Using Particles That Are Smaller Than the Head of a Pin to Treat Cancer
Thanks in part to research begun more than a decade ago with funding from Women’s Health Research at Yale, Dr. W. Mark Saltzman is working with colleagues on a way to deploy effective cancer-fighting medication safely with the help of nanoparticles.
Yale advances in a ‘March Madness’-styled scientific research competition
Two Yale research teams recently moved forward into round four of a different kind of March Madness competition. The event, called STAT Madness, aims to raise awareness about scientific breakthroughs from national institutions and is sponsored by the Boston-based news organization STAT. The ongoing heated competition consists of voting for the best innovation in science from the past year. The current round of voting ends at midnight on Thursday, March 22.Source: Yale News
Engineering and Medicine Combine to Fight Brain Cancer
A collaboration between two laboratories – one in Engineering and the other in Medicine – has led to a promising drug delivery system that uses nanoparticles to fight a particularly aggressive and hard-to-treat brain cancer.Source: Yale School of Engineering & Applied Science
‘Sticky’ particles promise more precise drug delivery for brain cancer
A Yale research team has found that by tinkering with the surface properties of drug-loaded nanoparticles, they can potentially direct these particles to specific cells in the brain. By making nanoparticles bioadhesive, or “sticky,” the researchers have answered a long-standing question: Once you get the particles to the brain, how do you get them to interact with the cancer cells there? Their findings are published May 19 in Nature Communications.
Study points to potential new brain cancer treatment
A recent Yale study may have found a new way to fight brain cancer. Researchers at the Yale School of Medicine’s Department of Therapeutic Radiology have identified a genetic defect in brain tumor cells that makes them sensitive to a class of drugs known as PARP inhibitors. The defect, a mutation of the IDH1 and IDH2 genes, impairs cancer cells’ ability to repair DNA, making them especially vulnerable. The study was published on Feb. 1 in the journal Science Translational Medicine.Source: Yale Daily News
‘Explosive growth’ of interventional oncology prompts formation of new society
The board of directors for World Conference on Interventional Oncology, a nonprofit association that supports and promotes the field, has established a society to further its mission. The Society of Interventional Oncology will be the only membership-based organization dedicated entirely to interventional oncology, a subspecialty field of interventional radiology. Jeff Geschwind Interventional oncology focuses on the treatment of cancer through minimally invasive procedures performed under image guidance, such as X-ray, MRI, PET scan, CT scan or ultrasound.Source: HemOnc Today
CaSB@Yale launches with $9.5M federal grant to battle deadliest cancers
Yale University researchers across a spectrum of disciplines are coming together to fight some of the deadliest forms of cancer with a novel approach that has gained support from the National Cancer Institute (NCI) of the National Institutes of Health (NIH).
From Nanotechnology, A Better Prognostic Tool For Brain Cancer
A new nano-fabricated platform for observing brain cancer cells provides a much more detailed look at how the cells migrate and a more accurate post-surgery prognosis for brain cancer (glioblastoma) patients.Source: Yale School of Engineering and Applied Science
Next head of Jonathan Edwards College to be W. Mark Saltzman
President Peter Salovey announced W. Mark Saltzman, the Goizueta Foundation Professor of Chemical and Biomedical Engineering, as the next head of Jonathan Edwards College (JE) on May 5 to students in the JE dining hall.Source: Yale News