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Breast, Phase II

Study to Assess Clinical Activity of Zelenectide Pevedotin in Participants With Advanced Breast Cancer

What is the purpose of this trial?

This is a global, multicenter, open-label study that aims to assess the efficacy and safety of zelenectide pevedotin in participants with NECTIN4-amplified recurrent, unresectable, or metastatic breast cancer who have received prior therapy (see inclusion criteria below). The study will comprise of 2 cohorts. Cohort A will include participants with hormone receptor positive/ human epidermal growth factor receptor 2 negative [HR+/HER2-] breast cancer, whereas Cohort B will include participants with triple-negative breast cancer (TNBC).

Contact Information

For more information about this study, including how to volunteer, contact Carl Brown

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  • Last Updated
    11/05/2025
  • Study HIC
    #2000039480