Please submit the following electronically through OnCore’s Electronic Protocol Review and Monitoring System (ePRMS) Console. Forms can be found on the forms page. If you have questions or concerns regarding access to this console, please contact ycc.ycci.committees@yale.edu
Please reference the PRC Review Requirements by Protocol Type to determine the protocol type and level of review required.

Therapeutic and Interventional Studies 
Require Full Committee Review unless otherwise determined 
  • Final protocol (not the HIC application)
  • Investigator’s Brochure (as applicable)
  • A copy of the DART Protocol Review Form with the required signatures of the PI and Disease Aligned Research Team (DART) Leader
Non Interventional Non-Therapeutic studies and Observational Studies 
Require administrative review conducted by the Office of Quality Assurance and Training unless otherwise determined
  • Final protocol (If the HIC Application serves as the protocol, this is also acceptable)
  • A copy of the DART Protocol Review Form with the required signatures of the PI and Disease Aligned Research Team (DART) Leader 

Ancillary and Correlative Studies
  • Final protocol (IF the HIC Application serves as the protocol, this is also acceptable)
  • A copy of the DART Protocol Review Form with the required signatures of the PI and Disease Aligned Research Team (DART) Leader  

Multicenter Trials and National Clinical Trials Network Studies
Require review by PRC chair or vice-chair unless otherwise determined