Treatment with Genetically Altered Viruses Targets and Destroys Ovarian Cancer in Mice
Researchers have successfully eliminated chemotherapy-resistant ovarian cancer cells in mice using a single injection of two viruses genetically combined and altered to be safe, leading to long-term survival and demonstrating a potential breakthrough treatment for women.
Once-Common Hysterectomy Technique Linked to Worse Uterine Cancer Outcomes
Every year, nearly 700,000 American women have surgery to remove their uterus (hysterectomy) or uterine fibroids (myomectomy). A laparoscopic surgical technique once commonly used in these procedures could be worsening the outcomes for women who have undiagnosed uterine cancer at the time of the procedure, Yale Cancer Center scientists report in the Journal of Clinical Oncology.
Statement concerning recall of Allergan breast implants following cancer link
At the request of the U.S. Food and Drug Administration, textured breast implants made by Allergan are being recalled. The implants have been linked to a rare cancer called Anaplastic Large Cell Lymphoma. Dr. Tomer Avraham comments.
8 Ways to Be There for Yourself After a Breast Cancer Diagnosis
Although learning to cope after a breast cancer diagnosis is a really individual process, experts and survivors we spoke with emphasized that there are a few ways you might be able to make the experience even a little bit easier. Here are their suggestions.Source: Self Magazine
Yale Cancer Center and Smilow Cancer Hospital physicians recognized as CT Magazine 'Best Doctors'
Connecticut Magazine has named 72 Yale Cancer Center and Smilow Cancer Hospital physicians to its 2019 Best Doctors guide. Published in the magazine’s June issue, the Best Doctors list consists of 782 Connecticut physicians from 78 medical specialties.
Breast cancer care in U.S. territories lags behind care in states
Older women residing in the U.S territories are less likely to receive recommended or timely care for breast cancer compared with similar women residing in the continental United States, according to Yale researchers. Their findings were published in the March issue of Health Affairs.
Breast cancer breakthrough may have been found in Connecticut
A big breakthrough in the battle against breast cancer may have been found in Connecticut. The discovery was make by a local researcher and helped by a grant from the Terri Brodeur Breast Cancer Foundation with money raised by the Southern Connecticut Breast Cancer Walk. It starts with hundreds of walkers every fall and ends in a lab. The local fight against breast cancer is spearheaded by the foundation. "I feel like a lot of us clinicians have insight into what's going on with the disease type but it's very hard to compete with people who are doing research full time," said Dr. Erin Hofstatter, Yale Cancer Center. "Terri Brodeur has been valuable in giving me a chance."Source: WFSB
Yale’s advance in breast cancer surgery to be tested in nationwide study
Removing a small amount of extra tissue around a breast cancer tumor may keep a patient from having a recurrence of the cancer or of having to return to the operating table because not all of the malignant cells were removed in the first operation. That’s the theory that’s being tested in a nationwide clinical trial sponsored by the Yale Cancer Center called SHAVE2. Dr. Anees Chagpar, assistant director of global oncology at the Yale School of Medicine and former director of the Breast Center, is the principal investigator. Chagpar oversaw the first SHAVE trial at Yale, which involved 235 patients with stage 0 to stage 3 breast cancer who were given a partial mastectomy, also known as a lumpectomy. Some were given normal lumpectomies, while others had more tissue removed from around the tumor site, known as cavity shave margins.Source: New Haven Register
Opportunities to vaccinate young women against HPV missed at alarming rate
en aged 18-26 who were eligible to receive Human Papilloma Virus (HPV) vaccine have missed at least one opportunity to receive the vaccine during a visit to an obstetrics and gynecology clinic, Yale researchers report. This study also confirms previous research showing racial disparities in vaccination for HPV: Women who identify as black are 61% more likely have had a missed opportunity than women who identify as white. These findings are published in the American Journal of Obstetrics and Gynecology. HPV is a well-known cause of pre-cancerous cervical lesions, which, if untreated, could develop into cervical cancer. Immunization against HPV has been shown to be safe and effective in preventing these pre-cancerous lesions. The two-dose HPV vaccine is recommended for administration to It is recommended that girls ages 11-12 receive the two-dose HPV vaccine, and that those through age 26 receive the three-dose vaccination for “catch-up.”
Can Digestive Chemistry Uncover Sex-Specific Causes of Colon Cancer?
Dr. Caroline Helen Johnson received this year’s Wendy U. and Thomas C. Naratil Pioneer Award and co-funding from the Yale Cancer Center to explore hormones and environmental factors related to metabolite production (such as sugars and amino acids) and beneficial bacteria that live in the colon as possible sources of gender difference.
Mystery of breast cancer risk gene solved, 20 years after its discovery
More than 20 years after scientists revealed that mutations in the BRCA1 gene predispose women to breast cancer, Yale scientists have pinpointed the molecular mechanism that allows those mutations to wreak their havoc. The findings, reported Oct. 4 in the journal Nature, will not only help researchers design drugs to combat breast and ovarian cancers, but also help identify women who are at high risk of developing them, the authors say. “There have been about 14,000 papers written about BRCA1, and you would think we already know everything about the gene, but we don’t,” said senior author Patrick Sung, professor of molecular biophysics and biochemistry and of therapeutic radiology and member of the Yale Cancer Center.