 Nov; 2015 Oct 26. PMID: 26501192

Goedeke L, Rotllan N, Canfrán-Duque A, Aranda JF, Ramírez CM, Araldi E, Lin CS, Anderson NN, Wagschal A, de Cabo R, Horton JD, Lasunción MA, Näär AM, Suárez Y, Fernández-Hernando C: MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels. Nat Med. 2015 Nov; 2015 Oct 5. PMID: 26437365

Holmström F, Shimizu S, Shimizu T, Higashi Y, Martin DT, Honda M, Saito M: Protective effect of hydroxyfasudil, a Rho kinase inhibitor, on ventral prostatic hyperplasia in the spontaneously hypertensive rat. Prostate. 2015 Nov; 2015 Aug 19. PMID: 26286428

Lee S, Greenlee EB, Amick JR, Ligon GF, Lillquist JS, Natoli EJ Jr, Hadari Y, Alvarado D, Schlessinger J: Inhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration. Proc Natl Acad Sci U S A. 2015 Oct 27; 2015 Oct 12. PMID: 26460020

Stoops EH, Hull M, Olesen C, Mistry K, Harder JL, Rivera-Molina F, Toomre D, Caplan MJ: The periciliary ring in polarized epithelial cells is a hot spot for delivery of the apical protein gp135. J Cell Biol. 2015 Oct 26. PMID: 26504168

Li X, Fisher OS, Boggon TJ: The cerebral cavernous malformations proteins. Oncotarget. 2015 Oct 20. PMID: 26356566

Vatner DF, Snikeris J, Popov V, Perry RJ, Rahimi Y, Samuel VT: 3,5 Diiodo-L-Thyronine (T2) Does Not Prevent Hepatic Steatosis or Insulin Resistance in Fat-Fed Sprague Dawley Rats. PLoS One. 2015; 2015 Oct 20. PMID: 26485433

Goldstein J, Roth E, Roberts N, Zwick R, Lin S, Fletcher S, Tadeu A, Wu C, Beck A, Zeiss C, Suárez-Fariñas M, Horsley V: Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis. Mol Biol Cell. 2015 Oct 15; 2015 Aug 26. PMID: 26310443

Tomko RJ Jr, Taylor DW, Chen ZA, Wang HW, Rappsilber J, Hochstrasser M: A Single α Helix Drives Extensive Remodeling of the Proteasome Lid and Completion of Regulatory Particle Assembly. Cell. 2015 Oct 8. PMID: 26451487

Kim JG, Sun BH, Dietrich MO, Koch M, Yao GQ, Diano S, Insogna K, Horvath TL: AgRP Neurons Regulate Bone Mass. Cell Rep. 2015 Oct 6; 2015 Sep 24. PMID: 26411686

Qi C, Wang L, Zhang M, Shao X, Chang X, Fan Z, Cao Q, Mou S, Wang Q, Yan Y, Desir G, Ni Z: Serum Renalase Levels Correlate with Disease Activity in Lupus Nephritis. PLoS One. 2015; 2015 Oct 2. PMID: 26431044

Hurwitz M: Chemotherapy in Prostate Cancer. Curr Oncol Rep. 2015 Oct. PMID: 26216506

Iwamoto DV, Calderwood DA: Regulation of integrin-mediated adhesions. Curr Opin Cell Biol. 2015 Oct; 2015 Jul 17. PMID: 26189062

Srivastava A, McGinniss J, Wong Y, Shinn AS, Lam TT, Lee PJ, Mannam P: MKK3 deletion improves mitochondrial quality. Free Radic Biol Med. 2015 Oct; 2015 Jun 25. PMID: 26119780

Kobashigawa Y, Amano S, Yokogawa M, Kumeta H, Morioka H, Inouye M, Schlessinger J, Inagaki F: Structural analysis of the mechanism of phosphorylation of a critical autoregulatory tyrosine residue in FGFR1 kinase domain. Genes Cells. 2015 Oct; 2015 Aug 24. PMID: 26300540

Connor J, Olear EA, Insogna KL, Katz L, Baker S, Kaur R, Simpson CA, Sterpka J, Dubrow R, Zhang JH, Carpenter TO: Conventional Therapy in Adults With X-Linked Hypophosphatemia: Effects on Enthesopathy and Dental Disease. J Clin Endocrinol Metab. 2015 Oct; 2015 Jul 15. PMID: 26176801

Hickey CM, Hochstrasser M: STUbL-mediated degradation of the transcription factor MATα2 requires degradation elements that coincide with corepressor binding sites. Mol Biol Cell. 2015 Oct 1; 2015 Aug 5. PMID: 26246605

Gromova I, Gromov P, Honma N, Kumar S, Rimm D, Talman ML, Wielenga VT, Moreira JM: High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy. Mol Oncol. 2015 Oct; 2015 May 14. PMID: 26026368

Agarwal D, Qi Y, Jiang T, Liu X, Shi W, Wali VB, Turk B, Ross JS, Fraser Symmans W, Pusztai L, Hatzis C: Characterization of DNA variants in the human kinome in breast cancer. Sci Rep. 2015 Sep 30; 2015 Sep 30. PMID: 26420498

Yang X, Ruan HB: Neuronal Control of Adaptive Thermogenesis. Front Endocrinol (Lausanne). 2015; 2015 Sep 25. PMID: 26441839

Creixell P, Palmeri A, Miller CJ, Lou HJ, Santini CC, Nielsen M, Turk BE, Linding R: Unmasking determinants of specificity in the human kinome. Cell. 2015 Sep 24; 2015 Sep 17. PMID: 26388442

Creixell P, Schoof EM, Simpson CD, Longden J, Miller CJ, Lou HJ, Perryman L, Cox TR, Zivanovic N, Palmeri A, Wesolowska-Andersen A, Helmer-Citterich M, Ferkinghoff-Borg J, Itamochi H, Bodenmiller B, Erler JT, Turk BE, Linding R: Kinome-wide decoding of network-attacking mutations rewiring cancer signaling. Cell. 2015 Sep 24; 2015 Sep 17. PMID: 26388441

Rosowski KA, Mertz AF, Norcross S, Dufresne ER, Horsley V: Edges of human embryonic stem cell colonies display distinct mechanical properties and differentiation potential. Sci Rep. 2015 Sep 22; 2015 Sep 22. PMID: 26391588

Katrancha SM, Koleske AJ: SNARE Complex Dysfunction: A Unifying Hypothesis for Schizophrenia. Biol Psychiatry. 2015 Sep 15. PMID: 26296424

Ho PC, Bihuniak JD, Macintyre AN, Staron M, Liu X, Amezquita R, Tsui YC, Cui G, Micevic G, Perales JC, Kleinstein SH, Abel ED, Insogna KL, Feske S, Locasale JW, Bosenberg MW, Rathmell JC, Kaech SM: Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses. Cell. 2015 Sep 10; 2015 Aug 27. PMID: 26321681

Petersen KF, Morino K, Alves TC, Kibbey RG, Dufour S, Sono S, Yoo PS, Cline GW, Shulman GI: Effect of aging on muscle mitochondrial substrate utilization in humans. Proc Natl Acad Sci U S A. 2015 Sep 8; 2015 Aug 24. PMID: 26305973

Li Q, Tsuneki M, Krauthammer M, Couture R, Schwartz M, Madri JA: Modulation of Sox10, HIF-1α, Survivin, and YAP by Minocycline in the Treatment of Neurodevelopmental Handicaps following Hypoxic Insult. Am J Pathol. 2015 Sep; 2015 Jul 22. PMID: 26209807

Martín Sánchez C, Pérez Martín JM, Jin JS, Dávalos A, Zhang W, de la Peña G, Martínez-Botas J, Rodríguez-Acebes S, Suárez Y, Hazen MJ, Gómez-Coronado D, Busto R, Cheng YC, Lasunción MA: Disruption of the mevalonate pathway induces dNTP depletion and DNA damage. Biochim Biophys Acta. 2015 Sep; 2015 Jun 5. PMID: 26055626

Ji W, Li Y, He Y, Yin M, Zhou HJ, Boggon TJ, Zhang H, Min W: AIP1 Expression in Tumor Niche Suppresses Tumor Progression and Metastasis. Cancer Res. 2015 Sep 1; 2015 Jul 2. PMID: 26139244

Ayeni D, Politi K, Goldberg SB: Emerging Agents and New Mutations in EGFR-Mutant Lung Cancer. Clin Cancer Res. 2015 Sep 1; 2015 Jul 13. PMID: 26169963

Lupsa BC, Insogna K: Bone Health and Osteoporosis. Endocrinol Metab Clin North Am. 2015 Sep. PMID: 26316240

Aranda JF, Canfrán-Duque A, Goedeke L, Suárez Y, Fernández-Hernando C: The miR-199-dynamin regulatory axis controls receptor-mediated endocytosis. J Cell Sci. 2015 Sep 1; 2015 Jul 10. PMID: 26163491

Yaniv Y, Ganesan A, Yang D, Ziman BD, Lyashkov AE, Levchenko A, Zhang J, Lakatta EG: Real-time relationship between PKA biochemical signal network dynamics and increased action potential firing rate in heart pacemaker cells: Kinetics of PKA activation in heart pacemaker cells. J Mol Cell Cardiol. 2015 Sep; 2015 Aug 1. PMID: 26241846

Daimiel-Ruiz L, Klett-Mingo M, Konstantinidou V, Micó V, Aranda JF, García B, Martínez-Botas J, Dávalos A, Fernández-Hernando C, Ordovás JM: Dietary lipids modulate the expression of miR-107, a miRNA that regulates the circadian system. Mol Nutr Food Res. 2015 Sep. PMID: 26387852

Krauthammer M, Kong Y, Bacchiocchi A, Evans P, Pornputtapong N, Wu C, McCusker JP, Ma S, Cheng E, Straub R, Serin M, Bosenberg M, Ariyan S, Narayan D, Sznol M, Kluger HM, Mane S, Schlessinger J, Lifton RP, Halaban R: Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas. Nat Genet. 2015 Sep; 2015 Jul 27. PMID: 26214590

Choi J, Goh G, Walradt T, Hong BS, Bunick CG, Chen K, Bjornson RD, Maman Y, Wang T, Tordoff J, Carlson K, Overton JD, Liu KJ, Lewis JM, Devine L, Barbarotta L, Foss FM, Subtil A, Vonderheid EC, Edelson RL, Schatz DG, Boggon TJ, Girardi M, Lifton RP: Genomic landscape of cutaneous T cell lymphoma. Nat Genet. 2015 Sep; 2015 Jul 20. PMID: 26192916

Shimizu S, Shimizu T, Tsounapi P, Higashi Y, Martin DT, Nakamura K, Honda M, Inoue K, Saito M: Effect of Silodosin, an Alpha1A-Adrenoceptor Antagonist, on Ventral Prostatic Hyperplasia in the Spontaneously Hypertensive Rat. PLoS One. 2015; 2015 Aug 26. PMID: 26308715

Ronkina N, Johansen C, Bohlmann L, Lafera J, Menon MB, Tiedje C, Laaß K, Turk BE, Iversen L, Kotlyarov A, Gaestel M: Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK. PLoS One. 2015; 2015 Aug 21. PMID: 26295581

Kang HB, Fan J, Lin R, Elf S, Ji Q, Zhao L, Jin L, Seo JH, Shan C, Arbiser JL, Cohen C, Brat D, Miziorko HM, Kim E, Abdel-Wahab O, Merghoub T, Fröhling S, Scholl C, Tamayo P, Barbie DA, Zhou L, Pollack BP, Fisher K, Kudchadkar RR, Lawson DH, Sica G, Rossi M, Lonial S, Khoury HJ, Khuri FR, Lee BH, Boggon TJ, He C, Kang S, Chen J: Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling. Mol Cell. 2015 Aug 6; 2015 Jul 2. PMID: 26145173

Fisher OS, Deng H, Liu D, Zhang Y, Wei R, Deng Y, Zhang F, Louvi A, Turk BE, Boggon TJ, Su B: Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex. Nat Commun. 2015 Aug 3; 2015 Aug 3. PMID: 26235885

Chakraborty AK, Zerillo C, DiGiovanna MP: In vitro and in vivo studies of the combination of IGF1R inhibitor figitumumab (CP-751,871) with HER2 inhibitors trastuzumab and neratinib. Breast Cancer Res Treat. 2015 Aug; 2015 Jul 21. PMID: 26195122

Mougalian SS, Soulos PR, Killelea BK, Lannin DR, Abu-Khalaf MM, DiGiovanna MP, Sanft TB, Pusztai L, Gross CP, Chagpar AB: Use of neoadjuvant chemotherapy for patients with stage I to III breast cancer in the United States. Cancer. 2015 Aug 1; 2015 Apr 22. PMID: 25902916

Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, Kimmelman AC, Locasale JW, Lunt SY, Maddocks OD, Malloy C, Metallo CM, Meuillet EJ, Munger J, Nöh K, Rabinowitz JD, Ralser M, Sauer U, Stephanopoulos G, St-Pierre J, Tennant DA, Wittmann C, Vander Heiden MG, Vazquez A, Vousden K, Young JD, Zamboni N, Fendt SM: A roadmap for interpreting (13)C metabolite labeling patterns from cells. Curr Opin Biotechnol. 2015 Aug; 2015 Feb 28. PMID: 25731751

Ghazal S, McKinnon B, Zhou J, Mueller M, Men Y, Yang L, Mueller M, Flannery C, Huang Y, Taylor HS: H19 lncRNA alters stromal cell growth via IGF signaling in the endometrium of women with endometriosis. EMBO Mol Med. 2015 Aug. PMID: 26089099

Ardeshirpour L, Dumitru C, Dann P, Sterpka J, VanHouten J, Kim W, Kostenuik P, Wysolmerski J: OPG Treatment Prevents Bone Loss During Lactation But Does Not Affect Milk Production or Maternal Calcium Metabolism. Endocrinology. 2015 Aug; 2015 May 11. PMID: 25961842

Schwartz MA: The importance of indifference in scientific research. J Cell Sci. 2015 Aug 1; 2015 Jul 1. PMID: 26136366

Munoz-Abraham AS, Judeeba S, Alkukhun A, Alfadda T, Patron-Lozano R, Rodriguez-Davalos MI, Geibel JP: A new method to measure intestinal secretion using fluorescein isothiocyanate-inulin in small bowel of rats. J Surg Res. 2015 Aug; 2015 Apr 20. PMID: 25976849

Petrylak DP: Should the Urologist Treat Castration Resistant Prostate Cancer? No. J Urol. 2015 Aug; 2015 May 15. PMID: 25986508

Myung P, Greco V: Stem Cells Show Parental Control. Cell. 2015 Jul 30. PMID: 26232219

Price NL, Fernández-Hernando C: Novel Role of miR-33 in Regulating of Mitochondrial Function. Circ Res. 2015 Jul 17. PMID: 26185207

Egan DF, Chun MG, Vamos M, Zou H, Rong J, Miller CJ, Lou HJ, Raveendra-Panickar D, Yang CC, Sheffler DJ, Teriete P, Asara JM, Turk BE, Cosford ND, Shaw RJ: Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates. Mol Cell. 2015 Jul 16; 2015 Jun 25. PMID: 26118643

Cox CM, Mandell EK, Stewart L, Lu R, Johnson DL, McCarter SD, Tavares A, Runyan R, Ghosh S, Wilson JM: Endosomal regulation of contact inhibition through the AMOT:YAP pathway. Mol Biol Cell. 2015 Jul 15; 2015 May 20. PMID: 25995376

Bihuniak JD, Insogna KL: The effects of dietary protein and amino acids on skeletal metabolism. Mol Cell Endocrinol. 2015 Jul 15; 2015 Apr 2. PMID: 25843057

Gagliani N, Amezcua Vesely MC, Iseppon A, Brockmann L, Xu H, Palm NW, de Zoete MR, Licona-Limón P, Paiva RS, Ching T, Weaver C, Zi X, Pan X, Fan R, Garmire LX, Cotton MJ, Drier Y, Bernstein B, Geginat J, Stockinger B, Esplugues E, Huber S, Flavell RA: Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation. Nature. 2015 Jul 9; 2015 Apr 29. PMID: 25924064

Chai TC: Continence and micturition: physiological mechanisms under behavioral control. Am J Physiol Renal Physiol. 2015 Jul 1; 2015 May 13. PMID: 25972511

García R, Nistal JF, Merino D, Price NL, Fernández-Hernando C, Beaumont J, González A, Hurlé MA, Villar AV: p-SMAD2/3 and DICER promote pre-miR-21 processing during pressure overload-associated myocardial remodeling. Biochim Biophys Acta. 2015 Jul; 2015 Apr 15. PMID: 25887159

Kluger HM, Zito CR, Barr ML, Baine MK, Chiang VL, Sznol M, Rimm DL, Chen L, Jilaveanu LB: Characterization of PD-L1 Expression and Associated T-cell Infiltrates in Metastatic Melanoma Samples from Variable Anatomic Sites. Clin Cancer Res. 2015 Jul 1; 2015 Mar 18. PMID: 25788491

Weerachayaphorn J, Amaya MJ, Spirli C, Chansela P, Mitchell-Richards KA, Ananthanarayanan M, Nathanson MH: Nuclear Factor, Erythroid 2-Like 2 Regulates Expression of Type 3 Inositol 1,4,5-Trisphosphate Receptor and Calcium Signaling in Cholangiocytes. Gastroenterology. 2015 Jul; 2015 Mar 18. PMID: 25796361

Imel EA, Zhang X, Ruppe MD, Weber TJ, Klausner MA, Ito T, Vergeire M, Humphrey JS, Glorieux FH, Portale AA, Insogna K, Peacock M, Carpenter TO: Prolonged Correction of Serum Phosphorus in Adults With X-Linked Hypophosphatemia Using Monthly Doses of KRN23. J Clin Endocrinol Metab. 2015 Jul; 2015 Apr 28. PMID: 25919461

Theodosakis N, Held MA, Marzuka-Alcala A, Meeth KM, Micevic G, Long GV, Scolyer RA, Stern DF, Bosenberg MW: BRAF Inhibition Decreases Cellular Glucose Uptake in Melanoma in Association with Reduction in Cell Volume. Mol Cancer Ther. 2015 Jul; 2015 May 6. PMID: 25948295

Pineda CM, Park S, Mesa KR, Wolfel M, Gonzalez DG, Haberman AM, Rompolas P, Greco V: Intravital imaging of hair follicle regeneration in the mouse. Nat Protoc. 2015 Jul; 2015 Jun 25. PMID: 26110716

Guerra MT, Nathanson MH: Calcium signaling and secretion in cholangiocytes. Pancreatology. 2015 Jul; 2015 Jun 12. PMID: 26100660

Vucic E, Alfadda T, MacGregor GG, Dong K, Wang T, Geibel JP: Kir1.1 (ROMK) and Kv7.1 (KCNQ1/KvLQT1) are essential for normal gastric acid secretion: importance of functional Kir1.1. Pflugers Arch. 2015 Jul; 2014 Aug 17. PMID: 25127675

Langdon CG, Held MA, Platt JT, Meeth K, Iyidogan P, Mamillapalli R, Koo AB, Klein M, Liu Z, Bosenberg MW, Stern DF: The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors. Pigment Cell Melanoma Res. 2015 Jul; 2015 May 6. PMID: 25854919

Kibbey RG: SGLT-2 inhibition and glucagon: Cause for alarm? Trends Endocrinol Metab. 2015 Jul; 2015 Jun 6. PMID: 26059706

Xue Q, Lu Y, Eisele MR, Sulistijo ES, Khan N, Fan R, Miller-Jensen K: Analysis of single-cell cytokine secretion reveals a role for paracrine signaling in coordinating macrophage responses to TLR4 stimulation. Sci Signal. 2015 Jun 16; 2015 Jun 16. PMID: 26082435

Mesa KR, Rompolas P, Greco V: The Dynamic Duo: Niche/Stem Cell Interdependency. Stem Cell Reports. 2015 Jun 9; 2015 May 28. PMID: 26028534

Politi K, Ayeni D, Lynch T: The Next Wave of EGFR Tyrosine Kinase Inhibitors Enter the Clinic. Cancer Cell. 2015 Jun 8. PMID: 26058074

Mesa KR, Rompolas P, Zito G, Myung P, Sun TY, Brown S, Gonzalez DG, Blagoev KB, Haberman AM, Greco V: Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool. Nature. 2015 Jun 4; 2015 Apr 6. PMID: 25849774

Abu-Khalaf MM, Baumgart MA, Gettinger SN, Doddamane I, Tuck DP, Hou S, Chen N, Sullivan C, Lezon-Geyda K, Zelterman D, Hatzis C, Deshpande H, Digiovanna MP, Azodi M, Schwartz PE, Harris LN: Phase 1b study of the mammalian target of rapamycin inhibitor sirolimus in combination with nanoparticle albumin-bound paclitaxel in patients with advanced solid tumors. Cancer. 2015 Jun 1; 2015 Feb 3. PMID: 25649370

Blume-Jensen P, Berman DM, Rimm DL, Shipitsin M, Putzi M, Nifong TP, Small C, Choudhury S, Capela T, Coupal L, Ernst C, Hurley A, Kaprelyants A, Chang H, Giladi E, Nardone J, Dunyak J, Loda M, Klein EA, Magi-Galluzzi C, Latour M, Epstein JI, Kantoff P, Saad F: Development and clinical validation of an in situ biopsy-based multimarker assay for risk stratification in prostate cancer. Clin Cancer Res. 2015 Jun 1; 2015 Mar 2. PMID: 25733599

Li Y, Tomko RJ Jr, Hochstrasser M: Proteasomes: Isolation and Activity Assays. Curr Protoc Cell Biol. 2015 Jun 1; 2015 Jun 1. PMID: 26061243

Kerstetter JE, Bihuniak JD, Brindisi J, Sullivan RR, Mangano KM, Larocque S, Kotler BM, Simpson CA, Cusano AM, Gaffney-Stomberg E, Kleppinger A, Reynolds J, Dziura J, Kenny AM, Insogna KL: The Effect of a Whey Protein Supplement on Bone Mass in Older Caucasian Adults. J Clin Endocrinol Metab. 2015 Jun; 2015 Apr 6. PMID: 25844619

Osman KT, Lou HJ, Qiu W, Brand V, Edwards AM, Turk BE, Hui R: Biochemical characterization of FIKK8--A unique protein kinase from the malaria parasite Plasmodium falciparum and other apicomplexans. Mol Biochem Parasitol. 2015 Jun; 2015 Jun 22. PMID: 26112892

Han C, Yang Y, de Greef BT, Hoeijmakers JG, Gerrits MM, Verhamme C, Qu J, Lauria G, Merkies IS, Faber CG, Dib-Hajj SD, Waxman SG: The Domain II S4-S5 Linker in Nav1.9: A Missense Mutation Enhances Activation, Impairs Fast Inactivation, and Produces Human Painful Neuropathy. Neuromolecular Med. 2015 Jun; 2015 Mar 20. PMID: 25791876

Rotllan N, Wanschel AC, Fernández-Hernando A, Salerno AG, Offermanns S, Sessa WC, Fernández-Hernando C: Genetic Evidence Supports a Major Role for Akt1 in VSMCs During Atherogenesis. Circ Res. 2015 May 22; 2015 Apr 13. PMID: 25868464

Ha BH, Morse EM, Turk BE, Boggon TJ: Signaling, Regulation, and Specificity of the Type II p21-activated Kinases. J Biol Chem. 2015 May 22; 2015 Apr 8. PMID: 25855792

Carvajal-Hausdorf DE, Schalper KA, Pusztai L, Psyrri A, Kalogeras KT, Kotoula V, Fountzilas G, Rimm DL: Measurement of Domain-Specific HER2 (ERBB2) Expression May Classify Benefit From Trastuzumab in Breast Cancer. J Natl Cancer Inst. 2015 Aug; 2015 May 19. PMID: 25991002

Politi K, Herbst RS: Lung cancer in the era of precision medicine. Clin Cancer Res. 2015 May 15. PMID: 25979927

Stewart RM, Zubek AE, Rosowski KA, Schreiner SM, Horsley V, King MC: Nuclear-cytoskeletal linkages facilitate cross talk between the nucleus and intercellular adhesions. J Cell Biol. 2015 May 11. PMID: 25963820

Jilaveanu LB, Parisi F, Barr ML, Zito CR, Cruz-Munoz W, Kerbel RS, Rimm DL, Bosenberg MW, Halaban R, Kluger Y, Kluger HM: PLEKHA5 as a Biomarker and Potential Mediator of Melanoma Brain Metastasis. Clin Cancer Res. 2015 May 1; 2014 Oct 14. PMID: 25316811

Kim JW, Tomita Y, Trepel J, Apolo AB: Emerging immunotherapies for bladder cancer. Curr Opin Oncol. 2015 May. PMID: 25811346

Morgensztern D, Politi K, Herbst RS: EGFR Mutations in Non-Small-Cell Lung Cancer: Find, Divide, and Conquer. JAMA Oncol. 2015 May. PMID: 26181013

Perry RJ, Lee S, Ma L, Zhang D, Schlessinger J, Shulman GI: FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic-pituitary-adrenal axis. Nat Commun. 2015 Apr 28; 2015 Apr 28. PMID: 25916467

McNeer NA, Anandalingam K, Fields RJ, Caputo C, Kopic S, Gupta A, Quijano E, Polikoff L, Kong Y, Bahal R, Geibel JP, Glazer PM, Saltzman WM, Egan ME: Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium. Nat Commun. 2015 Apr 27; 2015 Apr 27. PMID: 25914116

Wang L, Velazquez H, Chang J, Safirstein R, Desir GV: Identification of a receptor for extracellular renalase. PLoS One. 2015; 2015 Apr 23. PMID: 25906147

Kunstman JW, Juhlin CC, Goh G, Brown TC, Stenman A, Healy JM, Rubinstein JC, Choi M, Kiss N, Nelson-Williams C, Mane S, Rimm DL, Prasad ML, Höög A, Zedenius J, Larsson C, Korah R, Lifton RP, Carling T: Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing. Hum Mol Genet. 2015 Apr 15; 2015 Jan 9. PMID: 25576899

Lu R, Dalgalan D, Mandell EK, Parker SS, Ghosh S, Wilson JM: PKCι interacts with Rab14 and modulates epithelial barrier function through regulation of claudin-2 levels. Mol Biol Cell. 2015 Apr 15; 2015 Feb 18. PMID: 25694446

Nygaard HB, Wagner AF, Bowen GS, Good SP, MacAvoy MG, Strittmatter KA, Kaufman AC, Rosenberg BJ, Sekine-Konno T, Varma P, Chen K, Koleske AJ, Reiman EM, Strittmatter SM, van Dyck CH: A phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimer's disease. Alzheimers Res Ther. 2015; 2015 Apr 14. PMID: 25874001

Humphrey JD, Schwartz MA, Tellides G, Milewicz DM: Role of mechanotransduction in vascular biology: focus on thoracic aortic aneurysms and dissections. Circ Res. 2015 Apr 10. PMID: 25858068

Lin B, Levchenko A: Spatial manipulation with microfluidics. Front Bioeng Biotechnol. 2015; 2015 Apr 8. PMID: 25905100

Lin B, Yin T, Wu YI, Inoue T, Levchenko A: Interplay between chemotaxis and contact inhibition of locomotion determines exploratory cell migration. Nat Commun. 2015 Apr 8; 2015 Apr 8. PMID: 25851023

Tadeu AM, Lin S, Hou L, Chung L, Zhong M, Zhao H, Horsley V: Transcriptional profiling of ectoderm specification to keratinocyte fate in human embryonic stem cells. PLoS One. 2015; 2015 Apr 7. PMID: 25849374

Ha BH, Simpson MA, Koleske AJ, Boggon TJ: Structure of the ABL2/ARG kinase in complex with dasatinib. Acta Crystallogr F Struct Biol Commun. 2015 Apr; 2015 Mar 20. PMID: 25849507

Han CS, Herrin MA, Pitruzzello MC, Mulla MJ, Werner EF, Pettker CM, Flannery CA, Abrahams VM: Glucose and metformin modulate human first trimester trophoblast function: a model and potential therapy for diabetes-associated uteroplacental insufficiency. Am J Reprod Immunol. 2015 Apr; 2014 Nov 14. PMID: 25394884

Bantikassegn A, Song X, Politi K: Isolation of epithelial, endothelial, and immune cells from lungs of transgenic mice with oncogene-induced lung adenocarcinomas. Am J Respir Cell Mol Biol. 2015 Apr. PMID: 25347711

Callender GG, Kaplan BJ, White RL, Brenin DR, Chagpar AB, Dalal KM, Howard-McNatt M, Howe J, Kim J, Kurtzman SH, Mansour JC, Mittendorf EA, Stewart JH 4th, Temple LK, Stella P, Cummings C, Wong SL, Klimberg VS: Maintenance of certification: what everyone needs to know. Ann Surg Oncol. 2015 Apr; 2015 Feb 7. PMID: 25663592

Goodwin JE, Zhang X, Rotllan N, Feng Y, Zhou H, Fernández-Hernando C, Yu J, Sessa WC: Endothelial glucocorticoid receptor suppresses atherogenesis--brief report. Arterioscler Thromb Vasc Biol. 2015 Apr; 2015 Feb 19. PMID: 25810297

Wimberly H, Brown JR, Schalper K, Haack H, Silver MR, Nixon C, Bossuyt V, Pusztai L, Lannin DR, Rimm DL: PD-L1 Expression Correlates with Tumor-Infiltrating Lymphocytes and Response to Neoadjuvant Chemotherapy in Breast Cancer. Cancer Immunol Res. 2015 Apr; 2014 Dec 19. PMID: 25527356

Scortegagna M, Lau E, Zhang T, Feng Y, Sereduk C, Yin H, De SK, Meeth K, Platt JT, Langdon CG, Halaban R, Pellecchia M, Davies MA, Brown K, Stern DF, Bosenberg M, Ronai ZA: PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets. Cancer Res. 2015 Apr 1; 2015 Feb 24. PMID: 25712345

Zheng S, Long L, Li Y, Xu Y, Jiqin Z, Ji W, Min W: A Novel ASK Inhibitor AGI-1067 Inhibits TLR-4-Mediated Activation of ASK1 by Preventing Dissociation of Thioredoxin from ASK1. Cardiovasc Pharm Open Access. 2015 Apr; 2015 Feb 26. PMID: 28435845

Nathanson MH: What is Hepatology looking for? Hepatology. 2015 Apr; 2015 Mar 10. PMID: 25581014

Petrylak DP, Gandhi JG, Clark WR, Heath E, Lin J, Oh WK, Agus DB, Carthon B, Moran S, Kong N, Suri A, Bargfrede M, Liu G: Phase 1/2 study of orteronel (TAK-700), an investigational 17,20-lyase inhibitor, with docetaxel-prednisone in metastatic castration-resistant prostate cancer. Invest New Drugs. 2015 Apr; 2015 Jan 4. PMID: 25556680

Bindesbøll C, Fan Q, Nørgaard RC, MacPherson L, Ruan HB, Wu J, Pedersen TÅ, Steffensen KR, Yang X, Matthews J, Mandrup S, Nebb HI, Grønning-Wang LM: Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity. J Lipid Res. 2015 Apr; 2015 Feb 27. PMID: 25724563

Simpson CA, Cusano AM, Bihuniak J, Walker J, Insogna KL: Effect of 25(OH) vitamin D reference method procedure (RMP) alignment on clinical measurements obtained with the IDS-iSYS chemiluminescent-based automated analyzer. J Steroid Biochem Mol Biol. 2015 Apr; 2014 Sep 18. PMID: 25239596

Carvajal-Hausdorf DE, Schalper KA, Neumeister VM, Rimm DL: Quantitative measurement of cancer tissue biomarkers in the lab and in the clinic. Lab Invest. 2015 Apr; 2014 Dec 15. PMID: 25502176

Petrylak DP, Vogelzang NJ, Budnik N, Wiechno PJ, Sternberg CN, Doner K, Bellmunt J, Burke JM, de Olza MO, Choudhury A, Gschwend JE, Kopyltsov E, Flechon A, Van As N, Houede N, Barton D, Fandi A, Jungnelius U, Li S, de Wit R, Fizazi K: Docetaxel and prednisone with or without lenalidomide in chemotherapy-naive patients with metastatic castration-resistant prostate cancer (MAINSAIL): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet Oncol. 2015 Apr; 2015 Mar 3. PMID: 25743937

Colangelo CM, Ivosev G, Chung L, Abbott T, Shifman M, Sakaue F, Cox D, Kitchen RR, Burton L, Tate SA, Gulcicek E, Bonner R, Rinehart J, Nairn AC, Williams KR: Development of a highly automated and multiplexed targeted proteome pipeline and assay for 112 rat brain synaptic proteins. Proteomics. 2015 Apr; 2015 Feb 12. PMID: 25476245

Draheim KM, Li X, Zhang R, Fisher OS, Villari G, Boggon TJ, Calderwood DA: CCM2-CCM3 interaction stabilizes their protein expression and permits endothelial network formation. J Cell Biol. 2015 Mar 30. PMID: 25825518

Coon BG, Baeyens N, Han J, Budatha M, Ross TD, Fang JS, Yun S, Thomas JL, Schwartz MA: Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. J Cell Biol. 2015 Mar 30; 2015 Mar 23. PMID: 25800053

Simpson MA, Bradley WD, Harburger D, Parsons M, Calderwood DA, Koleske AJ: Direct interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase. J Biol Chem. 2015 Mar 27; 2015 Feb 18. PMID: 25694433

Huang Q, Zhou HJ, Zhang H, Huang Y, Hinojosa-Kirschenbaum F, Fan P, Yao L, Belardinelli L, Tellides G, Giordano FJ, Budas GR, Min W: Thioredoxin-2 inhibits mitochondrial reactive oxygen species generation and apoptosis stress kinase-1 activity to maintain cardiac function. Circulation. 2015 Mar 24; 2015 Jan 27. PMID: 25628390

Davidson NE, Rimm DL: Expertise vs evidence in assessment of breast biopsies: an atypical science. JAMA. 2015 Mar 17. PMID: 25781438

Tornavaca O, Chia M, Dufton N, Almagro LO, Conway DE, Randi AM, Schwartz MA, Matter K, Balda MS: ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation. J Cell Biol. 2015 Mar 16; 2015 Mar 9. PMID: 25753039

Song X, Fan PD, Bantikassegn A, Guha U, Threadgill DW, Varmus H, Politi K: ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas. Cancer Res. 2015 Mar 15; 2015 Jan 16. PMID: 25596284

Perry RJ, Zhang D, Zhang XM, Boyer JL, Shulman GI: Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats. Science. 2015 Mar 13; 2015 Feb 26. PMID: 25721504

Jeon YJ, Khelifa S, Ratnikov B, Scott DA, Feng Y, Parisi F, Ruller C, Lau E, Kim H, Brill LM, Jiang T, Rimm DL, Cardiff RD, Mills GB, Smith JW, Osterman AL, Kluger Y, Ronai ZA: Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies. Cancer Cell. 2015 Mar 9. PMID: 25759021

Chakraborty AK, Mehra R, Digiovanna MP: Co-targeting ER and HER family receptors induces apoptosis in HER2-normal or overexpressing breast cancer models. Anticancer Res. 2015 Mar. PMID: 25750271

Kleppe M, Kwak M, Koppikar P, Riester M, Keller M, Bastian L, Hricik T, Bhagwat N, McKenney AS, Papalexi E, Abdel-Wahab O, Rampal R, Marubayashi S, Chen JJ, Romanet V, Fridman JS, Bromberg J, Teruya-Feldstein J, Murakami M, Radimerski T, Michor F, Fan R, Levine RL: JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response. Cancer Discov. 2015 Mar; 2015 Jan 8. PMID: 25572172

Shenkar R, Shi C, Rebeiz T, Stockton RA, McDonald DA, Mikati AG, Zhang L, Austin C, Akers AL, Gallione CJ, Rorrer A, Gunel M, Min W, De Souza JM, Lee C, Marchuk DA, Awad IA: Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations. Genet Med. 2015 Mar; 2014 Aug 14. PMID: 25122144

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Fizazi K, Jones R, Oudard S, Efstathiou E, Saad F, de Wit R, De Bono J, Cruz FM, Fountzilas G, Ulys A, Carcano F, Agarwal N, Agus D, Bellmunt J, Petrylak DP, Lee SY, Webb IJ, Tejura B, Borgstein N, Dreicer R: Phase III, randomized, double-blind, multicenter trial comparing orteronel (TAK-700) plus prednisone with placebo plus prednisone in patients with metastatic castration-resistant prostate cancer that has progressed during or after docetaxel-based therapy: ELM-PC 5. J Clin Oncol. 2015 Mar 1; 2015 Jan 26. PMID: 25624429

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Powles T, Eder JP, Fine GD, Braiteh FS, Loriot Y, Cruz C, Bellmunt J, Burris HA, Petrylak DP, Teng SL, Shen X, Boyd Z, Hegde PS, Chen DS, Vogelzang NJ: MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. Nature. 2014 Nov 27. PMID: 25428503

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Huang J, Yang Y, Dib-Hajj SD, van Es M, Zhao P, Salomon J, Drenth JP, Waxman SG: Depolarized inactivation overcomes impaired activation to produce DRG neuron hyperexcitability in a Nav1.7 mutation in a patient with distal limb pain. J Neurosci. 2014 Sep 10. PMID: 25209274

Stiegler AL, Zhang R, Liu W, Boggon TJ: Structural determinants for binding of sorting nexin 17 (SNX17) to the cytoplasmic adaptor protein Krev interaction trapped 1 (KRIT1). J Biol Chem. 2014 Sep 5; 2014 Jul 24. PMID: 25059659

Bhatnagar S, Zhu X, Ou J, Lin L, Chamberlain L, Zhu LJ, Wajapeyee N, Green MR: Genetic and pharmacological reactivation of the mammalian inactive X chromosome. Proc Natl Acad Sci U S A. 2014 Sep 2; 2014 Aug 18. PMID: 25136103

Guo X, Wang L, Velazquez H, Safirstein R, Desir GV: Renalase: its role as a cytokine, and an update on its association with type 1 diabetes and ischemic stroke. Curr Opin Nephrol Hypertens. 2014 Sep. PMID: 24992568

Goedeke L, Salerno A, Ramírez CM, Guo L, Allen RM, Yin X, Langley SR, Esau C, Wanschel A, Fisher EA, Suárez Y, Baldán A, Mayr M, Fernández-Hernando C: Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice. EMBO Mol Med. 2014 Sep. PMID: 25038053

Carpenter TO, Olear EA, Zhang JH, Ellis BK, Simpson CA, Cheng D, Gundberg CM, Insogna KL: Effect of paricalcitol on circulating parathyroid hormone in X-linked hypophosphatemia: a randomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab. 2014 Sep; 2014 Jul 16. PMID: 25029424

Hu MI, Glezerman IG, Leboulleux S, Insogna K, Gucalp R, Misiorowski W, Yu B, Zorsky P, Tosi D, Bessudo A, Jaccard A, Tonini G, Ying W, Braun A, Jain RK: Denosumab for treatment of hypercalcemia of malignancy. J Clin Endocrinol Metab. 2014 Sep; 2014 Jun 10. PMID: 24915117

Fenn KM, Evans SB, McCorkle R, DiGiovanna MP, Pusztai L, Sanft T, Hofstatter EW, Killelea BK, Knobf MT, Lannin DR, Abu-Khalaf M, Horowitz NR, Chagpar AB: Impact of financial burden of cancer on survivors' quality of life. J Oncol Pract. 2014 Sep; 2014 May 27. PMID: 24865220

Shan C, Elf S, Ji Q, Kang HB, Zhou L, Hitosugi T, Jin L, Lin R, Zhang L, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J: Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth. Mol Cell. 2014 Aug 21; 2014 Jul 17. PMID: 25042803

Kim JD, Toda C, D'Agostino G, Zeiss CJ, DiLeone RJ, Elsworth JD, Kibbey RG, Chan O, Harvey BK, Richie CT, Savolainen M, Myöhänen T, Jeong JK, Diano S: Hypothalamic prolyl endopeptidase (PREP) regulates pancreatic insulin and glucagon secretion in mice. Proc Natl Acad Sci U S A. 2014 Aug 12; 2014 Jul 28. PMID: 25071172

Kusne Y, Carrera-Silva EA, Perry AS, Rushing EJ, Mandell EK, Dietrich JD, Errasti AE, Gibbs D, Berens ME, Loftus JC, Hulme C, Yang W, Lu Z, Aldape K, Sanai N, Rothlin CV, Ghosh S: Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma. Sci Signal. 2014 Aug 12; 2014 Aug 12. PMID: 25118327

Goodwin JM, Svensson RU, Lou HJ, Winslow MM, Turk BE, Shaw RJ: An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential. Mol Cell. 2014 Aug 7; 2014 Jul 17. PMID: 25042806

Xu J, Chatterjee M, Baguley TD, Brouillette J, Kurup P, Ghosh D, Kanyo J, Zhang Y, Seyb K, Ononenyi C, Foscue E, Anderson GM, Gresack J, Cuny GD, Glicksman MA, Greengard P, Lam TT, Tautz L, Nairn AC, Ellman JA, Lombroso PJ: Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease. PLoS Biol. 2014 Aug; 2014 Aug 5. PMID: 25093460

Leerberg JM, Gomez GA, Verma S, Moussa EJ, Wu SK, Priya R, Hoffman BD, Grashoff C, Schwartz MA, Yap AS: Tension-sensitive actin assembly supports contractility at the epithelial zonula adherens. Curr Biol. 2014 Aug 4; 2014 Jul 24. PMID: 25065757

Alfadda TI, Saleh AM, Houillier P, Geibel JP: Calcium-sensing receptor 20 years later. Am J Physiol Cell Physiol. 2014 Aug 1; 2014 May 28. PMID: 24871857

Wimberly H, Han G, Pinnaduwage D, Murphy LC, Yang XR, Andrulis IL, Sherman M, Figueroa J, Rimm DL: ERβ splice variant expression in four large cohorts of human breast cancer patient tumors. Breast Cancer Res Treat. 2014 Aug; 2014 Jul 10. PMID: 25007965

Hatzis C, Bedard PL, Birkbak NJ, Beck AH, Aerts HJ, Stem DF, Shi L, Clarke R, Quackenbush J, Haibe-Kains B: Enhancing reproducibility in cancer drug screening: how do we move forward? Cancer Res. 2014 Aug 1; 2014 Jul 11. PMID: 25015668

Canfrán-Duque A, Ramírez CM, Goedeke L, Lin CS, Fernández-Hernando C: microRNAs and HDL life cycle. Cardiovasc Res. 2014 Aug 1; 2014 Jun 3. PMID: 24895349

Levchenko A, Nemenman I: Cellular noise and information transmission. Curr Opin Biotechnol. 2014 Aug; 2014 Jun 9. PMID: 24922112

Goedeke L, Aranda JF, Fernández-Hernando C: microRNA regulation of lipoprotein metabolism. Curr Opin Lipidol. 2014 Aug. PMID: 24978143

How J, Brown JR, Saylor S, Rimm DL: Macrophage expression of tartrate-resistant acid phosphatase as a prognostic indicator in colon cancer. Histochem Cell Biol. 2014 Aug; 2014 Jan 16. PMID: 24429833

Rothlin CV, Leighton JA, Ghosh S: Tyro3, Axl, and Mertk receptor signaling in inflammatory bowel disease and colitis-associated cancer. Inflamm Bowel Dis. 2014 Aug. PMID: 24846720

Shan C, Kang HB, Elf S, Xie J, Gu TL, Aguiar M, Lonning S, Hitosugi T, Chung TW, Arellano M, Khoury HJ, Shin DM, Khuri FR, Boggon TJ, Fan J: Tyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth. J Biol Chem. 2014 Aug 1; 2014 Jun 24. PMID: 24962578

Kong Y, Krauthammer M, Halaban R: Rare SF3B1 R625 mutations in cutaneous melanoma. Melanoma Res. 2014 Aug. PMID: 24709888

Wali VB, Haskins JW, Gilmore-Hebert M, Platt JT, Liu Z, Stern DF: Convergent and divergent cellular responses by ErbB4 isoforms in mammary epithelial cells. Mol Cancer Res. 2014 Aug; 2014 May 14. PMID: 24829397

Paardekooper Overman J, Yi JS, Bonetti M, Soulsby M, Preisinger C, Stokes MP, Hui L, Silva JC, Overvoorde J, Giansanti P, Heck AJ, Kontaridis MI, den Hertog J, Bennett AM: PZR coordinates Shp2 Noonan and LEOPARD syndrome signaling in zebrafish and mice. Mol Cell Biol. 2014 Aug; 2014 May 27. PMID: 24865967

Gupta R, Dong Y, Solomon PD, Wettersten HI, Cheng CJ, Min JN, Henson J, Dogra SK, Hwang SH, Hammock BD, Zhu LJ, Reddel RR, Saltzman WM, Weiss RH, Chang S, Green MR, Wajapeyee N: Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A. Proc Natl Acad Sci U S A. 2014 Jul 29; 2014 Jul 14. PMID: 25024194

Ji W, Yang M, Praggastis A, Li Y, Zhou HJ, He Y, Ghazvinian R, Cincotta DJ, Rice KP, Min W: Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death. PLoS One. 2014; 2014 Jul 28. PMID: 25068797

Lu Y, Wajapeyee N, Turker MS, Glazer PM: Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1. Cell Rep. 2014 Jul 24; 2014 Jul 17. PMID: 25043185

Galan JA, Geraghty KM, Lavoie G, Kanshin E, Tcherkezian J, Calabrese V, Jeschke GR, Turk BE, Ballif BA, Blenis J, Thibault P, Roux PP: Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3. Proc Natl Acad Sci U S A. 2014 Jul 22; 2014 Jul 7. PMID: 25002506

Sun P, Watanabe K, Fallahi M, Lee B, Afetian ME, Rheaume C, Wu D, Horsley V, Dai X: Pygo2 regulates β-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasia. Proc Natl Acad Sci U S A. 2014 Jul 15; 2014 Jun 30. PMID: 24982158

Shipitsin M, Small C, Giladi E, Siddiqui S, Choudhury S, Hussain S, Huang YE, Chang H, Rimm DL, Berman DM, Nifong TP, Blume-Jensen P: Automated quantitative multiplex immunofluorescence in situ imaging identifies phospho-S6 and phospho-PRAS40 as predictive protein biomarkers for prostate cancer lethality. Proteome Sci. 2014; 2014 Jul 12. PMID: 25075204

Gifford SM, Liu W, Mader CC, Halo TL, Machida K, Boggon TJ, Koleske AJ: Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin. J Biol Chem. 2014 Jul 11; 2014 Jun 2. PMID: 24891505

Jeffery E, Berry R, Church CD, Yu S, Shook BA, Horsley V, Rosen ED, Rodeheffer MS: Characterization of Cre recombinase models for the study of adipose tissue. Adipocyte. 2014 Jul 1; 2014 Jun 27. PMID: 25068087

Wadia R, Petrylak DP: New developments in the treatment of castration resistant prostate cancer. Asian J Androl. 2014 Jul-Aug. PMID: 24759588

Perry RJ, Zhang XM, Zhang D, Kumashiro N, Camporez JP, Cline GW, Rothman DL, Shulman GI: Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis. Nat Med. 2014 Jul; 2014 Jun 15. PMID: 24929951

Apolo AB, Kim JW, Bochner BH, Steinberg SM, Bajorin DF, Kelly WK, Agarwal PK, Koppie TM, Kaag MG, Quinn DI, Vogelzang NJ, Sridhar SS: Examining the management of muscle-invasive bladder cancer by medical oncologists in the United States. Urol Oncol. 2014 Jul; 2014 May 16. PMID: 24840869

Lee Y, Dominy JE, Choi YJ, Jurczak M, Tolliday N, Camporez JP, Chim H, Lim JH, Ruan HB, Yang X, Vazquez F, Sicinski P, Shulman GI, Puigserver P: Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression. Nature. 2014 Jun 26; 2014 May 25. PMID: 24870244

Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald MJ, Jurczak MJ, Camporez JP, Lee HY, Cline GW, Samuel VT, Kibbey RG, Shulman GI: Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase. Nature. 2014 Jun 26; 2014 May 21. PMID: 24847880

Vassilakopoulou M, Togun T, Dafni U, Cheng H, Bordeaux J, Neumeister VM, Bobos M, Pentheroudakis G, Skarlos DV, Pectasides D, Kotoula V, Fountzilas G, Rimm DL, Psyrri A: In situ quantitative measurement of HER2mRNA predicts benefit from trastuzumab-containing chemotherapy in a cohort of metastatic breast cancer patients. PLoS One. 2014; 2014 Jun 26. PMID: 24968015

Kwak M, Kim DJ, Lee MR, Wu Y, Han L, Lee SK, Fan R: Nanowire array chips for molecular typing of rare trafficking leukocytes with application to neurodegenerative pathology. Nanoscale. 2014 Jun 21. PMID: 24705924

Wilson MA, Zhao F, Letrero R, D'Andrea K, Rimm DL, Kirkwood JM, Kluger HM, Lee SJ, Schuchter LM, Flaherty KT, Nathanson KL: Correlation of somatic mutations and clinical outcome in melanoma patients treated with Carboplatin, Paclitaxel, and sorafenib. Clin Cancer Res. 2014 Jun 15; 2014 Apr 8. PMID: 24714776

Perry RJ, Samuel VT, Petersen KF, Shulman GI: The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes. Nature. 2014 Jun 5. PMID: 24899308

Fernández-Hernando C: Antiatherogenic properties of high-density lipoprotein-enriched microRNAs. Arterioscler Thromb Vasc Biol. 2014 Jun; 2014 Apr 24. PMID: 24764456

Amaya MJ, Nathanson MH: Calcium signaling and the secretory activity of bile duct epithelia. Cell Calcium. 2014 Jun; 2014 Feb 12. PMID: 24612866

Psyrri A, Lee JW, Pectasides E, Vassilakopoulou M, Kosmidis EK, Burtness BA, Rimm DL, Wanebo HJ, Forastiere AA: Prognostic biomarkers in phase II trial of cetuximab-containing induction and chemoradiation in resectable HNSCC: Eastern cooperative oncology group E2303. Clin Cancer Res. 2014 Jun 1; 2014 Apr 3. PMID: 24700741

Wang L, Velazquez H, Moeckel G, Chang J, Ham A, Lee HT, Safirstein R, Desir GV: Renalase prevents AKI independent of amine oxidase activity. J Am Soc Nephrol. 2014 Jun; 2014 Feb 7. PMID: 24511138

Moissoglu K, Kiessling V, Wan C, Hoffman BD, Norambuena A, Tamm LK, Schwartz MA: Regulation of Rac1 translocation and activation by membrane domains and their boundaries. J Cell Sci. 2014 Jun 1; 2014 Apr 2. PMID: 24695858

Ramírez CM, Lin CS, Abdelmohsen K, Goedeke L, Yoon JH, Madrigal-Matute J, Martin-Ventura JL, Vo DT, Uren PJ, Penalva LO, Gorospe M, Fernández-Hernando C: RNA binding protein HuR regulates the expression of ABCA1. J Lipid Res. 2014 Jun; 2014 Apr 11. PMID: 24729624

Barkil-Oteo A, Stern DA, Arbuckle MR: Addressing the cost of health care from the front lines of psychiatry. JAMA Psychiatry. 2014 Jun. PMID: 24696129

Nagarajan A, Dogra SK, Liu AY, Green MR, Wajapeyee N: PEA15 regulates the DNA damage-induced cell cycle checkpoint and oncogene-directed transformation. Mol Cell Biol. 2014 Jun; 2014 Apr 7. PMID: 24710276

Schwartz M: Sticking to it: tracking the paths of integrin signalling. Nat Cell Biol. 2014 Jun. PMID: 24875734

Pirazzoli V, Nebhan C, Song X, Wurtz A, Walther Z, Cai G, Zhao Z, Jia P, de Stanchina E, Shapiro EM, Gale M, Yin R, Horn L, Carbone DP, Stephens PJ, Miller V, Gettinger S, Pao W, Politi K: Acquired resistance of EGFR-mutant lung adenocarcinomas to afatinib plus cetuximab is associated with activation of mTORC1. Cell Rep. 2014 May 22; 2014 May 9. PMID: 24813888

Schalper KA, Velcheti V, Carvajal D, Wimberly H, Brown J, Pusztai L, Rimm DL: In situ tumor PD-L1 mRNA expression is associated with increased TILs and better outcome in breast carcinomas. Clin Cancer Res. 2014 May 15; 2014 Mar 19. PMID: 24647569

Etheridge RD, Alaganan A, Tang K, Lou HJ, Turk BE, Sibley LD: The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice. Cell Host Microbe. 2014 May 14. PMID: 24832449

Cheng H, Bai Y, Sikov W, Sinclair N, Bossuyt V, Abu-Khalaf MM, Harris LN, Rimm DL: Quantitative measurements of HER2 and phospho-HER2 expression: correlation with pathologic response to neoadjuvant chemotherapy and trastuzumab. BMC Cancer. 2014 May 8; 2014 May 8. PMID: 24885187

Humphrey JD, Milewicz DM, Tellides G, Schwartz MA: Cell biology. Dysfunctional mechanosensing in aneurysms. Science. 2014 May 2. PMID: 24786066

Viray H, Coulter M, Li K, Lane K, Madan A, Mitchell K, Schalper K, Hoyt C, Rimm DL: Automated objective determination of percentage of malignant nuclei for mutation testing. Appl Immunohistochem Mol Morphol. 2014 May-Jun. PMID: 24162261

de Bruin EC, Cowell C, Warne PH, Jiang M, Saunders RE, Melnick MA, Gettinger S, Walther Z, Wurtz A, Heynen GJ, Heideman DA, Gómez-Román J, García-Castaño A, Gong Y, Ladanyi M, Varmus H, Bernards R, Smit EF, Politi K, Downward J: Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer. Cancer Discov. 2014 May; 2014 Feb 17. PMID: 24535670

Moissoglu K, Schwartz MA: Spatial and temporal control of Rho GTPase functions. Cell Logist. 2014 Apr-Jun; 2014 May 1. PMID: 25610718

Fisher OS, Boggon TJ: Signaling pathways and the cerebral cavernous malformations proteins: lessons from structural biology. Cell Mol Life Sci. 2014 May; 2013 Nov 29. PMID: 24287896

Li Q, Wijesekera O, Salas SJ, Wang JY, Zhu M, Aprhys C, Chaichana KL, Chesler DA, Zhang H, Smith CL, Guerrero-Cazares H, Levchenko A, Quinones-Hinojosa A: Mesenchymal stem cells from human fat engineered to secrete BMP4 are nononcogenic, suppress brain cancer, and prolong survival. Clin Cancer Res. 2014 May 1. PMID: 24789034

Aryal B, Rotllan N, Fernández-Hernando C: Noncoding RNAs and atherosclerosis. Curr Atheroscler Rep. 2014 May. PMID: 24623179

Goldstein J, Fletcher S, Roth E, Wu C, Chun A, Horsley V: Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation. Genes Dev. 2014 May 1; 2014 Apr 14. PMID: 24732379

Ma XM, Miller MB, Vishwanatha KS, Gross MJ, Wang Y, Abbott T, Lam TT, Mains RE, Eipper BA: Nonenzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl. Mol Biol Cell. 2014 May; 2014 Mar 5. PMID: 24600045

Boras-Granic K, Dann P, Vanhouten J, Karaplis A, Wysolmerski J: Deletion of the nuclear localization sequences and C-terminus of PTHrP impairs embryonic mammary development but also inhibits PTHrP production. PLoS One. 2014; 2014 May 1. PMID: 24785493

Lee SK, Kim DJ, Lee G, Kim GS, Kwak M, Fan R: Specific rare cell capture using micro-patterned silicon nanowire platform. Biosens Bioelectron. 2014 Apr 15; 2013 Nov 8. PMID: 24274988

Chen PY, Qin L, Zhuang ZW, Tellides G, Lax I, Schlessinger J, Simons M: The docking protein FRS2α is a critical regulator of VEGF receptors signaling. Proc Natl Acad Sci U S A. 2014 Apr 15; 2014 Apr 2. PMID: 24706887

Pectasides E, Rampias T, Sasaki C, Perisanidis C, Kouloulias V, Burtness B, Zaramboukas T, Rimm D, Fountzilas G, Psyrri A: Markers of epithelial to mesenchymal transition in association with survival in head and neck squamous cell carcinoma (HNSCC). PLoS One. 2014; 2014 Apr 10. PMID: 24722213

Stark R, Kibbey RG: The mitochondrial isoform of phosphoenolpyruvate carboxykinase (PEPCK-M) and glucose homeostasis: has it been overlooked? Biochim Biophys Acta. 2014 Apr; 2013 Oct 28. PMID: 24177027

Petrylak DP: Practical guide to the use of chemotherapy in castration resistant prostate cancer. Can J Urol. 2014 Apr. PMID: 24775728

de Bono JS, Piulats JM, Pandha HS, Petrylak DP, Saad F, Aparicio LM, Sandhu SK, Fong P, Gillessen S, Hudes GR, Wang T, Scranton J, Pollak MN: Phase II randomized study of figitumumab plus docetaxel and docetaxel alone with crossover for metastatic castration-resistant prostate cancer. Clin Cancer Res. 2014 Apr 1; 2014 Feb 17. PMID: 24536060

Agarwal N, Bellmunt J, Maughan BL, Boucher KM, Choueiri TK, Qu AQ, Vogelzang NJ, Fougeray R, Niegisch G, Albers P, Wong YN, Ko YJ, Sridhar SS, Tantravahi SK, Galsky MD, Petrylak DP, Vaishampayan UN, Mehta AN, Beer TM, Sternberg CN, Rosenberg JE, Sonpavde G: Six-month progression-free survival as the primary endpoint to evaluate the activity of new agents as second-line therapy for advanced urothelial carcinoma. Clin Genitourin Cancer. 2014 Apr; 2013 Sep 28. PMID: 24220220

Lee MY, Skoura A, Park EJ, Landskroner-Eiger S, Jozsef L, Luciano AK, Murata T, Pasula S, Dong Y, Bouaouina M, Calderwood DA, Ferguson SM, De Camilli P, Sessa WC: Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis. Development. 2014 Apr; 2014 Mar 5. PMID: 24598168

Lee GS, Simpson C, Sun BH, Yao C, Foer D, Sullivan B, Matthes S, Alenina N, Belsky J, Bader M, Insogna KL: Measurement of plasma, serum, and platelet serotonin in individuals with high bone mass and mutations in LRP5. J Bone Miner Res. 2014 Apr. PMID: 24038240

Neumeister VM, Parisi F, England AM, Siddiqui S, Anagnostou V, Zarrella E, Vassilakopolou M, Bai Y, Saylor S, Sapino A, Kluger Y, Hicks DG, Bussolati G, Kwei S, Rimm DL: A tissue quality index: an intrinsic control for measurement of effects of preanalytical variables on FFPE tissue. Lab Invest. 2014 Apr; 2014 Feb 17. PMID: 24535259

Rimm DL: Next-gen immunohistochemistry. Nat Methods. 2014 Apr. PMID: 24681723

Carlyle BC, Nairn AC, Wang M, Yang Y, Jin LE, Simen AA, Ramos BP, Bordner KA, Craft GE, Davies P, Pletikos M, Šestan N, Arnsten AF, Paspalas CD: cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex. Proc Natl Acad Sci U S A. 2014 Apr 1; 2014 Mar 18. PMID: 24707050

Zito G, Saotome I, Liu Z, Ferro EG, Sun TY, Nguyen DX, Bilguvar K, Ko CJ, Greco V: Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk. Nat Commun. 2014 Mar 26; 2014 Mar 26. PMID: 24667544

Deschene ER, Myung P, Rompolas P, Zito G, Sun TY, Taketo MM, Saotome I, Greco V: β-Catenin activation regulates tissue growth non-cell autonomously in the hair stem cell niche. Science. 2014 Mar 21. PMID: 24653033

Fan HC, Fernández-Hernando C, Lai JH: Protein kinase C isoforms in atherosclerosis: pro- or anti-inflammatory? Biochem Pharmacol. 2014 Mar 15; 2014 Jan 16. PMID: 24440741

Chamorro-Jorganes A, Araldi E, Rotllan N, Cirera-Salinas D, Suárez Y: Autoregulation of glypican-1 by intronic microRNA-149 fine tunes the angiogenic response to FGF2 in human endothelial cells. J Cell Sci. 2014 Mar 15; 2014 Jan 24. PMID: 24463821

Cao J, Liu Z, Cheung WK, Zhao M, Chen SY, Chan SW, Booth CJ, Nguyen DX, Yan Q: Histone demethylase RBP2 is critical for breast cancer progression and metastasis. Cell Rep. 2014 Mar 13; 2014 Feb 27. PMID: 24582965

Zhou HJ, Chen X, Huang Q, Liu R, Zhang H, Wang Y, Jin Y, Liang X, Lu L, Xu Z, Min W: AIP1 mediates vascular endothelial cell growth factor receptor-3-dependent angiogenic and lymphangiogenic responses. Arterioscler Thromb Vasc Biol. 2014 Mar; 2014 Jan 9. PMID: 24407031

Schlessinger J: Receptor tyrosine kinases: legacy of the first two decades. Cold Spring Harb Perspect Biol. 2014 Mar 1; 2014 Mar 1. PMID: 24591517

Rivera-Gonzalez G, Shook B, Horsley V: Adipocytes in skin health and disease. Cold Spring Harb Perspect Med. 2014 Mar 1; 2014 Mar 1. PMID: 24591537

Chai TC, Richter HE, Moalli P, Keay S, Biggio J, Zong W, Curto T, Kim HY, Stoddard AM, Kusek JW: Inflammatory and tissue remodeling urinary biomarkers before and after mid urethral sling surgery for stress urinary incontinence. J Urol. 2014 Mar; 2013 Oct 16. PMID: 24140551

Choi J, Landrette SF, Wang T, Evans P, Bacchiocchi A, Bjornson R, Cheng E, Stiegler AL, Gathiaka S, Acevedo O, Boggon TJ, Krauthammer M, Halaban R, Xu T: Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors. Pigment Cell Melanoma Res. 2014 Mar; 2014 Jan 6. PMID: 24283590

Crawford ED, Stone NN, Yu EY, Koo PJ, Freedland SJ, Slovin SF, Gomella LG, Berger ER, Keane TE, Sieber P, Shore ND, Petrylak DP, Prostate Cancer Radiographic Assessments for Detection of Advanced Recurrence (RADAR) Group.: Challenges and recommendations for early identification of metastatic disease in prostate cancer. Urology. 2014 Mar; 2014 Jan 8. PMID: 24411213

Yang Y, Jin X, Jiang C: S-glutathionylation of ion channels: insights into the regulation of channel functions, thiol modification crosstalk, and mechanosensing. Antioxid Redox Signal. 2014 Feb 20; 2013 Aug 20. PMID: 23834398

Fan J, Shan C, Kang HB, Elf S, Xie J, Tucker M, Gu TL, Aguiar M, Lonning S, Chen H, Mohammadi M, Britton LM, Garcia BA, Alečković M, Kang Y, Kaluz S, Devi N, Van Meir EG, Hitosugi T, Seo JH, Lonial S, Gaddh M, Arellano M, Khoury HJ, Khuri FR, Boggon TJ, Kang S, Chen J: Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex. Mol Cell. 2014 Feb 20; 2014 Jan 30. PMID: 24486017

Forloni M, Dogra SK, Dong Y, Conte D Jr, Ou J, Zhu LJ, Deng A, Mahalingam M, Green MR, Wajapeyee N: miR-146a promotes the initiation and progression of melanoma by activating Notch signaling. Elife. 2014 Feb 18; 2014 Feb 18. PMID: 24550252

Draheim KM, Fisher OS, Boggon TJ, Calderwood DA: Cerebral cavernous malformation proteins at a glance. J Cell Sci. 2014 Feb 15; 2014 Jan 30. PMID: 24481819

Guo S, Zi X, Schulz VP, Cheng J, Zhong M, Koochaki SH, Megyola CM, Pan X, Heydari K, Weissman SM, Gallagher PG, Krause DS, Fan R, Lu J: Nonstochastic reprogramming from a privileged somatic cell state. Cell. 2014 Feb 13; 2014 Jan 30. PMID: 24486105

Morse EM, Brahme NN, Calderwood DA: Integrin cytoplasmic tail interactions. Biochemistry. 2014 Feb 11; 2014 Jan 27. PMID: 24467163

Papinski D, Schuschnig M, Reiter W, Wilhelm L, Barnes CA, Maiolica A, Hansmann I, Pfaffenwimmer T, Kijanska M, Stoffel I, Lee SS, Brezovich A, Lou JH, Turk BE, Aebersold R, Ammerer G, Peter M, Kraft C: Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase. Mol Cell. 2014 Feb 6; 2014 Jan 16. PMID: 24440502

Tomko RJ Jr, Hochstrasser M: The intrinsically disordered Sem1 protein functions as a molecular tether during proteasome lid biogenesis. Mol Cell. 2014 Feb 6; 2014 Jan 9. PMID: 24412063

Opatowsky Y, Lax I, Tomé F, Bleichert F, Unger VM, Schlessinger J: Structure, domain organization, and different conformational states of stem cell factor-induced intact KIT dimers. Proc Natl Acad Sci U S A. 2014 Feb 4; 2014 Jan 21. PMID: 24449920

Chen J, Wong S, Nathanson MH, Jain D: Evaluation of Barrett esophagus by multiphoton microscopy. Arch Pathol Lab Med. 2014 Feb. PMID: 24476518

Schalper KA, Kumar S, Hui P, Rimm DL, Gershkovich P: A retrospective population-based comparison of HER2 immunohistochemistry and fluorescence in situ hybridization in breast carcinomas: impact of 2007 American Society of Clinical Oncology/College of American Pathologists criteria. Arch Pathol Lab Med. 2014 Feb; 2013 Oct 28. PMID: 24164555

Lockwood W, Politi K: MYCxing it up with FGFR1 in squamous cell lung cancer. Cancer Discov. 2014 Feb. PMID: 24501305

Pirazzoli V, Politi K: Generation of drug-resistant tumors using intermittent dosing of tyrosine kinase inhibitors in mouse. Cold Spring Harb Protoc. 2014 Feb 1; 2014 Feb 1. PMID: 24492774

Chen C, Ha BH, Thévenin AF, Lou HJ, Zhang R, Yip KY, Peterson JR, Gerstein M, Kim PM, Filippakopoulos P, Knapp S, Boggon TJ, Turk BE: Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity. Mol Cell. 2014 Jan 9; 2013 Dec 26. PMID: 24374310

Qin L, Huang Q, Zhang H, Liu R, Tellides G, Min W, Yu L: SOCS1 prevents graft arteriosclerosis by preserving endothelial cell function. J Am Coll Cardiol. 2014 Jan 7-14; 2013 Aug 28. PMID: 23994402

Chacón KM, Petti LM, Scheideman EH, Pirazzoli V, Politi K, DiMaio D: De novo selection of oncogenes. Proc Natl Acad Sci U S A. 2014 Jan 7; 2013 Dec 16. PMID: 24344264

Yang Y, Konduru AS, Cui N, Yu L, Trower TC, Shi W, Shi Y, Jiang C: Acute exposure of methylglyoxal leads to activation of KATP channels expressed in HEK293 cells. Acta Pharmacol Sin. 2014 Jan; 2013 Oct 14. PMID: 24122011

Sternberg CN, Petrylak DP, Madan RA, Parker C: Progress in the treatment of advanced prostate cancer. Am Soc Clin Oncol Educ Book. 2014. PMID: 24857068

Chen X, Zhou HJ, Huang Q, Lu L, Min W: Novel action and mechanism of auranofin in inhibition of vascular endothelial growth factor receptor-3-dependent lymphangiogenesis. Anticancer Agents Med Chem. 2014. PMID: 24913775

Kunjappu MJ, Hochstrasser M: Assembly of the 20S proteasome. Biochim Biophys Acta. 2014 Jan; 2013 Mar 16. PMID: 23507199

Keay SK, Birder LA, Chai TC: Evidence for bladder urothelial pathophysiology in functional bladder disorders. Biomed Res Int. 2014; 2014 May 8. PMID: 24900993

Tadeu AM, Horsley V: Epithelial stem cells in adult skin. Curr Top Dev Biol. 2014. PMID: 24439804

Amaya MJ, Oliveira AG, Guimarães ES, Casteluber MC, Carvalho SM, Andrade LM, Pinto MC, Mennone A, Oliveira CA, Resende RR, Menezes GB, Nathanson MH, Leite MF: The insulin receptor translocates to the nucleus to regulate cell proliferation in liver. Hepatology. 2014 Jan; 2013 Jul 29. PMID: 23839970

Velcheti V, Schalper KA, Carvajal DE, Anagnostou VK, Syrigos KN, Sznol M, Herbst RS, Gettinger SN, Chen L, Rimm DL: Programmed death ligand-1 expression in non-small cell lung cancer. Lab Invest. 2014 Jan; 2013 Nov 11. PMID: 24217091

Brown JR, DiGiovanna MP, Killelea B, Lannin DR, Rimm DL: Quantitative assessment Ki-67 score for prediction of response to neoadjuvant chemotherapy in breast cancer. Lab Invest. 2014 Jan; 2013 Nov 4. PMID: 24189270

Evans P, Kong Y, Krauthammer M: Computational analysis in cancer exome sequencing. Methods Mol Biol. 2014. PMID: 25030931

Hurwitz ME: Clonal screens to find modifiers of partially penetrant phenotypes in C. elegans. Methods Mol Biol. 2014. PMID: 25030926

Nagarajan A, Roden C, Wajapeyee N: Reduced representation bisulfite sequencing to identify global alteration of DNA methylation. Methods Mol Biol. 2014. PMID: 25030916

Rothberg BE, Rimm DL: Construction and analysis of multiparameter prognostic models for melanoma outcome. Methods Mol Biol. 2014. PMID: 24258982

Martin DT, Steinbach JM, Liu J, Shimizu S, Kaimakliotis HZ, Wheeler MA, Hittelman AB, Mark Saltzman W, Weiss RM: Surface-modified nanoparticles enhance transurothelial penetration and delivery of survivin siRNA in treating bladder cancer. Mol Cancer Ther. 2014 Jan; 2013 Nov 12. PMID: 24222663

Befroy DE, Perry RJ, Jain N, Dufour S, Cline GW, Trimmer JK, Brosnan J, Rothman DL, Petersen KF, Shulman GI: Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy. Nat Med. 2014 Jan; 2013 Dec 8. PMID: 24317120

Kerrisk ME, Cingolani LA, Koleske AJ: ECM receptors in neuronal structure, synaptic plasticity, and behavior. Prog Brain Res. 2014. PMID: 25410355

Rompolas P, Greco V: Stem cell dynamics in the hair follicle niche. Semin Cell Dev Biol. 2014 Jan-Feb; 2013 Dec 17. PMID: 24361866

Petrylak DP: Challenges in treating advanced disease. Am J Manag Care. 2013 Dec. PMID: 24494691

Petrylak DP: Current state of castration-resistant prostate cancer. Am J Manag Care. 2013 Dec. PMID: 24494690

Ruan HB, Nie Y, Yang X: Regulation of protein degradation by O-GlcNAcylation: crosstalk with ubiquitination. Mol Cell Proteomics. 2013 Dec; 2013 Jul 3. PMID: 23824911

Sá-Moura B, Funakoshi M, Tomko RJ Jr, Dohmen RJ, Wu Z, Peng J, Hochstrasser M: A conserved protein with AN1 zinc finger and ubiquitin-like domains modulates Cdc48 (p97) function in the ubiquitin-proteasome pathway. J Biol Chem. 2013 Nov 22; 2013 Oct 11. PMID: 24121501

Bai Y, Cheng H, Bordeaux J, Neumeister V, Kumar S, Rimm DL, Stern DF: Comparison of HER2 and phospho-HER2 expression between biopsy and resected breast cancer specimens using a quantitative assessment method. PLoS One. 2013; 2013 Nov 21. PMID: 24278211

Halabi S, Lin CY, Small EJ, Armstrong AJ, Kaplan EB, Petrylak D, Sternberg CN, Shen L, Oudard S, de Bono J, Sartor O: Prognostic model predicting metastatic castration-resistant prostate cancer survival in men treated with second-line chemotherapy. J Natl Cancer Inst. 2013 Nov 20; 2013 Oct 17. PMID: 24136890

Jouret F, Wu J, Hull M, Rajendran V, Mayr B, Schöfl C, Geibel J, Caplan MJ: Activation of the Ca²+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membrane. J Cell Sci. 2013 Nov 15; 2013 Sep 6. PMID: 24013548

Jonas S, Zhou E, Deniz E, Huang B, Chandrasekera K, Bhattacharya D, Wu Y, Fan R, Deserno TM, Khokha MK, Choma MA: A novel approach to quantifying ciliary physiology: microfluidic mixing driven by a ciliated biological surface. Lab Chip. 2013 Nov 7. PMID: 23970350

Perry RJ, Kim T, Zhang XM, Lee HY, Pesta D, Popov VB, Zhang D, Rahimi Y, Jurczak MJ, Cline GW, Spiegel DA, Shulman GI: Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler. Cell Metab. 2013 Nov 5. PMID: 24206666

Shibata S, Rinehart J, Zhang J, Moeckel G, Castañeda-Bueno M, Stiegler AL, Boggon TJ, Gamba G, Lifton RP: Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia. Cell Metab. 2013 Nov 5. PMID: 24206662

Perry RJ, Shulman GI: Treating fatty liver and insulin resistance. Aging (Albany NY). 2013 Nov. PMID: 24304662

Collaco AM, Geibel P, Lee BS, Geibel JP, Ameen NA: Functional vacuolar ATPase (V-ATPase) proton pumps traffic to the enterocyte brush border membrane and require CFTR. Am J Physiol Cell Physiol. 2013 Nov 1; 2013 Aug 28. PMID: 23986201

Viray H, Li K, Long TA, Vasalos P, Bridge JA, Jennings LJ, Halling KC, Hameed M, Rimm DL: A prospective, multi-institutional diagnostic trial to determine pathologist accuracy in estimation of percentage of malignant cells. Arch Pathol Lab Med. 2013 Nov. PMID: 24168492

Kerrisk ME, Koleske AJ: Arg kinase signaling in dendrite and synapse stabilization pathways: memory, cocaine sensitivity, and stress. Int J Biochem Cell Biol. 2013 Nov; 2013 Aug 2. PMID: 23916785

Martin DT, Hoimes CJ, Kaimakliotis HZ, Cheng CJ, Zhang K, Liu J, Wheeler MA, Kelly WK, Tew GN, Saltzman WM, Weiss RM: Nanoparticles for urothelium penetration and delivery of the histone deacetylase inhibitor belinostat for treatment of bladder cancer. Nanomedicine. 2013 Nov; 2013 Jun 11. PMID: 23764660

Hurwitz M, Petrylak DP: Sequencing of agents for castration-resistant prostate cancer. Oncology (Williston Park). 2013 Nov. PMID: 24575543

Reshetnyak AV, Nelson B, Shi X, Boggon TJ, Pavlenco A, Mandel-Bausch EM, Tome F, Suzuki Y, Sidhu SS, Lax I, Schlessinger J: Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region. Proc Natl Acad Sci U S A. 2013 Oct 29; 2013 Oct 14. PMID: 24127596

Zhang Y, Tang W, Zhang H, Niu X, Xu Y, Zhang J, Gao K, Pan W, Boggon TJ, Toomre D, Min W, Wu D: A network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils. Dev Cell. 2013 Oct 28. PMID: 24176643

Gao J, Ha BH, Lou HJ, Morse EM, Zhang R, Calderwood DA, Turk BE, Boggon TJ: Substrate and inhibitor specificity of the type II p21-activated kinase, PAK6. PLoS One. 2013; 2013 Oct 28. PMID: 24204982

Rompolas P, Mesa KR, Greco V: Spatial organization within a niche as a determinant of stem-cell fate. Nature. 2013 Oct 24; 2013 Oct 6. PMID: 24097351

Mao L, Shen L, Niu J, Zhang J, Ding W, Wu Y, Fan R, Yuan G: Nanophasic biodegradation enhances the durability and biocompatibility of magnesium alloys for the next-generation vascular stents. Nanoscale. 2013 Oct 21. PMID: 23989064

Yang Y, Vasylyev DV, Dib-Hajj F, Veeramah KR, Hammer MF, Dib-Hajj SD, Waxman SG: Multistate structural modeling and voltage-clamp analysis of epilepsy/autism mutation Kv10.2-R327H demonstrate the role of this residue in stabilizing the channel closed state. J Neurosci. 2013 Oct 16. PMID: 24133262

Wajapeyee N, Malonia SK, Palakurthy RK, Green MR: Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors. Genes Dev. 2013 Oct 15; 2013 Oct 8. PMID: 24105743

Li Q, Canosa S, Flynn K, Michaud M, Krauthammer M, Madri JA: Modeling the neurovascular niche: unbiased transcriptome analysis of the murine subventricular zone in response to hypoxic insult. PLoS One. 2013; 2013 Oct 11. PMID: 24146847

Kallen AN, Zhou XB, Xu J, Qiao C, Ma J, Yan L, Lu L, Liu C, Yi JS, Zhang H, Min W, Bennett AM, Gregory RI, Ding Y, Huang Y: The imprinted H19 lncRNA antagonizes let-7 microRNAs. Mol Cell. 2013 Oct 10; 2013 Sep 19. PMID: 24055342

Galbo T, Perry RJ, Nishimura E, Samuel VT, Quistorff B, Shulman GI: PP2A inhibition results in hepatic insulin resistance despite Akt2 activation. Aging (Albany NY). 2013 Oct. PMID: 24150286

Ross TD, Coon BG, Yun S, Baeyens N, Tanaka K, Ouyang M, Schwartz MA: Integrins in mechanotransduction. Curr Opin Cell Biol. 2013 Oct; 2013 Jun 21. PMID: 23797029

Malkhasyan K, Deshpande HA, Adeniran AJ, Colberg JW, Petrylak DP: The use of serum hCG as a marker of tumor progression and of the response of metastatic urothelial cancer to systemic chemotherapy. Oncology (Williston Park). 2013 Oct. PMID: 24367863

Hu MI, Glezerman I, Leboulleux S, Insogna K, Gucalp R, Misiorowski W, Yu B, Ying W, Jain RK: Denosumab for patients with persistent or relapsed hypercalcemia of malignancy despite recent bisphosphonate treatment. J Natl Cancer Inst. 2013 Sep 18; 2013 Aug 29. PMID: 23990665

Sizova D, Velazquez H, Sampaio-Maia B, Quelhas-Santos J, Pestana M, Desir GV: Renalase regulates renal dopamine and phosphate metabolism. Am J Physiol Renal Physiol. 2013 Sep 15; 2013 Jul 17. PMID: 23863468

Um JW, Kaufman AC, Kostylev M, Heiss JK, Stagi M, Takahashi H, Kerrisk ME, Vortmeyer A, Wisniewski T, Koleske AJ, Gunther EC, Nygaard HB, Strittmatter SM: Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein. Neuron. 2013 Sep 4. PMID: 24012003

Roginiel AC, Kohut DL, Kaur S, Saleh AM, Weber T, Geibel P, Singh H, Geibel JP: Effect of NSAIDs on Na⁺/H⁺ exchanger activity in rat colonic crypts. Am J Physiol Cell Physiol. 2013 Sep; 2013 Jun 5. PMID: 23739181

Tadeu AM, Horsley V: Notch signaling represses p63 expression in the developing surface ectoderm. Development. 2013 Sep; 2013 Aug 7. PMID: 23924630

Mamillapalli R, VanHouten J, Dann P, Bikle D, Chang W, Brown E, Wysolmerski J: Mammary-specific ablation of the calcium-sensing receptor during lactation alters maternal calcium metabolism, milk calcium transport, and neonatal calcium accrual. Endocrinology. 2013 Sep; 2013 Jun 19. PMID: 23782944

Evans P, Avey S, Kong Y, Krauthammer M: Adjusting for background mutation frequency biases improves the identification of cancer driver genes. IEEE Trans Nanobioscience. 2013 Sep; 2013 May 16. PMID: 23694700

Dufresne ER, Schwartz MA: Cell migration: Towards the void. Nat Mater. 2013 Sep. PMID: 23966050

Alicea-Velazquez NL, Boggon TJ: SHP family protein tyrosine phosphatases adopt canonical active-site conformations in the apo and phosphate-bound states. Protein Pept Lett. 2013 Sep. PMID: 23514039

Wei W, Shin YS, Ma C, Wang J, Elitas M, Fan R, Heath JR: Microchip platforms for multiplex single-cell functional proteomics with applications to immunology and cancer research. Genome Med. 2013; 2013 Aug 29. PMID: 23998271

Huang J, Yang Y, Zhao P, Gerrits MM, Hoeijmakers JG, Bekelaar K, Merkies IS, Faber CG, Dib-Hajj SD, Waxman SG: Small-fiber neuropathy Nav1.8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons. J Neurosci. 2013 Aug 28. PMID: 23986244

Li M, Sun Y, Tomiya N, Hsu Y, Chai TC: Elevated polyamines in urothelial cells from OAB subjects mediate oxotremorine-evoked rapid intracellular calcium rise and delayed acetylcholine release. Am J Physiol Renal Physiol. 2013 Aug 15; 2013 May 22. PMID: 23698115

Breindel JL, Haskins JW, Cowell EP, Zhao M, Nguyen DX, Stern DF: EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis. Cancer Res. 2013 Aug 15; 2013 Jun 21. PMID: 23794705

Jilaveanu LB, Zhao F, Zito CR, Kirkwood JM, Nathanson KL, D'Andrea K, Wilson M, Rimm DL, Flaherty KT, Lee SJ, Kluger HM: Expression of drug targets in patients treated with sorafenib, carboplatin and paclitaxel. PLoS One. 2013; 2013 Aug 6. PMID: 23936348

Bosurgi L, Bernink JH, Delgado Cuevas V, Gagliani N, Joannas L, Schmid ET, Booth CJ, Ghosh S, Rothlin CV: Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer. Proc Natl Acad Sci U S A. 2013 Aug 6; 2013 Jul 22. PMID: 23878224

Viray H, Bradley WR, Schalper KA, Rimm DL, Gould Rothberg BE: Marginal and joint distributions of S100, HMB-45, and Melan-A across a large series of cutaneous melanomas. Arch Pathol Lab Med. 2013 Aug. PMID: 23899062

Calderwood DA, Campbell ID, Critchley DR: Talins and kindlins: partners in integrin-mediated adhesion. Nat Rev Mol Cell Biol. 2013 Aug; 2013 Jul 17. PMID: 23860236

Koleske AJ: Molecular mechanisms of dendrite stability. Nat Rev Neurosci. 2013 Aug; 2013 Jul 10. PMID: 23839597

Galbo T, Perry RJ, Jurczak MJ, Camporez JP, Alves TC, Kahn M, Guigni BA, Serr J, Zhang D, Bhanot S, Samuel VT, Shulman GI: Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signaling and ceramide synthesis in vivo. Proc Natl Acad Sci U S A. 2013 Jul 30; 2013 Jul 9. PMID: 23840067

Carrera Silva EA, Chan PY, Joannas L, Errasti AE, Gagliani N, Bosurgi L, Jabbour M, Perry A, Smith-Chakmakova F, Mucida D, Cheroutre H, Burstyn-Cohen T, Leighton JA, Lemke G, Ghosh S, Rothlin CV: T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response. Immunity. 2013 Jul 25; 2013 Jul 11. PMID: 23850380

Yang Y, Paspalas CD, Jin LE, Picciotto MR, Arnsten AF, Wang M: Nicotinic α7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex. Proc Natl Acad Sci U S A. 2013 Jul 16; 2013 Jul 1. PMID: 23818597

Chen W, Huang NT, Oh B, Lam RHW, Fan R, Cornell TT, Shanley TP, Kurabayashi K, Fu J: Surface-micromachined microfiltration membranes for efficient isolation and functional immunophenotyping of subpopulations of immune cells. Adv Healthc Mater. 2013 Jul; 2013 Jan 20. PMID: 23335389

McCusker JP, Lebo T, Krauthammer M, McGuinness DL: Next Generation Cancer Data Discovery, Access, and Integration Using Prizms and Nanopublications. Data Integr Life Sci. 2013 Jul. PMID: 27631029

Huang F, Hartwich TM, Rivera-Molina FE, Lin Y, Duim WC, Long JJ, Uchil PD, Myers JR, Baird MA, Mothes W, Davidson MW, Toomre D, Bewersdorf J: Video-rate nanoscopy using sCMOS camera-specific single-molecule localization algorithms. Nat Methods. 2013 Jul; 2013 May 26. PMID: 23708387

Gustavson MD, Rimm DL, Dolled-Filhart M: Tissue microarrays: leaping the gap between research and clinical adoption. Per Med. 2013 Jul. PMID: 29758838

Tworkoski KA, Platt JT, Bacchiocchi A, Bosenberg M, Boggon TJ, Stern DF: MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL. Pigment Cell Melanoma Res. 2013 Jul; 2013 May 21. PMID: 23617806

Cheung WK, Zhao M, Liu Z, Stevens LE, Cao PD, Fang JE, Westbrook TF, Nguyen DX: Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis. Cancer Cell. 2013 Jun 10; 2013 May 23. PMID: 23707782

Vanhouten JN, Wysolmerski JJ: The calcium-sensing receptor in the breast. Best Pract Res Clin Endocrinol Metab. 2013 Jun; 2013 Mar 28. PMID: 23856268

Wysolmerski JJ: Osteocytes remove and replace perilacunar mineral during reproductive cycles. Bone. 2013 Jun; 2013 Jan 23. PMID: 23352996

Petrylak D: Lower baseline PSA predicts greater benefit from sipuleucel-T. Clin Adv Hematol Oncol. 2013 Jun. PMID: 24472808

Thomas CE, Gaffney-Stomberg E, Sun BH, O'Brien KO, Kerstetter JE, Insogna KL: Increasing dietary protein acutely augments intestinal iron transporter expression and significantly increases iron absorption in rats. FASEB J. 2013 Jun; 2013 Feb 27. PMID: 23447582

Fodeh SJ, Brandt C, Luong TB, Haddad A, Schultz M, Murphy T, Krauthammer M: Complementary ensemble clustering of biomedical data. J Biomed Inform. 2013 Jun; 2013 Feb 27. PMID: 23454721

Velcheti V, Rimm DL, Schalper KA: Sarcomatoid lung carcinomas show high levels of programmed death ligand-1 (PD-L1). J Thorac Oncol. 2013 Jun. PMID: 23676558

Ruan HB, Singh JP, Li MD, Wu J, Yang X: Cracking the O-GlcNAc code in metabolism. Trends Endocrinol Metab. 2013 Jun; 2013 May 4. PMID: 23647930

Rivera-Molina F, Toomre D: Live-cell imaging of exocyst links its spatiotemporal dynamics to various stages of vesicle fusion. J Cell Biol. 2013 May 27; 2013 May 20. PMID: 23690179

Qin L, Yu L, Min W: Mouse models for graft arteriosclerosis. J Vis Exp. 2013 May 14; 2013 May 14. PMID: 23712086

Barmeyer C, Ye JH, Soroka C, Geibel P, Hingsammer LM, Weitgasser L, Atway D, Geibel JP, Binder HJ, Rajendran VM: Identification of functionally distinct Na-HCO3 co-transporters in colon. PLoS One. 2013; 2013 May 14. PMID: 23690961

Yang Y, Estacion M, Dib-Hajj SD, Waxman SG: Molecular architecture of a sodium channel S6 helix: radial tuning of the voltage-gated sodium channel 1.7 activation gate. J Biol Chem. 2013 May 10; 2013 Mar 27. PMID: 23536180

Liu W, Boggon TJ: Cocrystal structure of the ICAP1 PTB domain in complex with a KRIT1 peptide. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 May 1; 2013 Apr 27. PMID: 23695561

Shi H, Verma M, Zhang L, Dong C, Flavell RA, Bennett AM: Improved regenerative myogenesis and muscular dystrophy in mice lacking Mkp5. J Clin Invest. 2013 May; 2013 Apr 1. PMID: 23543058

McGee HM, Schmidt BA, Booth CJ, Yancopoulos GD, Valenzuela DM, Murphy AJ, Stevens S, Flavell RA, Horsley V: IL-22 promotes fibroblast-mediated wound repair in the skin. J Invest Dermatol. 2013 May; 2012 Dec 6. PMID: 23223145

Lanahan A, Zhang X, Fantin A, Zhuang Z, Rivera-Molina F, Speichinger K, Prahst C, Zhang J, Wang Y, Davis G, Toomre D, Ruhrberg C, Simons M: The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis. Dev Cell. 2013 Apr 29. PMID: 23639442

Mesa KR, Greco V: Linking morphogen and chromatin in the hair follicle. Dev Cell. 2013 Apr 29. PMID: 23639438

Velcheti V, Schalper K, Yao X, Cheng H, Kocoglu M, Dhodapkar K, Deng Y, Gettinger S, Rimm DL: High SOX2 levels predict better outcome in non-small cell lung carcinomas. PLoS One. 2013; 2013 Apr 19. PMID: 23620753

Kerrisk ME, Greer CA, Koleske AJ: Integrin α3 is required for late postnatal stability of dendrite arbors, dendritic spines and synapses, and mouse behavior. J Neurosci. 2013 Apr 17. PMID: 23595732

Couch BA, Kerrisk ME, Kaufman AC, Nygaard HB, Strittmatter SM, Koleske AJ: Delayed amyloid plaque deposition and behavioral deficits in outcrossed AβPP/PS1 mice. J Comp Neurol. 2013 Apr 15. PMID: 23047754

Kwak M, Mu L, Lu Y, Chen JJ, Wu Y, Brower K, Fan R: Erratum: single-cell protein secretomic signatures as potential correlates to tumor cell lineage evolution and cell-cell interaction. Front Oncol. 2013; 2013 Apr 8. PMID: 23579430

Huang Q, Qin L, Dai S, Zhang H, Pasula S, Zhou H, Chen H, Min W: AIP1 suppresses atherosclerosis by limiting hyperlipidemia-induced inflammation and vascular endothelial dysfunction. Arterioscler Thromb Vasc Biol. 2013 Apr; 2013 Feb 14. PMID: 23413429

Peixoto AJ, Orias M, Desir GV: Does kidney disease cause hypertension? Curr Hypertens Rep. 2013 Apr. PMID: 23344662

Schmidt BA, Horsley V: Intradermal adipocytes mediate fibroblast recruitment during skin wound healing. Development. 2013 Apr. PMID: 23482487

Zattas D, Adle DJ, Rubenstein EM, Hochstrasser M: N-terminal acetylation of the yeast Derlin Der1 is essential for Hrd1 ubiquitin-ligase activity toward luminal ER substrates. Mol Biol Cell. 2013 Apr; 2013 Jan 30. PMID: 23363603

Lee H, Bennett AM: Receptor protein tyrosine phosphatase-receptor tyrosine kinase substrate screen identifies EphA2 as a target for LAR in cell migration. Mol Cell Biol. 2013 Apr; 2013 Jan 28. PMID: 23358419

Welsh AW, Harigopal M, Wimberly H, Prasad M, Rimm DL: Quantitative analysis of estrogen receptor expression shows SP1 antibody is more sensitive than 1D5. Appl Immunohistochem Mol Morphol. 2013 Mar. PMID: 22820659

Estacion M, Yang Y, Dib-Hajj SD, Tyrrell L, Lin Z, Yang Y, Waxman SG: A new Nav1.7 mutation in an erythromelalgia patient. Biochem Biophys Res Commun. 2013 Mar 1; 2013 Jan 30. PMID: 23376079

Dolled-Filhart MP, Rimm DL: Gene expression array analysis to determine tissue of origin of carcinoma of unknown primary: cutting edge or already obsolete? Cancer Cytopathol. 2013 Mar; 2012 Aug 23. PMID: 22927160

Hahn LD, Hoyt C, Rimm DL, Theoharis C: Spatial spectral imaging as an adjunct to the Bethesda classification of thyroid fine-needle aspiration specimens. Cancer Cytopathol. 2013 Mar; 2012 Jul 25. PMID: 22833451

Bruce C, Stone K, Gulcicek E, Williams K: Proteomics and the analysis of proteomic data: 2013 overview of current protein-profiling technologies. Curr Protoc Bioinformatics. 2013 Mar. PMID: 23504934

Bihuniak JD, Simpson CA, Sullivan RR, Caseria DM, Kerstetter JE, Insogna KL: Dietary protein-induced increases in urinary calcium are accompanied by similar increases in urinary nitrogen and urinary urea: a controlled clinical trial. J Acad Nutr Diet. 2013 Mar. PMID: 23438496

Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK: Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar; 2013 Feb 28. PMID: 23449535

Alicea-Velázquez NL, Jakoncic J, Boggon TJ: Structure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognition. J Struct Biol. 2013 Mar; 2013 Jan 4. PMID: 23296072

Bilguvar K, Tyagi NK, Ozkara C, Tuysuz B, Bakircioglu M, Choi M, Delil S, Caglayan AO, Baranoski JF, Erturk O, Yalcinkaya C, Karacorlu M, Dincer A, Johnson MH, Mane S, Chandra SS, Louvi A, Boggon TJ, Lifton RP, Horwich AL, Gunel M: Recessive loss of function of the neuronal ubiquitin hydrolase UCHL1 leads to early-onset progressive neurodegeneration. Proc Natl Acad Sci U S A. 2013 Feb 26; 2013 Jan 28. PMID: 23359680

Liu W, Draheim KM, Zhang R, Calderwood DA, Boggon TJ: Mechanism for KRIT1 release of ICAP1-mediated suppression of integrin activation. Mol Cell. 2013 Feb 21; 2013 Jan 11. PMID: 23317506

Wang M, Yang Y, Wang CJ, Gamo NJ, Jin LE, Mazer JA, Morrison JH, Wang XJ, Arnsten AF: NMDA receptors subserve persistent neuronal firing during working memory in dorsolateral prefrontal cortex. Neuron. 2013 Feb 20. PMID: 23439125

Lu Y, Chen JJ, Mu L, Xue Q, Wu Y, Wu PH, Li J, Vortmeyer AO, Miller-Jensen K, Wirtz D, Fan R: High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity. Anal Chem. 2013 Feb 19; 2013 Feb 1. PMID: 23339603

Zhao S, Choi M, Overton JD, Bellone S, Roque DM, Cocco E, Guzzo F, English DP, Varughese J, Gasparrini S, Bortolomai I, Buza N, Hui P, Abu-Khalaf M, Ravaggi A, Bignotti E, Bandiera E, Romani C, Todeschini P, Tassi R, Zanotti L, Carrara L, Pecorelli S, Silasi DA, Ratner E, Azodi M, Schwartz PE, Rutherford TJ, Stiegler AL, Mane S, Boggon TJ, Schlessinger J, Lifton RP, Santin AD: Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma. Proc Natl Acad Sci U S A. 2013 Feb 19; 2013 Jan 28. PMID: 23359684

Kwak M, Mu L, Lu Y, Chen JJ, Brower K, Fan R: Single-cell protein secretomic signatures as potential correlates to tumor cell lineage evolution and cell-cell interaction. Front Oncol. 2013; 2013 Feb 6. PMID: 23390614

Li MD, Ruan HB, Hughes ME, Lee JS, Singh JP, Jones SP, Nitabach MN, Yang X: O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination. Cell Metab. 2013 Feb 5. PMID: 23395176

Flannery CA, Rackow B, Cong X, Duran E, Selen DJ, Burgert TS: Polycystic ovary syndrome in adolescence: impaired glucose tolerance occurs across the spectrum of BMI. Pediatr Diabetes. 2013 Feb; 2012 Aug 28. PMID: 22925367

Fisher OS, Zhang R, Li X, Murphy JW, Demeler B, Boggon TJ: Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus. FEBS Lett. 2013 Jan 31; 2012 Dec 22. PMID: 23266514

Lin YC, Yeckel MF, Koleske AJ: Abl2/Arg controls dendritic spine and dendrite arbor stability via distinct cytoskeletal control pathways. J Neurosci. 2013 Jan 30. PMID: 23365224

Schwartz MA, Chen CS: Cell biology. Deconstructing dimensionality. Science. 2013 Jan 25. PMID: 23349278

Davis MJ, Ha BH, Holman EC, Halaban R, Schlessinger J, Boggon TJ: RAC1P29S is a spontaneously activating cancer-associated GTPase. Proc Natl Acad Sci U S A. 2013 Jan 15; 2013 Jan 2. PMID: 23284172

Mertz AF, Che Y, Banerjee S, Goldstein JM, Rosowski KA, Revilla SF, Niessen CM, Marchetti MC, Dufresne ER, Horsley V: Cadherin-based intercellular adhesions organize epithelial cell-matrix traction forces. Proc Natl Acad Sci U S A. 2013 Jan 15; 2012 Dec 31. PMID: 23277553

Tomko RJ Jr, Hochstrasser M: Molecular architecture and assembly of the eukaryotic proteasome. Annu Rev Biochem. 2013; 2013 Mar 13. PMID: 23495936

Kawano T, Zhu M, Troiano N, Horowitz M, Bian J, Gundberg C, Kolodziejczak K, Insogna K: LIM kinase 1 deficient mice have reduced bone mass. Bone. 2013 Jan; 2012 Sep 24. PMID: 23017662

Held MA, Langdon CG, Platt JT, Graham-Steed T, Liu Z, Chakraborty A, Bacchiocchi A, Koo A, Haskins JW, Bosenberg MW, Stern DF: Genotype-selective combination therapies for melanoma identified by high-throughput drug screening. Cancer Discov. 2013 Jan; 2012 Dec 13. PMID: 23239741

Lawan A, Shi H, Gatzke F, Bennett AM: Diversity and specificity of the mitogen-activated protein kinase phosphatase-1 functions. Cell Mol Life Sci. 2013 Jan; 2012 Jun 14. PMID: 22695679

Amaya MJ, Nathanson MH: Calcium signaling in the liver. Compr Physiol. 2013 Jan. PMID: 23720295

Goldberg SB, Schlessinger J, Boyer JL, Herbst RS: A step towards treating KRAS-mutant NSCLC. Lancet Oncol. 2013 Jan; 2012 Nov 28. PMID: 23200176

Gupta R, Wajapeyee N: Induction of cellular senescence by oncogenic RAS. Methods Mol Biol. 2013. PMID: 23929102

Wajapeyee N, Deibler SK, Green MR: Genome-wide RNAi screening to identify regulators of oncogene-induced cellular senescence. Methods Mol Biol. 2013. PMID: 23296672

Mercan F, Lee H, Kolli S, Bennett AM: Novel role for SHP-2 in nutrient-responsive control of S6 kinase 1 signaling. Mol Cell Biol. 2013 Jan; 2012 Nov 5. PMID: 23129808

Greco V: The death and growth connection. Nat Rev Mol Cell Biol. 2013 Jan; 2012 Dec 5. PMID: 23212474

Dib-Hajj SD, Yang Y, Black JA, Waxman SG: The Na(V)1.7 sodium channel: from molecule to man. Nat Rev Neurosci. 2013 Jan; 2012 Dec 12. PMID: 23232607

Kopic S, Geibel JP: Gastric acid, calcium absorption, and their impact on bone health. Physiol Rev. 2013 Jan. PMID: 23303909

Stiegler AL, Grant TD, Luft JR, Calderwood DA, Snell EH, Boggon TJ: Purification and SAXS analysis of the integrin linked kinase, PINCH, parvin (IPP) heterotrimeric complex. PLoS One. 2013; 2013 Jan 31. PMID: 23383235

Zhou J, Wu Y, Lee SK, Fan R: High-content single-cell analysis on-chip using a laser microarray scanner. Lab Chip. 2012 Dec 7. PMID: 22991099

Wysolmerski JJ: Osteocytic osteolysis: time for a second look? Bonekey Rep. 2012 Dec 5; 2012 Dec 5. PMID: 24363929

Neumeister VM, Anagnostou V, Siddiqui S, England AM, Zarrella ER, Vassilakopoulou M, Parisi F, Kluger Y, Hicks DG, Rimm DL: Quantitative assessment of effect of preanalytic cold ischemic time on protein expression in breast cancer tissues. J Natl Cancer Inst. 2012 Dec 5; 2012 Oct 22. PMID: 23090068

Sherwin R, Slayman C, Rockwell S, Herold K, Williams K, Carson R, Mane S, Seow H, Max J, Johnson T: Yale Center for Clinical Investigation: leveraging industry partnerships and research cores. Clin Transl Sci. 2012 Dec. PMID: 23253663

Stahlhut C, Suárez Y, Lu J, Mishima Y, Giraldez AJ: miR-1 and miR-206 regulate angiogenesis by modulating VegfA expression in zebrafish. Development. 2012 Dec 1. PMID: 23132244

Wu Y, Garmire LX, Fan R: Inter-cellular signaling network reveals a mechanistic transition in tumor microenvironment. Integr Biol (Camb). 2012 Dec. PMID: 23080410

Bouaouina M, Jani K, Long JY, Czerniecki S, Morse EM, Ellis SJ, Tanentzapf G, Schöck F, Calderwood DA: Zasp regulates integrin activation. J Cell Sci. 2012 Dec 1; 2012 Sep 19. PMID: 22992465

Hickey CM, Wilson NR, Hochstrasser M: Function and regulation of SUMO proteases. Nat Rev Mol Cell Biol. 2012 Dec. PMID: 23175280

Tirziu D, Jaba IM, Yu P, Larrivée B, Coon BG, Cristofaro B, Zhuang ZW, Lanahan AA, Schwartz MA, Eichmann A, Simons M: Endothelial nuclear factor-κB-dependent regulation of arteriogenesis and branching. Circulation. 2012 Nov 27; 2012 Oct 22. PMID: 23091063

Deng Y, Couch BA, Koleske AJ, Turk BE: A peptide photoaffinity probe specific for the active conformation of the Abl tyrosine kinase. Chembiochem. 2012 Nov 26; 2012 Oct 18. PMID: 23081945

Neumeister VM, Sullivan CA, Lindner R, Lezon-Geyda K, Li J, Zavada J, Martel M, Glazer PM, Tuck DP, Rimm DL, Harris L: Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein and pathway activity in triple negative breast cancer. Breast Cancer Res Treat. 2012 Nov; 2012 Sep 14. PMID: 22976806

Flannery C, Dufour S, Rabøl R, Shulman GI, Petersen KF: Skeletal muscle insulin resistance promotes increased hepatic de novo lipogenesis, hyperlipidemia, and hepatic steatosis in the elderly. Diabetes. 2012 Nov; 2012 Jul 24. PMID: 22829450

Schmidt B, Horsley V: Unravelling hair follicle-adipocyte communication. Exp Dermatol. 2012 Nov. PMID: 23163647

Desir GV, Wang L, Peixoto AJ: Human renalase: a review of its biology, function, and implications for hypertension. J Am Soc Hypertens. 2012 Nov-Dec; 2012 Oct 26. PMID: 23107895

Lee YJ, Jeschke GR, Roelants FM, Thorner J, Turk BE: Reciprocal phosphorylation of yeast glycerol-3-phosphate dehydrogenases in adaptation to distinct types of stress. Mol Cell Biol. 2012 Nov; 2012 Sep 17. PMID: 22988299

Wong A, Zhang YW, Jeschke GR, Turk BE, Rudnick G: Cyclic GMP-dependent stimulation of serotonin transport does not involve direct transporter phosphorylation by cGMP-dependent protein kinase. J Biol Chem. 2012 Oct 19; 2012 Aug 31. PMID: 22942288

Ha BH, Davis MJ, Chen C, Lou HJ, Gao J, Zhang R, Krauthammer M, Halaban R, Schlessinger J, Turk BE, Boggon TJ: Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate. Proc Natl Acad Sci U S A. 2012 Oct 2; 2012 Sep 17. PMID: 22988085

Dimou A, Neumeister V, Agarwal S, Anagnostou V, Syrigos K, Rimm DL: Measurement of aldehyde dehydrogenase 1 expression defines a group with better prognosis in patients with non-small cell lung cancer. Am J Pathol. 2012 Oct; 2012 Aug 8. PMID: 22877687

Baquero MT, Hanna JA, Neumeister V, Cheng H, Molinaro AM, Harris LN, Rimm DL: Stathmin expression and its relationship to microtubule-associated protein tau and outcome in breast cancer. Cancer. 2012 Oct 1; 2012 Feb 22. PMID: 22359235

Davis MJ, Schlessinger J: The genesis of Zelboraf: targeting mutant B-Raf in melanoma. J Cell Biol. 2012 Oct 1. PMID: 23027900

Hanna JA, Hahn L, Agarwal S, Rimm DL: In situ measurement of miR-205 in malignant melanoma tissue supports its role as a tumor suppressor microRNA. Lab Invest. 2012 Oct; 2012 Aug 13. PMID: 22890556

Shields SD, Ahn HS, Yang Y, Han C, Seal RP, Wood JN, Waxman SG, Dib-Hajj SD: Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system. Pain. 2012 Oct; 2012 Jun 15. PMID: 22703890

Stiegler AL, Draheim KM, Li X, Chayen NE, Calderwood DA, Boggon TJ: Structural basis for paxillin binding and focal adhesion targeting of β-parvin. J Biol Chem. 2012 Sep 21; 2012 Aug 6. PMID: 22869380

Horsley V: Split decisions: oesophageal progenitor cell behaviour. EMBO J. 2012 Sep 12; 2012 Aug 10. PMID: 22885597

Brahme NN, Calderwood DA: Cell adhesion: a FERM grasp of the tail sorts out integrins. Curr Biol. 2012 Sep 11. PMID: 22974999

Ji W, Li Y, Wan T, Wang J, Zhang H, Chen H, Min W: Both internalization and AIP1 association are required for tumor necrosis factor receptor 2-mediated JNK signaling. Arterioscler Thromb Vasc Biol. 2012 Sep; 2012 Jun 28. PMID: 22743059

Fodeh SJ, Haddad A, Brandt C, Schultz M, Krauthammer M: Enhancing Clustering by Exploiting Complementary Data Modalities in the Medical Domain. IFIP Adv Inf Commun Technol. 2012 Sep. PMID: 29479376

Wysolmerski JJ: Parathyroid hormone-related protein: an update. J Clin Endocrinol Metab. 2012 Sep; 2012 Jun 28. PMID: 22745236

Krauthammer M, Kong Y, Ha BH, Evans P, Bacchiocchi A, McCusker JP, Cheng E, Davis MJ, Goh G, Choi M, Ariyan S, Narayan D, Dutton-Regester K, Capatana A, Holman EC, Bosenberg M, Sznol M, Kluger HM, Brash DE, Stern DF, Materin MA, Lo RS, Mane S, Ma S, Kidd KK, Hayward NK, Lifton RP, Schlessinger J, Boggon TJ, Halaban R: Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet. 2012 Sep; 2012 Jul 29. PMID: 22842228

Idevall-Hagren O, Dickson EJ, Hille B, Toomre DK, De Camilli P: Optogenetic control of phosphoinositide metabolism. Proc Natl Acad Sci U S A. 2012 Aug 28; 2012 Jul 30. PMID: 22847441

MacGrath SM, Koleske AJ: Arg/Abl2 modulates the affinity and stoichiometry of binding of cortactin to F-actin. Biochemistry. 2012 Aug 21; 2012 Aug 10. PMID: 22849492

Baldassarre M, Razinia Z, Brahme NN, Buccione R, Calderwood DA: Filamin A controls matrix metalloproteinase activity and regulates cell invasion in human fibrosarcoma cells. J Cell Sci. 2012 Aug 15; 2012 May 17. PMID: 22595522

Ruan HB, Han X, Li MD, Singh JP, Qian K, Azarhoush S, Zhao L, Bennett AM, Samuel VT, Wu J, Yates JR 3rd, Yang X: O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability. Cell Metab. 2012 Aug 8. PMID: 22883232

Goldstein J, Horsley V: Home sweet home: skin stem cell niches. Cell Mol Life Sci. 2012 Aug; 2012 Mar 13. PMID: 22410738

Desir GV, Tang L, Wang P, Li G, Sampaio-Maia B, Quelhas-Santos J, Pestana M, Velazquez H: Renalase lowers ambulatory blood pressure by metabolizing circulating adrenaline. J Am Heart Assoc. 2012 Aug; 2012 Aug 24. PMID: 23130169

Wetzel DM, McMahon-Pratt D, Koleske AJ: The Abl and Arg kinases mediate distinct modes of phagocytosis and are required for maximal Leishmania infection. Mol Cell Biol. 2012 Aug; 2012 Jun 4. PMID: 22665498

Bannwarth L, Goldberg AB, Chen C, Turk BE: Identification of exosite-targeting inhibitors of anthrax lethal factor by high-throughput screening. Chem Biol. 2012 Jul 27. PMID: 22840775

Rompolas P, Deschene ER, Zito G, Gonzalez DG, Saotome I, Haberman AM, Greco V: Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration. Nature. 2012 Jul 26. PMID: 22763436

Feng C, Neumeister V, Ma W, Xu J, Lu L, Bordeaux J, Maihle NJ, Rimm DL, Huang Y: Lin28 regulates HER2 and promotes malignancy through multiple mechanisms. Cell Cycle. 2012 Jul 1; 2012 Jul 1. PMID: 22713243

Yao GQ, Wu JJ, Troiano N, Zhu ML, Xiao XY, Insogna K: Selective deletion of the membrane-bound colony stimulating factor 1 isoform leads to high bone mass but does not protect against estrogen-deficiency bone loss. J Bone Miner Metab. 2012 Jul; 2011 Nov 23. PMID: 22105655

Li X, Zhang R, Draheim KM, Liu W, Calderwood DA, Boggon TJ: Structural basis for small G protein effector interaction of Ras-related protein 1 (Rap1) and adaptor protein Krev interaction trapped 1 (KRIT1). J Biol Chem. 2012 Jun 22; 2012 May 10. PMID: 22577140

Lee SK, Kim GS, Wu Y, Kim DJ, Lu Y, Kwak M, Han L, Hyung JH, Seol JK, Sander C, Gonzalez A, Li J, Fan R: Nanowire substrate-based laser scanning cytometry for quantitation of circulating tumor cells. Nano Lett. 2012 Jun 13; 2012 May 31. PMID: 22646476

Rubenstein EM, Kreft SG, Greenblatt W, Swanson R, Hochstrasser M: Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase. J Cell Biol. 2012 Jun 11. PMID: 22689655

Ćelić AS, Petri ET, Benbow J, Hodsdon ME, Ehrlich BE, Boggon TJ: Calcium-induced conformational changes in C-terminal tail of polycystin-2 are necessary for channel gating. J Biol Chem. 2012 May 18; 2012 Apr 3. PMID: 22474326

Marin EP, Derakhshan B, Lam TT, Davalos A, Sessa WC: Endothelial cell palmitoylproteomic identifies novel lipid-modified targets and potential substrates for protein acyl transferases. Circ Res. 2012 May 11; 2012 Apr 10. PMID: 22496122

Mertz AF, Banerjee S, Che Y, German GK, Xu Y, Hyland C, Marchetti MC, Horsley V, Dufresne ER: Scaling of traction forces with the size of cohesive cell colonies. Phys Rev Lett. 2012 May 11; 2012 May 8. PMID: 23003091

Shieh FK, Drumm H, Nathanson MH, Jamidar PA: High-definition confocal endomicroscopy of the common bile duct. J Clin Gastroenterol. 2012 May-Jun. PMID: 22011583

Desir G: Novel insights into the physiology of renalase and its role in hypertension and heart disease. Pediatr Nephrol. 2012 May; 2011 Mar 20. PMID: 21424526

Boras-Granic K, Wysolmerski JJ: PTHrP and breast cancer: more than hypercalcemia and bone metastases. Breast Cancer Res. 2012 Apr 25; 2012 Apr 25. PMID: 22546075

Li MD, Ruan HB, Singh JP, Zhao L, Zhao T, Azarhoush S, Wu J, Evans RM, Yang X: O-GlcNAc transferase is involved in glucocorticoid receptor-mediated transrepression. J Biol Chem. 2012 Apr 13; 2012 Feb 27. PMID: 22371499

Frey MA, Michaud M, VanHouten JN, Insogna KL, Madri JA, Barrett SE: Phosphorus-31 MRI of hard and soft solids using quadratic echo line-narrowing. Proc Natl Acad Sci U S A. 2012 Apr 3; 2012 Mar 19. PMID: 22431609

Gillies J, Hochstrasser M: A new class of SUMO proteases. EMBO Rep. 2012 Apr 2; 2012 Apr 2. PMID: 22422001

Truman LA, Bentley KL, Smith EC, Massaro SA, Gonzalez DG, Haberman AM, Hill M, Jones D, Min W, Krause DS, Ruddle NH: ProxTom lymphatic vessel reporter mice reveal Prox1 expression in the adrenal medulla, megakaryocytes, and platelets. Am J Pathol. 2012 Apr; 2012 Feb 4. PMID: 22310467

Hanna JA, Wimberly H, Kumar S, Slack F, Agarwal S, Rimm DL: Quantitative analysis of microRNAs in tissue microarrays by in situ hybridization. Biotechniques. 2012 Apr. PMID: 22482439

MacGrath SM, Koleske AJ: Cortactin in cell migration and cancer at a glance. J Cell Sci. 2012 Apr 1. PMID: 22566665

Sousa LP, Lax I, Shen H, Ferguson SM, De Camilli P, Schlessinger J: Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane. Proc Natl Acad Sci U S A. 2012 Mar 20; 2012 Feb 27. PMID: 22371560

Anagnostou VK, Dimou AT, Botsis T, Killiam EJ, Gustavson MD, Homer RJ, Boffa D, Zolota V, Dougenis D, Tanoue L, Gettinger SN, Detterbeck FC, Syrigos KN, Bepler G, Rimm DL: Molecular classification of nonsmall cell lung cancer using a 4-protein quantitative assay. Cancer. 2012 Mar 15; 2011 Aug 25. PMID: 22009766

Politi K, Lynch TJ: Two sides of the same coin: EGFR exon 19 deletions and insertions in lung cancer. Clin Cancer Res. 2012 Mar 15; 2012 Feb 8. PMID: 22317760

Bouaouina M, Goult BT, Huet-Calderwood C, Bate N, Brahme NN, Barsukov IL, Critchley DR, Calderwood DA: A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbβ3 integrin coactivation. J Biol Chem. 2012 Mar 2; 2012 Jan 10. PMID: 22235127

Jones D, Li Y, He Y, Xu Z, Chen H, Min W: Mirtron microRNA-1236 inhibits VEGFR-3 signaling during inflammatory lymphangiogenesis. Arterioscler Thromb Vasc Biol. 2012 Mar; 2012 Jan 5. PMID: 22223733

Kopic S, Wagner ME, Griessenauer C, Socrates T, Ritter M, Geibel JP: Vacuolar-type H+-ATPase-mediated proton transport in the rat parietal cell. Pflugers Arch. 2012 Mar; 2011 Nov 17. PMID: 22146938

Warren MS, Bradley WD, Gourley SL, Lin YC, Simpson MA, Reichardt LF, Greer CA, Taylor JR, Koleske AJ: Integrin β1 signals through Arg to regulate postnatal dendritic arborization, synapse density, and behavior. J Neurosci. 2012 Feb 22. PMID: 22357865

Schwartz MA, Simons M: Lymphatics thrive on stress: mechanical force in lymphatic development. EMBO J. 2012 Feb 15; 2012 Feb 15. PMID: 22334045

Gourley SL, Olevska A, Warren MS, Taylor JR, Koleske AJ: Arg kinase regulates prefrontal dendritic spine refinement and cocaine-induced plasticity. J Neurosci. 2012 Feb 15. PMID: 22396406

Liu W, MacGrath SM, Koleske AJ, Boggon TJ: Lysozyme contamination facilitates crystallization of a heterotrimeric cortactin-Arg-lysozyme complex. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1; 2012 Jan 25. PMID: 22297987

Agarwal S, Rimm DL: Making every cell like HeLa a giant step for cell culture. Am J Pathol. 2012 Feb; 2011 Dec 20. PMID: 22192626

Holmberg JC, Haddad S, Wünsche V, Yang Y, Aldo PB, Gnainsky Y, Granot I, Dekel N, Mor G: An in vitro model for the study of human implantation. Am J Reprod Immunol. 2012 Feb; 2011 Dec 12. PMID: 22151560

Wu Y, Lu Y, Chen W, Fu J, Fan R: In silico experimentation of glioma microenvironment development and anti-tumor therapy. PLoS Comput Biol. 2012 Feb; 2012 Feb 2. PMID: 22319429

Arasaki K, Toomre DK, Roy CR: The Legionella pneumophila effector DrrA is sufficient to stimulate SNARE-dependent membrane fusion. Cell Host Microbe. 2012 Jan 19. PMID: 22264512

Arena EA, Longo WE, Roberts KE, Geibel P, Nateqi J, Brandstetter M, Geibel JP: Functional role of NHE4 as a pH regulator in rat and human colonic crypts. Am J Physiol Cell Physiol. 2012 Jan 15; 2011 Nov 2. PMID: 22049213

Kuhn T, Luong T, Krauthammer M: Finding and accessing diagrams in biomedical publications. AMIA Annu Symp Proc. 2012; 2012 Nov 3. PMID: 23304318

Razinia Z, Mäkelä T, Ylänne J, Calderwood DA: Filamins in mechanosensing and signaling. Annu Rev Biophys. 2012; 2012 Feb 23. PMID: 22404683

Welsh AW, Lannin DR, Young GS, Sherman ME, Figueroa JD, Henry NL, Ryden L, Kim C, Love RR, Schiff R, Rimm DL: Cytoplasmic estrogen receptor in breast cancer. Clin Cancer Res. 2012 Jan 1; 2011 Oct 6. PMID: 21980134

Hochstrasser M, Funakoshi M: Disulfide engineering to map subunit interactions in the proteasome and other macromolecular complexes. Methods Mol Biol. 2012. PMID: 22350897

Bouaouina M, Harburger DS, Calderwood DA: Talin and signaling through integrins. Methods Mol Biol. 2012. PMID: 21909921

Felberbaum R, Wilson NR, Cheng D, Peng J, Hochstrasser M: Desumoylation of the endoplasmic reticulum membrane VAP family protein Scs2 by Ulp1 and SUMO regulation of the inositol synthesis pathway. Mol Cell Biol. 2012 Jan; 2011 Oct 24. PMID: 22025676

Yang Y, Dib-Hajj SD, Zhang J, Zhang Y, Tyrrell L, Estacion M, Waxman SG: Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Na(V)1.7 mutant channel. Nat Commun. 2012. PMID: 23149731

Anderson C, Zhou S, Sawin E, Horvitz HR, Hurwitz ME: SLI-1 Cbl inhibits the engulfment of apoptotic cells in C. elegans through a ligase-independent function. PLoS Genet. 2012; 2012 Dec 13. PMID: 23271977

Bordeaux JM, Cheng H, Welsh AW, Haffty BG, Lannin DR, Wu X, Su N, Ma XJ, Luo Y, Rimm DL: Quantitative in situ measurement of estrogen receptor mRNA predicts response to tamoxifen. PLoS One. 2012; 2012 May 11. PMID: 22606272

Zito CR, Jilaveanu LB, Anagnostou V, Rimm D, Bepler G, Maira SM, Hackl W, Camp R, Kluger HM, Chao HH: Multi-level targeting of the phosphatidylinositol-3-kinase pathway in non-small cell lung cancer cells. PLoS One. 2012; 2012 Feb 15. PMID: 22355357

Tomko RJ Jr, Hochstrasser M: Incorporation of the Rpn12 subunit couples completion of proteasome regulatory particle lid assembly to lid-base joining. Mol Cell. 2011 Dec 23. PMID: 22195964

Damsky WE, Curley DP, Santhanakrishnan M, Rosenbaum LE, Platt JT, Gould Rothberg BE, Taketo MM, Dankort D, Rimm DL, McMahon M, Bosenberg M: β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas. Cancer Cell. 2011 Dec 13. PMID: 22172720

Jamison RA, Stark R, Dong J, Yonemitsu S, Zhang D, Shulman GI, Kibbey RG: Hyperglucagonemia precedes a decline in insulin secretion and causes hyperglycemia in chronically glucose-infused rats. Am J Physiol Endocrinol Metab. 2011 Dec; 2011 Aug 23. PMID: 21862723

Xu Y, Melia TJ, Toomre DK: Using light to see and control membrane traffic. Curr Opin Chem Biol. 2011 Dec; 2011 Nov 10. PMID: 22079055

Stankewich MC, Cianci CD, Stabach PR, Ji L, Nath A, Morrow JS: Cell organization, growth, and neural and cardiac development require αII-spectrin. J Cell Sci. 2011 Dec 1; 2011 Dec 8. PMID: 22159418

Rimm DL: C-path: a Watson-like visit to the pathology lab. Sci Transl Med. 2011 Nov 9. PMID: 22072635

Baquero MT, Lostritto K, Gustavson MD, Bassi KA, Appia F, Camp RL, Molinaro AM, Harris LN, Rimm DL: Evaluation of prognostic and predictive value of microtubule associated protein tau in two independent cohorts. Breast Cancer Res. 2011 Nov 2; 2011 Nov 2. PMID: 21888627

Kruglov EA, Gautam S, Guerra MT, Nathanson MH: Type 2 inositol 1,4,5-trisphosphate receptor modulates bile salt export pump activity in rat hepatocytes. Hepatology. 2011 Nov; 2011 Aug 30. PMID: 21748767

Kim KH, Toomre D, Bender JR: Splice isoform estrogen receptors as integral transmembrane proteins. Mol Biol Cell. 2011 Nov; 2011 Sep 21. PMID: 21937726

Shenoy A, Kopic S, Murek M, Caputo C, Geibel JP, Egan ME: Calcium-modulated chloride pathways contribute to chloride flux in murine cystic fibrosis-affected macrophages. Pediatr Res. 2011 Nov. PMID: 21796019

Lizardi PM, Forloni M, Wajapeyee N: Genome-wide approaches for cancer gene discovery. Trends Biotechnol. 2011 Nov; 2011 Jul 13. PMID: 21757246

Min W, Pober JS: AIP1 in graft arteriosclerosis. Trends Cardiovasc Med. 2011 Nov. PMID: 22902071

Guan W, Fan R, Reed MA: Field-effect reconfigurable nanofluidic ionic diodes. Nat Commun. 2011 Oct 18; 2011 Oct 18. PMID: 22009038

Chagpar AB, Camp RL, Rimm DL: Lymph node ratio should be considered for incorporation into staging for breast cancer. Ann Surg Oncol. 2011 Oct; 2011 Aug 17. PMID: 21847696

Cooper MA, Koleske AJ: ErbB4 localization to interneurons: clearer insights into schizophrenia pathology. Biol Psychiatry. 2011 Oct 1. PMID: 21924131

Cao PD, Cheung WK, Nguyen DX: Cell lineage specification in tumor progression and metastasis. Discov Med. 2011 Oct. PMID: 22031670

Schulman-Green D, Bradley EH, Knobf MT, Prigerson H, DiGiovanna MP, McCorkle R: Self-management and transitions in women with advanced breast cancer. J Pain Symptom Manage. 2011 Oct; 2011 Mar 27. PMID: 21444183

Chen H, He H, Zou Y, Chen W, Yu R, Liu X, Yang Y, Gao YM, Xu JL, Fan LM, Li Y, Li ZK, Deng XW: Development and application of a set of breeder-friendly SNP markers for genetic analyses and molecular breeding of rice (Oryza sativa L.). Theor Appl Genet. 2011 Oct; 2011 Jun 18. PMID: 21681488

Xie P, Kranzler HR, Krauthammer M, Cosgrove KP, Oslin D, Anton RF, Farrer LA, Picciotto MR, Krystal JH, Zhao H, Gelernter J: Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biol Psychiatry. 2011 Sep 15; 2011 Jun 17. PMID: 21683344

Festa E, Fretz J, Berry R, Schmidt B, Rodeheffer M, Horowitz M, Horsley V: Adipocyte lineage cells contribute to the skin stem cell niche to drive hair cycling. Cell. 2011 Sep 2. PMID: 21884937

Andrade V, Guerra M, Jardim C, Melo F, Silva W, Ortega JM, Robert M, Nathanson MH, Leite F: Nucleoplasmic calcium regulates cell proliferation through legumain. J Hepatol. 2011 Sep; 2011 Jan 13. PMID: 21237226

Diano S, Liu ZW, Jeong JK, Dietrich MO, Ruan HB, Kim E, Suyama S, Kelly K, Gyengesi E, Arbiser JL, Belsham DD, Sarruf DA, Schwartz MW, Bennett AM, Shanabrough M, Mobbs CV, Yang X, Gao XB, Horvath TL: Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity. Nat Med. 2011 Aug 28; 2011 Aug 28. PMID: 21873987

Rabøl R, Petersen KF, Dufour S, Flannery C, Shulman GI: Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals. Proc Natl Acad Sci U S A. 2011 Aug 16; 2011 Aug 1. PMID: 21808028

Yip KY, Utz L, Sitwell S, Hu X, Sidhu SS, Turk BE, Gerstein M, Kim PM: Identification of specificity determining residues in peptide recognition domains using an information theoretic approach applied to large-scale binding maps. BMC Biol. 2011 Aug 11; 2011 Aug 11. PMID: 21835011

Yu L, Qin L, Zhang H, He Y, Chen H, Pober JS, Tellides G, Min W: AIP1 prevents graft arteriosclerosis by inhibiting interferon-γ-dependent smooth muscle cell proliferation and intimal expansion. Circ Res. 2011 Aug 5; 2011 Jun 23. PMID: 21700930

Horsley V: Upward bound: follicular stem cell fate decisions. EMBO J. 2011 Aug 3; 2011 Aug 3. PMID: 21811300

Dimou A, Agarwal S, Anagnostou V, Viray H, Christensen S, Gould Rothberg B, Zolota V, Syrigos K, Rimm DL: Standardization of epidermal growth factor receptor (EGFR) measurement by quantitative immunofluorescence and impact on antibody-based mutation detection in non-small cell lung cancer. Am J Pathol. 2011 Aug; 2011 Jun 12. PMID: 21722621

Yang Q, Karpikov A, Toomre D, Duncan JS: 3-D reconstruction of microtubules from multi-angle total internal reflection fluorescence microscopy using Bayesian framework. IEEE Trans Image Process. 2011 Aug; 2011 Feb 14. PMID: 21324778

Razinia Z, Baldassarre M, Bouaouina M, Lamsoul I, Lutz PG, Calderwood DA: The E3 ubiquitin ligase specificity subunit ASB2α targets filamins for proteasomal degradation by interacting with the filamin actin-binding domain. J Cell Sci. 2011 Aug 1; 2011 Jul 12. PMID: 21750192

Welsh AW, Moeder CB, Kumar S, Gershkovich P, Alarid ET, Harigopal M, Haffty BG, Rimm DL: Standardization of estrogen receptor measurement in breast cancer suggests false-negative results are a function of threshold intensity rather than percentage of positive cells. J Clin Oncol. 2011 Aug 1; 2011 Jun 27. PMID: 21709197

Bai Y, Tolles J, Cheng H, Siddiqui S, Gopinath A, Pectasides E, Camp RL, Rimm DL, Molinaro AM: Quantitative assessment shows loss of antigenic epitopes as a function of pre-analytic variables. Lab Invest. 2011 Aug; 2011 Apr 25. PMID: 21519325

Wang M, Gamo NJ, Yang Y, Jin LE, Wang XJ, Laubach M, Mazer JA, Lee D, Arnsten AF: Neuronal basis of age-related working memory decline. Nature. 2011 Jul 27; 2011 Jul 27. PMID: 21796118

Li X, Ji W, Zhang R, Folta-Stogniew E, Min W, Boggon TJ: Molecular recognition of leucine-aspartate repeat (LD) motifs by the focal adhesion targeting homology domain of cerebral cavernous malformation 3 (CCM3). J Biol Chem. 2011 Jul 22; 2011 Jun 1. PMID: 21632544

Carpenter TO, Imel EA, Holm IA, Jan de Beur SM, Insogna KL: A clinician's guide to X-linked hypophosphatemia. J Bone Miner Res. 2011 Jul; 2011 May 2. PMID: 21538511

Flach RJ, Qin H, Zhang L, Bennett AM: Loss of mitogen-activated protein kinase phosphatase-1 protects from hepatic steatosis by repression of cell death-inducing DNA fragmentation factor A (DFFA)-like effector C (CIDEC)/fat-specific protein 27. J Biol Chem. 2011 Jun 24; 2011 Apr 26. PMID: 21521693

Rabbani P, Takeo M, Chou W, Myung P, Bosenberg M, Chin L, Taketo MM, Ito M: Coordinated activation of Wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration. Cell. 2011 Jun 10. PMID: 21663796

Kreft SG, Hochstrasser M: An unusual transmembrane helix in the endoplasmic reticulum ubiquitin ligase Doa10 modulates degradation of its cognate E2 enzyme. J Biol Chem. 2011 Jun 10; 2011 Apr 5. PMID: 21467040

Tomko RJ Jr, Hochstrasser M: Order of the proteasomal ATPases and eukaryotic proteasome assembly. Cell Biochem Biophys. 2011 Jun. PMID: 21461838

Chan E, Patel R, Nallur S, Ratner E, Bacchiocchi A, Hoyt K, Szpakowski S, Godshalk S, Ariyan S, Sznol M, Halaban R, Krauthammer M, Tuck D, Slack FJ, Weidhaas JB: MicroRNA signatures differentiate melanoma subtypes. Cell Cycle. 2011 Jun 1; 2011 Jun 1. PMID: 21543894

Rimm DL, Nielsen TO, Jewell SD, Rohrer DC, Broadwater G, Waldman F, Mitchell KA, Singh B, Tsongalis GJ, Frankel WL, Magliocco AM, Lara JF, Hsi ED, Bleiweiss IJ, Badve SS, Chen B, Ravdin PM, Schilsky RL, Thor A, Berry DA, Cancer and Leukemia Group B Pathology Committee.: Cancer and Leukemia Group B Pathology Committee guidelines for tissue microarray construction representing multicenter prospective clinical trial tissues. J Clin Oncol. 2011 Jun 1; 2011 Apr 25. PMID: 21519016

Politi K, Pao W: How genetically engineered mouse tumor models provide insights into human cancers. J Clin Oncol. 2011 Jun 1; 2011 Jan 24. PMID: 21263096

Wilson KA, Colavito SA, Schulz V, Wakefield PH, Sessa W, Tuck D, Stern DF: NFBD1/MDC1 regulates Cav1 and Cav2 independently of DNA damage and p53. Mol Cancer Res. 2011 Jun; 2011 May 6. PMID: 21551225

Tworkoski K, Singhal G, Szpakowski S, Zito CI, Bacchiocchi A, Muthusamy V, Bosenberg M, Krauthammer M, Halaban R, Stern DF: Phosphoproteomic screen identifies potential therapeutic targets in melanoma. Mol Cancer Res. 2011 Jun; 2011 Apr 26. PMID: 21521745

Stern DF: "Competence" progress. Mol Cell. 2011 May 20. PMID: 21596307

Tolles J, Bai Y, Baquero M, Harris LN, Rimm DL, Molinaro AM: Optimal tumor sampling for immunostaining of biomarkers in breast carcinoma. Breast Cancer Res. 2011 May 18; 2011 May 18. PMID: 21592345

Xu Y, Rubin BR, Orme CM, Karpikov A, Yu C, Bogan JS, Toomre DK: Dual-mode of insulin action controls GLUT4 vesicle exocytosis. J Cell Biol. 2011 May 16; 2011 May 9. PMID: 21555461

Pectasides E, Rampias T, Kountourakis P, Sasaki C, Kowalski D, Fountzilas G, Zaramboukas T, Rimm D, Burtness B, Psyrri A: Comparative prognostic value of epidermal growth factor quantitative protein expression compared with FISH for head and neck squamous cell carcinoma. Clin Cancer Res. 2011 May 1; 2011 Feb 25. PMID: 21355076

Chung C, Mader CC, Schmitz JC, Atladottir J, Fitchev P, Cornwell ML, Koleske AJ, Crawford SE, Gorelick F: The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer. Lab Invest. 2011 May; 2011 Feb 21. PMID: 21339745

Kusmierczyk AR, Kunjappu MJ, Kim RY, Hochstrasser M: A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor binding. Nat Struct Mol Biol. 2011 May; 2011 Apr 17. PMID: 21499243

Ekkati AR, Madiyan V, Ravindranathan KP, H Bae J, Schlessinger J, Jorgensen WL: Aryl Extensions of Thienopyrimidinones as Fibroblast Growth Factor Receptor 1 Kinase Inhibitors. Tetrahedron Lett. 2011 Apr 27. PMID: 21516197

MacGrath SM, Koleske AJ: Invadopodia: RhoC runs rings around cofilin. Curr Biol. 2011 Apr 26. PMID: 21514509

Bordner KA, George ED, Carlyle BC, Duque A, Kitchen RR, Lam TT, Colangelo CM, Stone KL, Abbott TB, Mane SM, Nairn AC, Simen AA: Functional genomic and proteomic analysis reveals disruption of myelin-related genes and translation in a mouse model of early life neglect. Front Psychiatry. 2011; 2011 Apr 25. PMID: 21629843

Albinsson S, Skoura A, Yu J, DiLorenzo A, Fernández-Hernando C, Offermanns S, Miano JM, Sessa WC: Smooth muscle miRNAs are critical for post-natal regulation of blood pressure and vascular function. PLoS One. 2011 Apr 22; 2011 Apr 22. PMID: 21526127

Mor G, Yin G, Chefetz I, Yang Y, Alvero A: Ovarian cancer stem cells and inflammation. Cancer Biol Ther. 2011 Apr 15; 2011 Apr 15. PMID: 21317559

Verma A, Degrado J, Hittelman AB, Wheeler MA, Kaimakliotis HZ, Weiss RM: Effect of mitomycin C on concentrations of vascular endothelial growth factor and its receptors in bladder cancer cells and in bladders of rats intravesically instilled with mitomycin C. BJU Int. 2011 Apr; 2010 Aug 24. PMID: 20735383

Alicea-Velázquez NL, Boggon TJ: The use of structural biology in Janus kinase targeted drug discovery. Curr Drug Targets. 2011 Apr. PMID: 21126226

Alves TC, Befroy DE, Kibbey RG, Kahn M, Codella R, Carvalho RA, Falk Petersen K, Shulman GI: Regulation of hepatic fat and glucose oxidation in rats with lipid-induced hepatic insulin resistance. Hepatology. 2011 Apr; 2011 Mar 11. PMID: 21400553

Wu Y, Xu J, Velazquez H, Wang P, Li G, Liu D, Sampaio-Maia B, Quelhas-Santos J, Russell K, Russell R, Flavell RA, Pestana M, Giordano F, Desir GV: Renalase deficiency aggravates ischemic myocardial damage. Kidney Int. 2011 Apr; 2010 Dec 22. PMID: 21178975

Ye ZJ, Gulcicek E, Stone K, Lam T, Schulz V, Weissman SM: Complex interactions in EML cell stimulation by stem cell factor and IL-3. Proc Natl Acad Sci U S A. 2011 Mar 22; 2011 Mar 7. PMID: 21383156

Mader CC, Oser M, Magalhaes MA, Bravo-Cordero JJ, Condeelis J, Koleske AJ, Gil-Henn H: An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion. Cancer Res. 2011 Mar 1; 2011 Jan 21. PMID: 21257711

Jurczak MJ, Lee HY, Birkenfeld AL, Jornayvaz FR, Frederick DW, Pongratz RL, Zhao X, Moeckel GW, Samuel VT, Whaley JM, Shulman GI, Kibbey RG: SGLT2 deletion improves glucose homeostasis and preserves pancreatic beta-cell function. Diabetes. 2011 Mar. PMID: 21357472

Akirav EM, Baquero MT, Opare-Addo LW, Akirav M, Galvan E, Kushner JA, Rimm DL, Herold KC: Glucose and inflammation control islet vascular density and beta-cell function in NOD mice: control of islet vasculature and vascular endothelial growth factor by glucose. Diabetes. 2011 Mar; 2011 Feb 9. PMID: 21307078

Yao GQ, Wu JJ, Troiano N, Insogna K: Targeted overexpression of Dkk1 in osteoblasts reduces bone mass but does not impair the anabolic response to intermittent PTH treatment in mice. J Bone Miner Metab. 2011 Mar; 2010 Jul 3. PMID: 20602130

Loeser CS, Robert ME, Mennone A, Nathanson MH, Jamidar P: Confocal endomicroscopic examination of malignant biliary strictures and histologic correlation with lymphatics. J Clin Gastroenterol. 2011 Mar. PMID: 21063210

Louvi A, Chen L, Two AM, Zhang H, Min W, Günel M: Loss of cerebral cavernous malformation 3 (Ccm3) in neuroglia leads to CCM and vascular pathology. Proc Natl Acad Sci U S A. 2011 Mar 1; 2011 Feb 14. PMID: 21321212

Shen H, Ferguson SM, Dephoure N, Park R, Yang Y, Volpicelli-Daley L, Gygi S, Schlessinger J, De Camilli P: Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin. Mol Biol Cell. 2011 Feb 15; 2010 Dec 17. PMID: 21169560

Bouaouina M, Calderwood DA: Kindlins. Curr Biol. 2011 Feb 8. PMID: 21300280

Garla V, Kong Y, Szpakowski S, Krauthammer M: MU2A--reconciling the genome and transcriptome to determine the effects of base substitutions. Bioinformatics. 2011 Feb 1; 2010 Dec 12. PMID: 21149339

Mennone A, Nathanson MH: Needle-based confocal laser endomicroscopy to assess liver histology in vivo. Gastrointest Endosc. 2011 Feb; 2010 Dec 8. PMID: 21145055

Reed AM, Husain SZ, Thrower E, Alexandre M, Shah A, Gorelick FS, Nathanson MH: Low extracellular pH induces damage in the pancreatic acinar cell by enhancing calcium signaling. J Biol Chem. 2011 Jan 21; 2010 Nov 17. PMID: 21084290

Kirchhoff P, Socrates T, Sidani S, Duffy A, Breidthardt T, Grob C, Viehl CT, Beglinger C, Oertli D, Geibel JP: Zinc salts provide a novel, prolonged and rapid inhibition of gastric acid secretion. Am J Gastroenterol. 2011 Jan; 2010 Aug 24. PMID: 20736941

Evans P, Krauthammer M: Exploring the use of social media to measure journal article impact. AMIA Annu Symp Proc. 2011; 2011 Oct 22. PMID: 22195090

Itokowa T, Zhu ML, Troiano N, Bian J, Kawano T, Insogna K: Osteoclasts lacking Rac2 have defective chemotaxis and resorptive activity. Calcif Tissue Int. 2011 Jan; 2010 Nov 26. PMID: 21110188

Wagner CA, Mohebbi N, Uhlig U, Giebisch GH, Breton S, Brown D, Geibel JP: Angiotensin II stimulates H⁺-ATPase activity in intercalated cells from isolated mouse connecting tubules and cortical collecting ducts. Cell Physiol Biochem. 2011; 2011 Nov 18. PMID: 22116365

Gourley SL, Taylor JR, Koleske AJ: Cell adhesion signaling pathways: First responders to cocaine exposure? Commun Integr Biol. 2011 Jan. PMID: 21509173

Desir GV: Role of renalase in the regulation of blood pressure and the renal dopamine system. Curr Opin Nephrol Hypertens. 2011 Jan. PMID: 21099685

Nguyen DX: Tracing the origins of metastasis. J Pathol. 2011 Jan; 2010 Oct 29. PMID: 21125675

Liang L, Shen H, De Camilli P, Toomre DK, Duncan JS: An expectation maximization based method for subcellular particle tracking using multi-angle TIRF microscopy. Med Image Comput Comput Assist Interv. 2011. PMID: 22003671

Fiedler MJ, Nathanson MH: The type I inositol 1,4,5-trisphosphate receptor interacts with protein 4.1N to mediate neurite formation through intracellular Ca waves. Neurosignals. 2011; 2011 Mar 10. PMID: 21389686

Boras-Granic K, VanHouten J, Hiremath M, Wysolmerski J: Parathyroid hormone-related protein is not required for normal ductal or alveolar development in the post-natal mammary gland. PLoS One. 2011; 2011 Nov 8. PMID: 22087279

Li MD, Yang X: A Retrospective on Nuclear Receptor Regulation of Inflammation: Lessons from GR and PPARs. PPAR Res. 2011; 2011 Sep 15. PMID: 21941526

Aziz SA, Jilaveanu LB, Zito C, Camp RL, Rimm DL, Conrad P, Kluger HM: Vertical targeting of the phosphatidylinositol-3 kinase pathway as a strategy for treating melanoma. Clin Cancer Res. 2010 Dec 15. PMID: 21169255

Jones D, Xu Z, Zhang H, He Y, Kluger MS, Chen H, Min W: Functional analyses of the bone marrow kinase in the X chromosome in vascular endothelial growth factor-induced lymphangiogenesis. Arterioscler Thromb Vasc Biol. 2010 Dec; 2010 Sep 23. PMID: 20864667

Kopic S, Geibel JP: Update on the mechanisms of gastric acid secretion. Curr Gastroenterol Rep. 2010 Dec. PMID: 20821079

Ardeshirpour L, Brian S, Dann P, VanHouten J, Wysolmerski J: Increased PTHrP and decreased estrogens alter bone turnover but do not reproduce the full effects of lactation on the skeleton. Endocrinology. 2010 Dec; 2010 Nov 3. PMID: 21047946

Roth Flach RJ, Bennett AM: Mitogen-activated protein kinase phosphatase-1 - a potential therapeutic target in metabolic disease. Expert Opin Ther Targets. 2010 Dec. PMID: 21058921

Fogel AI, Li Y, Giza J, Wang Q, Lam TT, Modis Y, Biederer T: N-glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion. J Biol Chem. 2010 Nov 5; 2010 Aug 25. PMID: 20739279

Rubenstein EM, Hochstrasser M: Redundancy and variation in the ubiquitin-mediated proteolytic targeting of a transcription factor. Cell Cycle. 2010 Nov 1; 2010 Nov 22. PMID: 20980825

Carpenter TO, Insogna KL, Zhang JH, Ellis B, Nieman S, Simpson C, Olear E, Gundberg CM: Circulating levels of soluble klotho and FGF23 in X-linked hypophosphatemia: circadian variance, effects of treatment, and relationship to parathyroid status. J Clin Endocrinol Metab. 2010 Nov; 2010 Aug 4. PMID: 20685863

Geibel JP: The calcium-sensing receptor. J Nephrol. 2010 Nov-Dec. PMID: 21170870

Gupta R, Nagarajan A, Wajapeyee N: Advances in genome-wide DNA methylation analysis. Biotechniques. 2010 Oct. PMID: 20964631

Peacock JG, Couch BA, Koleske AJ: The Abl and Arg non-receptor tyrosine kinases regulate different zones of stress fiber, focal adhesion, and contractile network localization in spreading fibroblasts. Cytoskeleton (Hoboken). 2010 Oct. PMID: 20737438

Muthusamy V, Bosenberg M, Wajapeyee N: Redefining regulation of DNA methylation by RNA interference. Genomics. 2010 Oct; 2010 Jul 8. PMID: 20620207

Gilmore-Hebert M, Ramabhadran R, Stern DF: Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways. Mol Cancer Res. 2010 Oct; 2010 Sep 21. PMID: 20858735

Dávalos A, Fernández-Hernando C, Sowa G, Derakhshan B, Lin MI, Lee JY, Zhao H, Luo R, Colangelo C, Sessa WC: Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells. Mol Cell Proteomics. 2010 Oct; 2010 Jun 28. PMID: 20585024

Letinic K, Sebastian R, Barthel A, Toomre D: Deciphering subcellular processes in live imaging datasets via dynamic probabilistic networks. Bioinformatics. 2010 Aug 15; 2010 Jun 26. PMID: 20581401

Nakatsu F, Perera RM, Lucast L, Zoncu R, Domin J, Gertler FB, Toomre D, De Camilli P: The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics. J Cell Biol. 2010 Aug 9; 2010 Aug 2. PMID: 20679431

Fernández-Hernando C, Yu J, Dávalos A, Prendergast J, Sessa WC: Endothelial-specific overexpression of caveolin-1 accelerates atherosclerosis in apolipoprotein E-deficient mice. Am J Pathol. 2010 Aug; 2010 Jun 25. PMID: 20581061

Neumeister V, Rimm D: Is ALDH1 a good method for definition of breast cancer stem cells? Breast Cancer Res Treat. 2010 Aug; 2009 Nov 28. PMID: 19946740

Shi H, Boadu E, Mercan F, Le AM, Flach RJ, Zhang L, Tyner KJ, Olwin BB, Bennett AM: MAP kinase phosphatase-1 deficiency impairs skeletal muscle regeneration and exacerbates muscular dystrophy. FASEB J. 2010 Aug; 2010 Apr 6. PMID: 20371627

Gould Rothberg BE, Rimm DL: Biomarkers: the useful and the not so useful--an assessment of molecular prognostic markers for cutaneous melanoma. J Invest Dermatol. 2010 Aug; 2010 Jun 17. PMID: 20555347

Su D, Hochstrasser M: A WLM protein with SUMO-directed protease activity. Mol Cell Biol. 2010 Aug; 2010 Jun 21. PMID: 20566698

Kopic S, Geibel JP: Toxin mediated diarrhea in the 21 century: the pathophysiology of intestinal ion transport in the course of ETEC, V. cholerae and rotavirus infection. Toxins (Basel). 2010 Aug; 2010 Aug 10. PMID: 22069677

Arnsten AF, Paspalas CD, Gamo NJ, Yang Y, Wang M: Dynamic Network Connectivity: A new form of neuroplasticity. Trends Cogn Sci. 2010 Aug; 2010 Jun 16. PMID: 20554470

Li X, Zhang R, Zhang H, He Y, Ji W, Min W, Boggon TJ: Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity. J Biol Chem. 2010 Jul 30; 2010 May 19. PMID: 20489202

Golan A, Pick E, Tsvetkov L, Nadler Y, Kluger H, Stern DF: Centrosomal Chk2 in DNA damage responses and cell cycle progression. Cell Cycle. 2010 Jul 1. PMID: 20581449

Mercan F, Bennett AM: Analysis of protein tyrosine phosphatases and substrates. Curr Protoc Mol Biol. 2010 Jul. PMID: 20583096

Chen C, Turk BE: Analysis of serine-threonine kinase specificity using arrayed positional scanning peptide libraries. Curr Protoc Mol Biol. 2010 Jul. PMID: 20583094

Cruz LN, Guerra MT, Kruglov E, Mennone A, Garcia CR, Chen J, Nathanson MH: Regulation of multidrug resistance-associated protein 2 by calcium signaling in mouse liver. Hepatology. 2010 Jul. PMID: 20578149

VanHouten J, Sullivan C, Bazinet C, Ryoo T, Camp R, Rimm DL, Chung G, Wysolmerski J: PMCA2 regulates apoptosis during mammary gland involution and predicts outcome in breast cancer. Proc Natl Acad Sci U S A. 2010 Jun 22; 2010 Jun 4. PMID: 20534448

Yu L, Ji W, Zhang H, Renda MJ, He Y, Lin S, Cheng EC, Chen H, Krause DS, Min W: SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis. J Exp Med. 2010 Jun 7; 2010 May 10. PMID: 20457756

Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC: MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun; 2010 Apr 8. PMID: 20378849

Petri ET, Celic A, Kennedy SD, Ehrlich BE, Boggon TJ, Hodsdon ME: Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity. Proc Natl Acad Sci U S A. 2010 May 18; 2010 May 3. PMID: 20439752

Tomko RJ Jr, Funakoshi M, Schneider K, Wang J, Hochstrasser M: Heterohexameric ring arrangement of the eukaryotic proteasomal ATPases: implications for proteasome structure and assembly. Mol Cell. 2010 May 14. PMID: 20471945

Lam HY, Kim PM, Mok J, Tonikian R, Sidhu SS, Turk BE, Snyder M, Gerstein MB: MOTIPS: automated motif analysis for predicting targets of modular protein domains. BMC Bioinformatics. 2010 May 11; 2010 May 11. PMID: 20459839

Anagnostou VK, Lowery FJ, Zolota V, Tzelepi V, Gopinath A, Liceaga C, Panagopoulos N, Frangia K, Tanoue L, Boffa D, Gettinger S, Detterbeck F, Homer RJ, Dougenis D, Rimm DL, Syrigos KN: High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology. BMC Cancer. 2010 May 9; 2010 May 9. PMID: 20459695

Neumeister V, Agarwal S, Bordeaux J, Camp RL, Rimm DL: In situ identification of putative cancer stem cells by multiplexing ALDH1, CD44, and cytokeratin identifies breast cancer patients with poor prognosis. Am J Pathol. 2010 May; 2010 Mar 12. PMID: 20228222

Greco V, Guo S: Compartmentalized organization: a common and required feature of stem cell niches? Development. 2010 May. PMID: 20430743

Xie Y, Rubenstein EM, Matt T, Hochstrasser M: SUMO-independent in vivo activity of a SUMO-targeted ubiquitin ligase toward a short-lived transcription factor. Genes Dev. 2010 May; 2010 Apr 13. PMID: 20388728

Foster HE Jr, Hanno PM, Nickel JC, Payne CK, Mayer RD, Burks DA, Yang CC, Chai TC, Kreder KJ, Peters KM, Lukacz ES, FitzGerald MP, Cen L, Landis JR, Propert KJ, Yang W, Kusek JW, Nyberg LM, Interstitial Cystitis Collaborative Research Network.: Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome. J Urol. 2010 May; 2010 Mar 29. PMID: 20303115

Bae JH, Schlessinger J: Asymmetric tyrosine kinase arrangements in activation or autophosphorylation of receptor tyrosine kinases. Mol Cells. 2010 May; 2010 Apr 28. PMID: 20432069

Pectasides E, Egloff AM, Sasaki C, Kountourakis P, Burtness B, Fountzilas G, Dafni U, Zaramboukas T, Rampias T, Rimm D, Grandis J, Psyrri A: Nuclear localization of signal transducer and activator of transcription 3 in head and neck squamous cell carcinoma is associated with a better prognosis. Clin Cancer Res. 2010 Apr 15; 2010 Apr 6. PMID: 20371693

Yang X: A wheel of time: the circadian clock, nuclear receptors, and physiology. Genes Dev. 2010 Apr 15. PMID: 20395363

Flach RJ, Bennett AM: MAP kinase phosphatase-1--a new player at the nexus between sarcopenia and metabolic disease. Aging (Albany NY). 2010 Apr 6; 2010 Apr 6. PMID: 20375469

He Y, Zhang H, Yu L, Gunel M, Boggon TJ, Chen H, Min W: Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development. Sci Signal. 2010 Apr 6; 2010 Apr 6. PMID: 20371769

Harigopal M, Barlow WE, Tedeschi G, Porter PL, Yeh IT, Haskell C, Livingston R, Hortobagyi GN, Sledge G, Shapiro C, Ingle JN, Rimm DL, Hayes DF: Multiplexed assessment of the Southwest Oncology Group-directed Intergroup Breast Cancer Trial S9313 by AQUA shows that both high and low levels of HER2 are associated with poor outcome. Am J Pathol. 2010 Apr; 2010 Feb 11. PMID: 20150438

Anagnostou VK, Lowery FJ, Syrigos KN, Cagle PT, Rimm DL: Quantitative evaluation of protein expression as a function of tissue microarray core diameter: is a large (1.5 mm) core better than a small (0.6 mm) core? Arch Pathol Lab Med. 2010 Apr. PMID: 20367312

Chakraborty AK, Welsh A, Digiovanna MP: Co-targeting the insulin-like growth factor I receptor enhances growth-inhibitory and pro-apoptotic effects of anti-estrogens in human breast cancer cell lines. Breast Cancer Res Treat. 2010 Apr; 2009 Apr 1. PMID: 19337828

Anagnostou VK, Welsh AW, Giltnane JM, Siddiqui S, Liceaga C, Gustavson M, Syrigos KN, Reiter JL, Rimm DL: Analytic variability in immunohistochemistry biomarker studies. Cancer Epidemiol Biomarkers Prev. 2010 Apr; 2010 Mar 23. PMID: 20332259

Murek M, Kopic S, Geibel J: Evidence for intestinal chloride secretion. Exp Physiol. 2010 Apr. PMID: 20233891

Chiswell BP, Stiegler AL, Razinia Z, Nalibotski E, Boggon TJ, Calderwood DA: Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase. J Struct Biol. 2010 Apr; 2009 Dec 4. PMID: 19963065

Halaban R, Zhang W, Bacchiocchi A, Cheng E, Parisi F, Ariyan S, Krauthammer M, McCusker JP, Kluger Y, Sznol M: PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells. Pigment Cell Melanoma Res. 2010 Apr; 2010 Feb 10. PMID: 20149136

Stankewich MC, Gwynn B, Ardito T, Ji L, Kim J, Robledo RF, Lux SE, Peters LL, Morrow JS: Targeted deletion of betaIII spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes. Proc Natl Acad Sci U S A. 2010 Mar 30; 2010 Mar 15. PMID: 20231455

Miller MM, Lapetina S, MacGrath SM, Sfakianos MK, Pollard TD, Koleske AJ: Regulation of actin polymerization and adhesion-dependent cell edge protrusion by the Abl-related gene (Arg) tyrosine kinase and N-WASp. Biochemistry. 2010 Mar 16. PMID: 20146487

Wysolmerski JJ: Interactions between breast, bone, and brain regulate mineral and skeletal metabolism during lactation. Ann N Y Acad Sci. 2010 Mar. PMID: 20392232

Bordeaux J, Welsh A, Agarwal S, Killiam E, Baquero M, Hanna J, Anagnostou V, Rimm D: Antibody validation. Biotechniques. 2010 Mar. PMID: 20359301

Gaffney-Stomberg E, Sun BH, Cucchi CE, Simpson CA, Gundberg C, Kerstetter JE, Insogna KL: The effect of dietary protein on intestinal calcium absorption in rats. Endocrinology. 2010 Mar; 2010 Feb 10. PMID: 20147526

Mehnert JM, McCarthy MM, Jilaveanu L, Flaherty KT, Aziz S, Camp RL, Rimm DL, Kluger HM: Quantitative expression of VEGF, VEGF-R1, VEGF-R2, and VEGF-R3 in melanoma tissue microarrays. Hum Pathol. 2010 Mar; 2009 Dec 11. PMID: 20004943

Mamillapalli R, Wysolmerski J: The calcium-sensing receptor couples to Galpha(s) and regulates PTHrP and ACTH secretion in pituitary cells. J Endocrinol. 2010 Mar; 2009 Dec 23. PMID: 20032198

Ravindranathan KP, Mandiyan V, Ekkati AR, Bae JH, Schlessinger J, Jorgensen WL: Discovery of novel fibroblast growth factor receptor 1 kinase inhibitors by structure-based virtual screening. J Med Chem. 2010 Feb 25. PMID: 20121196

Bae JH, Boggon TJ, Tomé F, Mandiyan V, Lax I, Schlessinger J: Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells. Proc Natl Acad Sci U S A. 2010 Feb 16; 2010 Jan 26. PMID: 20133753

Mok J, Kim PM, Lam HY, Piccirillo S, Zhou X, Jeschke GR, Sheridan DL, Parker SA, Desai V, Jwa M, Cameroni E, Niu H, Good M, Remenyi A, Ma JL, Sheu YJ, Sassi HE, Sopko R, Chan CS, De Virgilio C, Hollingsworth NM, Lim WA, Stern DF, Stillman B, Andrews BJ, Gerstein MB, Snyder M, Turk BE: Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs. Sci Signal. 2010 Feb 16; 2010 Feb 16. PMID: 20159853

Rubinstein JC, Tran N, Ma S, Halaban R, Krauthammer M: Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma. BMC Med Genomics. 2010 Feb 9; 2010 Feb 9. PMID: 20144234

Wan T, Liu T, Zhang H, Tang S, Min W: AIP1 functions as Arf6-GAP to negatively regulate TLR4 signaling. J Biol Chem. 2010 Feb 5; 2009 Nov 30. PMID: 19948740

Yang Y, Xie P, Opatowsky Y, Schlessinger J: Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling. Proc Natl Acad Sci U S A. 2010 Feb 2; 2010 Jan 11. PMID: 20080685

Yan Q, Wajapeyee N: Exploiting cellular senescence to treat cancer and circumvent drug resistance. Cancer Biol Ther. 2010 Feb; 2010 Feb 11. PMID: 20118655

Kopic S, Murek M, Geibel JP: Revisiting the parietal cell. Am J Physiol Cell Physiol. 2010 Jan; 2009 Nov 4. PMID: 19889964

Toomre D, Bewersdorf J: A new wave of cellular imaging. Annu Rev Cell Dev Biol. 2010. PMID: 20929313

Lin YC, Koleske AJ: Mechanisms of synapse and dendrite maintenance and their disruption in psychiatric and neurodegenerative disorders. Annu Rev Neurosci. 2010. PMID: 20367247

Koay DC, Zerillo C, Narayan M, Harris LN, DiGiovanna MP: Anti-tumor effects of retinoids combined with trastuzumab or tamoxifen in breast cancer cells: induction of apoptosis by retinoid/trastuzumab combinations. Breast Cancer Res. 2010; 2010 Aug 9. PMID: 20696059

Kopic S, Corradini S, Sidani S, Murek M, Vardanyan A, Föller M, Ritter M, Geibel JP: Ethanol inhibits gastric acid secretion in rats through increased AMP-kinase activity. Cell Physiol Biochem. 2010; 2010 Jan 12. PMID: 20110680

Couch BA, DeMarco GJ, Gourley SL, Koleske AJ: Increased dendrite branching in AbetaPP/PS1 mice and elongation of dendrite arbors by fasudil administration. J Alzheimers Dis. 2010. PMID: 20413901

Suárez Y, Wang C, Manes TD, Pober JS: Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation. J Immunol. 2010 Jan 1; 2009 Nov 30. PMID: 19949084

Yang Q, Karpikov A, Toomre D, Duncan J: Estimation of 3D geometry of microtubules using multi-angle total internal reflection fluorescence microscopy. Med Image Comput Comput Assist Interv. 2010. PMID: 20879357

Min W, Xu LK, Zhou HJ, Huang Q, Zhang H, He Y, Zhe X, Luo Y: Thioredoxin and redox signaling in vasculature-studies using Trx2 endothelium-specific transgenic mice. Methods Enzymol. 2010; 2010 Jun 20. PMID: 20609919

Fernández-Hernando C, József L, Jenkins D, Di Lorenzo A, Sessa WC: Absence of Akt1 reduces vascular smooth muscle cell migration and survival and induces features of plaque vulnerability and cardiac dysfunction during atherosclerosis. Arterioscler Thromb Vasc Biol. 2009 Dec; 2009 Sep 17. PMID: 19762778

Erion DM, Ignatova ID, Yonemitsu S, Nagai Y, Chatterjee P, Weismann D, Hsiao JJ, Zhang D, Iwasaki T, Stark R, Flannery C, Kahn M, Carmean CM, Yu XX, Murray SF, Bhanot S, Monia BP, Cline GW, Samuel VT, Shulman GI: Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein. Cell Metab. 2009 Dec. PMID: 19945407

Roth RJ, Le AM, Zhang L, Kahn M, Samuel VT, Shulman GI, Bennett AM: MAPK phosphatase-1 facilitates the loss of oxidative myofibers associated with obesity in mice. J Clin Invest. 2009 Dec; 2009 Nov 16. PMID: 19920356

Gould Rothberg BE, Berger AJ, Molinaro AM, Subtil A, Krauthammer MO, Camp RL, Bradley WR, Ariyan S, Kluger HM, Rimm DL: Melanoma prognostic model using tissue microarrays and genetic algorithms. J Clin Oncol. 2009 Dec 1; 2009 Nov 2. PMID: 19884546

Tran N, Alves P, Ma S, Krauthammer M: Enriching PubMed related article search with sentence level co-citations. AMIA Annu Symp Proc. 2009 Nov 14; 2009 Nov 14. PMID: 20351935

Tran N, Michel G, Krauthammer M, Shiffman RN: Embedding the guideline elements model in web ontology language. AMIA Annu Symp Proc. 2009 Nov 14; 2009 Nov 14. PMID: 20351934

Baldassarre M, Razinia Z, Burande CF, Lamsoul I, Lutz PG, Calderwood DA: Filamins regulate cell spreading and initiation of cell migration. PLoS One. 2009 Nov 13; 2009 Nov 13. PMID: 19915675

Casuscelli J, Schmidt S, DeGray B, Petri ET, Celić A, Folta-Stogniew E, Ehrlich BE, Boggon TJ: Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2. Am J Physiol Renal Physiol. 2009 Nov; 2009 Sep 2. PMID: 19726544

Sidani S, Kopic S, Socrates T, Kirchhoff P, Föller M, Murek M, Capasso A, Geibel JP: AMP-activated protein kinase: a physiological off switch for murine gastric acid secretion. Pflugers Arch. 2009 Nov; 2009 Jul 21. PMID: 19621238

Caescu CI, Jeschke GR, Turk BE: Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10. Biochem J. 2009 Oct 23; 2009 Oct 23. PMID: 19715556

Kukreja A, Radfar S, Sun BH, Insogna K, Dhodapkar MV: Dominant role of CD47-thrombospondin-1 interactions in myeloma-induced fusion of human dendritic cells: implications for bone disease. Blood. 2009 Oct 15; 2009 Aug 6. PMID: 19661269

Yu J, Fernández-Hernando C, Suarez Y, Schleicher M, Hao Z, Wright PL, DiLorenzo A, Kyriakides TR, Sessa WC: Reticulon 4B (Nogo-B) is necessary for macrophage infiltration and tissue repair. Proc Natl Acad Sci U S A. 2009 Oct 13; 2009 Sep 25. PMID: 19805174

Carlson J, Cui W, Zhang Q, Xu X, Mercan F, Bennett AM, Vignery A: Role of MKP-1 in osteoclasts and bone homeostasis. Am J Pathol. 2009 Oct; 2009 Sep 17. PMID: 19762714

McCusker JP, Phillips JA, González Beltrán A, Finkelstein A, Krauthammer M: Semantic web data warehousing for caGrid. BMC Bioinformatics. 2009 Oct 1; 2009 Oct 1. PMID: 19796399

Bradley WD, Koleske AJ: Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts. J Cell Sci. 2009 Oct 1. PMID: 19759284

Soulsby M, Bennett AM: Physiological signaling specificity by protein tyrosine phosphatases. Physiology (Bethesda). 2009 Oct. PMID: 19815854

Gourley SL, Koleske AJ, Taylor JR: Loss of dendrite stabilization by the Abl-related gene (Arg) kinase regulates behavioral flexibility and sensitivity to cocaine. Proc Natl Acad Sci U S A. 2009 Sep 29; 2009 Sep 11. PMID: 19805386

Stark R, Pasquel F, Turcu A, Pongratz RL, Roden M, Cline GW, Shulman GI, Kibbey RG: Phosphoenolpyruvate cycling via mitochondrial phosphoenolpyruvate carboxykinase links anaplerosis and mitochondrial GTP with insulin secretion. J Biol Chem. 2009 Sep 25; 2009 Jul 27. PMID: 19635791

Shivakumar P, Krauthammer M: Structural similarity assessment for drug sensitivity prediction in cancer. BMC Bioinformatics. 2009 Sep 17; 2009 Sep 17. PMID: 19761571

Jilaveanu LB, Zito CR, Aziz SA, Conrad PJ, Schmitz JC, Sznol M, Camp RL, Rimm DL, Kluger HM: C-Raf is associated with disease progression and cell proliferation in a subset of melanomas. Clin Cancer Res. 2009 Sep 15; 2009 Sep 8. PMID: 19737955

Knauf F, Desir GV, Perazella MA: A case of extreme hemodynamic lability and hypocalcemia. Am J Med Sci. 2009 Sep. PMID: 19590425

Liang G, Katz LD, Insogna KL, Carpenter TO, Macica CM: Survey of the enthesopathy of X-linked hypophosphatemia and its characterization in Hyp mice. Calcif Tissue Int. 2009 Sep; 2009 Jul 17. PMID: 19609735

Harrison KD, Miao RQ, Fernandez-Hernándo C, Suárez Y, Dávalos A, Sessa WC: Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking. Cell Metab. 2009 Sep. PMID: 19723497

Di Lorenzo A, Fernández-Hernando C, Cirino G, Sessa WC: Akt1 is critical for acute inflammation and histamine-mediated vascular leakage. Proc Natl Acad Sci U S A. 2009 Aug 25; 2009 Jul 21. PMID: 19622728

Chen H, Ko G, Zatti A, Di Giacomo G, Liu L, Raiteri E, Perucco E, Collesi C, Min W, Zeiss C, De Camilli P, Cremona O: Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice. Proc Natl Acad Sci U S A. 2009 Aug 18; 2009 Aug 5. PMID: 19666558

Margulies D, Opatowsky Y, Fletcher S, Saraogi I, Tsou LK, Saha S, Lax I, Schlessinger J, Hamilton AD: Surface binding inhibitors of the SCF-KIT protein-protein interaction. Chembiochem. 2009 Aug 17. PMID: 19637142

Bae JH, Lew ED, Yuzawa S, Tomé F, Lax I, Schlessinger J: The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site. Cell. 2009 Aug 7. PMID: 19665973

Koga Y, Pelizzola M, Cheng E, Krauthammer M, Sznol M, Ariyan S, Narayan D, Molinaro AM, Halaban R, Weissman SM: Genome-wide screen of promoter methylation identifies novel markers in melanoma. Genome Res. 2009 Aug; 2009 Jun 2. PMID: 19491193

Desir GV: Regulation of blood pressure and cardiovascular function by renalase. Kidney Int. 2009 Aug; 2009 May 27. PMID: 19471322

Letinic K, Sebastian R, Toomre D, Rakic P: Exocyst is involved in polarized cell migration and cerebral cortical development. Proc Natl Acad Sci U S A. 2009 Jul 7; 2009 Jun 19. PMID: 19549839

Fernández-Hernando C, Yu J, Suárez Y, Rahner C, Dávalos A, Lasunción MA, Sessa WC: Genetic evidence supporting a critical role of endothelial caveolin-1 during the progression of atherosclerosis. Cell Metab. 2009 Jul. PMID: 19583953

Pongratz RL, Kibbey RG, Kirkpatrick CL, Zhao X, Pontoglio M, Yaniv M, Wollheim CB, Shulman GI, Cline GW: Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets. J Biol Chem. 2009 Jun 19; 2009 Apr 17. PMID: 19376774

Anagnostou VK, Bepler G, Syrigos KN, Tanoue L, Gettinger S, Homer RJ, Boffa D, Detterbeck F, Rimm DL: High expression of mammalian target of rapamycin is associated with better outcome for patients with early stage lung adenocarcinoma. Clin Cancer Res. 2009 Jun 15; 2009 Jun 9. PMID: 19509151

Lulo J, Yuzawa S, Schlessinger J: Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2. Biochem Biophys Res Commun. 2009 Jun 5; 2009 Apr 7. PMID: 19358827

Giltnane JM, Moeder CB, Camp RL, Rimm DL: Quantitative multiplexed analysis of ErbB family coexpression for primary breast cancer prognosis in a large retrospective cohort. Cancer. 2009 Jun 1. PMID: 19330842

Carlson J, Zhang Q, Bennett A, Vignery A: Deletion of mitogen-activated protein kinase phosphatase 1 modifies the response to mechanical bone marrow ablation in a mouse model. Comp Med. 2009 Jun. PMID: 19619411

Horsley V: Epigenetics, Wnt signaling, and stem cells: the Pygo2 connection. J Cell Biol. 2009 Jun 1. PMID: 19487452

Funakoshi M, Tomko RJ Jr, Kobayashi H, Hochstrasser M: Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base. Cell. 2009 May 29; 2009 May 14. PMID: 19446322

Stabach PR, Simonović I, Ranieri MA, Aboodi MS, Steitz TA, Simonović M, Morrow JS: The structure of the ankyrin-binding site of beta-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties. Blood. 2009 May 28; 2009 Jan 23. PMID: 19168783

Yu L, Min W, He Y, Qin L, Zhang H, Bennett AM, Chen H: JAK2 and SHP2 reciprocally regulate tyrosine phosphorylation and stability of proapoptotic protein ASK1. J Biol Chem. 2009 May 15; 2009 Mar 13. PMID: 19287004

Szpakowski S, McCusker J, Krauthammer M: Using semantic web technologies to annotate and align microarray designs. Cancer Inform. 2009; 2009 May 13. PMID: 24904201

Lapetina S, Mader CC, Machida K, Mayer BJ, Koleske AJ: Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion. J Cell Biol. 2009 May 4. PMID: 19414610

Harigopal M, Heymann J, Ghosh S, Anagnostou V, Camp RL, Rimm DL: Estrogen receptor co-activator (AIB1) protein expression by automated quantitative analysis (AQUA) in a breast cancer tissue microarray and association with patient outcome. Breast Cancer Res Treat. 2009 May; 2008 Jun 3. PMID: 18521745

Aziz SA, Davies M, Pick E, Zito C, Jilaveanu L, Camp RL, Rimm DL, Kluger Y, Kluger HM: Phosphatidylinositol-3-kinase as a therapeutic target in melanoma. Clin Cancer Res. 2009 May 1; 2009 Apr 21. PMID: 19383818

Harburger DS, Bouaouina M, Calderwood DA: Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects. J Biol Chem. 2009 Apr 24; 2009 Feb 23. PMID: 19240021

Patel JC, Hueffer K, Lam TT, Galán JE: Diversification of a Salmonella virulence protein function by ubiquitin-dependent differential localization. Cell. 2009 Apr 17. PMID: 19379694

Lazova R, Gould Rothberg BE, Rimm D, Scott G: The semaphorin 7A receptor Plexin C1 is lost during melanoma metastasis. Am J Dermatopathol. 2009 Apr. PMID: 19318806

Yao GQ, Wu JJ, Ovadia S, Troiano N, Sun BH, Insogna K: Targeted overexpression of the two colony-stimulating factor-1 isoforms in osteoblasts differentially affects bone loss in ovariectomized mice. Am J Physiol Endocrinol Metab. 2009 Apr; 2009 Jan 13. PMID: 19141689

Dai S, He Y, Zhang H, Yu L, Wan T, Xu Z, Jones D, Chen H, Min W: Endothelial-specific expression of mitochondrial thioredoxin promotes ischemia-mediated arteriogenesis and angiogenesis. Arterioscler Thromb Vasc Biol. 2009 Apr; 2009 Jan 15. PMID: 19150880

Gould Rothberg BE, Bracken MB, Rimm DL: Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis. J Natl Cancer Inst. 2009 Apr 1; 2009 Mar 24. PMID: 19318635

Kroetz MB, Su D, Hochstrasser M: Essential role of nuclear localization for yeast Ulp2 SUMO protease function. Mol Biol Cell. 2009 Apr; 2009 Feb 18. PMID: 19225149

Hochstrasser M: Origin and function of ubiquitin-like proteins. Nature. 2009 Mar 26. PMID: 19325621

Zoncu R, Perera RM, Balkin DM, Pirruccello M, Toomre D, De Camilli P: A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes. Cell. 2009 Mar 20. PMID: 19303853

Insogna KL: The effect of proton pump-inhibiting drugs on mineral metabolism. Am J Gastroenterol. 2009 Mar. PMID: 19262542

Christy CJ, Thorsteinsson D, Grube BJ, Black D, Abu-Khalaf M, Chung GG, DiGiovanna MP, Miller K, Higgins SA, Weidhaas J, Harris L, Tavassoli FA, Lannin DR: Preoperative chemotherapy decreases the need for re-excision of breast cancers between 2 and 4 cm diameter. Ann Surg Oncol. 2009 Mar; 2009 Jan 9. PMID: 19132447

Soliman EM, Rodrigues MA, Gomes DA, Sheung N, Yu J, Amaya MJ, Nathanson MH, Dranoff JA: Intracellular calcium signals regulate growth of hepatic stellate cells via specific effects on cell cycle progression. Cell Calcium. 2009 Mar; 2009 Jan 7. PMID: 19131107

Funakoshi M, Hochstrasser M: Small epitope-linker modules for PCR-based C-terminal tagging in Saccharomyces cerevisiae. Yeast. 2009 Mar. PMID: 19243080

Suárez Y, Sessa WC: MicroRNAs as novel regulators of angiogenesis. Circ Res. 2009 Feb 27. PMID: 19246688

Lew ED, Furdui CM, Anderson KS, Schlessinger J: The precise sequence of FGF receptor autophosphorylation is kinetically driven and is disrupted by oncogenic mutations. Sci Signal. 2009 Feb 17; 2009 Feb 17. PMID: 19224897

Jilaveanu L, Zito C, Lee SJ, Nathanson KL, Camp RL, Rimm DL, Flaherty KT, Kluger HM: Expression of sorafenib targets in melanoma patients treated with carboplatin, paclitaxel and sorafenib. Clin Cancer Res. 2009 Feb 1. PMID: 19188183

Sullivan CA, Ghosh S, Ocal IT, Camp RL, Rimm DL, Chung GG: Microvessel area using automated image analysis is reproducible and is associated with prognosis in breast cancer. Hum Pathol. 2009 Feb; 2008 Sep 16. PMID: 18799189

Stern DF: BRCTing up is hard to do. Mol Cell. 2009 Jan 30. PMID: 19187753

Harburger DS, Calderwood DA: Integrin signalling at a glance. J Cell Sci. 2009 Jan 15. PMID: 19118207

Anagnostou VK, Syrigos KN, Bepler G, Homer RJ, Rimm DL: Thyroid transcription factor 1 is an independent prognostic factor for patients with stage I lung adenocarcinoma. J Clin Oncol. 2009 Jan 10; 2008 Dec 8. PMID: 19064983

Hanna JA, Bordeaux J, Rimm DL, Agarwal S: The function, proteolytic processing, and histopathology of Met in cancer. Adv Cancer Res. 2009. PMID: 19854350

Pober JS, Min W, Bradley JR: Mechanisms of endothelial dysfunction, injury, and death. Annu Rev Pathol. 2009. PMID: 18754744

Geibel JP, Hebert SC: The functions and roles of the extracellular Ca2+-sensing receptor along the gastrointestinal tract. Annu Rev Physiol. 2009. PMID: 19575679

Emerson JW, Dolled-Filhart M, Harris L, Rimm DL, Tuck DP: Quantitative assessment of tissue biomarkers and construction of a model to predict outcome in breast cancer using multiple imputation. Cancer Inform. 2009; 2008 Dec 23. PMID: 19352457

Pongratz RL, Kibbey RG, Cline GW: Investigating the roles of mitochondrial and cytosolic malic enzyme in insulin secretion. Methods Enzymol. 2009. PMID: 19426882

Moeder CB, Giltnane JM, Moulis SP, Rimm DL: Quantitative, fluorescence-based in-situ assessment of protein expression. Methods Mol Biol. 2009. PMID: 19381954

Turk BE: Mixture-based peptide libraries for identifying protease cleavage motifs. Methods Mol Biol. 2009. PMID: 19377969

Kroetz MB, Hochstrasser M: Identification of SUMO-interacting proteins by yeast two-hybrid analysis. Methods Mol Biol. 2009. PMID: 19107413

Halaban R, Krauthammer M, Pelizzola M, Cheng E, Kovacs D, Sznol M, Ariyan S, Narayan D, Bacchiocchi A, Molinaro A, Kluger Y, Deng M, Tran N, Zhang W, Picardo M, Enghild JJ: Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications. PLoS One. 2009; 2009 Feb 23. PMID: 19234609

Nath AK, Krauthammer M, Li P, Davidov E, Butler LC, Copel J, Katajamaa M, Oresic M, Buhimschi I, Buhimschi C, Snyder M, Madri JA: Proteomic-based detection of a protein cluster dysregulated during cardiovascular development identifies biomarkers of congenital heart defects. PLoS One. 2009; 2009 Jan 19. PMID: 19156209

Chiswell BP, Zhang R, Murphy JW, Boggon TJ, Calderwood DA: The structural basis of integrin-linked kinase-PINCH interactions. Proc Natl Acad Sci U S A. 2008 Dec 30; 2008 Dec 12. PMID: 19074270

Tang PC, Qin L, Zielonka J, Zhou J, Matte-Martone C, Bergaya S, van Rooijen N, Shlomchik WD, Min W, Sessa WC, Pober JS, Tellides G: MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries. J Exp Med. 2008 Dec 22; 2008 Dec 8. PMID: 19064699

Lad Y, Jiang P, Ruskamo S, Harburger DS, Ylänne J, Campbell ID, Calderwood DA: Structural basis of the migfilin-filamin interaction and competition with integrin beta tails. J Biol Chem. 2008 Dec 12; 2008 Sep 30. PMID: 18829455

Ghosh S, Sullivan CA, Zerkowski MP, Molinaro AM, Rimm DL, Camp RL, Chung GG: High levels of vascular endothelial growth factor and its receptors (VEGFR-1, VEGFR-2, neuropilin-1) are associated with worse outcome in breast cancer. Hum Pathol. 2008 Dec; 2008 Aug 20. PMID: 18715621

Zhang H, He Y, Dai S, Xu Z, Luo Y, Wan T, Luo D, Jones D, Tang S, Chen H, Sessa WC, Min W: AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice. J Clin Invest. 2008 Dec; 2008 Nov 3. PMID: 19033661

Camp RL, Neumeister V, Rimm DL: A decade of tissue microarrays: progress in the discovery and validation of cancer biomarkers. J Clin Oncol. 2008 Dec 1; 2008 Oct 20. PMID: 18936473

Hadjidemetriou S, Toomre D, Duncan J: Motion tracking of the outer tips of microtubules. Med Image Anal. 2008 Dec; 2008 May 16. PMID: 18571462

Wilson KA, Stern DF: NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway. Cell Cycle. 2008 Nov 15; 2008 Nov 29. PMID: 19001859

Xu S, McCusker J, Krauthammer M: Exploring the use of image text for biomedical literature retrieval. AMIA Annu Symp Proc. 2008 Nov 6; 2008 Nov 6. PMID: 18999241

Stabach PR, Devarajan P, Stankewich MC, Bannykh S, Morrow JS: Ankyrin facilitates intracellular trafficking of alpha1-Na+-K+-ATPase in polarized cells. Am J Physiol Cell Physiol. 2008 Nov; 2008 Sep 3. PMID: 18768923

Gustavson MD, Molinaro AM, Tedeschi G, Camp RL, Rimm DL: AQUA analysis of thymidylate synthase reveals localization to be a key prognostic biomarker in 2 large cohorts of colorectal carcinoma. Arch Pathol Lab Med. 2008 Nov. PMID: 18976010

Rodrigues MA, Gomes DA, Andrade VA, Leite MF, Nathanson MH: Insulin induces calcium signals in the nucleus of rat hepatocytes. Hepatology. 2008 Nov. PMID: 18798337

Wang L, Dong H, Soroka CJ, Wei N, Boyer JL, Hochstrasser M: Degradation of the bile salt export pump at endoplasmic reticulum in progressive familial intrahepatic cholestasis type II. Hepatology. 2008 Nov. PMID: 18798335

Celić A, Petri ET, Demeler B, Ehrlich BE, Boggon TJ: Domain mapping of the polycystin-2 C-terminal tail using de novo molecular modeling and biophysical analysis. J Biol Chem. 2008 Oct 17; 2008 Aug 11. PMID: 18694932

Sangerman J, Maksimova Y, Edelman EJ, Morrow JS, Forget BG, Gallagher PG: Ankyrin-linked hereditary spherocytosis in an African-American kindred. Am J Hematol. 2008 Oct. PMID: 18704959

Giltnane JM, Molinaro A, Cheng H, Robinson A, Turbin D, Gelmon K, Huntsman D, Rimm DL: Comparison of quantitative immunofluorescence with conventional methods for HER2/neu testing with respect to response to trastuzumab therapy in metastatic breast cancer. Arch Pathol Lab Med. 2008 Oct. PMID: 18834223

Page K, Bergwitz C, Jaureguiberry G, Harinarayan CV, Insogna K: A patient with hypophosphatemia, a femoral fracture, and recurrent kidney stones: report of a novel mutation in SLC34A3. Endocr Pract. 2008 Oct. PMID: 18996815

Pelizzola M, Koga Y, Urban AE, Krauthammer M, Weissman S, Halaban R, Molinaro AM: MEDME: an experimental and analytical methodology for the estimation of DNA methylation levels based on microarray derived MeDIP-enrichment. Genome Res. 2008 Oct; 2008 Sep 2. PMID: 18765822

Suárez Y, Fernández-Hernando C, Yu J, Gerber SA, Harrison KD, Pober JS, Iruela-Arispe ML, Merkenschlager M, Sessa WC: Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis. Proc Natl Acad Sci U S A. 2008 Sep 16; 2008 Sep 8. PMID: 18779589

Mamillapalli R, VanHouten J, Zawalich W, Wysolmerski J: Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells. J Biol Chem. 2008 Sep 5; 2008 Jul 11. PMID: 18621740

Xu S, McCusker J, Krauthammer M: Yale Image Finder (YIF): a new search engine for retrieving biomedical images. Bioinformatics. 2008 Sep 1; 2008 Jul 9. PMID: 18614584

Kusmierczyk AR, Hochstrasser M: Some assembly required: dedicated chaperones in eukaryotic proteasome biogenesis. Biol Chem. 2008 Sep. PMID: 18713001

Rothberg BE, Moeder CB, Kluger H, Halaban R, Elder DE, Murphy GF, Lazar A, Prieto V, Duncan LM, Rimm DL: Nuclear to non-nuclear Pmel17/gp100 expression (HMB45 staining) as a discriminator between benign and malignant melanocytic lesions. Mod Pathol. 2008 Sep; 2008 Jun 13. PMID: 18552823

Nishihori T, Choi J, DiGiovanna MP, Thomson JG, Kohler PC, McGurn J, Chung GG: Carpal tunnel syndrome associated with the use of aromatase inhibitors in breast cancer. Clin Breast Cancer. 2008 Aug. PMID: 18757265

Kawano T, Troiano N, Adams DJ, Wu JJ, Sun BH, Insogna K: The anabolic response to parathyroid hormone is augmented in Rac2 knockout mice. Endocrinology. 2008 Aug; 2008 May 8. PMID: 18467443

Yono M, Mane SM, Lin A, Weiss RM, Latifpour J: Differential effects of diabetes induced by streptozotocin and that develops spontaneously on prostate growth in Bio Breeding (BB) rats. Life Sci. 2008 Aug 1; 2008 Jun 20. PMID: 18619471

Nadler Y, Camp RL, Schwartz C, Rimm DL, Kluger HM, Kluger Y: Expression of Aurora A (but not Aurora B) is predictive of survival in breast cancer. Clin Cancer Res. 2008 Jul 15. PMID: 18628459

Sheridan DL, Kong Y, Parker SA, Dalby KN, Turk BE: Substrate discrimination among mitogen-activated protein kinases through distinct docking sequence motifs. J Biol Chem. 2008 Jul 11; 2008 May 15. PMID: 18482985

Grube BJ, Christy CJ, Black D, Martel M, Harris L, Weidhaas J, Digiovanna MP, Chung G, Abu-Khalaf MM, Miller KD, Higgins SA, Philpotts L, Tavassoli FA, Lannin DR: Breast sentinel lymph node dissection before preoperative chemotherapy. Arch Surg. 2008 Jul. PMID: 18645113

Knobf MT, Insogna K, DiPietro L, Fennie C, Thompson AS: An aerobic weight-loaded pilot exercise intervention for breast cancer survivors: bone remodeling and body composition outcomes. Biol Res Nurs. 2008 Jul. PMID: 18705153

Zito CI, Riches D, Kolmakova J, Simons J, Egholm M, Stern DF: Direct resequencing of the complete ERBB2 coding sequence reveals an absence of activating mutations in ERBB2 amplified breast cancer. Genes Chromosomes Cancer. 2008 Jul. PMID: 18418848

Insogna K: Can serum pentosidine levels predict risk of vertebral fracture in patients with type 2 diabetes mellitus? Nat Clin Pract Endocrinol Metab. 2008 Jul; 2008 May 6. PMID: 18461065

Goss JW, Toomre DK: Both daughter cells traffic and exocytose membrane at the cleavage furrow during mammalian cytokinesis. J Cell Biol. 2008 Jun 30; 2008 Jun 23. PMID: 18573914

Yang Y, Yuzawa S, Schlessinger J: Contacts between membrane proximal regions of the PDGF receptor ectodomain are required for receptor activation but not for receptor dimerization. Proc Natl Acad Sci U S A. 2008 Jun 3; 2008 May 27. PMID: 18505839

Psyrri A, Egleston B, Weinberger P, Yu Z, Kowalski D, Sasaki C, Haffty B, Rimm D, Burtness B: Correlates and determinants of nuclear epidermal growth factor receptor content in an oropharyngeal cancer tissue microarray. Cancer Epidemiol Biomarkers Prev. 2008 Jun. PMID: 18559565

Stern DF: ERBB3/HER3 and ERBB2/HER2 duet in mammary development and breast cancer. J Mammary Gland Biol Neoplasia. 2008 Jun; 2008 May 3. PMID: 18454306

Eminaga S, Bennett AM: Noonan syndrome-associated SHP-2/Ptpn11 mutants enhance SIRPalpha and PZR tyrosyl phosphorylation and promote adhesion-mediated ERK activation. J Biol Chem. 2008 May 30; 2008 Mar 31. PMID: 18378677

DiGiovanna MP, Stern DF, Edgerton S, Broadwater G, Dressler LG, Budman DR, Henderson IC, Norton L, Liu ET, Muss HB, Berry DA, Hayes DF, Thor AD: Influence of activation state of ErbB-2 (HER-2) on response to adjuvant cyclophosphamide, doxorubicin, and fluorouracil for stage II, node-positive breast cancer: study 8541 from the Cancer and Leukemia Group B. J Clin Oncol. 2008 May 10; 2008 Apr 7. PMID: 18390970

Luo D, He Y, Zhang H, Yu L, Chen H, Xu Z, Tang S, Urano F, Min W: AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response. J Biol Chem. 2008 May 2; 2008 Feb 15. PMID: 18281285

Min W, Lin Y, Tang S, Yu L, Zhang H, Wan T, Luhn T, Fu H, Chen H: AIP1 recruits phosphatase PP2A to ASK1 in tumor necrosis factor-induced ASK1-JNK activation. Circ Res. 2008 Apr 11; 2008 Feb 21. PMID: 18292600

Kreizenbeck GM, Berger AJ, Subtil A, Rimm DL, Gould Rothberg BE: Prognostic significance of cadherin-based adhesion molecules in cutaneous malignant melanoma. Cancer Epidemiol Biomarkers Prev. 2008 Apr. PMID: 18398036

Kumar A, Petri ET, Halmos B, Boggon TJ: Structure and clinical relevance of the epidermal growth factor receptor in human cancer. J Clin Oncol. 2008 Apr 1. PMID: 18375904

Boras-Granic K, Wysolmerski JJ: Wnt signaling in breast organogenesis. Organogenesis. 2008 Apr. PMID: 19279723

Jia-Lin Ma N, Stern DF: Regulation of the Rad53 protein kinase in signal amplification by oligomer assembly and disassembly. Cell Cycle. 2008 Mar 15; 2008 Jan 8. PMID: 18239457

Li G, Xu J, Wang P, Velazquez H, Li Y, Wu Y, Desir GV: Catecholamines regulate the activity, secretion, and synthesis of renalase. Circulation. 2008 Mar 11; 2008 Feb 25. PMID: 18299506

Idone V, Tam C, Goss JW, Toomre D, Pypaert M, Andrews NW: Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis. J Cell Biol. 2008 Mar 10; 2008 Mar 3. PMID: 18316410

Bouaouina M, Lad Y, Calderwood DA: The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins. J Biol Chem. 2008 Mar 7; 2007 Dec 28. PMID: 18165225

Chakraborty AK, Liang K, DiGiovanna MP: Co-targeting insulin-like growth factor I receptor and HER2: dramatic effects of HER2 inhibitors on nonoverexpressing breast cancer. Cancer Res. 2008 Mar 1. PMID: 18316619

Desir GV: Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease. Curr Opin Nephrol Hypertens. 2008 Mar. PMID: 18277152

Nakchbandi IA, Lang R, Kinder B, Insogna KL: The role of the receptor activator of nuclear factor-kappaB ligand/osteoprotegerin cytokine system in primary hyperparathyroidism. J Clin Endocrinol Metab. 2008 Mar; 2007 Dec 11. PMID: 18073309

Kusmierczyk AR, Kunjappu MJ, Funakoshi M, Hochstrasser M: A multimeric assembly factor controls the formation of alternative 20S proteasomes. Nat Struct Mol Biol. 2008 Mar; 2008 Feb 17. PMID: 18278055

Mansoor I, Zalles C, Zahid F, Gossage K, Levenson RM, Rimm DL: Fine-needle aspiration of follicular adenoma versus parathyroid adenoma: the utility of multispectral imaging in differentiating lesions with subtle cytomorphologic differences. Cancer. 2008 Feb 25. PMID: 18085636

Gomes DA, Rodrigues MA, Leite MF, Gomez MV, Varnai P, Balla T, Bennett AM, Nathanson MH: c-Met must translocate to the nucleus to initiate calcium signals. J Biol Chem. 2008 Feb 15; 2007 Dec 11. PMID: 18073207

Turk BE: Understanding and exploiting substrate recognition by protein kinases. Curr Opin Chem Biol. 2008 Feb; 2008 Mar 7. PMID: 18282484

Turk BE: Discovery and development of anthrax lethal factor metalloproteinase inhibitors. Curr Pharm Biotechnol. 2008 Feb. PMID: 18289054

Reiner E, Pollak JS, Henderson KJ, Weiss RM, White RI Jr: Initial experience with 3% sodium tetradecyl sulfate foam and fibered coils for management of adolescent varicocele. J Vasc Interv Radiol. 2008 Feb. PMID: 18341950

Yuzawa S, Schlessinger J: [Structural biology of receptor tyrosine kinase kit]. Seikagaku. 2008 Feb. PMID: 18341028

Schleicher M, Shepherd BR, Suarez Y, Fernandez-Hernando C, Yu J, Pan Y, Acevedo LM, Shadel GS, Sessa WC: Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence. J Cell Biol. 2008 Jan 14. PMID: 18195103

Jackson-Fisher AJ, Bellinger G, Breindel JL, Tavassoli FA, Booth CJ, Duong JK, Stern DF: ErbB3 is required for ductal morphogenesis in the mouse mammary gland. Breast Cancer Res. 2008; 2008 Nov 18. PMID: 19019207

Nadler Y, Camp RL, Giltnane JM, Moeder C, Rimm DL, Kluger HM, Kluger Y: Expression patterns and prognostic value of Bag-1 and Bcl-2 in breast cancer. Breast Cancer Res. 2008; 2008 Apr 23. PMID: 18430249

Felberbaum R, Hochstrasser M: Ulp2 and the DNA damage response: desumoylation enables safe passage through mitosis. Cell Cycle. 2008 Jan 1; 2007 Oct 28. PMID: 18196960

Rogart JN, Nagata J, Loeser CS, Roorda RD, Aslanian H, Robert ME, Zipfel WR, Nathanson MH: Multiphoton imaging can be used for microscopic examination of intact human gastrointestinal mucosa ex vivo. Clin Gastroenterol Hepatol. 2008 Jan; 2007 Dec 18. PMID: 18065276

Wang Z, Liu B, Wang P, Dong X, Fernandez-Hernando C, Li Z, Hla T, Li Z, Claffey K, Smith JD, Wu D: Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice. J Clin Invest. 2008 Jan. PMID: 18079968

Bjornson RD, Carriero NJ, Colangelo C, Shifman M, Cheung KH, Miller PL, Williams K: X!!Tandem, an improved method for running X!tandem in parallel on collections of commodity computers. J Proteome Res. 2008 Jan; 2007 Sep 29. PMID: 17902638

Destaing O, Sanjay A, Itzstein C, Horne WC, Toomre D, De Camilli P, Baron R: The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts. Mol Biol Cell. 2008 Jan; 2007 Oct 31. PMID: 17978100

Lew ED, Bae JH, Rohmann E, Wollnik B, Schlessinger J: Structural basis for reduced FGFR2 activity in LADD syndrome: Implications for FGFR autoinhibition and activation. Proc Natl Acad Sci U S A. 2007 Dec 11; 2007 Dec 3. PMID: 18056630

Takizawa BT, Uchio EM, Cohen JJ, Wheeler MA, Weiss RM: Downregulation of survivin is associated with reductions in TNF receptors' mRNA and protein and alterations in nuclear factor kappa B signaling in urothelial cancer cells. Cancer Invest. 2007 Dec. PMID: 18058462

Fernández-Hernando C, Ackah E, Yu J, Suárez Y, Murata T, Iwakiri Y, Prendergast J, Miao RQ, Birnbaum MJ, Sessa WC: Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease. Cell Metab. 2007 Dec. PMID: 18054314

VanHouten JN, Neville MC, Wysolmerski JJ: The calcium-sensing receptor regulates plasma membrane calcium adenosine triphosphatase isoform 2 activity in mammary epithelial cells: a mechanism for calcium-regulated calcium transport into milk. Endocrinology. 2007 Dec; 2007 Sep 6. PMID: 17823248

Moeder CB, Giltnane JM, Harigopal M, Molinaro A, Robinson A, Gelmon K, Huntsman D, Camp RL, Rimm DL, American Society of Clinical Oncology., College of American Pathologists.: Quantitative justification of the change from 10% to 30% for human epidermal growth factor receptor 2 scoring in the American Society of Clinical Oncology/College of American Pathologists guidelines: tumor heterogeneity in breast cancer and its implications for tissue microarray based assessment of outcome. J Clin Oncol. 2007 Dec 1. PMID: 18048824

Suárez Y, Shepherd BR, Rao DA, Pober JS: Alloimmunity to human endothelial cells derived from cord blood progenitors. J Immunol. 2007 Dec 1. PMID: 18025193

VanHouten JN, Wysolmerski JJ: Transcellular calcium transport in mammary epithelial cells. J Mammary Gland Biol Neoplasia. 2007 Dec; 2007 Nov 13. PMID: 17999165

Stone KL, Bjornson RD, Blasko GG, Bruce C, Cofrancesco R, Carriero NJ, Colangelo CM, Crawford JK, Crawford JM, daSilva NC, Deluca JD, Elliott JI, Elliott MM, Flory PJ, Folta-Stogniew EJ, Gulcicek E, Kong Y, Lam TT, Lee JY, Lin A, LoPresti MB, Mane SM, McMurray WJ, Tikhonova IR, Westman S, Williams NA, Wu TL, Hongyu Z, Williams KR: Keck Foundation Biotechnology Resource Laboratory, Yale University. Yale J Biol Med. 2007 Dec. PMID: 18449392

Xie Y, Kerscher O, Kroetz MB, McConchie HF, Sung P, Hochstrasser M: The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation. J Biol Chem. 2007 Nov 23; 2007 Sep 11. PMID: 17848550

Smith A, Cheung K, Krauthammer M, Schultz M, Gerstein M: Leveraging the structure of the Semantic Web to enhance information retrieval for proteomics. Bioinformatics. 2007 Nov 15; 2007 Oct 7. PMID: 17923450

Minagawa N, Nagata J, Shibao K, Masyuk AI, Gomes DA, Rodrigues MA, Lesage G, Akiba Y, Kaunitz JD, Ehrlich BE, Larusso NF, Nathanson MH: Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile. Gastroenterology. 2007 Nov; 2007 Aug 14. PMID: 17916355

Garcia-Tsao G, Nathanson MH: Portal hypertension: from the patient to the molecule and back: a symposium honoring Roberto J. Groszmann, MD. J Clin Gastroenterol. 2007 Nov-Dec. PMID: 17975470

Barreiro G, Kim JT, Guimarães CR, Bailey CM, Domaoal RA, Wang L, Anderson KS, Jorgensen WL: From docking false-positive to active anti-HIV agent. J Med Chem. 2007 Nov 1; 2007 Oct 6. PMID: 17918923

Li Y, Wang P, Xu J, Gorelick F, Yamazaki H, Andrews N, Desir GV: Regulation of insulin secretion and GLUT4 trafficking by the calcium sensor synaptotagmin VII. Biochem Biophys Res Commun. 2007 Oct 26; 2007 Aug 15. PMID: 17720139

Zhang D, Liu ZX, Choi CS, Tian L, Kibbey R, Dong J, Cline GW, Wood PA, Shulman GI: Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance. Proc Natl Acad Sci U S A. 2007 Oct 23; 2007 Oct 16. PMID: 17940018

Bernatchez PN, Acevedo L, Fernandez-Hernando C, Murata T, Chalouni C, Kim J, Erdjument-Bromage H, Shah V, Gratton JP, McNally EM, Tempst P, Sessa WC: Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function. J Biol Chem. 2007 Oct 19; 2007 Aug 16. PMID: 17702744

Boyle SN, Koleske AJ: Use of a chemical genetic technique to identify myosin IIb as a substrate of the Abl-related gene (Arg) tyrosine kinase. Biochemistry. 2007 Oct 16; 2007 Sep 25. PMID: 17892306

Tran N, Luong T, Krauthammer M: Mapping terms to UMLS concepts of the same semantic type. AMIA Annu Symp Proc. 2007 Oct 11; 2007 Oct 11. PMID: 18694233

Sfakianos MK, Eisman A, Gourley SL, Bradley WD, Scheetz AJ, Settleman J, Taylor JR, Greer CA, Williamson A, Koleske AJ: Inhibition of Rho via Arg and p190RhoGAP in the postnatal mouse hippocampus regulates dendritic spine maturation, synapse and dendrite stability, and behavior. J Neurosci. 2007 Oct 10. PMID: 17928439

Shifman MA, Li Y, Colangelo CM, Stone KL, Wu TL, Cheung KH, Miller PL, Williams KR: YPED: a web-accessible database system for protein expression analysis. J Proteome Res. 2007 Oct; 2007 Sep 15. PMID: 17867667

Peacock JG, Miller AL, Bradley WD, Rodriguez OC, Webb DJ, Koleske AJ: The Abl-related gene tyrosine kinase acts through p190RhoGAP to inhibit actomyosin contractility and regulate focal adhesion dynamics upon adhesion to fibronectin. Mol Biol Cell. 2007 Oct; 2007 Jul 25. PMID: 17652459

Shams I, Rohmann E, Eswarakumar VP, Lew ED, Yuzawa S, Wollnik B, Schlessinger J, Lax I: Lacrimo-auriculo-dento-digital syndrome is caused by reduced activity of the fibroblast growth factor 10 (FGF10)-FGF receptor 2 signaling pathway. Mol Cell Biol. 2007 Oct; 2007 Aug 6. PMID: 17682060

Schwartz DC, Felberbaum R, Hochstrasser M: The Ulp2 SUMO protease is required for cell division following termination of the DNA damage checkpoint. Mol Cell Biol. 2007 Oct; 2007 Jul 30. PMID: 17664284

Gil-Henn H, Destaing O, Sims NA, Aoki K, Alles N, Neff L, Sanjay A, Bruzzaniti A, De Camilli P, Baron R, Schlessinger J: Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice. J Cell Biol. 2007 Sep 10. PMID: 17846174

Lad Y, Kiema T, Jiang P, Pentikäinen OT, Coles CH, Campbell ID, Calderwood DA, Ylänne J: Structure of three tandem filamin domains reveals auto-inhibition of ligand binding. EMBO J. 2007 Sep 5; 2007 Aug 9. PMID: 17690686

Abu-Khalaf MM, Juneja V, Chung GG, DiGiovanna MP, Sipples R, McGurk M, Zelterman D, Haffty B, Reiss M, Wackers FJ, Lee FA, Burtness BA: Long-term assessment of cardiac function after dose-dense and -intense sequential doxorubicin (A), paclitaxel (T), and cyclophosphamide (C) as adjuvant therapy for high risk breast cancer. Breast Cancer Res Treat. 2007 Sep; 2006 Oct 19. PMID: 17051423

Erdmann KS, Mao Y, McCrea HJ, Zoncu R, Lee S, Paradise S, Modregger J, Biemesderfer D, Toomre D, De Camilli P: A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway. Dev Cell. 2007 Sep. PMID: 17765681

Boyle SN, Koleske AJ: Dissecting kinase signaling pathways. Drug Discov Today. 2007 Sep; 2007 Aug 23. PMID: 17826684

Kosiek O, Busque SM, Föller M, Shcheynikov N, Kirchhoff P, Bleich M, Muallem S, Geibel JP: SLC26A7 can function as a chloride-loading mechanism in parietal cells. Pflugers Arch. 2007 Sep; 2007 Apr 3. PMID: 17404755

Lewis A, Felberbaum R, Hochstrasser M: A nuclear envelope protein linking nuclear pore basket assembly, SUMO protease regulation, and mRNA surveillance. J Cell Biol. 2007 Aug 27. PMID: 17724121

Ardeshirpour L, Dann P, Adams DJ, Nelson T, VanHouten J, Horowitz MC, Wysolmerski JJ: Weaning triggers a decrease in receptor activator of nuclear factor-kappaB ligand expression, widespread osteoclast apoptosis, and rapid recovery of bone mass after lactation in mice. Endocrinology. 2007 Aug; 2007 May 10. PMID: 17495007

Correa PR, Kruglov EA, Thompson M, Leite MF, Dranoff JA, Nathanson MH: Succinate is a paracrine signal for liver damage. J Hepatol. 2007 Aug; 2007 Apr 5. PMID: 17451837

Yuzawa S, Opatowsky Y, Zhang Z, Mandiyan V, Lax I, Schlessinger J: Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor. Cell. 2007 Jul 27. PMID: 17662946

Giltnane JM, Rydén L, Cregger M, Bendahl PO, Jirström K, Rimm DL: Quantitative measurement of epidermal growth factor receptor is a negative predictive factor for tamoxifen response in hormone receptor positive premenopausal breast cancer. J Clin Oncol. 2007 Jul 20. PMID: 17634479

Xu J, Desir GV: Renalase, a new renal hormone: its role in health and disease. Curr Opin Nephrol Hypertens. 2007 Jul. PMID: 17565281

Hochstrasser M: Ubiquitin ligation without a ligase. Dev Cell. 2007 Jul. PMID: 17609103

Nagata J, Guerra MT, Shugrue CA, Gomes DA, Nagata N, Nathanson MH: Lipid rafts establish calcium waves in hepatocytes. Gastroenterology. 2007 Jul; 2007 Apr 11. PMID: 17631147

Chung GG, Zerkowski MP, Ghosh S, Camp RL, Rimm DL: Quantitative analysis of estrogen receptor heterogeneity in breast cancer. Lab Invest. 2007 Jul; 2007 Mar 5. PMID: 17334408

Rodrigues MA, Gomes DA, Leite MF, Grant W, Zhang L, Lam W, Cheng YC, Bennett AM, Nathanson MH: Nucleoplasmic calcium is required for cell proliferation. J Biol Chem. 2007 Jun 8; 2007 Apr 9. PMID: 17420246

Husain SZ, Grant WM, Gorelick FS, Nathanson MH, Shah AU: Caerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin. Am J Physiol Gastrointest Liver Physiol. 2007 Jun; 2007 Mar 1. PMID: 17332472

Barmeyer C, Ye JH, Sidani S, Geibel J, Binder HJ, Rajendran VM: Characteristics of rat downregulated in adenoma (rDRA) expressed in HEK 293 cells. Pflugers Arch. 2007 Jun; 2007 Feb 16. PMID: 17492310

Zhang H, Zhang H, Lin Y, Li J, Pober JS, Min W: RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation. J Biol Chem. 2007 May 18; 2007 Mar 27. PMID: 17389591

Li X, Kusmierczyk AR, Wong P, Emili A, Hochstrasser M: beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint. EMBO J. 2007 May 2; 2007 Apr 12. PMID: 17431397

Suárez Y, Fernández-Hernando C, Pober JS, Sessa WC: Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells. Circ Res. 2007 Apr 27; 2007 Mar 22. PMID: 17379831

Kruglov EA, Correa PR, Arora G, Yu J, Nathanson MH, Dranoff JA: Molecular basis for calcium signaling in hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol. 2007 Apr; 2007 Jan 4. PMID: 17204544

Pick E, Kluger Y, Giltnane JM, Moeder C, Camp RL, Rimm DL, Kluger HM: High HSP90 expression is associated with decreased survival in breast cancer. Cancer Res. 2007 Apr 1. PMID: 17409397

Reshetnikova G, Troyanovsky S, Rimm DL: Definition of a direct extracellular interaction between Met and E-cadherin. Cell Biol Int. 2007 Apr; 2007 Jan 21. PMID: 17336101

Kibbey RG, Pongratz RL, Romanelli AJ, Wollheim CB, Cline GW, Shulman GI: Mitochondrial GTP regulates glucose-stimulated insulin secretion. Cell Metab. 2007 Apr. PMID: 17403370

Yu KP, Itokawa T, Zhu ML, Syam S, Seth A, Insogna K: Breast cancer-associated gene 3 (BCA3) is a novel Rac1-interacting protein. J Bone Miner Res. 2007 Apr. PMID: 17227220

Ravid T, Hochstrasser M: Autoregulation of an E2 enzyme by ubiquitin-chain assembly on its catalytic residue. Nat Cell Biol. 2007 Apr; 2007 Feb 21. PMID: 17310239

Hernandez E, Leite MF, Guerra MT, Kruglov EA, Bruna-Romero O, Rodrigues MA, Gomes DA, Giordano FJ, Dranoff JA, Nathanson MH: The spatial distribution of inositol 1,4,5-trisphosphate receptor isoforms shapes Ca2+ waves. J Biol Chem. 2007 Mar 30; 2007 Feb 6. PMID: 17284437

Turk BE: Manipulation of host signalling pathways by anthrax toxins. Biochem J. 2007 Mar 15. PMID: 17313374

Zito CI, Qin H, Blenis J, Bennett AM: SHP-2 regulates cell growth by controlling the mTOR/S6 kinase 1 pathway. J Biol Chem. 2007 Mar 9; 2007 Jan 17. PMID: 17229738

Boyle SN, Michaud GA, Schweitzer B, Predki PF, Koleske AJ: A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation. Curr Biol. 2007 Mar 6; 2007 Feb 15. PMID: 17306540

Eswarakumar VP, Schlessinger J: Skeletal overgrowth is mediated by deficiency in a specific isoform of fibroblast growth factor receptor 3. Proc Natl Acad Sci U S A. 2007 Mar 6; 2007 Feb 23. PMID: 17360456

Zoncu R, Perera RM, Sebastian R, Nakatsu F, Chen H, Balla T, Ayala G, Toomre D, De Camilli PV: Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A. 2007 Mar 6; 2007 Feb 27. PMID: 17360432

Sidani SM, Kirchhoff P, Socrates T, Stelter L, Ferreira E, Caputo C, Roberts KE, Bell RL, Egan ME, Geibel JP: DeltaF508 mutation results in impaired gastric acid secretion. J Biol Chem. 2007 Mar 2; 2006 Dec 18. PMID: 17178714

Mani A, Radhakrishnan J, Wang H, Mani A, Mani MA, Nelson-Williams C, Carew KS, Mane S, Najmabadi H, Wu D, Lifton RP: LRP6 mutation in a family with early coronary disease and metabolic risk factors. Science. 2007 Mar 2. PMID: 17332414

Zhang H, Luo Y, Zhang W, He Y, Dai S, Zhang R, Huang Y, Bernatchez P, Giordano FJ, Shadel G, Sessa WC, Min W: Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions. Am J Pathol. 2007 Mar. PMID: 17322393

Yu Z, Weinberger PM, Sasaki C, Egleston BL, Speier WF 4th, Haffty B, Kowalski D, Camp R, Rimm D, Vairaktaris E, Burtness B, Psyrri A: Phosphorylation of Akt (Ser473) predicts poor clinical outcome in oropharyngeal squamous cell cancer. Cancer Epidemiol Biomarkers Prev. 2007 Mar. PMID: 17372251

Hens JR, Dann P, Zhang JP, Harris S, Robinson GW, Wysolmerski J: BMP4 and PTHrP interact to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction. Development. 2007 Mar; 2007 Feb 14. PMID: 17301089

Desir GV: Renalase is a novel renal hormone that regulates cardiovascular function. J Am Soc Hypertens. 2007 Mar-Apr. PMID: 20409839

Pozner-Moulis S, Cregger M, Camp RL, Rimm DL: Antibody validation by quantitative analysis of protein expression using expression of Met in breast cancer as a model. Lab Invest. 2007 Mar; 2007 Jan 29. PMID: 17260003

O'Brien EM, Gomes DA, Sehgal S, Nathanson MH: Hormonal regulation of nuclear permeability. J Biol Chem. 2007 Feb 9; 2006 Dec 7. PMID: 17158097

Zerkowski MP, Camp RL, Burtness BA, Rimm DL, Chung GG: Quantitative analysis of breast cancer tissue microarrays shows high cox-2 expression is associated with poor outcome. Cancer Invest. 2007 Feb. PMID: 17364553

Bouyer P, Sakai H, Itokawa T, Kawano T, Fulton CM, Boron WF, Insogna KL: Colony-stimulating factor-1 increases osteoclast intracellular pH and promotes survival via the electroneutral Na/HCO3 cotransporter NBCn1. Endocrinology. 2007 Feb; 2006 Oct 26. PMID: 17068143

Kluger HM, McCarthy MM, Alvero AB, Sznol M, Ariyan S, Camp RL, Rimm DL, Mor G: The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitization. J Transl Med. 2007 Jan 26; 2007 Jan 26. PMID: 17257402

Glantz SB, Cianci CD, Iyer R, Pradhan D, Wang KK, Morrow JS: Sequential degradation of alphaII and betaII spectrin by calpain in glutamate or maitotoxin-stimulated cells. Biochemistry. 2007 Jan 16. PMID: 17209560

Pongratz RL, Kibbey RG, Shulman GI, Cline GW: Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion. J Biol Chem. 2007 Jan 5; 2006 Nov 13. PMID: 17102138

Gelernter J, Panhuysen C, Weiss R, Brady K, Poling J, Krauthammer M, Farrer L, Kranzler HR: Genomewide linkage scan for nicotine dependence: identification of a chromosome 5 risk locus. Biol Psychiatry. 2007 Jan 1; 2006 Nov 1. PMID: 17081504

Lang PA, Schniepp R, Kirchhoff P, Socrates T, Sidani SM, Geibel JP: PI3 kinase dependent stimulation of gastric acid secretion by dexamethasone. Cell Physiol Biochem. 2007. PMID: 17762179

Lad Y, Harburger DS, Calderwood DA: Integrin cytoskeletal interactions. Methods Enzymol. 2007. PMID: 17697880

Stone KL, Crawford M, McMurray W, Williams N, Williams KR: Identification of proteins based on MS/MS spectra and location of posttranslational modifications. Methods Mol Biol. 2007. PMID: 18604942

Iwakiri Y, Satoh A, Chatterjee S, Toomre DK, Chalouni CM, Fulton D, Groszmann RJ, Shah VH, Sessa WC: Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking. Proc Natl Acad Sci U S A. 2006 Dec 26; 2006 Dec 14. PMID: 17170139

Perera RM, Zoncu R, Lucast L, De Camilli P, Toomre D: Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages. Proc Natl Acad Sci U S A. 2006 Dec 19; 2006 Dec 8. PMID: 17158794

Kim JT, Hamilton AD, Bailey CM, Domaoal RA, Wang L, Anderson KS, Jorgensen WL: FEP-guided selection of bicyclic heterocycles in lead optimization for non-nucleoside inhibitors of HIV-1 reverse transcriptase. J Am Chem Soc. 2006 Dec 6. PMID: 17131993

Sakai H, Chen Y, Itokawa T, Yu KP, Zhu ML, Insogna K: Activated c-Fms recruits Vav and Rac during CSF-1-induced cytoskeletal remodeling and spreading in osteoclasts. Bone. 2006 Dec; 2006 Sep 1. PMID: 16950670

Simonovic M, Zhang Z, Cianci CD, Steitz TA, Morrow JS: Structure of the calmodulin alphaII-spectrin complex provides insight into the regulation of cell plasticity. J Biol Chem. 2006 Nov 10; 2006 Aug 31. PMID: 16945920

Luo D, Luo Y, He Y, Zhang H, Zhang R, Li X, Dobrucki WL, Sinusas AJ, Sessa WC, Min W: Differential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis. Am J Pathol. 2006 Nov. PMID: 17071609

Thakur VV, Kim JT, Hamilton AD, Bailey CM, Domaoal RA, Wang L, Anderson KS, Jorgensen WL: Optimization of pyrimidinyl- and triazinyl-amines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem Lett. 2006 Nov 1; 2006 Aug 22. PMID: 16931015

Dolled-Filhart M, Rydén L, Cregger M, Jirström K, Harigopal M, Camp RL, Rimm DL: Classification of breast cancer using genetic algorithms and tissue microarrays. Clin Cancer Res. 2006 Nov 1. PMID: 17085660

Bradley WD, Hernández SE, Settleman J, Koleske AJ: Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane. Mol Biol Cell. 2006 Nov; 2006 Sep 13. PMID: 16971514

Deng M, Hochstrasser M: Spatially regulated ubiquitin ligation by an ER/nuclear membrane ligase. Nature. 2006 Oct 19. PMID: 17051211

Fornaro M, Burch PM, Yang W, Zhang L, Hamilton CE, Kim JH, Neel BG, Bennett AM: SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth. J Cell Biol. 2006 Oct 9; 2006 Oct 2. PMID: 17015617

Schlessinger J, Lemmon MA: Nuclear signaling by receptor tyrosine kinases: the first robin of spring. Cell. 2006 Oct 6. PMID: 17018275

He Y, Luo Y, Tang S, Rajantie I, Salven P, Heil M, Zhang R, Luo D, Li X, Chi H, Yu J, Carmeliet P, Schaper W, Sinusas AJ, Sessa WC, Alitalo K, Min W: Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis. J Clin Invest. 2006 Sep; 2006 Aug 24. PMID: 16932810

Yono M, Foster HE Jr, Weiss RM, Latifpour J: Age related changes in the functional, biochemical and molecular properties of alpha1-adrenoceptors in the rat genitourinary tract. J Urol. 2006 Sep. PMID: 16890728

Murata T, Delprato A, Ingmundson A, Toomre DK, Lambright DG, Roy CR: The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor. Nat Cell Biol. 2006 Sep; 2006 Aug 13. PMID: 16906144

Pozner-Moulis S, Pappas DJ, Rimm DL: Met, the hepatocyte growth factor receptor, localizes to the nucleus in cells at low density. Cancer Res. 2006 Aug 15. PMID: 16912172

Shepherd BR, Enis DR, Wang F, Suarez Y, Pober JS, Schechner JS: Vascularization and engraftment of a human skin substitute using circulating progenitor cell-derived endothelial cells. FASEB J. 2006 Aug; 2006 Jun 28. PMID: 16807367

Weiss RM, Tamarkin FJ, Wheeler MA: Pacemaker activity in the upper urinary tract. J Smooth Muscle Res. 2006 Aug. PMID: 17099294

Rimm DL: What brown cannot do for you. Nat Biotechnol. 2006 Aug. PMID: 16900128

Tamarkin FJ, Kang WS, Cohen JJ, Wheeler MA, Weiss RM: A role for Akt in the rapid regulation of inflammatory and apoptotic pathways in mouse bladder. Naunyn Schmiedebergs Arch Pharmacol. 2006 Aug; 2006 Jul 11. PMID: 16832691

Fernández-Hernando C, Fukata M, Bernatchez PN, Fukata Y, Lin MI, Bredt DS, Sessa WC: Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase. J Cell Biol. 2006 Jul 31; 2006 Jul 24. PMID: 16864653

Arteaga MF, Wang L, Ravid T, Hochstrasser M, Canessa CM: An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery. Proc Natl Acad Sci U S A. 2006 Jul 25; 2006 Jul 17. PMID: 16847254

Ghosh S, Choritz L, Geibel J, Coca-Prados M: Somatostatin modulates PI3K-Akt, eNOS and NHE activity in the ciliary epithelium. Mol Cell Endocrinol. 2006 Jul 11; 2006 Jun 9. PMID: 16764985

Cregger M, Berger AJ, Rimm DL: Immunohistochemistry and quantitative analysis of protein expression. Arch Pathol Lab Med. 2006 Jul. PMID: 16831029

Wu JJ, Roth RJ, Anderson EJ, Hong EG, Lee MK, Choi CS, Neufer PD, Shulman GI, Kim JK, Bennett AM: Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity. Cell Metab. 2006 Jul. PMID: 16814733

Kerstetter JE, Wall DE, O'Brien KO, Caseria DM, Insogna KL: Meat and soy protein affect calcium homeostasis in healthy women. J Nutr. 2006 Jul. PMID: 16772455

Galisteo ML, Yang Y, Ureña J, Schlessinger J: Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli. Proc Natl Acad Sci U S A. 2006 Jun 27; 2006 Jun 15. PMID: 16777958

Geibel J, Sritharan K, Geibel R, Geibel P, Persing JS, Seeger A, Roepke TK, Deichstetter M, Prinz C, Cheng SX, Martin D, Hebert SC: Calcium-sensing receptor abrogates secretagogue- induced increases in intestinal net fluid secretion by enhancing cyclic nucleotide destruction. Proc Natl Acad Sci U S A. 2006 Jun 20; 2006 Jun 7. PMID: 16760252

McCarthy MM, DiVito KA, Sznol M, Kovacs D, Halaban R, Berger AJ, Flaherty KT, Camp RL, Lazova R, Rimm DL, Kluger HM: Expression of tumor necrosis factor--related apoptosis-inducing ligand receptors 1 and 2 in melanoma. Clin Cancer Res. 2006 Jun 15. PMID: 16778114

Cowan JD, Rimm DL, Tuck DP: Cruella: developing a scalable tissue microarray data management system. Arch Pathol Lab Med. 2006 Jun. PMID: 16740033

Ardeshirpour L, Dann P, Pollak M, Wysolmerski J, VanHouten J: The calcium-sensing receptor regulates PTHrP production and calcium transport in the lactating mammary gland. Bone. 2006 Jun; 2005 Dec 27. PMID: 16377269

Psyrri A, Yu Z, Bamias A, Weinberger PM, Markakis S, Kowalski D, Camp RL, Rimm DL, Dimopoulos MA: Evaluation of the prognostic value of cellular inhibitor of apoptosis protein in epithelial ovarian cancer using automated quantitative protein analysis. Cancer Epidemiol Biomarkers Prev. 2006 Jun. PMID: 16775178

Hochstrasser M, Cohen R: Cecile M. Pickart 1954-2006. Nat Cell Biol. 2006 Jun. PMID: 16738698

Dolled-Filhart M, McCabe A, Giltnane J, Cregger M, Camp RL, Rimm DL: Quantitative in situ analysis of beta-catenin expression in breast cancer shows decreased expression is associated with poor outcome. Cancer Res. 2006 May 15. PMID: 16707478

Pappas DJ, Rimm DL: Direct interaction of the C-terminal domain of alpha-catenin and F-actin is necessary for stabilized cell-cell adhesion. Cell Commun Adhes. 2006 May-Jun. PMID: 16798615

Ghofrani M, Beckman D, Rimm DL: The value of onsite adequacy assessment of thyroid fine-needle aspirations is a function of operator experience. Cancer. 2006 Apr 25. PMID: 16400635

Chung GG, Yoon HH, Zerkowski MP, Ghosh S, Thomas L, Harigopal M, Charette LA, Salem RR, Camp RL, Rimm DL, Burtness BA: Vascular endothelial growth factor, FLT-1, and FLK-1 analysis in a pancreatic cancer tissue microarray. Cancer. 2006 Apr 15. PMID: 16532435

Ozcan F, Klein P, Lemmon MA, Lax I, Schlessinger J: On the nature of low- and high-affinity EGF receptors on living cells. Proc Natl Acad Sci U S A. 2006 Apr 11; 2006 Mar 29. PMID: 16571657

Turk BE, Lee DH, Yamakoshi Y, Klingenhoff A, Reichenberger E, Wright JT, Simmer JP, Komisarof JA, Cantley LC, Bartlett JD: MMP-20 is predominately a tooth-specific enzyme with a deep catalytic pocket that hydrolyzes type V collagen. Biochemistry. 2006 Mar 28. PMID: 16548514

Hua W, Sheff D, Toomre D, Mellman I: Vectorial insertion of apical and basolateral membrane proteins in polarized epithelial cells revealed by quantitative 3D live cell imaging. J Cell Biol. 2006 Mar 27. PMID: 16567501

He Y, Zhang W, Zhang R, Zhang H, Min W: SOCS1 inhibits tumor necrosis factor-induced activation of ASK1-JNK inflammatory signaling by mediating ASK1 degradation. J Biol Chem. 2006 Mar 3; 2006 Jan 5. PMID: 16407264

Furdui CM, Lew ED, Schlessinger J, Anderson KS: Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction. Mol Cell. 2006 Mar 3. PMID: 16507368

Stankewich MC, Stabach PR, Morrow JS: Human Sec31B: a family of new mammalian orthologues of yeast Sec31p that associate with the COPII coat. J Cell Sci. 2006 Mar 1. PMID: 16495487

Kreft SG, Wang L, Hochstrasser M: Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI). J Biol Chem. 2006 Feb 24; 2005 Dec 22. PMID: 16373356

Ma JL, Lee SJ, Duong JK, Stern DF: Activation of the checkpoint kinase Rad53 by the phosphatidyl inositol kinase-like kinase Mec1. J Biol Chem. 2006 Feb 17; 2005 Dec 19. PMID: 16365046

Chi H, Barry SP, Roth RJ, Wu JJ, Jones EA, Bennett AM, Flavell RA: Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses. Proc Natl Acad Sci U S A. 2006 Feb 14; 2006 Feb 6. PMID: 16461893

Uhlén P, Burch PM, Zito CI, Estrada M, Ehrlich BE, Bennett AM: Gain-of-function/Noonan syndrome SHP-2/Ptpn11 mutants enhance calcium oscillations and impair NFAT signaling. Proc Natl Acad Sci U S A. 2006 Feb 14; 2006 Feb 3. PMID: 16461457

Weinberger PM, Yu Z, Haffty BG, Kowalski D, Harigopal M, Brandsma J, Sasaki C, Joe J, Camp RL, Rimm DL, Psyrri A: Molecular classification identifies a subset of human papillomavirus--associated oropharyngeal cancers with favorable prognosis. J Clin Oncol. 2006 Feb 10; 2006 Jan 9. PMID: 16401683

Ravid T, Kreft SG, Hochstrasser M: Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways. EMBO J. 2006 Feb 8; 2006 Jan 26. PMID: 16437165

Coleman DL, Kazdin AE, Miller LA, Morrow JS, Udelsman R: Guidelines for interactions between clinical faculty and the pharmaceutical industry: one medical school's approach. Acad Med. 2006 Feb. PMID: 16436576

Li Y, Wang P, Xu J, Desir GV: Voltage-gated potassium channel Kv1.3 regulates GLUT4 trafficking to the plasma membrane via a Ca2+-dependent mechanism. Am J Physiol Cell Physiol. 2006 Feb. PMID: 16403947

Ovadia S, Insogna K, Yao GQ: The cell-surface isoform of colony stimulating factor 1 (CSF1) restores but does not completely normalize fecundity in CSF1-deficient mice. Biol Reprod. 2006 Feb; 2005 Oct 19. PMID: 16237150

Ruiz-Caro J, Basavapathruni A, Kim JT, Bailey CM, Wang L, Anderson KS, Hamilton AD, Jorgensen WL: Optimization of diarylamines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem Lett. 2006 Feb; 2005 Nov 17. PMID: 16298131

Yu W, Wu B, Lin N, Stone K, Williams K, Zhao H: Detecting and aligning peaks in mass spectrometry data with applications to MALDI. Comput Biol Chem. 2006 Feb; 2005 Nov 17. PMID: 16298163

VanHouten JN, Yu N, Rimm D, Dotto J, Arnold A, Wysolmerski JJ, Udelsman R: Hypercalcemia of malignancy due to ectopic transactivation of the parathyroid hormone gene. J Clin Endocrinol Metab. 2006 Feb; 2005 Nov 1. PMID: 16263810

Hochstrasser M: Lingering mysteries of ubiquitin-chain assembly. Cell. 2006 Jan 13. PMID: 16413479

Paek H, Kogan Y, Thomas P, Codish S, Krauthammer M: Shallow semantic parsing of randomized controlled trial reports. AMIA Annu Symp Proc. 2006. PMID: 17238412

Kerscher O, Felberbaum R, Hochstrasser M: Modification of proteins by ubiquitin and ubiquitin-like proteins. Annu Rev Cell Dev Biol. 2006. PMID: 16753028

Marius P, Guerra MT, Nathanson MH, Ehrlich BE, Leite MF: Calcium release from ryanodine receptors in the nucleoplasmic reticulum. Cell Calcium. 2006 Jan; 2005 Nov 9. PMID: 16289270

Yu W, Wu B, Liu J, Li X, Stone K, Williams KR, Zhao H: MALDI-MS data analysis for disease biomarker discovery. Methods Mol Biol. 2006. PMID: 16785651

Colangelo CM, Williams KR: Isotope-coded affinity tags for protein quantification. Methods Mol Biol. 2006. PMID: 16785647

Turk BE, Hutti JE, Cantley LC: Determining protein kinase substrate specificity by parallel solution-phase assay of large numbers of peptide substrates. Nat Protoc. 2006. PMID: 17406259

McCabe A, Dolled-Filhart M, Camp RL, Rimm DL: Automated quantitative analysis (AQUA) of in situ protein expression, antibody concentration, and prognosis. J Natl Cancer Inst. 2005 Dec 21. PMID: 16368942

Psyrri A, Kassar M, Yu Z, Bamias A, Weinberger PM, Markakis S, Kowalski D, Camp RL, Rimm DL, Dimopoulos MA: Effect of epidermal growth factor receptor expression level on survival in patients with epithelial ovarian cancer. Clin Cancer Res. 2005 Dec 15. PMID: 16361548

Li J, Young CS, Lizardi PM, Stern DF: In situ detection of specific DNA double strand breaks using rolling circle amplification. Cell Cycle. 2005 Dec; 2005 Dec 27. PMID: 16294038

Psyrri A, Bamias A, Yu Z, Weinberger PM, Kassar M, Markakis S, Kowalski D, Efstathiou E, Camp RL, Rimm DL, Dimopoulos MA: Subcellular localization and protein levels of cyclin-dependent kinase inhibitor p27 independently predict for survival in epithelial ovarian cancer. Clin Cancer Res. 2005 Dec 1. PMID: 16322299

Angeletti C, Harvey NR, Khomitch V, Fischer AH, Levenson RM, Rimm DL: Detection of malignancy in cytology specimens using spectral-spatial analysis. Lab Invest. 2005 Dec. PMID: 16200074

Ptacek J, Devgan G, Michaud G, Zhu H, Zhu X, Fasolo J, Guo H, Jona G, Breitkreutz A, Sopko R, McCartney RR, Schmidt MC, Rachidi N, Lee SJ, Mah AS, Meng L, Stark MJ, Stern DF, De Virgilio C, Tyers M, Andrews B, Gerstein M, Schweitzer B, Predki PF, Snyder M: Global analysis of protein phosphorylation in yeast. Nature. 2005 Dec 1. PMID: 16319894

Li J, Stern DF: DNA damage regulates Chk2 association with chromatin. J Biol Chem. 2005 Nov 11; 2005 Sep 8. PMID: 16150728

Toomre D: Spying on IgE receptor signaling: simply complex, or not? J Cell Biol. 2005 Nov 7. PMID: 16275748

Siddiqui SF, Pawelek J, Handerson T, Lin CY, Dickson RB, Rimm DL, Camp RL: Coexpression of beta1,6-N-acetylglucosaminyltransferase V glycoprotein substrates defines aggressive breast cancers with poor outcome. Cancer Epidemiol Biomarkers Prev. 2005 Nov. PMID: 16284372

Sehgal S, Guerra MT, Kruglov EA, Wang J, Nathanson MH: Protein 4.1N does not interact with the inositol 1,4,5-trisphosphate receptor in an epithelial cell line. Cell Calcium. 2005 Nov. PMID: 16122796

Yono M, Pouresmail M, Takahashi W, Flanagan JF, Weiss RM, Latifpour J: Effect of insulin treatment on tissue size of the genitourinary tract in BB rats with spontaneously developed and streptozotocin-induced diabetes. Naunyn Schmiedebergs Arch Pharmacol. 2005 Nov; 2005 Oct 19. PMID: 16235050

Dolled-Filhart MP, Rimm DL, Stroobant P: Quantitative in situ cancer proteomics: molecular pathology comes of age with automated tissue microarray analysis. Per Med. 2005 Nov. PMID: 29788575

Husain SZ, Prasad P, Grant WM, Kolodecik TR, Nathanson MH, Gorelick FS: The ryanodine receptor mediates early zymogen activation in pancreatitis. Proc Natl Acad Sci U S A. 2005 Oct 4; 2005 Sep 26. PMID: 16186498

Busque SM, Kerstetter JE, Geibel JP, Insogna K: L-type amino acids stimulate gastric acid secretion by activation of the calcium-sensing receptor in parietal cells. Am J Physiol Gastrointest Liver Physiol. 2005 Oct; 2005 Jun 16. PMID: 15961860

Renzulli JF 2nd, Shetty R, Mangray S, Anderson KR, Weiss RM, Caldamone AA: Clinical and histological significance of the testicular remnant found on inguinal exploration after diagnostic laparoscopy in the absence of a patent processus vaginalis. J Urol. 2005 Oct. PMID: 16148657

Minagawa N, Kruglov EA, Dranoff JA, Robert ME, Gores GJ, Nathanson MH: The anti-apoptotic protein Mcl-1 inhibits mitochondrial Ca2+ signals. J Biol Chem. 2005 Sep 30; 2005 Jul 18. PMID: 16027162

Finberg KE, Wagner CA, Bailey MA, Paunescu TG, Breton S, Brown D, Giebisch G, Geibel JP, Lifton RP: The B1-subunit of the H(+) ATPase is required for maximal urinary acidification. Proc Natl Acad Sci U S A. 2005 Sep 20; 2005 Sep 8. PMID: 16174750

Amin DN, Tuck D, Stern DF: Neuregulin-regulated gene expression in mammary carcinoma cells. Exp Cell Res. 2005 Sep 10. PMID: 15963498

Choi DH, Kim S, Rimm DL, Carter D, Haffty BG: Immunohistochemical biomarkers in patients with early-onset breast carcinoma by tissue microarray. Cancer J. 2005 Sep-Oct. PMID: 16259871

Park SY, Cho YR, Finck BN, Kim HJ, Higashimori T, Hong EG, Lee MK, Danton C, Deshmukh S, Cline GW, Wu JJ, Bennett AM, Rothermel B, Kalinowski A, Russell KS, Kim YB, Kelly DP, Kim JK: Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver. Diabetes. 2005 Sep. PMID: 16123338

Psyrri A, Yu Z, Weinberger PM, Sasaki C, Haffty B, Camp R, Rimm D, Burtness BA: Quantitative determination of nuclear and cytoplasmic epidermal growth factor receptor expression in oropharyngeal squamous cell cancer by using automated quantitative analysis. Clin Cancer Res. 2005 Aug 15. PMID: 16115926

Wang CX, Koay DC, Edwards A, Lu Z, Mor G, Ocal IT, Digiovanna MP: In vitro and in vivo effects of combination of Trastuzumab (Herceptin) and Tamoxifen in breast cancer. Breast Cancer Res Treat. 2005 Aug. PMID: 16155796

Stern DF: Phosphoproteomics for oncology discovery and treatment. Expert Opin Ther Targets. 2005 Aug. PMID: 16083347

McCarthy MM, Sznol M, DiVito KA, Camp RL, Rimm DL, Kluger HM: Evaluating the expression and prognostic value of TRAIL-R1 and TRAIL-R2 in breast cancer. Clin Cancer Res. 2005 Jul 15. PMID: 16033835

Kluger HM, Chelouche Lev D, Kluger Y, McCarthy MM, Kiriakova G, Camp RL, Rimm DL, Price JE: Using a xenograft model of human breast cancer metastasis to find genes associated with clinically aggressive disease. Cancer Res. 2005 Jul 1. PMID: 15994930

Gulcicek EE, Colangelo CM, McMurray W, Stone K, Williams K, Wu T, Zhao H, Spratt H, Kurosky A, Wu B: Proteomics and the analysis of proteomic data: an overview of current protein-profiling technologies. Curr Protoc Bioinformatics. 2005 Jul. PMID: 18428746

Hens JR, Wilson KM, Dann P, Chen X, Horowitz MC, Wysolmerski JJ: TOPGAL mice show that the canonical Wnt signaling pathway is active during bone development and growth and is activated by mechanical loading in vitro. J Bone Miner Res. 2005 Jul; 2005 Feb 14. PMID: 15940363

Moresco EM, Donaldson S, Williamson A, Koleske AJ: Integrin-mediated dendrite branch maintenance requires Abelson (Abl) family kinases. J Neurosci. 2005 Jun 29. PMID: 15987940

Zhang R, Luo D, Miao R, Bai L, Ge Q, Sessa WC, Min W: Hsp90-Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis. Oncogene. 2005 Jun 2. PMID: 15782121

Vidyasagar S, Barmeyer C, Geibel J, Binder HJ, Rajendran VM: Role of short-chain fatty acids in colonic HCO(3) secretion. Am J Physiol Gastrointest Liver Physiol. 2005 Jun; 2005 Jan 27. PMID: 15677553

Harigopal M, Berger AJ, Camp RL, Rimm DL, Kluger HM: Automated quantitative analysis of E-cadherin expression in lymph node metastases is predictive of survival in invasive ductal breast cancer. Clin Cancer Res. 2005 Jun 1. PMID: 15930343

Desir GV: Kv1.3 potassium channel blockade as an approach to insulin resistance. Expert Opin Ther Targets. 2005 Jun. PMID: 15948674

Wu JJ, Zhang L, Bennett AM: The noncatalytic amino terminus of mitogen-activated protein kinase phosphatase 1 directs nuclear targeting and serum response element transcriptional regulation. Mol Cell Biol. 2005 Jun. PMID: 15899879

Zhang W, Zheng S, Storz P, Min W: Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor. J Biol Chem. 2005 May 13; 2005 Mar 8. PMID: 15755722

Xu J, Li G, Wang P, Velazquez H, Yao X, Li Y, Wu Y, Peixoto A, Crowley S, Desir GV: Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure. J Clin Invest. 2005 May; 2005 Apr 7. PMID: 15841207

Fadare O, Mariappan MR, Hileeto D, Wang S, McAlpine JN, Rimm DL: Upstaging based solely on positive peritoneal washing does not affect outcome in endometrial cancer. Mod Pathol. 2005 May. PMID: 15578078

Wu JJ, Bennett AM: Essential role for mitogen-activated protein (MAP) kinase phosphatase-1 in stress-responsive MAP kinase and cell survival signaling. J Biol Chem. 2005 Apr 22; 2005 Feb 17. PMID: 15722358

Li X, Zhang R, Luo D, Park SJ, Wang Q, Kim Y, Min W: Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation. J Biol Chem. 2005 Apr 15; 2005 Feb 8. PMID: 15701637

Provost E, McCabe A, Stern J, Lizardi I, D'Aquila TG, Rimm DL: Functional correlates of mutation of the Asp32 and Gly34 residues of beta-catenin. Oncogene. 2005 Apr 14. PMID: 15829978

Gong LW, Di Paolo G, Diaz E, Cestra G, Diaz ME, Lindau M, De Camilli P, Toomre D: Phosphatidylinositol phosphate kinase type I gamma regulates dynamics of large dense-core vesicle fusion. Proc Natl Acad Sci U S A. 2005 Apr 5; 2005 Mar 25. PMID: 15793002

Tsvetkov LM, Tsekova RT, Xu X, Stern DF: The Plk1 Polo box domain mediates a cell cycle and DNA damage regulated interaction with Chk2. Cell Cycle. 2005 Apr; 2005 Apr 9. PMID: 15876876

Knopp E, Troiano N, Bouxsein M, Sun BH, Lostritto K, Gundberg C, Dziura J, Insogna K: The effect of aging on the skeletal response to intermittent treatment with parathyroid hormone. Endocrinology. 2005 Apr; 2004 Dec 23. PMID: 15618351

Binder HJ, Rajendran V, Sadasivan V, Geibel JP: Bicarbonate secretion: a neglected aspect of colonic ion transport. J Clin Gastroenterol. 2005 Apr. PMID: 15758660

DeMauro S, Wysolmerski J: Hypercalcemia in breast cancer: an echo of bone mobilization during lactation? J Mammary Gland Biol Neoplasia. 2005 Apr. PMID: 16025222

Li J, Stern DF: Regulation of CHK2 by DNA-dependent protein kinase. J Biol Chem. 2005 Mar 25; 2005 Jan 24. PMID: 15668230

Tsvetkov L, Stern DF: Interaction of chromatin-associated Plk1 and Mcm7. J Biol Chem. 2005 Mar 25; 2005 Jan 15. PMID: 15654075

DiGiovanna MP, Stern DF, Edgerton SM, Whalen SG, Moore D 2nd, Thor AD: Relationship of epidermal growth factor receptor expression to ErbB-2 signaling activity and prognosis in breast cancer patients. J Clin Oncol. 2005 Feb 20. PMID: 15718311

Hannich JT, Lewis A, Kroetz MB, Li SJ, Heide H, Emili A, Hochstrasser M: Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J Biol Chem. 2005 Feb 11; 2004 Dec 6. PMID: 15590687

Yu Z, Weinberger PM, Haffty BG, Sasaki C, Zerillo C, Joe J, Kowalski D, Dziura J, Camp RL, Rimm DL, Psyrri A: Cyclin d1 is a valuable prognostic marker in oropharyngeal squamous cell carcinoma. Clin Cancer Res. 2005 Feb 1. PMID: 15709184

Carpenter TO, Ellis BK, Insogna KL, Philbrick WM, Sterpka J, Shimkets R: Fibroblast growth factor 7: an inhibitor of phosphate transport derived from oncogenic osteomalacia-causing tumors. J Clin Endocrinol Metab. 2005 Feb; 2004 Nov 23. PMID: 15562028

Wheeler MA, Ayyagari RR, Wheeler GL, Weiss RM: Regulation of cyclic nucleotides in the urinary tract. J Smooth Muscle Res. 2005 Feb. PMID: 15855736

Cestra G, Toomre D, Chang S, De Camilli P: The Abl/Arg substrate ArgBP2/nArgBP2 coordinates the function of multiple regulatory mechanisms converging on the actin cytoskeleton. Proc Natl Acad Sci U S A. 2005 Feb 1; 2005 Jan 19. PMID: 15659545

Hoffman JF, Geibel JP: Fluorescent imaging of Cl- in Amphiuma red blood cells: how the nuclear exclusion of Cl- affects the plasma membrane potential. Proc Natl Acad Sci U S A. 2005 Jan 18; 2005 Jan 6. PMID: 15637151

Shifman MA, Sun K, Colangelo CM, Cheung KH, Miller P, Williams K: YPED: a proteomics database for protein expression analysis. AMIA Annu Symp Proc. 2005. PMID: 16779398

Kogan Y, Collier N, Pakhomov S, Krauthammer M: Towards semantic role labeling & IE in the medical literature. AMIA Annu Symp Proc. 2005. PMID: 16779072

Geibel JP: Secretion and absorption by colonic crypts. Annu Rev Physiol. 2005. PMID: 15709966

Higgins SA, Matloff ET, Rimm DL, Dziura J, Haffty BG, King BL: Patterns of reduced nipple aspirate fluid production and ductal lavage cellularity in women at high risk for breast cancer. Breast Cancer Res. 2005; 2005 Oct 24. PMID: 16280052

Hens JR, Wysolmerski JJ: Key stages of mammary gland development: molecular mechanisms involved in the formation of the embryonic mammary gland. Breast Cancer Res. 2005; 2005 Aug 10. PMID: 16168142

Tsvetkov L, Stern DF: Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage. Cell Cycle. 2005 Jan; 2005 Jan 5. PMID: 15611664

Eisenberg ML, Maker AV, Slezak LA, Nathan JD, Sritharan KC, Jena BP, Geibel JP, Andersen DK: Insulin receptor (IR) and glucose transporter 2 (GLUT2) proteins form a complex on the rat hepatocyte membrane. Cell Physiol Biochem. 2005. PMID: 15665515

Carriero N, Osier MV, Cheung KH, Miller PL, Gerstein M, Zhao H, Wu B, Rifkin S, Chang J, Zhang H, White K, Williams K, Schultz M: A high productivity/low maintenance approach to high-performance computation for biomedicine: four case studies. J Am Med Inform Assoc. 2005 Jan-Feb; 2004 Oct 18. PMID: 15492032

Hadjidemetriou S, Toomre D, Duncan JS: Segmentation and 3D reconstruction of microtubules in total internal reflection fluorescence microscopy (TIRFM). Med Image Comput Comput Assist Interv. 2005. PMID: 16685915

Hebert SC, Desir G, Giebisch G, Wang W: Molecular diversity and regulation of renal potassium channels. Physiol Rev. 2005 Jan. PMID: 15618483

Cherniske EM, Carpenter TO, Klaiman C, Young E, Bregman J, Insogna K, Schultz RT, Pober BR: Multisystem study of 20 older adults with Williams syndrome. Am J Med Genet A. 2004 Dec 15. PMID: 15534874

Jackson-Fisher AJ, Bellinger G, Ramabhadran R, Morris JK, Lee KF, Stern DF: ErbB2 is required for ductal morphogenesis of the mammary gland. Proc Natl Acad Sci U S A. 2004 Dec 7; 2004 Nov 29. PMID: 15569931

Koullias GJ, Ravichandran P, Korkolis DP, Rimm DL, Elefteriades JA: Increased tissue microarray matrix metalloproteinase expression favors proteolysis in thoracic aortic aneurysms and dissections. Ann Thorac Surg. 2004 Dec. PMID: 15561045

Divito KA, Berger AJ, Camp RL, Dolled-Filhart M, Rimm DL, Kluger HM: Automated quantitative analysis of tissue microarrays reveals an association between high Bcl-2 expression and improved outcome in melanoma. Cancer Res. 2004 Dec 1. PMID: 15574790

Berger AJ, Camp RL, Divito KA, Kluger HM, Halaban R, Rimm DL: Automated quantitative analysis of HDM2 expression in malignant melanoma shows association with early-stage disease and improved outcome. Cancer Res. 2004 Dec 1. PMID: 15574789

Krauthammer M, Nenadic G: Term identification in the biomedical literature. J Biomed Inform. 2004 Dec. PMID: 15542023

Lee SJ, Duong JK, Stern DF: A Ddc2-Rad53 fusion protein can bypass the requirements for RAD9 and MRC1 in Rad53 activation. Mol Biol Cell. 2004 Dec; 2004 Sep 29. PMID: 15456903

Giltnane JM, Rimm DL: Technology insight: Identification of biomarkers with tissue microarray technology. Nat Clin Pract Oncol. 2004 Dec. PMID: 16264828

Amerik AY, Hochstrasser M: Mechanism and function of deubiquitinating enzymes. Biochim Biophys Acta. 2004 Nov 29. PMID: 15571815

Schlessinger J: Common and distinct elements in cellular signaling via EGF and FGF receptors. Science. 2004 Nov 26. PMID: 15567848

Mattoon DR, Lamothe B, Lax I, Schlessinger J: The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway. BMC Biol. 2004 Nov 18; 2004 Nov 18. PMID: 15550174

Camp RL, Dolled-Filhart M, Rimm DL: X-tile: a new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization. Clin Cancer Res. 2004 Nov 1. PMID: 15534099

Stone KL, Williams KR: Enzymatic digestion of proteins in gels for mass spectrometric identification and structural analysis. Curr Protoc Protein Sci. 2004 Nov. PMID: 18429249

Chauvet V, Tian X, Husson H, Grimm DH, Wang T, Hiesberger T, Igarashi P, Bennett AM, Ibraghimov-Beskrovnaya O, Somlo S, Caplan MJ: Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus. J Clin Invest. 2004 Nov. PMID: 15545994

Ravid T, Hochstrasser M: NF-kappaB signaling: flipping the switch with polyubiquitin chains. Curr Biol. 2004 Oct 26. PMID: 15498483

Zhang H, Zhang R, Luo Y, D'Alessio A, Pober JS, Min W: AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation. J Biol Chem. 2004 Oct 22; 2004 Aug 13. PMID: 15310755

Cline GW, Lepine RL, Papas KK, Kibbey RG, Shulman GI: 13C NMR isotopomer analysis of anaplerotic pathways in INS-1 cells. J Biol Chem. 2004 Oct 22; 2004 Aug 9. PMID: 15304488

Stern DF: More than a marker... Phosphorylated Akt in prostate carcinoma. Clin Cancer Res. 2004 Oct 1. PMID: 15475426

Correa PR, Guerra MT, Leite MF, Spray DC, Nathanson MH: Endotoxin unmasks the role of gap junctions in the liver. Biochem Biophys Res Commun. 2004 Sep 24. PMID: 15336523

Fidzinski P, Salvador-Silva M, Choritz L, Geibel J, Coca-Prados M: Inhibition of NHE-1 Na+/H+ exchanger by natriuretic peptides in ocular nonpigmented ciliary epithelium. Am J Physiol Cell Physiol. 2004 Sep; 2004 May 12. PMID: 15140751

Xu X, Lee J, Stern DF: Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1. J Biol Chem. 2004 Aug 13; 2004 Jun 25. PMID: 15220350

Hoek K, Rimm DL, Williams KR, Zhao H, Ariyan S, Lin A, Kluger HM, Berger AJ, Cheng E, Trombetta ES, Wu T, Niinobe M, Yoshikawa K, Hannigan GE, Halaban R: Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas. Cancer Res. 2004 Aug 1. PMID: 15289333

Kang WS, Tamarkin FJ, Wheeler MA, Weiss RM: Rapid up-regulation of endothelial nitric-oxide synthase in a mouse model of Escherichia coli lipopolysaccharide-induced bladder inflammation. J Pharmacol Exp Ther. 2004 Aug; 2004 Apr 13. PMID: 15082754

DiVito KA, Charette LA, Rimm DL, Camp RL: Long-term preservation of antigenicity on tissue microarrays. Lab Invest. 2004 Aug. PMID: 15195116

Calderwood DA, Tai V, Di Paolo G, De Camilli P, Ginsberg MH: Competition for talin results in trans-dominant inhibition of integrin activation. J Biol Chem. 2004 Jul 9; 2004 May 13. PMID: 15143061

Kolli S, Zito CI, Mossink MH, Wiemer EA, Bennett AM: The major vault protein is a novel substrate for the tyrosine phosphatase SHP-2 and scaffold protein in epidermal growth factor signaling. J Biol Chem. 2004 Jul 9; 2004 May 7. PMID: 15133037

Angeletti C, Khomitch V, Halaban R, Rimm DL: Novel tyramide-based tyrosinase assay for the detection of melanoma cells in cytological preparations. Diagn Cytopathol. 2004 Jul. PMID: 15236262

Lamothe B, Yamada M, Schaeper U, Birchmeier W, Lax I, Schlessinger J: The docking protein Gab1 is an essential component of an indirect mechanism for fibroblast growth factor stimulation of the phosphatidylinositol 3-kinase/Akt antiapoptotic pathway. Mol Cell Biol. 2004 Jul. PMID: 15199124

Yang X, Yu K, Hao Y, Li DM, Stewart R, Insogna KL, Xu T: LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1. Nat Cell Biol. 2004 Jul; 2004 Jun 27. PMID: 15220930

Cheung KH, Hager J, Pan D, Srivastava R, Mane S, Li Y, Miller P, Williams KR: KARMA: a web server application for comparing and annotating heterogeneous microarray platforms. Nucleic Acids Res. 2004 Jul 1. PMID: 15215426

Jaganath R, Angeletti C, Levenson R, Rimm DL: Diagnostic classification of urothelial cells in urine cytology specimens using exclusively spectral information. Cancer. 2004 Jun 25. PMID: 15211478

Fadare O, Mariappan MR, Wang S, Hileeto D, McAlpine J, Rimm DL: The histologic subtype of ovarian tumors affects the detection rate by pelvic washings. Cancer. 2004 Jun 25. PMID: 15211473

Zhang R, Al-Lamki R, Bai L, Streb JW, Miano JM, Bradley J, Min W: Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner. Circ Res. 2004 Jun 11; 2004 Apr 29. PMID: 15117824

Kluger HM, DiVito K, Berger AJ, Halaban R, Ariyan S, Camp RL, Rimm DL: Her2/neu is not a commonly expressed therapeutic target in melanoma -- a large cohort tissue microarray study. Melanoma Res. 2004 Jun. PMID: 15179190

Kontaridis MI, Eminaga S, Fornaro M, Zito CI, Sordella R, Settleman J, Bennett AM: SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway. Mol Cell Biol. 2004 Jun. PMID: 15169898

Chung GG, Zerkowski MP, Ocal IT, Dolled-Filhart M, Kang JY, Psyrri A, Camp RL, Rimm DL: beta-Catenin and p53 analyses of a breast carcinoma tissue microarray. Cancer. 2004 May 15. PMID: 15139049

Miller AL, Wang Y, Mooseker MS, Koleske AJ: The Abl-related gene (Arg) requires its F-actin-microtubule cross-linking activity to regulate lamellipodial dynamics during fibroblast adhesion. J Cell Biol. 2004 May 10. PMID: 15138293

He CY, Ho HH, Malsam J, Chalouni C, West CM, Ullu E, Toomre D, Warren G: Golgi duplication in Trypanosoma brucei. J Cell Biol. 2004 May 10. PMID: 15138289

Pradhan D, Tseng K, Cianci CD, Morrow JS: Antibodies to betaISigma2 spectrin identify in-homogeneities in the erythrocyte membrane skeleton. Blood Cells Mol Dis. 2004 May-Jun. PMID: 15121100

Ivins Zito C, Kontaridis MI, Fornaro M, Feng GS, Bennett AM: SHP-2 regulates the phosphatidylinositide 3'-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis. J Cell Physiol. 2004 May. PMID: 15040005

Gotoh N, Laks S, Nakashima M, Lax I, Schlessinger J: FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts. FEBS Lett. 2004 Apr 23. PMID: 15094036

Hernández SE, Settleman J, Koleske AJ: Adhesion-dependent regulation of p190RhoGAP in the developing brain by the Abl-related gene tyrosine kinase. Curr Biol. 2004 Apr 20. PMID: 15084284

Xu J, Wang P, Li Y, Li G, Kaczmarek LK, Wu Y, Koni PA, Flavell RA, Desir GV: The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity. Proc Natl Acad Sci U S A. 2004 Mar 2; 2004 Feb 23. PMID: 14981264

Hebert SC, Cheng S, Geibel J: Functions and roles of the extracellular Ca2+-sensing receptor in the gastrointestinal tract. Cell Calcium. 2004 Mar. PMID: 15200147

Amin DN, Perkins AS, Stern DF: Gene expression profiling of ErbB receptor and ligand-dependent transcription. Oncogene. 2004 Feb 19. PMID: 14973552

Argiris A, Wang CX, Whalen SG, DiGiovanna MP: Synergistic interactions between tamoxifen and trastuzumab (Herceptin). Clin Cancer Res. 2004 Feb 15. PMID: 14977844

Calderwood DA: Integrin activation. J Cell Sci. 2004 Feb 15. PMID: 14754902

Velichutina I, Connerly PL, Arendt CS, Li X, Hochstrasser M: Plasticity in eucaryotic 20S proteasome ring assembly revealed by a subunit deletion in yeast. EMBO J. 2004 Feb 11; 2004 Jan 22. PMID: 14739934

VanHouten J, Dann P, McGeoch G, Brown EM, Krapcho K, Neville M, Wysolmerski JJ: The calcium-sensing receptor regulates mammary gland parathyroid hormone-related protein production and calcium transport. J Clin Invest. 2004 Feb. PMID: 14966569

Yono M, Latifpour J, Takahashi W, Pouresmail M, Afiatpour P, Weiss RM: Age-related changes in the properties of the endothelin receptor system at protein and mRNA levels in the rat vas deferens. J Recept Signal Transduct Res. 2004 Feb. PMID: 15344879

Gallagher PG, Zhang Z, Morrow JS, Forget BG: Mutation of a highly conserved isoleucine disrupts hydrophobic interactions in the alpha beta spectrin self-association binding site. Lab Invest. 2004 Feb. PMID: 14661034

Klein P, Mattoon D, Lemmon MA, Schlessinger J: A structure-based model for ligand binding and dimerization of EGF receptors. Proc Natl Acad Sci U S A. 2004 Jan 27; 2004 Jan 19. PMID: 14732694

Mattoon D, Klein P, Lemmon MA, Lax I, Schlessinger J: The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function. Proc Natl Acad Sci U S A. 2004 Jan 27; 2004 Jan 19. PMID: 14732693

Haffty BG, Hauser A, Choi DH, Parisot N, Rimm D, King B, Carter D: Molecular markers for prognosis after isolated postmastectomy chest wall recurrence. Cancer. 2004 Jan 15. PMID: 14716758

Golden LH, Insogna KL: The expanding role of PI3-kinase in bone. Bone. 2004 Jan. PMID: 14751558

Kluger HM, Dolled-Filhart M, Rodov S, Kacinski BM, Camp RL, Rimm DL: Macrophage colony-stimulating factor-1 receptor expression is associated with poor outcome in breast cancer by large cohort tissue microarray analysis. Clin Cancer Res. 2004 Jan 1. PMID: 14734466

Cheng SX, Geibel JP, Hebert SC: Extracellular polyamines regulate fluid secretion in rat colonic crypts via the extracellular calcium-sensing receptor. Gastroenterology. 2004 Jan. PMID: 14699496

Williams K, Wu T, Colangelo C, Nairn AC: Recent advances in neuroproteomics and potential application to studies of drug addiction. Neuropharmacology. 2004. PMID: 15464134

Hernández SE, Krishnaswami M, Miller AL, Koleske AJ: How do Abl family kinases regulate cell shape and movement? Trends Cell Biol. 2004 Jan. PMID: 14729179

Zhang R, Xu Y, Ekman N, Wu Z, Wu J, Alitalo K, Min W: Etk/Bmx transactivates vascular endothelial growth factor 2 and recruits phosphatidylinositol 3-kinase to mediate the tumor necrosis factor-induced angiogenic pathway. J Biol Chem. 2003 Dec 19; 2003 Oct 7. PMID: 14532277

Kirchhoff P, Wagner CA, Gaetzschmann F, Radebold K, Geibel JP: Demonstration of a functional apical sodium hydrogen exchanger in isolated rat gastric glands. Am J Physiol Gastrointest Liver Physiol. 2003 Dec; 2003 Aug 7. PMID: 12907430

Berger AJ, Kluger HM, Li N, Kielhorn E, Halaban R, Ronai Z, Rimm DL: Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival. Cancer Res. 2003 Dec 1. PMID: 14678960

Stehberger PA, Schulz N, Finberg KE, Karet FE, Giebisch G, Lifton RP, Geibel JP, Wagner CA: Localization and regulation of the ATP6V0A4 (a4) vacuolar H+-ATPase subunit defective in an inherited form of distal renal tubular acidosis. J Am Soc Nephrol. 2003 Dec. PMID: 14638902

VanHouten JN, Dann P, Stewart AF, Watson CJ, Pollak M, Karaplis AC, Wysolmerski JJ: Mammary-specific deletion of parathyroid hormone-related protein preserves bone mass during lactation. J Clin Invest. 2003 Nov. PMID: 14597768

Finberg KE, Wagner CA, Stehberger PA, Geibel JP, Lifton RP: Molecular cloning and characterization of Atp6v1b1, the murine vacuolar H+ -ATPase B1-subunit. Gene. 2003 Oct 30. PMID: 14585495

Ikuma M, Geibel J, Binder HJ, Rajendran VM: Characterization of Cl-HCO3 exchange in basolateral membrane of rat distal colon. Am J Physiol Cell Physiol. 2003 Oct; 2003 Jun 25. PMID: 12826602

Moresco EM, Koleske AJ: Regulation of neuronal morphogenesis and synaptic function by Abl family kinases. Curr Opin Neurobiol. 2003 Oct. PMID: 14630215

Xu X, Stern DF: NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors. FASEB J. 2003 Oct. PMID: 14519663

Shibao K, Hirata K, Robert ME, Nathanson MH: Loss of inositol 1,4,5-trisphosphate receptors from bile duct epithelia is a common event in cholestasis. Gastroenterology. 2003 Oct. PMID: 14517800

Laney JD, Hochstrasser M: Ubiquitin-dependent degradation of the yeast Mat(alpha)2 repressor enables a switch in developmental state. Genes Dev. 2003 Sep 15; 2003 Sep 2. PMID: 12952895

Wu B, Abbott T, Fishman D, McMurray W, Mor G, Stone K, Ward D, Williams K, Zhao H: Comparison of statistical methods for classification of ovarian cancer using mass spectrometry data. Bioinformatics. 2003 Sep 1. PMID: 12967959

Lee SJ, Schwartz MF, Duong JK, Stern DF: Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling. Mol Cell Biol. 2003 Sep. PMID: 12917350

Provost E, Yamamoto Y, Lizardi I, Stern J, D'Aquila TG, Gaynor RB, Rimm DL: Functional correlates of mutations in beta-catenin exon 3 phosphorylation sites. J Biol Chem. 2003 Aug 22; 2003 Jun 10. PMID: 12799363

Yao GQ, Wu JJ, Sun BH, Troiano N, Mitnick MA, Insogna K: The cell surface form of colony-stimulating factor-1 is biologically active in bone in vivo. Endocrinology. 2003 Aug. PMID: 12865350

Schlessinger J, Lemmon MA: SH2 and PTB domains in tyrosine kinase signaling. Sci STKE. 2003 Jul 15; 2003 Jul 15. PMID: 12865499

Schwartz MF, Lee SJ, Duong JK, Eminaga S, Stern DF: FHA domain-mediated DNA checkpoint regulation of Rad53. Cell Cycle. 2003 Jul-Aug. PMID: 12851493

Hausladen DA, Wheeler MA, Altieri DC, Colberg JW, Weiss RM: Effect of intravesical treatment of transitional cell carcinoma with bacillus Calmette-Guerin and mitomycin C on urinary survivin levels and outcome. J Urol. 2003 Jul. PMID: 12796695

Sheryka E, Wheeler MA, Hausladen DA, Weiss RM: Urinary interleukin-8 levels are elevated in subjects with transitional cell carcinoma. Urology. 2003 Jul. PMID: 12837459

Tanis KQ, Veach D, Duewel HS, Bornmann WG, Koleske AJ: Two distinct phosphorylation pathways have additive effects on Abl family kinase activation. Mol Cell Biol. 2003 Jun. PMID: 12748290

Schwartz DC, Hochstrasser M: A superfamily of protein tags: ubiquitin, SUMO and related modifiers. Trends Biochem Sci. 2003 Jun. PMID: 12826404

Koleske AJ: Do filopodia enable the growth cone to find its way? Sci STKE. 2003 May 20; 2003 May 20. PMID: 12759482

Schlessinger J: Signal transduction. Autoinhibition control. Science. 2003 May 2. PMID: 12730587

Kim S, Rimm D, Carter D, Khan A, Parisot N, Franco MA, Bale A, Haffty BG: BRCA status, molecular markers, and clinical variables in early, conservatively managed breast cancer. Breast J. 2003 May-Jun. PMID: 12752624

Echevarría W, Leite MF, Guerra MT, Zipfel WR, Nathanson MH: Regulation of calcium signals in the nucleus by a nucleoplasmic reticulum. Nat Cell Biol. 2003 May. PMID: 12717445

Afiatpour P, Latifpour J, Takahashi W, Yono M, Foster HE Jr, Ikeda K, Pouresmail M, Weiss RM: Developmental changes in the functional, biochemical and molecular properties of rat bladder endothelin receptors. Naunyn Schmiedebergs Arch Pharmacol. 2003 May; 2003 Apr 17. PMID: 12700883

Tolgay Ocal I, Dolled-Filhart M, D'Aquila TG, Camp RL, Rimm DL: Tissue microarray-based studies of patients with lymph node negative breast carcinoma show that met expression is associated with worse outcome but is not correlated with epidermal growth factor family receptors. Cancer. 2003 Apr 15. PMID: 12673709

Camp RL, Dolled-Filhart M, King BL, Rimm DL: Quantitative analysis of breast cancer tissue microarrays shows that both high and normal levels of HER2 expression are associated with poor outcome. Cancer Res. 2003 Apr 1. PMID: 12670887

King BL, Tsai SC, Gryga ME, D'Aquila TG, Seelig SA, Morrison LE, Jacobson KK, Legator MS, Ward DC, Rimm DL, Phillips RF: Detection of chromosomal instability in paired breast surgery and ductal lavage specimens by interphase fluorescence in situ hybridization. Clin Cancer Res. 2003 Apr. PMID: 12684427

Li SJ, Hochstrasser M: The Ulp1 SUMO isopeptidase: distinct domains required for viability, nuclear envelope localization, and substrate specificity. J Cell Biol. 2003 Mar 31; 2003 Mar 24. PMID: 12654900

Stern DF: ErbBs in mammary development. Exp Cell Res. 2003 Mar 10. PMID: 12648468

Xu X, Stern DF: NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways. J Biol Chem. 2003 Mar 7; 2002 Dec 23. PMID: 12499369

Tsvetkov L, Xu X, Li J, Stern DF: Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody. J Biol Chem. 2003 Mar 7; 2002 Dec 18. PMID: 12493754

Kang JY, Dolled-Filhart M, Ocal IT, Singh B, Lin CY, Dickson RB, Rimm DL, Camp RL: Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer. Cancer Res. 2003 Mar 1. PMID: 12615728

Xu J, Koni PA, Wang P, Li G, Kaczmarek L, Wu Y, Li Y, Flavell RA, Desir GV: The voltage-gated potassium channel Kv1.3 regulates energy homeostasis and body weight. Hum Mol Genet. 2003 Mar 1. PMID: 12588802

Moresco EM, Scheetz AJ, Bornmann WG, Koleske AJ, Fitzsimonds RM: Abl family nonreceptor tyrosine kinases modulate short-term synaptic plasticity. J Neurophysiol. 2003 Mar. PMID: 12626632

Nedrelow JH, Cianci CD, Morrow JS: c-Src binds alpha II spectrin's Src homology 3 (SH3) domain and blocks calpain susceptibility by phosphorylating Tyr1176. J Biol Chem. 2003 Feb 28; 2002 Nov 20. PMID: 12446661

Kielhorn E, Provost E, Olsen D, D'Aquila TG, Smith BL, Camp RL, Rimm DL: Tissue microarray-based analysis shows phospho-beta-catenin expression in malignant melanoma is associated with poor outcome. Int J Cancer. 2003 Feb 20. PMID: 12494474

Dolled-Filhart M, Camp RL, Kowalski DP, Smith BL, Rimm DL: Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis. Clin Cancer Res. 2003 Feb. PMID: 12576423

Lang K, Wagner C, Haddad G, Burnekova O, Geibel J: Intracellular pH activates membrane-bound Na(+)/H(+) exchanger and vacuolar H(+)-ATPase in human embryonic kidney (HEK) cells. Cell Physiol Biochem. 2003. PMID: 14586169

Greenbaum D, Colangelo C, Williams K, Gerstein M: Comparing protein abundance and mRNA expression levels on a genomic scale. Genome Biol. 2003; 2003 Aug 29. PMID: 12952525

Yao X, Tian S, Chan HY, Biemesderfer D, Desir GV: Expression of KCNA10, a voltage-gated K channel, in glomerular endothelium and at the apical membrane of the renal proximal tubule. J Am Soc Nephrol. 2002 Dec. PMID: 12444201

Wagner CA, Finberg KE, Stehberger PA, Lifton RP, Giebisch GH, Aronson PS, Geibel JP: Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-base status. Kidney Int. 2002 Dec. PMID: 12427135

Curristin SM, Cao A, Stewart WB, Zhang H, Madri JA, Morrow JS, Ment LR: Disrupted synaptic development in the hypoxic newborn brain. Proc Natl Acad Sci U S A. 2002 Nov 26; 2002 Nov 15. PMID: 12438650

DiGiovanna MP, Chu P, Davison TL, Howe CL, Carter D, Claus EB, Stern DF: Active signaling by HER-2/neu in a subpopulation of HER-2/neu-overexpressing ductal carcinoma in situ: clinicopathological correlates. Cancer Res. 2002 Nov 15. PMID: 12438265

Digiovanna MP, Stern DF, Roussel RR: Production of antibodies that recognize specific tyrosine-phosphorylated peptides. Curr Protoc Immunol. 2002 Nov. PMID: 18432869

Laney JD, Hochstrasser M: Analysis of protein ubiquitination. Curr Protoc Protein Sci. 2002 Nov. PMID: 18429222

Insogna K, Mitnick M, Pascarella J, Nakchbandi I, Grey A, Masiukiewicz U: Role of the interleukin-6/interleukin-6 soluble receptor cytokine system in mediating increased skeletal sensitivity to parathyroid hormone in perimenopausal women. J Bone Miner Res. 2002 Nov. PMID: 12412787

Nakchbandi IA, Mitnick MA, Lang R, Gundberg C, Kinder B, Insogna K: Circulating levels of interleukin-6 soluble receptor predict rates of bone loss in patients with primary hyperparathyroidism. J Clin Endocrinol Metab. 2002 Nov. PMID: 12414855

Harroch S, Furtado GC, Brueck W, Rosenbluth J, Lafaille J, Chao M, Buxbaum JD, Schlessinger J: A critical role for the protein tyrosine phosphatase receptor type Z in functional recovery from demyelinating lesions. Nat Genet. 2002 Nov; 2002 Sep 30. PMID: 12355066

Camp RL, Chung GG, Rimm DL: Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat Med. 2002 Nov; 2002 Oct 21. PMID: 12389040

Ernst LM, Rimm DL: Quantitative examination of mechanophysical tumor cell enrichment in fine-needle aspiration specimens. Cancer. 2002 Oct 25. PMID: 12378594

Hochstrasser M: Molecular biology. New proteases in a ubiquitin stew. Science. 2002 Oct 18. PMID: 12386321

Walsh SA, Weiss RM: Case report: persistent dysuria and a suprapubic mass in a 3-year-old boy. Curr Opin Pediatr. 2002 Oct. PMID: 12352261

Cheung KH, Hager J, Nelson K, White K, Li Y, Snyder M, Williams K, Miller P: A dynamic approach to mapping coordinates between microplates and microarrays. J Biomed Inform. 2002 Oct-Dec. PMID: 12968779

Wheeler MA, Hausladen DA, Yoon JH, Weiss RM: Prostaglandin E2 production and cyclooxygenase-2 induction in human urinary tract infections and bladder cancer. J Urol. 2002 Oct. PMID: 12352459

Lax I, Wong A, Lamothe B, Lee A, Frost A, Hawes J, Schlessinger J: The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors. Mol Cell. 2002 Oct. PMID: 12419216

Schlessinger J: Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell. 2002 Sep 20. PMID: 12297041

Dillon DA, Hipolito E, Zheng K, Rimm DL, Costa JC: p53 mutations as tumor markers in fine needle aspirates of palpable breast masses. Acta Cytol. 2002 Sep-Oct. PMID: 12365217

Pradhan D, Morrow J: The spectrin-ankyrin skeleton controls CD45 surface display and interleukin-2 production. Immunity. 2002 Sep. PMID: 12354383

Yono M, Takahashi W, Pouresmail M, Johnson DR, Foster HE Jr, Weiss RM, Latifpour J: Quantification of endothelins, their receptors, and endothelin-converting enzyme mRNAs in rat genitourinary tract using real-time RT-PCR. J Pharmacol Toxicol Methods. 2002 Sep-Oct. PMID: 14565565

Chow A, Toomre D, Garrett W, Mellman I: Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature. 2002 Aug 29. PMID: 12198549

King BL, Crisi GM, Tsai SC, Haffty BG, Phillips RF, Rimm DL: Immunocytochemical analysis of breast cells obtained by ductal lavage. Cancer. 2002 Aug 25. PMID: 12209667

Hirata K, Dufour JF, Shibao K, Knickelbein R, O'Neill AF, Bode HP, Cassio D, St-Pierre MV, Larusso NF, Leite MF, Nathanson MH: Regulation of Ca(2+) signaling in rat bile duct epithelia by inositol 1,4,5-trisphosphate receptor isoforms. Hepatology. 2002 Aug. PMID: 12143036

Schlessinger J: All signaling is local? Mol Cell. 2002 Aug. PMID: 12191465

Pelletier L, Stern CA, Pypaert M, Sheff D, Ngô HM, Roper N, He CY, Hu K, Toomre D, Coppens I, Roos DS, Joiner KA, Warren G: Golgi biogenesis in Toxoplasma gondii. Nature. 2002 Aug 1. PMID: 12152082

Takahashi W, Afiatpour P, Jr Foster HE, Ikeda K, Wada Y, Weiss RM, Latifpour J: The effect of castration on endothelins, their receptors and endothelin converting enzyme in rat prostate. Naunyn Schmiedebergs Arch Pharmacol. 2002 Aug; 2002 May 24. PMID: 12122504

Pusl T, Wu JJ, Zimmerman TL, Zhang L, Ehrlich BE, Berchtold MW, Hoek JB, Karpen SJ, Nathanson MH, Bennett AM: Epidermal growth factor-mediated activation of the ETS domain transcription factor Elk-1 requires nuclear calcium. J Biol Chem. 2002 Jul 26; 2002 Apr 23. PMID: 11971908

Cheng SX, Okuda M, Hall AE, Geibel JP, Hebert SC: Expression of calcium-sensing receptor in rat colonic epithelium: evidence for modulation of fluid secretion. Am J Physiol Gastrointest Liver Physiol. 2002 Jul. PMID: 12065312

Tian S, Liu W, Wu Y, Rafi H, Segal AS, Desir GV: Regulation of the voltage-gated K+ channel KCNA10 by KCNA4B, a novel beta-subunit. Am J Physiol Renal Physiol. 2002 Jul. PMID: 12060596

Wysolmerski JJ, Dann PR, Zelazny E, Dunbar ME, Insogna KL, Guise TA, Perkins AS: Overexpression of parathyroid hormone-related protein causes hypercalcemia but not bone metastases in a murine model of mammary tumorigenesis. J Bone Miner Res. 2002 Jul. PMID: 12096830

Wysolmerski JJ: The evolutionary origins of maternal calcium and bone metabolism during lactation. J Mammary Gland Biol Neoplasia. 2002 Jul. PMID: 12751891

O'Neill AF, Hagar RE, Zipfel WR, Nathanson MH, Ehrlich BE: Regulation of the type III InsP(3) receptor by InsP(3) and calcium. Biochem Biophys Res Commun. 2002 Jun 14. PMID: 12056830

Masiukiewicz US, Mitnick M, Gulanski BI, Insogna KL: Evidence that the IL-6/IL-6 soluble receptor cytokine system plays a role in the increased skeletal sensitivity to PTH in estrogen-deficient women. J Clin Endocrinol Metab. 2002 Jun. PMID: 12050269

Xu X, Tsvetkov LM, Stern DF: Chk2 activation and phosphorylation-dependent oligomerization. Mol Cell Biol. 2002 Jun. PMID: 12024051

Kontaridis MI, Liu X, Zhang L, Bennett AM: Role of SHP-2 in fibroblast growth factor receptor-mediated suppression of myogenesis in C2C12 myoblasts. Mol Cell Biol. 2002 Jun. PMID: 11997521

Boyden LM, Mao J, Belsky J, Mitzner L, Farhi A, Mitnick MA, Wu D, Insogna K, Lifton RP: High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med. 2002 May 16. PMID: 12015390

Wong A, Lamothe B, Lee A, Schlessinger J, Lax I: FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl. Proc Natl Acad Sci U S A. 2002 May 14; 2002 May 7. PMID: 11997436

Schwartz MF, Duong JK, Sun Z, Morrow JS, Pradhan D, Stern DF: Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint. Mol Cell. 2002 May. PMID: 12049741

Egan ME, Glöckner-Pagel J, Ambrose C, Cahill PA, Pappoe L, Balamuth N, Cho E, Canny S, Wagner CA, Geibel J, Caplan MJ: Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells. Nat Med. 2002 May. PMID: 11984593

Hirata K, Pusl T, O'Neill AF, Dranoff JA, Nathanson MH: The type II inositol 1,4,5-trisphosphate receptor can trigger Ca2+ waves in rat hepatocytes. Gastroenterology. 2002 Apr. PMID: 11910359

Sangan P, Rajendran VM, Geibel JP, Binder HJ: Cloning and expression of a chloride-dependent Na+-H+ exchanger. J Biol Chem. 2002 Mar 22; 2001 Dec 28. PMID: 11773056

Geibel JP: Microscopy as a tool for renal research. J Nephrol. 2002 Mar-Apr. PMID: 12027215

Wagner CA, Geibel JP: Acid-base transport in the collecting duct. J Nephrol. 2002 Mar-Apr. PMID: 12027210

Hochstrasser M: New structural clues to substrate specificity in the "ubiquitin system". Mol Cell. 2002 Mar. PMID: 11931752

Schlessinger J: A solid base for assaying protein kinase activity. Nat Biotechnol. 2002 Mar. PMID: 11875418

Khan AJ, King BL, Smith BD, Smith GL, DiGiovanna MP, Carter D, Haffty BG: Characterization of the HER-2/neu oncogene by immunohistochemical and fluorescence in situ hybridization analysis in oral and oropharyngeal squamous cell carcinoma. Clin Cancer Res. 2002 Feb. PMID: 11839675

Chung GG, Kielhorn EP, Rimm DL: Subjective differences in outcome are seen as a function of the immunohistochemical method used on a colorectal cancer tissue microarray. Clin Colorectal Cancer. 2002 Feb. PMID: 12450422

DiGiovanna MP, Roussel RR, Stern DF: Production of antibodies that recognize specific tyrosine-phosphorylated peptides. Curr Protoc Cell Biol. 2002 Feb. PMID: 18228399

Sharp JD, Hausladen DA, Maher MG, Wheeler MA, Altieri DC, Weiss RM: Bladder cancer detection with urinary survivin, an inhibitor of apoptosis. Front Biosci. 2002 Feb 1; 2002 Feb 1. PMID: 11815300

Cruz DN, Brickel HM, Wysolmerski JJ, Gundberg CG, Simpson CA, Kliger AS, Lorber MI, Basadonna GP, Friedman AL, Insogna KL, Bia MJ: Treatment of osteoporosis and osteopenia in long-term renal transplant patients with alendronate. Am J Transplant. 2002 Jan. PMID: 12095058

Kielhorn E, Schofield K, Rimm DL: Use of magnetic enrichment for detection of carcinoma cells in fluid specimens. Cancer. 2002 Jan 1. PMID: 11815978

Laney JD, Hochstrasser M: Assaying protein ubiquitination in Saccharomyces cerevisiae. Methods Enzymol. 2002. PMID: 12073348

Cheung KH, White K, Hager J, Gerstein M, Reinke V, Nelson K, Masiar P, Srivastava R, Li Y, Li J, Zhao H, Li J, Allison DB, Snyder M, Miller P, Williams K: YMD: a microarray database for large-scale gene expression analysis. Proc AMIA Symp. 2002. PMID: 12463803