Recent publications by Yale Cancer Center members.
Estimating Breast Cancer Overdiagnosis After Screening Mammography Among Older Women in the United States. Richman IB, Gross CP. Ann Intern Med. 2024 Mar;177(3):403-404.
De novo-designed transmembrane proteins bind and regulate a cytokine receptor. Mravic M, He L, Kratochvil HT, Hu H, Nick SE, Bai W, Edwards A, Jo H, Wu Y, DiMaio D, DeGrado WF. Nat Chem Biol. 2024 Mar 13. doi: 10.1038/s41589-024-01562-z. Epub ahead of print.
Improving lifestyle behaviors during chemotherapy for breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial. Puklin LS, Ferrucci LM, Harrigan M, McGowan C, Zupa M, Cartmel B, Li FY, Ligibel JA, Spiegelman D, Sharifi M, Sanft T, Irwin ML. Cancer. 2024 Mar 12. doi: 10.1002/cncr.35280. Epub ahead of print.
Impact of 18F-FDG PET Intensity Normalization on Radiomic Features of Oropharyngeal Squamous Cell Carcinomas and Machine Learning-Generated Biomarkers. Haider SP, Zeevi T, Sharaf K, Gross M, Mahajan A, Kann BH, Judson BL, Prasad ML, Burtness B, Aboian M, Canis M, Reichel CA, Baumeister P, Payabvash S. J Nucl Med. 2024 Mar 21:jnumed.123.266637. Online ahead of print.
Oncology hospitalist impact on hospice utilization. Prsic E, Morris JC, Adelson KB, Parker NA, Gombos EA, Kottarathara MJ, Novosel M, Castillo L, Gould Rothberg BE. Cancer. 2023 Dec 1;129(23):3797-3804.
A Comparison Between In-Person and Virtual Communication Skills OSCE for Medical Students. Choi A, Murtha TD, Morrison LJ, Talwalkar JS. J Med Educ Curric Dev. 2024 Mar 25;11:23821205241241375.
The Right Dose: Results of a Patient Advocate-Led Survey of Individuals With Metastatic Breast Cancer Regarding Treatment-Related Side Effects and Views About Dosage Assessment to Optimize Quality of Life. Loeser A, Kim JS, Peppercorn J, Burkard ME, Niemierko A, Juric D, Kalinsky K, Rugo H, Glenn L, Hodgdon C, Maues J, Johnson S, Padron N, Parekh K, Lustberg M, Bardia A. JCO Oncol Pract. 2024 Mar 22:OP2300539. Epub ahead of print.
An algorithm for standardization of tumor Infiltrating lymphocyte evaluation in head and neck cancers. Xirou V, Moutafi M, Bai Y, Nwe Aung T, Burela S, Liu M, Kimple RJ, Shabbir Ahmed F, Schultz B, Flieder D, Connolly DC, Psyrri A, Burtness B, Rimm DL. Oral Oncol. 2024 Mar 27;152:106750.
Impact of the Breast Cancer Index for Extended Endocrine Decision-Making: First Results of the Prospective BCI Registry Study. Sanft TB, Wong J, O'Neal B, Siuliukina N, Jankowitz RC, Pegram MD, Fox JR, Zhang Y, Treuner K, O'Shaughnessy JA. J Natl Compr Canc Netw. 2024 Mar 4;22(2):99-107.
Renovating the Commission on Cancer's Quality Measure Portfolio. Boffa DJ, Lum SS, Palis B, McCabe R, Park KU, Siddiqui MM, Facktor M, Mullet T, Nelson H. Ann Surg. 2024 Mar 28. Online ahead of print.
EGFR targeting PhosTACs as a dual inhibitory approach reveals differential downstream signaling. Hu Z, Chen PH, Li W, Krone M, Zheng S, Saarbach J, Velasco IU, Hines J, Liu Y, Crews CM. Sci Adv. 2024 Mar 29;10(13):eadj7251.
How Far We've Come. Sznol M, Weber JS. Cancer J. 2024 Mar-Apr 01;30(2):47.
Digital spatial proteomic profiling reveals immune checkpoints as biomarkers in lymphoid aggregates and tumor microenvironment of desmoplastic melanoma. Su DG, Schoenfeld DA, Ibrahim W, Cabrejo R, Djureinovic D, Baumann R, Rimm DL, Khan SA, Halaban R, Kluger HM, Olino K, Galan A, Clune J. J Immunother Cancer. 2024 Mar 21;12(3):e008646.
Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape. Boddu PC, Gupta AK, Roy R, De La Peña Avalos B, Olazabal-Herrero A, Neuenkirchen N, Zimmer JT, Chandhok NS, King D, Nannya Y, Ogawa S, Lin H, Simon MD, Dray E, Kupfer GM, Verma A, Neugebauer KM, Pillai MM. Mol Cell. 2024 Mar 22:S1097-2765(24)00175-8. Online ahead of print
Variations in the genomic profiles and clinical behavior of meningioma by racial and ethnic group. Tabor JK, Dincer A, O'Brien J, Lei H, Vetsa S, Vasandani S, Jalal MI, Yalcin K, Morales-Valero SF, Marianayagam N, Alanya H, Elsamadicy AA, Millares Chavez MA, Aguilera SM, Mishra-Gorur K, McGuone D, Fulbright RK, Jin L, Erson-Omay EZ, Günel M, Moliterno J. J Neurosurg. 2024 Mar 22:1-9.
Clinical Outcomes Among Immunotherapy-Treated Patients With Primary Cardiac Soft Tissue Sarcomas: A Multicenter Retrospective Study. Nassar AH, El-Am E, Denu R, Abou Alaiwi S, El Zarif T, Macaron W, Abdel-Wahab N, Desai A, Smith C, Parikh K, Abbasi M, Bou Farhat E, Williams JM, Collins JD, Al-Hader A, McKay RR, Malvar C, Sabra M, Zhong C, El Alam R, Chehab O, Lima J, Phan M, Dalla Pria HF, Trevino A, Neilan TG, Kwan JM, Ravi V, Deshpande H, Demetri G, Choueiri TK, Naqash AR. JACC CardioOncol. 2024 Jan 16;6(1):71-79.
Clinical activity, pharmacokinetics, and pharmacodynamics of oral hypomethylating agents for myelodysplastic syndromes/neoplasms and acute myeloid leukemia: A multidisciplinary review. Haumschild R, Kennerly-Shah J, Barbarotta L, Zeidan AM. J Oncol Pharm Pract. 2024 Mar 21:10781552241238979.
Updated Analysis of Comparative Toxicity of Proton and Photon Radiation for Prostate Cancer. Yu JB, DeStephano DM, Jeffers B, Horowitz DP, Soulos PR, Gross CP, Cheng SK. J Clin Oncol. 2024 Mar 20:JCO2301604.