Chaos, hope, and the lupus butterfly theory
Yale researchers believe some antibodies associated with lupus may be sources of both chaos and hope in cancer. Borrowing from the Greek legend of Pandora’s box and chaos theory by calling it the “lupus butterfly theory,” the idea was described recently in the journal Nature Reviews Rheumatology.
Sang Taek Kim Returns to YSM to Lead Immunotherapy Adverse Events Program
A physician scientist, Sang Taek Kim, MD, PhD, assistant professor of medicine (rheumatology), is interested in the autoimmune complications induced by cancer immunotherapy. In his new role, he serves as director of the Immunotherapy Adverse Events in Rheumatology Program.
New Outpatient Raynaud Treatment Saves Fingers and Toes
In a new outpatient treatment at Yale, epopostrenol infusions are safely given to patients whose fingers and toes are damaged by severe Raynaud phenomenon, also known as Raynaud’s phenomenon, to prevent amputation. Previously, these patients were sent to the emergency department, where they often waited for days before receiving treatment.
New Cell Therapy Program to Offer Advanced Cell-based Treatment for Patients With Severe Lupus
A new technology called chimeric antigen receptor (CAR) T-cell therapy has been successfully used to treat patients with cancer. Fotios Koumpouras, MD, Nathan Johnson, MD, PhD, and Marwin Groener, MD, are working to apply this novel branch of science to help patients with lupus.
Philanthropist Nancy Davis Opens Up About Life with Multiple Sclerosis and Her Mission to Help Others
Philanthropist Nancy Davis tells her story of living with multiple sclerosis, from her diagnosis after a ski accident to how she eventually found the treatment plan that was right for her. Yale Neurology Chair David Hafler, MD also speaks about how far research into the autoimmune disease has come and what the most effective treatment strategies are.Source: People
Large Gift Establishes Colton Center for Autoimmunity at Yale School of Medicine
Philanthropists Judith and Stewart Colton have donated a major gift to establish the Colton Center for Autoimmunity at Yale, under the direction of Joseph E. Craft, MD, Paul B. Beeson Professor of Medicine and professor of immunobiology.
Better Science, Better Lives: Women's Health Research at Yale is Working for You
Across the country, it’s becoming clearer every day: We must study the health of women. We must study the influence of sex-and-gender differences on health. And it’s time for all aspects of medical research and practice to embrace this change.
Heather Martin Education Fund in Rheumatology
One of the first steps toward achieving groundbreaking diagnostic and treatment solutions is to arm future leaders in lupus with in-depth knowledge and a greater understanding of the disease. To this end, Kellie Martin and her husband Keith Christian have generously partnered with Yale School of Medicine (YSM) to create the Heather Martin Education Fund in Rheumatology in memory of Kellie’s sister, Heather. The fund will bolster lupus expertise, moving us closer to delivering novel solutions.
The enemy within: Gut bacteria drive autoimmune disease
Bacteria found in the small intestines of mice and humans can travel to other organs and trigger an autoimmune response, according to a new Yale study. The researchers also found that the autoimmune reaction can be suppressed with an antibiotic or vaccine designed to target the bacteria, they said.
From the Gut: How Beneficial Bacteria Inside Our Bodies Might Trigger and Treat Autoimmune Disease
Two years after obtaining a Women’s Health Research at Yale seed grant, Dr. Martin Kriegel has continued exploring how beneficial bacteria that live in the gut might trick the body into an autoimmune reaction known as antiphospholipid syndrome.