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TSH Levels Linked to Papillary Thyroid Cancer, With Sex Differences
Thyroid-stimulating hormone (TSH) levels show a significant association with the risk of papillary thyroid cancer (PTC) that appears gender-based, with lower-than-normal serum TSH levels years before a cancer diagnosis linked to an increased risk of PTC in women, while in contrast a higher-than-normal prediagnostic level is linked to a greater risk in men.
Furthermore, increased TSH levels falling even within the normal TSH range show a trend of being associated with a decreased risk of PTC in both genders.
"The findings by gender are novel," first author Yawei Zhang, MD, PhD, of the Yale School of Public Health and the Yale Cancer Center, in New Haven, Connecticut, told Medscape Medical News.
Source: Medscape