Cancer Immunology Recent Publications
2024
- Chart review study of real-world clinical outcomes in patients with cutaneous T-cell lymphoma treated with extracorporeal photopheresis in the US in 2017-2019.Girardi M, Carlson K, Huang X, Corman SL, Edmundson P, Schmier J, Kale HP, Raina R, Foss F. J Dermatolog Treat. 2024 Dec; 2024 Jun 9. PMID: 38852942.
- Nuclear-penetrating scleroderma autoantibody inhibits topoisomerase 1 cleavage complex formation.May CK, Noble PW, Herzog EL, Meffre E, Hansen JE. Biochem Biophys Res Commun. 2024 Aug 6; 2024 May 14. PMID: 38759301.
- Maturation of germinal center B cells after influenza virus vaccination in humans.McIntire KM, Meng H, Lin TH, Kim W, Moore NE, Han J, McMahon M, Wang M, Malladi SK, Mohammed BM, Zhou JQ, Schmitz AJ, Hoehn KB, Carreño JM, Yellin T, Suessen T, Middleton WD, Teefey SA, Presti RM, Krammer F, Turner JS, Ward AB, Wilson IA, Kleinstein SH, Ellebedy AH. J Exp Med. 2024 Aug 5; 2024 Jun 27. PMID: 38935072.
- Adenocarcinoma of anogenital mammary gland type arising from encapsulated papillary carcinoma: A rare vulvar tumor mimicking breast carcinoma.Tang H, Laskin WB, Luan Y, McNiff JM, Zhan H. J Cutan Pathol. 2024 Aug; 2024 May 6. PMID: 38711196.
- Cutaneous diatoms from diatomaceous earth mimicking myiasis infection.Roy SF, Micevic G, McNiff JM, Christensen SR, Cowper SE. Pathology. 2024 Aug; 2024 Feb 17. PMID: 38471986.
- The Xenorhabdus nematophila LrhA transcriptional regulator modulates production of γ-keto-N-acyl amides with inhibitory activity against mutualistic host nematode egg hatching.Lam YC, Hamchand R, Mucci NC, Kauffman SJ, Dudkina N, Reagle EV, Casanova-Torres ÁM, DeCuyper J, Chen H, Song D, Thomas MG, Palm NW, Goodrich-Blair H, Crawford JM. Appl Environ Microbiol. 2024 Jul 24; 2024 Jun 25. PMID: 38916293.
- Single-cell analysis reveals transcriptional dynamics in healthy primary parathyroid tissue.Venkat A, Carlino MJ, Lawton BR, Prasad ML, Amodio M, Gibson CE, Zeiss CJ, Youlten SE, Krishnaswamy S, Krause DS. Genome Res. 2024 Jul 23; 2024 Jul 23. PMID: 38977309.
- Biomarker development for PD-(L)1 axis inhibition: a consensus view from the SITC Biomarkers Committee.Monette A, Warren S, Barrett JC, Garnett-Benson C, Schalper KA, Taube JM, Topp B, Snyder A. J Immunother Cancer. 2024 Jul 20; 2024 Jul 20. PMID: 39032943.
- Camptothecin-loaded mesoporous silica nanoparticles functionalized with CpG oligodeoxynucleotide as a new approach for skin cancer treatment.Qureshi M, Viegas C, Duarte SOD, Girardi M, Shehzad A, Fonte P. Int J Pharm. 2024 Jul 20; 2024 Jun 13. PMID: 38878838.
- Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma.Valdez CN, Sánchez-Zuno GA, Osmani L, Ibrahim W, Galan A, Bacchiocchi A, Halaban R, Kulkarni RP, Kang I, Bucala R, Tran T. Oncotarget. 2024 Jul 19; 2024 Jul 19. PMID: 39028303.
- Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation.Zhang P, Gorman J, Tsybovsky Y, Lu M, Liu Q, Gopan V, Singh M, Lin Y, Miao H, Seo Y, Kwon A, Olia AS, Chuang GY, Geng H, Lai YT, Zhou T, Mascola JR, Mothes W, Kwong PD, Lusso P. Cell Rep. 2024 Jul 18; 2024 Jul 18. PMID: 39028623.
- UBXN3B is crucial for B lymphopoiesis.Geng T, Yang D, Lin T, Harrison AG, Wang B, Cao Z, Torrance B, Fan Z, Wang K, Wang Y, Yang L, Haynes L, Cheng G, Vella AT, Flavell RA, Pereira JP, Fikrig E, Wang P. EBioMedicine. 2024 Jul 16; 2024 Jul 16. PMID: 39018756.
- The West Nile virus genome harbors essential riboregulatory elements with conserved and host-specific functional roles.Huston NC, Tsao LH, Brackney DE, Pyle AM. Proc Natl Acad Sci U S A. 2024 Jul 16; 2024 Jul 10. PMID: 38985757.
- A crisis in clinical research.Hong DS, LoRusso P, Sznol M. J Immunother Cancer. 2024 Jul 11; 2024 Jul 11. PMID: 38991727.
- Phase 2 Trial of the Farnesyltransferase Inhibitor Tipifarnib for Relapsed/Refractory Peripheral T Cell Lymphoma.Witzig TE, Sokol L, Kim WS, de la Cruz F, Martin Garcia-Sancho AM, Advani RH, Roncero Vidal JM, De Oña R, Marin-Niebla A, Izquierdo AR, Terol MJ MD, Domingo-Domenech E, Saunders A, Bendris N, Mackey J, Leoni M, Foss FM. Blood Adv. 2024 Jul 11; 2024 Jul 11. PMID: 38991123.
- Western diet reduces small intestinal intraepithelial lymphocytes via FXR-Interferon pathway.Hung CT, Ma C, Panda SK, Trsan T, Hodel M, Frein J, Foster A, Sun S, Wu HT, Kern J, Mishra R, Jain U, Ho YC, Colonna M, Stappenbeck TS, Liu TC. Mucosal Immunol. 2024 Jul 9; 2024 Jul 9. PMID: 38992433.
- Downregulation of adipose LPL by PAR2 contributes to the development of hypertriglyceridemia.Huang Y, Chen L, Li L, Qi Y, Tong H, Wu H, Xu J, Leng L, Cheema S, Sun G, Xia Z, McGuire J, Rodrigues B, Young LH, Bucala R, Qi D. JCI Insight. 2024 Jul 8; 2024 Jul 8. PMID: 38973609.
- Methionine sulfoxide reductase B2 protects against cardiac complications in diabetes mellitus.Lee SH, Cho S, Lee JY, Kim JY, Kim S, Jeong M, Hong JY, Kim GY, Lee SW, Kim E, Kim J, Kim JW, Hwa J, Kim WH. Diabetol Metab Syndr. 2024 Jul 5; 2024 Jul 5. PMID: 38970135.
- PI3Kγ in B cells promotes antibody responses and generation of antibody-secreting cells.Lanahan SM, Yang L, Jones KM, Qi Z, Cabrera EC, Cominsky LY, Ramaswamy A, Barmada A, Gabernet G, Uthaya Kumar DB, Xu L, Shan P, Wymann MP, Kleinstein SH, Rao VK, Mustillo P, Romberg N, Abraham RS, Lucas CL. Nat Immunol. 2024 Jul 3; 2024 Jul 3. PMID: 38961274.
- A unified metric of human immune health.Sparks R, Rachmaninoff N, Lau WW, Hirsch DC, Bansal N, Martins AJ, Chen J, Liu CC, Cheung F, Failla LE, Biancotto A, Fantoni G, Sellers BA, Chawla DG, Howe KN, Mostaghimi D, Farmer R, Kotliarov Y, Calvo KR, Palmer C, Daub J, Foruraghi L, Kreuzburg S, Treat JD, Urban AK, Jones A, Romeo T, Deuitch NT, Moura NS, Weinstein B, Moir S, Ferrucci L, Barron KS, Aksentijevich I, Kleinstein SH, Townsley DM, Young NS, Frischmeyer-Guerrerio PA, Uzel G, Pinto-Patarroyo GP, Cudrici CD, Hoffmann P, Stone DL, Ombrello AK, Freeman AF, Zerbe CS, Kastner DL, Holland SM, Tsang JS. Nat Med. 2024 Jul 3; 2024 Jul 3. PMID: 38961223.
- Quantitative Measurement of HER2 Expression in Non-Small Cell Lung Cancer With a High-Sensitivity Assay.Liu M, Vathiotis I, Robbins CJ, Chan NNN, Moutafi M, Burela S, Xirou V, Schalper KA, Herbst RS, Syrigos K, Rimm DL. Mod Pathol. 2024 Jul 2; 2024 Jul 2. PMID: 38964502.
- Interleukin-7-based identification of liver lymphatic endothelial cells reveals their unique structural features.Yang Y, Jeong J, Su T, Lai S, Zhang P, Garcia-Milian R, Graham M, Liu X, McConnell MJ, Utsumi T, Pereira J, Iwakiri Y. JHEP Rep. 2024 Jul; 2024 Mar 18. PMID: 38966234.
- Novel strategies for targeting neutrophil against myocardial infarction.Jiang K, Hwa J, Xiang Y. Pharmacol Res. 2024 Jul; 2024 Jun 10. PMID: 38866263.
- A small-molecule allele-selective transcriptional inhibitor of the MIF immune susceptibility locus.Li J, Leng L, Pantouris G, Manjula R, Piecychna M, Abriola L, Hu B, Lolis E, Armstrong ME, Donnelly SC, Bucala R. J Biol Chem. 2024 Jul; 2024 Jun 3. PMID: 38838773.
- Single-Cell Transcriptomic Analyses of Brain Parenchyma in Patients With New-Onset Refractory Status Epilepticus (NORSE).Hanin A, Zhang L, Huttner AJ, Plu I, Mathon B, Bielle F, Navarro V, Hirsch LJ, Hafler DA. Neurol Neuroimmunol Neuroinflamm. 2024 Jul; 2024 May 29. PMID: 38810181.
- Tumor Necrosis Factor Receptor-2 Signals Clear-Cell Renal Carcinoma Proliferation via Phosphorylated 4E Binding Protein-1 and Mitochondrial Gene Translation.Al-Lamki RS, Tolkovsky AM, Alawwami M, Lu W, Field SF, Wang J, Pober JS, Bradley JR. Am J Pathol. 2024 Jul; 2024 Mar 25. PMID: 38537932.
- The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases.Sumida TS, Cheru NT, Hafler DA. Nat Rev Immunol. 2024 Jul; 2024 Feb 19. PMID: 38374298.
- Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance.Yu J, Yan Y, Li S, Xu Y, Parolia A, Rizvi S, Wang W, Zhai Y, Xiao R, Li X, Liao P, Zhou J, Okla K, Lin H, Lin X, Grove S, Wei S, Vatan L, Hu J, Szumilo J, Kotarski J, Freeman ZT, Skala S, Wicha M, Cho KR, Chinnaiyan AM, Schon S, Wen F, Kryczek I, Wang S, Chen L, Zou W. Cell. 2024 Jun 28; 2024 Jun 28. PMID: 38968937.
- Percent Final Height Is a Novel Method That Identifies Differences Between the Rate of Development in American Children of Different Races.Taylor TN, Yang AA, Lee TM, Diejomaoh RM, Bridges CS, Kan JH, Smith BG, Cooperman DR. J Pediatr Orthop. 2024 Jun 28; 2024 Jun 28. PMID: 38938106.
- Neutrophils insert elastase into hepatocytes to regulate calcium signaling in alcohol-associated hepatitis.Ogino N, Leite MF, Guerra MT, Kruglov E, Asashima H, Hafler DA, Ito T, Pereira JP, Peiffer BJ, Sun Z, Ehrlich BE, Nathanson MH. J Clin Invest. 2024 Jun 25; 2024 Jun 25. PMID: 38916955.
- A causal link between autoantibodies and neurological symptoms in long COVID.Santos Guedes de Sa K, Silva J, Bayarri-Olmos R, Brinda R, Alec Rath Constable R, Colom Diaz PA, Kwon DI, Rodrigues G, Wenxue L, Baker C, Bhattacharjee B, Wood J, Tabacof L, Liu Y, Putrino D, Horvath TL, Iwasaki A. medRxiv. 2024 Jun 19; 2024 Jun 19. PMID: 38947091.
- A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance.Mertens RT, Misra A, Xiao P, Baek S, Rone JM, Mangani D, Sivanathan KN, Arojojoye AS, Awuah SG, Lee I, Shi GP, Petrova B, Brook JR, Anderson AC, Flavell RA, Kanarek N, Hemberg M, Nowarski R. Immunity. 2024 Jun 19; 2024 Jun 19. PMID: 38906145.
- A dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models.Stabach PR, Sims D, Gomez-Bañuelos E, Zehentmeier S, Dammen-Brower K, Bernhisel A, Kujawski SE, Lopez SG, Petri M, Goldman DW, Lester ER, Le Q, Ishaq T, Kim H, Srivastava S, Kumar D, Pereira JP, Yarema KJ, Koumpouras F, Andrade F, Braddock DT. JCI Insight. 2024 Jun 18; 2024 Jun 18. PMID: 38888971.
- Inflammatory Response and Defects on Myelin Integrity in the Olfactory System of K18hACE2 Mice Infected with SARS-CoV-2.Martin-Lopez E, Brennan B, Mao T, Spence N, Meller SJ, Han K, Yahiaoui N, Wang C, Iwasaki A, Greer CA. eNeuro. 2024 Jun; 2024 Jun 17. PMID: 38834299.
- The single-cell opioid responses in the context of HIV (SCORCH) consortium.Ament SA, Campbell RR, Lobo MK, Receveur JP, Agrawal K, Borjabad A, Byrareddy SN, Chang L, Clarke D, Emani P, Gabuzda D, Gaulton KJ, Giglio M, Giorgi FM, Gok B, Guda C, Hadas E, Herb BR, Hu W, Huttner A, Ishmam MR, Jacobs MM, Kelschenbach J, Kim DW, Lee C, Liu S, Liu X, Madras BK, Mahurkar AA, Mash DC, Mukamel EA, Niu M, O'Connor RM, Pagan CM, Pang APS, Pillai P, Repunte-Canonigo V, Ruzicka WB, Stanley J, Tickle T, Tsai SA, Wang A, Wills L, Wilson AM, Wright SN, Xu S, Yang J, Zand M, Zhang L, Zhang J, Akbarian S, Buch S, Cheng CS, Corley MJ, Fox HS, Gerstein M, Gummuluru S, Heiman M, Ho YC, Kellis M, Kenny PJ, Kluger Y, Milner TA, Moore DJ, Morgello S, Ndhlovu LC, Rana TM, Sanna PP, Satterlee JS, Sestan N, Spector SA, Spudich S, Tilgner HU, Volsky DJ, White OR, Williams DW, Zeng H. Mol Psychiatry. 2024 Jun 15; 2024 Jun 15. PMID: 38879719.
- Systemic Treatment with siRNA Targeting Gamma-Secretase Activating Protein Inhibits Amyloid-β Accumulation in Alzheimer's Disease.Kim S, Ullah I, Beloor J, Chung K, Kim J, Yi Y, Kang E, Yun G, Heo S, Pyun SH, Kim SH, Kumar P, Lee SK. Biomater Res. 2024; 2024 Jun 12. PMID: 38868092.
- An atlas of human vector-borne microbe interactions reveals pathogenicity mechanisms.Hart TM, Sonnert ND, Tang X, Chaurasia R, Allen PE, Hunt JR, Read CB, Johnson EE, Arora G, Dai Y, Cui Y, Chuang YM, Yu Q, Rahman MS, Mendes MT, Rolandelli A, Singh P, Tripathi AK, Ben Mamoun C, Caimano MJ, Radolf JD, Lin YP, Fingerle V, Margos G, Pal U, Johnson RM, Pedra JHF, Azad AF, Salje J, Dimopoulos G, Vinetz JM, Carlyon JA, Palm NW, Fikrig E, Ring AM. Cell. 2024 Jun 11; 2024 Jun 11. PMID: 38876107.
- nipalsMCIA: Flexible Multi-Block Dimensionality Reduction in R via Non-linear Iterative Partial Least Squares.Mattessich M, Reyna J, Aron E, Ay F, Kilmer M, Kleinstein SH, Konstorum A. bioRxiv. 2024 Jun 10; 2024 Jun 10. PMID: 38915554.
- High-throughput transcriptome profiling indicates ribosomal RNAs to be associated with resistance to immunotherapy in non-small cell lung cancer (NSCLC).Moutafi MK, Bates KM, Aung TN, Milian RG, Xirou V, Vathiotis IA, Gavrielatou N, Angelakis A, Schalper KA, Salichos L, Rimm DL. J Immunother Cancer. 2024 Jun 10; 2024 Jun 10. PMID: 38857914.
- Psychosocial burden of autoimmune blistering diseases: A comprehensive survey study.White MA, Hoffman VM, Yale M, Strong R, Tomayko MM. J Eur Acad Dermatol Venereol. 2024 Jun 4; 2024 Jun 4. PMID: 38837452.
- "Rounding Third Base and Heading Home": Arthritis & Rheumatology in 2024.Solomon DH, Kaplan MJ, Nigrovic PA, Bucala R. Arthritis Rheumatol. 2024 Jun; 2024 Apr 4. PMID: 38572586.
- Factors Associated With Long COVID: Insights From Two Nationwide Surveys.Wu Y, Sawano M, Wu Y, Shah RM, Bishop P, Iwasaki A, Krumholz HM. Am J Med. 2024 Jun; 2024 Mar 14. PMID: 38490304.
- Multicenter prospective blinded melanoma detection study with a handheld elastic scattering spectroscopy device.Hartman RI, Trepanowski N, Chang MS, Tepedino K, Gianacas C, McNiff JM, Fung M, Braghiroli NF, Grant-Kels JM. JAAD Int. 2024 Jun; 2023 Nov 15. PMID: 38371666.
- Metabolic fitness of IgA(+) plasma cells in the gut requires DOCK8.Zhang B, Chen S, Yin X, McBride CD, Gertie JA, Yurieva M, Bielecka AA, Hoffmann B, Travis Hinson J, Grassmann J, Xu L, Siniscalco ER, Soldatenko A, Hoyt L, Joseph J, Norton EB, Uthaman G, Palm NW, Liu E, Eisenbarth SC, Williams A. Mucosal Immunol. 2024 Jun; 2023 Dec 28. PMID: 38159726.
- Spatially resolved tissue imaging to analyze the tumor immune microenvironment: beyond cell-type densities.Lopez Janeiro A, Miraval Wong E, Jiménez-Sánchez D, Ortiz de Solorzano C, Lozano MD, Teijeira A, Schalper KA, Melero I, De Andrea CE. J Immunother Cancer. 2024 May 31; 2024 May 31. PMID: 38821717.
- Is Lipid Metabolism of Value in Cancer Research and Treatment? Part II: Role of Specialized Pro-Resolving Mediators in Inflammation, Infections, and Cancer.Babar MU, Nassar AF, Nie X, Zhang T, He J, Yeung J, Norris P, Ogura H, Muldoon A, Chen L, Libreros S. Metabolites. 2024 May 29; 2024 May 29. PMID: 38921449.
- Is Lipid Metabolism of Value in Cancer Research and Treatment? Part I- Lipid Metabolism in Cancer.Nassar AF, Nie X, Zhang T, Yeung J, Norris P, He J, Ogura H, Babar MU, Muldoon A, Libreros S, Chen L. Metabolites. 2024 May 29; 2024 May 29. PMID: 38921447.
- Deleting the mitochondrial respiration negative regulator MCJ enhances the efficacy of CD8(+) T cell adoptive therapies in pre-clinical studies.Wu MH, Valenca-Pereira F, Cendali F, Giddings EL, Pham-Danis C, Yarnell MC, Novak AJ, Brunetti TM, Thompson SB, Henao-Mejia J, Flavell RA, D'Alessandro A, Kohler ME, Rincon M. Nat Commun. 2024 May 24; 2024 May 24. PMID: 38789421.
- Macrophage-derived macrophage migration inhibitory factor mediates renal injury in anti-glomerular basement membrane glomerulonephritis.Yang H, Li J, Huang XR, Bucala R, Xu A, Lan HY. Front Immunol. 2024; 2024 May 23. PMID: 38846956.
- Enhancing in vivo cell and tissue targeting by modulation of polymer nanoparticles and macrophage decoys.Piotrowski-Daspit AS, Bracaglia LG, Eaton DA, Richfield O, Binns TC, Albert C, Gould J, Mortlock RD, Egan ME, Pober JS, Saltzman WM. Nat Commun. 2024 May 18; 2024 May 18. PMID: 38762483.
- Supervised latent factor modeling isolates cell-type-specific transcriptomic modules that underlie Alzheimer's disease progression.Hodgson L, Li Y, Iturria-Medina Y, Stratton JA, Wolf G, Krishnaswamy S, Bennett DA, Bzdok D. Commun Biol. 2024 May 17; 2024 May 17. PMID: 38760483.
- StrokeClassifier: ischemic stroke etiology classification by ensemble consensus modeling using electronic health records.Lee HJ, Schwamm LH, Sansing LH, Kamel H, de Havenon A, Turner AC, Sheth KN, Krishnaswamy S, Brandt C, Zhao H, Krumholz H, Sharma R. NPJ Digit Med. 2024 May 17; 2024 May 17. PMID: 38760474.
- A scalable and cost-efficient rRNA depletion approach to enrich RNAs for molecular biology investigations.Singh A, Xue A, Tai J, Mbadugha F, Obi P, Mascarenhas R, Tyagi A, Siena A, Chen YG. RNA. 2024 May 16; 2024 May 16. PMID: 38485192.
- Novel cell states arise in embryonic cells devoid of key reprogramming factors.Youlten SE, Miao L, Hoppe C, Boswell CW, Musaev D, Abdelmessih M, Krishnaswamy S, Tornini VA, Giraldez AJ. bioRxiv. 2024 May 15; 2024 May 15. PMID: 38798464.
- Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser.Jensen CG, Sumner JA, Kleinstein SH, Hoehn KB. J Immunol. 2024 May 15. PMID: 38557795.
- Control of Inflammatory Response by Tissue Microenvironment.Wu Z, Pope SD, Ahmed NS, Leung DL, Hajjar S, Yue Q, Anand DM, Kopp EB, Okin D, Ma W, Kagan JC, Hargreaves DC, Medzhitov R, Zhou X. bioRxiv. 2024 May 14; 2024 May 14. PMID: 38798655.
- Acute pulmonary injury in hematology patients supported with pathogen-reduced and conventional platelet components.Wheeler AP, Snyder EL, Refaai M, Cohn CS, Poisson J, Fontaine M, Sehl M, Nooka AK, Uhl L, Spinella PC, Fenelus M, Liles D, Coyle T, Becker J, Jeng M, Gehrie EA, Spencer BR, Young P, Johnson A, O'Brien JJ, Schiller GJ, Roback JD, Malynn E, Jackups R, Avecilla ST, Liu K, Bentow S, Varrone J, Benjamin RJ, Corash LM. Blood Adv. 2024 May 14. PMID: 38447116.
- Supervised fine-tuning of pre-trained antibody language models improves antigen specificity prediction.Wang M, Patsenker J, Li H, Kluger Y, Kleinstein SH. bioRxiv. 2024 May 13; 2024 May 13. PMID: 38798340.
- In the Eyes of the Beholder-New Mertk Knockout Mouse and Re-Evaluation of Phagocytosis versus Anti-Inflammatory Functions of MERTK.Ghosh S, Finnemann SC, Vollrath D, Rothlin CV. Int J Mol Sci. 2024 May 13; 2024 May 13. PMID: 38791338.
- The PAX LC Trial: A Decentralized, Phase 2, Randomized, Double-Blind Study of Nirmatrelvir/Ritonavir Compared with Placebo/Ritonavir for Long COVID.Krumholz HM, Sawano M, Bhattacharjee B, Caraballo C, Khera R, Li SX, Herrin J, Coppi A, Holub J, Henriquez Y, Johnson MA, Goddard TB, Rocco E, Hummel AC, Al Mouslmani M, Putrino DF, Carr KD, Carvajal-Gonzalez S, Charnas L, De Jesus M, Ziegler FW 3rd, Iwasaki A. Am J Med. 2024 May 10; 2024 May 10. PMID: 38735354.
- Adverse Food Reactions: Physiological and Ecological Perspectives.Korn LL, Kutyavin VI, Bachtel ND, Medzhitov R. Annu Rev Nutr. 2024 May 9; 2024 May 9. PMID: 38724028.
- Loss of function of metabolic traits in typhoidal Salmonella without apparent genome degradation.Machado LFM, Galán JE. mBio. 2024 May 8; 2024 Apr 4. PMID: 38572992.
- Nanoparticle Retinoic Acid-Inducible Gene I Agonist for Cancer Immunotherapy.Wang-Bishop L, Wehbe M, Pastora LE, Yang J, Kimmel BR, Garland KM, Becker KW, Carson CS, Roth EW, Gibson-Corley KN, Ulkoski D, Krishnamurthy V, Fedorova O, Richmond A, Pyle AM, Wilson JT. ACS Nano. 2024 May 7; 2024 Apr 23. PMID: 38652829.
- TREM2 function in glioblastoma immune microenvironment: Can we distinguish reality from illusion?Ghosh S, Rothlin CV. Neuro Oncol. 2024 May 3. PMID: 38290471.
- Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development.Wu HF, Saito-Diaz K, Huang CW, McAlpine JL, Seo DE, Magruder DS, Ishan M, Bergeron HC, Delaney WH, Santori FR, Krishnaswamy S, Hart GW, Chen YW, Hogan RJ, Liu HX, Ivanova NB, Zeltner N. Cell Stem Cell. 2024 May 2; 2024 Apr 11. PMID: 38608707.
- A supervised Bayesian factor model for the identification of multi-omics signatures.Gygi JP, Konstorum A, Pawar S, Aron E, Kleinstein SH, Guan L. Bioinformatics. 2024 May 2. PMID: 38603606.
- Genetic mapping across autoimmune diseases reveals shared associations and mechanisms.Lincoln MR, Connally N, Axisa PP, Gasperi C, Mitrovic M, van Heel D, Wijmenga C, Withoff S, Jonkers IH, Padyukov L, Rich SS, Graham RR, Gaffney PM, Langefeld CD, Vyse TJ, Hafler DA, Chun S, Sunyaev SR, Cotsapas C. Nat Genet. 2024 May; 2024 May 13. PMID: 38741015.
- Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality.Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Haddad EK, Reed EF, Kraft M, McComsey GA, Metcalf JP, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar WL, Maecker HT, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Sekaly RP, Ehrlich LI, Fourati S, Peters B, Kleinstein SH, Guan L. J Clin Invest. 2024 May 1; 2024 May 1. PMID: 38690733.
- Beyond antiviral: role of IFN-I in brain development.Baker CA, Iwasaki A. Trends Immunol. 2024 May; 2024 Apr 20. PMID: 38644134.
- IL-1 receptor 1 signaling shapes the development of viral antigen-specific CD4(+) T cell responses following COVID-19 mRNA vaccination.Park HJ, Shin MS, Shin JJ, Kim H, Kang B, Par-Young J, Unlu S, Afinogenova Y, Catanzaro J, Young J, Kim M, Lee SJ, Jeon S, You S, Racke MK, Bucala R, Kang I. EBioMedicine. 2024 May; 2024 Apr 18. PMID: 38640835.
- Randomized Phase II Trial of Imiquimod with or without 9-Valent HPV Vaccine versus Observation in Patients with High-grade Pre-neoplastic Cervical Lesions (NCT02864147).Sheth SS, Oh JE, Bellone S, Siegel ER, Greenman M, Mutlu L, McNamara B, Pathy S, Clark M, Azodi M, Altwerger G, Andikyan V, Huang G, Ratner E, Kim DJ, Iwasaki A, Levi AW, Buza N, Hui P, Flaherty S, Schwartz PE, Santin AD. Clin Cancer Res. 2024 May 1. PMID: 38592381.
- Posttransplant Tertiary Lymphoid Organs.Ruddle NH. Transplantation. 2024 May 1; 2023 Nov 2. PMID: 37917987.
- Intranasal neomycin evokes broad-spectrum antiviral immunity in the upper respiratory tract.Mao T, Kim J, Peña-Hernández MA, Valle G, Moriyama M, Luyten S, Ott IM, Gomez-Calvo ML, Gehlhausen JR, Baker E, Israelow B, Slade M, Sharma L, Liu W, Ryu C, Korde A, Lee CJ, Silva Monteiro V, Lucas C, Dong H, Yang Y, Gopinath S, Wilen CB, Palm N, Dela Cruz CS, Iwasaki A. Proc Natl Acad Sci U S A. 2024 Apr 30; 2024 Apr 22. PMID: 38648490.
- Macrophage Migration Inhibitory Factor (MIF) and D-Dopachrome Tautomerase (DDT): Pathways to Tumorigenesis and Therapeutic Opportunities.Valdez CN, Sánchez-Zuno GA, Bucala R, Tran TT. Int J Mol Sci. 2024 Apr 29; 2024 Apr 29. PMID: 38732068.
- Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity.Zhang T, Yu W, Cheng X, Yeung J, Ahumada V, Norris PC, Pearson MJ, Yang X, van Deursen W, Halcovich C, Nassar A, Vesely MD, Zhang Y, Zhang J, Ji L, Flies DB, Liu L, Langermann S, LaRochelle WJ, Humphrey R, Zhao D, Zhang Q, Zhang J, Gu R, Schalper KA, Sanmamed MF, Chen L. Sci Immunol. 2024 Apr 26; 2024 Apr 26. PMID: 38669316.
- Exploring new perspectives in immunology.Medzhitov R, Iwasaki A. Cell. 2024 Apr 25. PMID: 38670066.
- Long COVID Characteristics and Experience: A Descriptive Study from the Yale LISTEN Research Cohort.Sawano M, Wu Y, Shah RM, Zhou T, Arun AS, Khosla P, Kaleem S, Vashist A, Bhattacharjee B, Ding Q, Lu Y, Caraballo C, Warner F, Huang C, Herrin J, Putrino D, Michelsen T, Fisher L, Adinig C, Iwasaki A, Krumholz HM. Am J Med. 2024 Apr 23; 2024 Apr 23. PMID: 38663793.
- Proof-of-concept studies with a computationally designed M(pro) inhibitor as a synergistic combination regimen alternative to Paxlovid.Papini C, Ullah I, Ranjan AP, Zhang S, Wu Q, Spasov KA, Zhang C, Mothes W, Crawford JM, Lindenbach BD, Uchil PD, Kumar P, Jorgensen WL, Anderson KS. Proc Natl Acad Sci U S A. 2024 Apr 23; 2024 Apr 15. PMID: 38621119.
- Sensitive bispecific chimeric T cell receptors for cancer therapy.Simon S, Bugos G, Prins R, Rajan A, Palani A, Heyer K, Stevens A, Zeng L, Thompson K, Price JP, Kluesner MK, Jaeger-Ruckstuhl C, Shabaneh TB, Olson JM, Su X, Riddell SR. Res Sq. 2024 Apr 22; 2024 Apr 22. PMID: 38746248.
- Factors Associated with Long COVID Recovery among US Adults.Shah KM, Shah RM, Sawano M, Wu Y, Bishop P, Iwasaki A, Krumholz HM. Am J Med. 2024 Apr 21; 2024 Apr 21. PMID: 38649004.
- MIF-Modulated Spinal Proteins Associated with Persistent Bladder Pain: A Proteomics Study.Ye S, Agalave NM, Ma F, Mahmood DFD, Al-Grety A, Khoonsari PE, Leng L, Svensson CI, Bucala R, Kultima K, Vera PL. Int J Mol Sci. 2024 Apr 19; 2024 Apr 19. PMID: 38674069.
- Vascular mimicry as a facilitator of melanoma brain metastasis.Provance OK, Oria VO, Tran TT, Caulfield JI, Zito CR, Aguirre-Ducler A, Schalper KA, Kluger HM, Jilaveanu LB. Cell Mol Life Sci. 2024 Apr 18; 2024 Apr 18. PMID: 38635031.
- Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology.Phan HV, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns CB, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N, Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR. Sci Transl Med. 2024 Apr 17; 2024 Apr 17. PMID: 38630846.
- Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties.Shin JH, Park J, Lim J, Jeong J, Dinesh RK, Maher SE, Hong JY, Wysolmerski J, Choi J, Bothwell ALM. bioRxiv. 2024 Apr 15; 2024 Apr 15. PMID: 38659853.
- Highly Reactive Group I Introns Ubiquitous in Pathogenic Fungi.Liu T, Pyle AM. J Mol Biol. 2024 Apr 15; 2024 Mar 5. PMID: 38447889.
- Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease.Zhou X, Shen X, Johnson JS, Spakowicz DJ, Agnello M, Zhou W, Avina M, Honkala A, Chleilat F, Chen SJ, Cha K, Leopold S, Zhu C, Chen L, Lyu L, Hornburg D, Wu S, Zhang X, Jiang C, Jiang L, Jiang L, Jian R, Brooks AW, Wang M, Contrepois K, Gao P, Rose SMS, Tran TDB, Nguyen H, Celli A, Hong BY, Bautista EJ, Dorsett Y, Kavathas PB, Zhou Y, Sodergren E, Weinstock GM, Snyder MP. Cell Host Microbe. 2024 Apr 10; 2024 Mar 12. PMID: 38479397.
- DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells.Ren X, Liu Q, Zhou P, Zhou T, Wang D, Mei Q, Flavell RA, Liu Z, Li M, Pan W, Zhu S. Nat Commun. 2024 Apr 9; 2024 Apr 9. PMID: 38594251.
- Stem cell migration drives lung repair in living mice.Chioccioli M, Liu S, Magruder S, Tata A, Borriello L, McDonough JE, Konkimalla A, Kim SH, Nouws J, Gonzalez DG, Traub B, Ye X, Yang T, Entenberg DR, Krishnaswamy S, Hendry CE, Kaminski N, Tata PR, Sauler M. Dev Cell. 2024 Apr 8; 2024 Feb 19. PMID: 38377991.
- Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers.Boruah N, Hoyos D, Moses R, Hausler R, Desai H, Le AN, Good M, Kelly G, Raghavakaimal A, Tayeb M, Narasimhamurthy M, Doucette A, Gabriel P, Feldman MJ, Park J, de Rodas ML, Schalper KA, Goldfarb SB, Nayak A, Levine AJ, Greenbaum BD, Maxwell KN. bioRxiv. 2024 Apr 5; 2024 Apr 5. PMID: 38617260.
- Gene trajectory inference for single-cell data by optimal transport metrics.Qu R, Cheng X, Sefik E, Stanley Iii JS, Landa B, Strino F, Platt S, Garritano J, Odell ID, Coifman R, Flavell RA, Myung P, Kluger Y. Nat Biotechnol. 2024 Apr 5; 2024 Apr 5. PMID: 38580861.
- Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages.Liebold I, Al Jawazneh A, Casar C, Lanzloth C, Leyk S, Hamley M, Wong MN, Kylies D, Gräfe SK, Edenhofer I, Aranda-Pardos I, Kriwet M, Haas H, Krause J, Hadjilaou A, Schromm AB, Richardt U, Eggert P, Tappe D, Weidemann SA, Ghosh S, Krebs CF, A-Gonzalez N, Worthmann A, Lohse AW, Huber S, Rothlin CV, Puelles VG, Jacobs T, Gagliani N, Bosurgi L. Science. 2024 Apr 5; 2024 Apr 5. PMID: 38574142.
- Defining and benchmarking open problems in single-cell analysis.Luecken MD, Gigante S, Burkhardt DB, Cannoodt R, Strobl DC, Markov NS, Zappia L, Palla G, Lewis W, Dimitrov D, Vinyard ME, Magruder DS, Andersson A, Dann E, Qin Q, Otto DJ, Klein M, Botvinnik OB, Deconinck L, Waldrant K, Bloom JM, Pisco AO, Saez-Rodriguez J, Wulsin D, Pinello L, Saeys Y, Theis FJ, Krishnaswamy S. Res Sq. 2024 Apr 4; 2024 Apr 4. PMID: 38645152.
- Clinical Predictors of Survival in Patients With BRAFV600-Mutated Metastatic Melanoma Treated With Combined BRAF and MEK Inhibitors After Immune Checkpoint Inhibitors.Kahn AM, Perry CJ, Etts K, Kluger H, Sznol M. Oncologist. 2024 Apr 4. PMID: 37971411.
- Melanocortin-1 Receptor Expression as a Marker of Progression in Melanoma.Su DG, Djureinovic D, Schoenfeld D, Marquez-Nostra B, Olino K, Jilaveanu L, Kluger H. JCO Precis Oncol. 2024 Apr. PMID: 38662983.
- A host-microbiota interactome reveals extensive transkingdom connectivity.Sonnert ND, Rosen CE, Ghazi AR, Franzosa EA, Duncan-Lowey B, González-Hernández JA, Huck JD, Yang Y, Dai Y, Rice TA, Nguyen MT, Song D, Cao Y, Martin AL, Bielecka AA, Fischer S, Guan C, Oh J, Huttenhower C, Ring AM, Palm NW. Nature. 2024 Apr; 2024 Mar 20. PMID: 38509360.
- HIF-1α Mediates Immunosuppression and Chemoresistance in Colorectal Cancer by Inhibiting CXCL9, -10 and -11.Su Y, Liu J, Tian Y, Dong H, Shi M, Zhang J, Li W, Huang Q, Xiang N, Wang C, Liu J, He L, Hu L, Haberman AM, Liu H, Yang X. Biomed Pharmacother. 2024 Apr; 2024 Mar 13. PMID: 38484558.
- Compartmentalized ocular lymphatic system mediates eye-brain immunity.Yin X, Zhang S, Lee JH, Dong H, Mourgkos G, Terwilliger G, Kraus A, Geraldo LH, Poulet M, Fischer S, Zhou T, Mohammed FS, Zhou J, Wang Y, Malloy S, Rohner N, Sharma L, Salinas I, Eichmann A, Thomas JL, Saltzman WM, Huttner A, Zeiss C, Ring A, Iwasaki A, Song E. Nature. 2024 Apr; 2024 Feb 28. PMID: 38418880.
- Cutting Edge: Phagosome-associated Autophagosomes Containing Antigens and Proteasomes Drive TAP-Independent Cross-Presentation.Sengupta D, Galicia-Pereyra R, Han P, Graham M, Liu X, Arshad N, Cresswell P. J Immunol. 2024 Apr 1. PMID: 38353614.
- A small molecule macrophage migration inhibitory factor agonist ameliorates age-related myocardial intolerance to ischemia-reperfusion insults via metabolic regulation.Wang H, Slotabec L, Didik S, Li Z, Leng L, Zhao B, Bucala R, Li J. Metabolism. 2024 Apr; 2024 Jan 15. PMID: 38232801.
- IL-10 dampens antitumor immunity and promotes liver metastasis via PD-L1 induction.Shiri AM, Zhang T, Bedke T, Zazara DE, Zhao L, Lücke J, Sabihi M, Fazio A, Zhang S, Tauriello DVF, Batlle E, Steglich B, Kempski J, Agalioti T, Nawrocki M, Xu Y, Riecken K, Liebold I, Brockmann L, Konczalla L, Bosurgi L, Mercanoglu B, Seeger P, Küsters N, Lykoudis PM, Heumann A, Arck PC, Fehse B, Busch P, Grotelüschen R, Mann O, Izbicki JR, Hackert T, Flavell RA, Gagliani N, Giannou AD, Huber S. J Hepatol. 2024 Apr; 2023 Dec 30. PMID: 38160941.