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Cancer Microbiology (CM)

The Cancer Microbiology (CM) Research Program explores associations between microbial infections and human cancer and accelerates clinical applications of basic science findings. CM has been at the forefront in defining a shift in cancers from classic AIDS-defining cancers to non–AIDS-defining cancers in aging patients on long-term antiretroviral therapy (ART). The goal of the Program is to promote research to discover and clarify the underlying causal relationships between microbial infections and human cancer. Towards this end, CM provides an interdisciplinary and collaborative program structure to accelerate new insights and increase efficacy for therapeutic and preventive cancer interventions.

The main research and translational activities of CM include human tumor viruses, viral immunology and vaccines, associations between bacterial infections and cancer, and the connection between HIV/AIDS and cancer. The program leaders are Dr. Walther Mothes and Dr. Amy Justice.

The goals of the Cancer Microbiology Research Program are to:

  1. Elucidate molecular mechanisms of tumorigenesis by viruses and other infectious agents
  2. Provide the scientific basis for novel treatment and prevention approaches against virus- and other infection-associated cancers