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Translational Research Office

About the Office

The Yale Cancer Center Translational Research Office (TRO) is dedicated to building bridges between clinical and basic researchers to accelerate scientific translation. The TRO provides a bidirectional interface from the bench to the bedside and from bedside-to-bench. Our program facilitates mentoring, consultation, workshops, seminars, pilot funding mechanisms, and annual retreats to catalyze and support new projects.

All YCC members have access to TRO services and YCC Shared Resources. YCC members are encouraged to consult with the TRO in developing and launching new translational research.

Leadership

  • Anthony N. Brady Professor of Medicine (Medical Oncology); Chief Translational Research Officer, Yale Cancer Center; Chief, Head and Neck Cancers/Sarcoma; Co-Leader, Developmental Therapeutics, Yale Cancer Center; Associate Cancer Center Director for Translational Research, Yale Cancer Center

Cancer Survivor Stories

The articles in the Cancer Survivor Stories section feature cancer survivors who have chosen to share their cancer journey—from diagnosis to treatment and beyond—as well as their experience with Smilow Cancer Hospital and Yale Cancer Center’s multidisciplinary team of specialists.

Translational Accomplishments

YCC Translational Research Conclave Awards

2022: Rachel Perry, PhD

2021: Faye Rogers, PhD

2023 Blavatnik Awards

Anton Bennett, PhD: Allagium Therapeutics - Driving change to better health

Michael Girardi MD, FAAD and Jingjing Ren MD: Immunotherapeutics to Treat T Cell Leukemias and Lymphoma

Peter Glazer MD, PhD: Enabling the next generation of safe gene editing therapeutics

Yingqun Huang MD, PhD *: Treating cancer-associated cachexia using a first-in-class molecule

David Spiegel MD, PhD: Transmembrane Anchoring Bifunctional Molecules for Immunotherapy

Thuy Tran MD, PhD*: Bispecific MIF - D-DT Targeting to Enhance Immunotherapy Responses

*Accelerator Awardees

Stephen A. Sherwin’70 MD Translational Research Fellowship 2024

Kim RM Blenman PhD: Protection From Treatment Emergent Thyroid Disease

Thuy Tran MD, PhD: Targeting Macrophage Migration Inhibitory Factor and D-dopachrome Tautomerase to Overcome Immune Resistance in Cancer.

Translational Research Office Resources

YCC Translational Incubator

The Translational Incubator Steering Committee evaluates novel YCC scientific findings for translational potential. Concepts which are appropriate for translation will be evaluated for scientific rigor, alignment with YCC strategic goals and the needs of our community and catchment area, and prioritized for further support from the TRO. This will include workshopping with the Drug Candidate Review Group, grant writing support, facilitation of interaction with Shared Resources, and assistance with grant submission.

  • Professor of Pharmacology and of Molecular Biophysics and Biochemistry; Co-Leader, Developmental Therapeutics, Yale Cancer Center; Co-Director Therapeutics/Chemotherapy Program

  • Anthony N. Brady Professor of Medicine (Medical Oncology); Chief Translational Research Officer, Yale Cancer Center; Chief, Head and Neck Cancers/Sarcoma; Co-Leader, Developmental Therapeutics, Yale Cancer Center; Associate Cancer Center Director for Translational Research, Yale Cancer Center

  • Associate Dean of Research and Susan Dwight Bliss Professor of Epidemiology (Chronic Diseases); Deputy Director (Public Health), Yale Center for Clinical Investigation; Deputy Director, Yale Cancer Center

  • Associate Professor of Cell Biology and of Molecular, Cellular and Development Biology; Co-Leader, Radiobiology and Genome Integrity, Yale Cancer Center; Associate Cancer Center Director, Basic Science

  • Professor of Internal Medicine (Medical Oncology); Director, Clinical Trials Office; Chief Clinical Research Officer, Yale Cancer Center; Associate Director, Clinical Sciences, Yale Cancer Center

  • Amy and Joseph Perella Professor of Medicine (Medical Oncology); Chief, Experimental Therapeutics; Associate Cancer Center Director, Experimental Therapeutics

  • Associate Dean for Health Equity Research and C.N.H. Long Professor of Internal Medicine (General Medicine), of Epidemiology (Chronic Disease) and of Public Health (Social And Behavioral Sciences) & Professor of Internal Medicine (General Medicine); Affiliated Faculty, Yale Institute for Global Health; Founding Director, Equity Research and Innovation Center (ERIC), Yale School of Medicine; Director, Center for Research Engagement (CRE); Director, Center for Community Engagement and Health Equity; Deputy Director for Health Equity Research and Workforce Development, Yale Center for Clinical Investigation (YCCI); Director, Pozen-Commonwealth Fund Fellowship in Health Equity Leadership