Natalia Issaeva, PhD

Assistant Professor of Surgery (Otolaryngology); Assistant Professor, Division of Otolaryngology, Surgery Department

Research Interests

DNA Repair; DNA Replication; Head and Neck Neoplasms; Oncogenes; Otolaryngology; Genes, Tumor Suppressor; Tumor Suppressor Protein p53; Human papillomavirus 11

Research Organizations

Surgery: Otolaryngology Surgery

Virology Laboratories

Virus and Other Infection-associated Cancers

Research Summary

Our long term research interest is to improve cancer treatment by targeting specific cancer defects.

Currently we are working on:

1. Association between human papilloma virus and the development of head and neck cancer.

2. Link between human papilloma virus and DNA damage signaling and repair in head and neck cancer.

3. Cellular and small molecules modulators of p53 expression and functions;

4. Designing of novel therapeutic strategies to target specific tumors exploiting their various defects.

Specialized Terms: Oncogenes and tumor suppressors; DNA replication and repair; P53 regulation and signaling; Head and neck cancer; Human papilloma virus

Selected Publications

Full List of PubMed Publications

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Contact Info

Natalia Issaeva, PhD
Mailing Address
Otolaryngology SurgeryPO Box 208062
New Haven, CT 06520-8062