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Daniel DiMaio, MD, PhD

Waldemar Von Zedtwitz Professor of Genetics and Professor of Molecular Biophysics and Biochemistry and of Therapeutic Radiology; Deputy Director, Yale Cancer Center

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Daniel DiMaio, MD, PhD



The DiMaio laboratory is studying the molecular mechanisms of how human papillomaviruses enter cells, with a particular focus on identifying the cellular proteins that mediate virus entry and intracellular trafficking and determining their molecular mechanisms of action. In addition, it is using viral transmembrane proteins as a basis to develop a class of artificial small transmembrane proteins with a variety of biological activities, including the ability to form tumors and confer resistance to virus infection. Some of these proteins are the simplest proteins ever described and their study will reveal new features of protein action and the basis for specificity in protein-protein interactions.

Education & Training

  • Postdoctoral Fellow
    Harvard University (1983)
  • PhD
    Johns Hopkins University (1981)
  • MD
    Johns Hopkins University (1978)
  • BS
    Yale University, Biology (1974)

Honors & Recognition

AwardAwarding OrganizationDate
Lifetime Achievement AwardYale Cancer Center2023
Outstanding Investigator AwardNational Cancer Institute2020
Member, Connecticut Academy of Science and Engineering2014
Honorary ProfessorUniversity College London2012
Fellow, American Association for the Advancement of Science2003
Graduate Mentoring Award in the Natural SciencesYale University Graduate School of Arts and Sciences2001
Fellow, American Academy of Microbiology2000
Member, American Society for Clinical Investigation1993
MERIT AwardNational Institutes of Health1992
Mallinckrodt Scholar Award1983

Professional Service

Yale UniversityDirector, Division of Biological Sciences2014 - 2018
Board of Scientific Advisors, National Cancer InstituteMember2012 - 2017
American Society for MicrobiologyChairman, Division S (DNA viruses)1998 - 1999

Departments & Organizations