Cancer Immunology Recent Publications

2023

Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice.Nickerson KM, Smita S, Hoehn KB, Marinov AD, Thomas KB, Kos JT, Yang Y, Bastacky SI, Watson CT, Kleinstein SH, Shlomchik MJ. J Exp Med. 2023 May 1; 2023 Feb 24. PMID: 36828389.
Why we need a deeper understanding of the pathophysiology of long COVID.Iwasaki A, Putrino D. Lancet Infect Dis. 2023 Apr; 2023 Feb 14. PMID: 36967698.
Effects of androgen excess and body mass index on endothelial function in women with polycystic ovary syndrome.Berbrier DE, Leone CA, Adler TE, Bender JR, Taylor HS, Stachenfeld NS, Usselman CW. J Appl Physiol (1985). 2023 Apr 1; 2023 Mar 2. PMID: 36861670.
Mature B cells and mesenchymal stem cells control emergency myelopoiesis.Lim VY, Feng X, Miao R, Zehentmeier S, Ewing-Crystal N, Lee M, Tumanov AV, Oh JE, Iwasaki A, Wang A, Choi J, Pereira JP. Life Sci Alliance. 2023 Apr; 2023 Jan 30. PMID: 36717247.
Outcomes With Combination Pembrolizumab and Axitinib in Second and Further Line Treatment of Metastatic Renal Cell Carcinoma.Dizman N, Austin M, Considine B, Jessel S, Schoenfeld D, Merl MY, Hurwitz M, Sznol M, Kluger H. Clin Genitourin Cancer. 2023 Apr; 2023 Jan 12. PMID: 36681606.
Hedgehog-induced ZFYVE21 promotes chronic vascular inflammation by activating NLRP3 inflammasomes in T cells.Jiang B, Wang S, Song G, Jiang Q, Fan M, Fang C, Li X, Soh CL, Manes TD, Cheru N, Qin L, Ren P, Jortner B, Wang Q, Quaranta E, Yoo P, Geirsson A, Davis RP, Tellides G, Pober JS, Jane-Wit D. Sci Signal. 2023 Mar 21; 2023 Mar 21. PMID: 36943921.
Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation.Zheng D, Mohapatra G, Kern L, He Y, Shmueli MD, Valdés-Mas R, Kolodziejczyk AA, Próchnicki T, Vasconcelos MB, Schorr L, Hertel F, Lee YS, Rufino MC, Ceddaha E, Shimshy S, Hodgetts RJ, Dori-Bachash M, Kleimeyer C, Goldenberg K, Heinemann M, Stettner N, Harmelin A, Shapiro H, Puschhof J, Chen M, Flavell RA, Latz E, Merbl Y, Abdeen SK, Elinav E. Nat Immunol. 2023 Mar 20; 2023 Mar 20. PMID: 36941399.
Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms.Taghi Khani A, Kumar A, Sanchez Ortiz A, Radecki KC, Aramburo S, Lee SJ, Hu Z, Damirchi B, Lorenson MY, Wu X, Gu Z, Stohl W, Sanz I, Meffre E, Müschen M, Forman SJ, Koff JL, Walker AM, Swaminathan S. Commun Biol. 2023 Mar 20; 2023 Mar 20. PMID: 36941341.
Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120.Richard J, Prévost J, Bourassa C, Brassard N, Boutin M, Benlarbi M, Goyette G, Medjahed H, Gendron-Lepage G, Gaudette F, Chen HC, Tolbert WD, Smith AB 3rd, Pazgier M, Dubé M, Clark A, Mothes W, Kaufmann DE, Finzi A. Cell Chem Biol. 2023 Mar 17; 2023 Mar 17. PMID: 36958337.
Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome.de Jesus AA, Chen G, Yang D, Brdicka T, Ruth NM, Bennin D, Cebecauerova D, Malcova H, Freeman H, Martin N, Svojgr K, Passo MH, Bhuyan F, Alehashemi S, Rastegar AT, Uss K, Kardava L, Marrero B, Duric I, Omoyinmi E, Peldova P, Lee CR, Kleiner DE, Hadigan CM, Hewitt SM, Pittaluga S, Carmona-Rivera C, Calvo KR, Shah N, Balascakova M, Fink DL, Kotalova R, Parackova Z, Peterkova L, Kuzilkova D, Campr V, Sramkova L, Biancotto A, Brooks SR, Manes C, Meffre E, Harper RL, Kuehn H, Kaplan MJ, Brogan P, Rosenzweig SD, Merchant M, Deng Z, Huttenlocher A, Moir SL, Kuhns DB, Boehm M, Skvarova Kramarzova K, Goldbach-Mansky R. Nat Commun. 2023 Mar 17; 2023 Mar 17. PMID: 36932076.
A protocol for capturing RNA-sensing innate immune receptors in multiple conformations by single-particle cryo-EM.Wang W, Fedorova O, Pyle AM. STAR Protoc. 2023 Mar 14; 2023 Mar 14. PMID: 36920909.
Correction to: Real-Life Barriers to Diagnosis of Early Mycosis Fungoides: An International Expert Panel Discussion.Hodak E, Geskin L, Guenova E, Ortiz-Romero PL, Willemze R, Zheng J, Cowan R, Foss F, Mangas C, Querfeld C. Am J Clin Dermatol. 2023 Mar 14; 2023 Mar 14. PMID: 36914911.
Cost-effectiveness of chimeric antigen receptor T-cell therapy in adults with relapsed or refractory follicular lymphoma.Potnis KC, Di M, Isufi I, Gowda L, Seropian SE, Foss FM, Forman HP, Huntington SF. Blood Adv. 2023 Mar 14. PMID: 36342852.
Cell circuits between leukemic cells and mesenchymal stem cells block lymphopoiesis by activating lymphotoxin beta receptor signaling.Feng X, Sun R, Lee M, Chen X, Guo S, Geng H, Müschen M, Choi J, Pereira JP. Elife. 2023 Mar 13; 2023 Mar 13. PMID: 36912771.
Current landscape of translational and clinical research in myelodysplastic syndromes/neoplasms (MDS): Proceedings from the 1(st) International Workshop on MDS (iwMDS) Of the International Consortium for MDS (icMDS).Bewersdorf JP, Xie Z, Bejar R, Borate U, Boultwood J, Brunner AM, Buckstein R, Carraway HE, Churpek JE, Daver NG, Porta MGD, DeZern AE, Fenaux P, Figueroa ME, Gore SD, Griffiths EA, Halene S, Hasserjian RP, Hourigan CS, Kim TK, Komrokji R, Kuchroo VK, List AF, Loghavi S, Majeti R, Odenike O, Patnaik MM, Platzbecker U, Roboz GJ, Sallman DA, Santini V, Sanz G, Sekeres MA, Stahl M, Starczynowski DT, Steensma DP, Taylor J, Abdel-Wahab O, Xu ML, Savona MR, Wei AH, Zeidan AM. Blood Rev. 2023 Mar 11; 2023 Mar 11. PMID: 36934059.
Cognitive Bias in Pathology, as Exemplified in Dermatopathology.Ko CJ, Glusac EJ. Hum Pathol. 2023 Mar 9; 2023 Mar 9. PMID: 36906184.
SARS-CoV-2 mRNA vaccines decouple anti-viral immunity from humoral autoimmunity.Jaycox JR, Lucas C, Yildirim I, Dai Y, Wang EY, Monteiro V, Lord S, Carlin J, Kita M, Buckner JH, Ma S, Campbell M, Ko A, Omer S, Lucas CL, Speake C, Iwasaki A, Ring AM. Nat Commun. 2023 Mar 9; 2023 Mar 9. PMID: 36894554.
Humanized MISTRG as a preclinical in vivo model to study human neutrophil-mediated immune processes.Martinez-Sanz P, Laurent ARG, Slot E, Hoogenboezem M, Bąbała N, van Bruggen R, Rongvaux A, Flavell RA, Tytgat GAM, Franke K, Matlung HL, Kuijpers TW, Amsen D, Karrich JJ. Front Immunol. 2023; 2023 Mar 8. PMID: 36969261.
Cytokines in New-Onset Refractory Status Epilepticus Predict Outcomes.Hanin A, Cespedes J, Dorgham K, Pulluru Y, Gopaul M, Gorochov G, Hafler DA, Navarro V, Gaspard N, Hirsch LJ. Ann Neurol. 2023 Mar 5; 2023 Mar 5. PMID: 36871188.
Type 2 Dendritic Cells Orchestrate a Local Immune Circuit to Confer Antimetastatic Immunity.Weizman OE, Luyten S, Krykbaeva I, Song E, Mao T, Bosenberg M, Iwasaki A. J Immunol. 2023 Mar 3; 2023 Mar 3. PMID: 36881866.
Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.Hackstein CP, Spitzer J, Symeonidis K, Horvatic H, Bedke T, Steglich B, Klein S, Assmus LM, Odainic A, Szlapa J, Kessler N, Beyer M, Schmithausen R, Latz E, Flavell RA, Garbi N, Kurts C, Kümmerer BM, Trebicka J, Roers A, Huber S, Schmidt SV, Knolle PA, Abdullah Z. J Hepatol. 2023 Mar 2; 2023 Mar 2. PMID: 36870611.
Germline genetic variants are associated with development of insulin-dependent diabetes in cancer patients treated with immune checkpoint inhibitors.Caulfield JI, Aizenbud L, Perdigoto AL, Meffre E, Jilaveanu L, Michalek DA, Rich SS, Aizenbud Y, Adeniran A, Herold KC, Austin MR, Kluger H. J Immunother Cancer. 2023 Mar. PMID: 36898736.
Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection.Wei J, Patil A, Collings CK, Alfajaro MM, Liang Y, Cai WL, Strine MS, Filler RB, DeWeirdt PC, Hanna RE, Menasche BL, Ökten A, Peña-Hernández MA, Klein J, McNamara A, Rosales R, McGovern BL, Luis Rodriguez M, García-Sastre A, White KM, Qin Y, Doench JG, Yan Q, Iwasaki A, Zwaka TP, Qi J, Kadoch C, Wilen CB. Nat Genet. 2023 Mar; 2023 Mar 9. PMID: 36894709.
Response to: Elevated L1 expression in ataxia telangiectasia likely explained by an RNA-seq batch effect.Takahashi T, Stoiljkovic M, Song E, Gao XB, Yasumoto Y, Kudo E, Carvalho F, Kong Y, Park A, Shanabrough M, Szigeti-Buck K, Liu ZW, Kristant A, Zhang Y, Sulkowski P, Glazer PM, Kaczmarek LK, Horvath TL, Iwasaki A. Neuron. 2023 Mar 1. PMID: 36863323.
A rare presentation of cutaneous T-cell lymphoma mimicking morphea.Yu B, Kim SR, Roy SF, Girardi M. JAAD Case Rep. 2023 Mar; 2023 Jan 26. PMID: 36860808.
RSCanner: rapid assessment and visualization of RNA structure content.Mahadeshwar G, Tavares RCA, Wan H, Perry ZR, Pyle AM. Bioinformatics. 2023 Mar 1. PMID: 36857576.
A rare case of viral-associated trichodysplasia spinulosa in a patient with chronic lymphocytic leukemia.Choi R, Bhullar S, McNiff J, Persico J, Leventhal J. Int J Womens Dermatol. 2023 Mar; 2023 Feb 23. PMID: 36846188.
DNA methylation of the promoter region at the CREB1 binding site is a mechanism for the epigenetic regulation of brain-specific PKMζ.Pramio DT, Vieceli FM, Varella-Branco E, Goes CP, Kobayashi GS, da Silva Pelegrina DV, de Moraes BC, El Allam A, De Kumar B, Jara G, Farfel JM, Bennett DA, Kundu S, Viapiano MS, Reis EM, de Oliveira PSL, Dos Santos E Passos-Bueno MR, Rothlin CV, Ghosh S, Schechtman D. Biochim Biophys Acta Gene Regul Mech. 2023 Mar; 2023 Jan 20. PMID: 36682583.
CD137 (4-1BB)-Based Cancer Immunotherapy on Its 25th Anniversary.Melero I, Sanmamed MF, Glez-Vaz J, Luri-Rey C, Wang J, Chen L. Cancer Discov. 2023 Mar 1. PMID: 36576322.
Unmeasured factors are associated with the use of completion lymph node dissection (CLND) in melanoma.Leonard LD, Beaty L, Thomas M, Quinn C, Colborn KL, de Araujo TB, Torphy RJ, Assumpção LR, Olino K, Studts CR, Rodriguez Franco S, McCarter M, Stewart C, Gleisner AL. J Surg Oncol. 2023 Mar; 2022 Dec 1. PMID: 36453464.
Interface change in early mycosis fungoides: A potential mimicker of benign dermatoses.Tsang M, McNiff JM. J Cutan Pathol. 2023 Mar; 2022 Dec 21. PMID: 36444501.
MR Imaging-Based In Vivo Macrophage Imaging to Monitor Immune Response after Radiofrequency Ablation of the Liver.Santana JG, Petukhova-Greenstein A, Gross M, Hyder F, Pekurovsky V, Gottwald LA, Boustani A, Walsh JJ, Kucukkaya AS, Malpani R, Madoff DC, Goldberg SN, Ahmed M, Joshi N, Coman D, Chapiro J. J Vasc Interv Radiol. 2023 Mar; 2022 Nov 21. PMID: 36423815.
Indoor Versus Outdoor: Does Occupational Sunlight Exposure Increase Melanoma Risk? A Systematic Review.Maduka RC, Tai K, Gonsai R, DeWalt N, Chetty A, Brackett A, Olino K, Schneider EB, Ahuja V. J Surg Res. 2023 Mar; 2022 Nov 21. PMID: 36423476.
Acute Epstein-Barr virus infection resembling cutaneous T-cell lymphoma.Fan R, Baker C, Glusac EJ, Xu ML, Gru AA, Cohen JM. J Cutan Pathol. 2023 Mar; 2022 Nov 23. PMID: 36349388.
Dermatopathologic features of cutaneous squamous cell carcinoma and actinic keratosis: Consensus criteria and proposed reporting guidelines.Christensen RE, Elston DM, Worley B, Dirr MA, Anvery N, Kang BY, Bahrami S, Brodell RT, Cerroni L, Elston C, Ferringer T, Hurley MY, Garton K, Lee JSS, Liu Y, Maize JC, McNiff JM, Rapini RP, Sangueza OP, Shea CR, Zhou C, Alam M. J Am Acad Dermatol. 2023 Feb 24; 2023 Feb 24. PMID: 36841336.
Targeting the Inducible T-cell Costimulator (ICOS) in patients with Relapsed/Refractory T-Follicular Helper Phenotype Peripheral T-Cell and Angioimmunoblastic T-Cell Lymphoma.Chavez JC, Foss FM, William BM, Brammer JE, Smith SM, Prica A, Zain JM, Tuscano JM, Shah H, Mehta-Shah N, Ramakrishnan Geethakumari PR, Wang BX, Zantinge S, Wang L, Zhang L, Boutrin A, Zhao W, Cheng L, Standifer N, Hewitt L, Enowtambong E, Shao W, Sharma S, Carlesso G, Moscow JA, Siu LL. Clin Cancer Res. 2023 Feb 24; 2023 Feb 24. PMID: 36826995.
NLRP6 deficiency expands a novel CD103(+) B cell population that confers immune tolerance in NOD mice.Pearson JA, Peng J, Huang J, Yu X, Tai N, Hu Y, Sha S, Flavell RA, Zhao H, Wong FS, Wen L. Front Immunol. 2023; 2023 Feb 23. PMID: 36911699.
High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq.Liu Y, DiStasio M, Su G, Asashima H, Enninful A, Qin X, Deng Y, Nam J, Gao F, Bordignon P, Cassano M, Tomayko M, Xu M, Halene S, Craft JE, Hafler D, Fan R. Nat Biotechnol. 2023 Feb 23; 2023 Feb 23. PMID: 36823353.
Lenvatinib or anti-VEGF in combination with anti-PD-1 differentially augments anti-tumor activity in melanoma.Tran TT, Caulfield JI, Zhang L, Schoenfeld DA, Djureinovic D, Chiang VL, Oria VO, Weiss SA, Olino K, Jilaveanu LB, Kluger HM. JCI Insight. 2023 Feb 23; 2023 Feb 23. PMID: 36821392.
IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii.Clark JT, Weizman OE, Aldridge DL, Shallberg LA, Eberhard J, Lanzar Z, Wasche D, Huck JD, Zhou T, Ring AM, Hunter CA. Cell Rep. 2023 Feb 22; 2023 Feb 22. PMID: 36827187.
Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.Emmenegger M, De Cecco E, Lamparter D, Jacquat RPB, Riou J, Menges D, Ballouz T, Ebner D, Schneider MM, Morales IC, Doğançay B, Guo J, Wiedmer A, Domange J, Imeri M, Moos R, Zografou C, Batkitar L, Madrigal L, Schneider D, Trevisan C, Gonzalez-Guerra A, Carrella A, Dubach IL, Xu CK, Meisl G, Kosmoliaptsis V, Malinauskas T, Burgess-Brown N, Owens R, Hatch S, Mongkolsapaya J, Screaton GR, Schubert K, Huck JD, Liu F, Pojer F, Lau K, Hacker D, Probst-Müller E, Cervia C, Nilsson J, Boyman O, Saleh L, Spanaus K, von Eckardstein A, Schaer DJ, Ban N, Tsai CJ, Marino J, Schertler GFX, Ebert N, Thiel V, Gottschalk J, Frey BM, Reimann RR, Hornemann S, Ring AM, Knowles TPJ, Puhan MA, Althaus CL, Xenarios I, Stuart DI, Aguzzi A. iScience. 2023 Feb 17; 2023 Jan 4. PMID: 36619367.
Age-dependent impairment in antibody responses elicited by a homologous CoronaVac booster dose.Filardi BA, Monteiro VS, Schwartzmann PV, do Prado Martins V, Zucca LER, Baiocchi GC, Malik AA, Silva J, Hahn AM, Chen NFG, Pham K, Pérez-Then E, Miric M, Brache V, Cochon L, Larocca RA, Mendez RDR, Bardini Silveira D, Pinto AR, Croda J, Yildirim I, Omer SB, Ko AI, Vermund SH, Grubaugh ND, Iwasaki A, Lucas C, Vogels CBF, Breban M, Koch TR, Chaguza C, Tikhonova I, Castaldi C, Mane S, De Kumar B, Ferguson D, Kerantzas N, Peaper D, Landry ML, Schulz W. Sci Transl Med. 2023 Feb 15; 2023 Feb 15. PMID: 36791210.
PRAME immunohistochemistry can distinguish melanocytic pseudonests of lichenoid reactions from melanoma in situ.Roy SF, Panse G, McNiff JM. J Cutan Pathol. 2023 Feb 15; 2023 Feb 15. PMID: 36789669.
Differences in the immunogenicity of engineered circular RNAs.Tai J, Chen YG. J Mol Cell Biol. 2023 Feb 14; 2023 Feb 14. PMID: 36787893.
Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells.Sacirbegovic F, Günther M, Greco A, Zhao D, Wang X, Zhou M, Rosenberger S, Oberbarnscheidt MH, Held W, McNiff J, Jain D, Höfer T, Shlomchik WD. Immunity. 2023 Feb 14; 2023 Jan 30. PMID: 36720219.
Integrated transcriptome and trajectory analysis of cutaneous T-cell lymphoma identifies putative precancer populations.Ren J, Qu R, Rahman NT, Lewis JM, King ALO, Liao X, Mirza FN, Carlson KR, Huang Y, Gigante S, Evans B, Rajendran BK, Xu S, Wang G, Foss FM, Damsky W, Kluger Y, Krishnaswamy S, Girardi M. Blood Adv. 2023 Feb 14. PMID: 35947128.
Survival, Durable Tumor Remission, and Long-Term Safety in Patients With Advanced Melanoma Receiving Nivolumab.Topalian SL, Sznol M, McDermott DF, Kluger HM, Carvajal RD, Sharfman WH, Brahmer JR, Lawrence DP, Atkins MB, Powderly JD, Leming PD, Lipson EJ, Puzanov I, Smith DC, Taube JM, Wigginton JM, Kollia GD, Gupta A, Pardoll DM, Sosman JA, Hodi FS. J Clin Oncol. 2023 Feb 10. PMID: 36750016.
Metabolic reprogramming by immune-responsive gene 1 up-regulation improves donor heart preservation and function.Lei I, Huang W, Noly PE, Naik S, Ghali M, Liu L, Pagani FD, Abou El Ela A, Pober JS, Pitt B, Platt JL, Cascalho M, Wang Z, Chen YE, Mortensen RM, Tang PC. Sci Transl Med. 2023 Feb 8; 2023 Feb 8. PMID: 36753565.
Autoantibodies are highly prevalent in non-SARS-CoV-2 respiratory infections and critical illness.Feng A, Yang EY, Moore AR, Dhingra S, Chang SE, Yin X, Pi R, Mack EK, Völkel S, Geßner R, Gündisch M, Neubauer A, Renz H, Tsiodras S, Fragkou PC, Asuni AA, Levitt JE, Wilson JG, Leong M, Lumb JH, Mao R, Pinedo K, Roque J, Richards CM, Stabile M, Swaminathan G, Salagianni ML, Triantafyllia V, Bertrams W, Blish CA, Carette JE, Frankovich J, Meffre E, Nadeau KC, Singh U, Wang TT, Luning Prak ET, Herold S, Andreakos E, Schmeck B, Skevaki C, Rogers AJ, Utz PJ. JCI Insight. 2023 Feb 8; 2023 Feb 8. PMID: 36752204.
Serum Neutralizing Antibody Titers 12 Months After Coronavirus Disease 2019 Messenger RNA Vaccination: Correlation to Clinical Variables in an Adult, US Population.Zhao M, Slotkin R, Sheth AH, Pischel L, Kyriakides TC, Emu B, McNamara C, Shi Q, Delgobbo J, Xu J, Marhoffer E, Mercer-Falkoff A, Holleck J, Ardito D, Sutton RE, Gupta S. Clin Infect Dis. 2023 Feb 8. PMID: 35639598.
Malignant Melanoma in Older Adults: Different Patient or Different Disease?Sasson DC, Smetona JT, Parsaei Y, Papageorge M, Ariyan S, Olino K, Clune J. Cureus. 2023 Feb; 2023 Feb 7. PMID: 36909026.
Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs.Côrte-Real BF, Hamad I, Arroyo Hornero R, Geisberger S, Roels J, Van Zeebroeck L, Dyczko A, van Gisbergen MW, Kurniawan H, Wagner A, Yosef N, Weiss SNY, Schmetterer KG, Schröder A, Krampert L, Haase S, Bartolomaeus H, Hellings N, Saeys Y, Dubois LJ, Brenner D, Kempa S, Hafler DA, Stegbauer J, Linker RA, Jantsch J, Müller DN, Kleinewietfeld M. Cell Metab. 2023 Feb 7. PMID: 36754020.
When aging gets on the way of disposal: Senescent cell suppression of efferocytosis.Rothlin CV, Ghosh S. J Cell Biol. 2023 Feb 6; 2023 Jan 5. PMID: 36602762.
Distinct Mechanisms of Mismatch-Repair Deficiency Delineate Two Modes of Response to Anti-PD-1 Immunotherapy in Endometrial Carcinoma.Chow RD, Michaels T, Bellone S, Hartwich TMP, Bonazzoli E, Iwasaki A, Song E, Santin AD. Cancer Discov. 2023 Feb 6. PMID: 36301137.
Validation of the Prognostic Usefulness of the Gene Expression Profiling Test in Patients with Uveal Melanoma.Miguez S, Lee RY, Chan AX, Demkowicz PC, Jones BSCL, Long CP, Abramson DH, Bosenberg M, Sznol M, Kluger H, Goldbaum MH, Francis JH, Pointdujour-Lim R, Bakhoum MF. Ophthalmology. 2023 Feb 4; 2023 Feb 4. PMID: 36739981.
Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes.Ren X, Wang D, Zhang G, Zhou T, Wei Z, Yang Y, Zheng Y, Lei X, Tao W, Wang A, Li M, Flavell RA, Zhu S. Sci Adv. 2023 Feb 3; 2023 Feb 3. PMID: 36735791.
Allobaculum mucilyticum sp. nov. and Allobaculum fili sp. nov., isolated from the human intestinal tract.van Muijlwijk GH, Rice TA, Flavell RA, Palm NW, de Zoete MR. Int J Syst Evol Microbiol. 2023 Feb. PMID: 36748696.
Platelet response to influenza vaccination reflects effects of aging.Konstorum A, Mohanty S, Zhao Y, Melillo A, Vander Wyk B, Nelson A, Tsang S, Blevins TP, Belshe RB, Chawla DG, Rondina MT, Gill TM, Montgomery RR, Allore HG, Kleinstein SH, Shaw AC. Aging Cell. 2023 Feb; 2023 Jan 19. PMID: 36656789.
Correction to: Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome.Fan W, Par-Young J, Li K, Zhang Y, Xiao P, Hua L, Leng L, Chen X, Bucala R. Clin Rheumatol. 2023 Feb. PMID: 36565380.
Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis.Nechanitzky R, Nechanitzky D, Ramachandran P, Duncan GS, Zheng C, Göbl C, Gill KT, Haight J, Wakeham AC, Snow BE, Bradaschia-Correa V, Ganguly M, Lu Z, Saunders ME, Flavell RA, Mak TW. Cell Death Differ. 2023 Feb; 2022 Dec 17. PMID: 36528755.
Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome.Fan W, Par-Young J, Li K, Zhang Y, Xiao P, Hua L, Leng L, Chen X, Bucala R. Clin Rheumatol. 2023 Feb; 2022 Nov 19. PMID: 36401063.
PD-1(high)CXCR5(-)CD4(+) peripheral helper T cells promote CXCR3(+) plasmablasts in human acute viral infection.Asashima H, Mohanty S, Comi M, Ruff WE, Hoehn KB, Wong P, Klein J, Lucas C, Cohen I, Coffey S, Lele N, Greta L, Raddassi K, Chaudhary O, Unterman A, Emu B, Kleinstein SH, Montgomery RR, Iwasaki A, Dela Cruz CS, Kaminski N, Shaw AC, Hafler DA, Sumida TS. Cell Rep. 2023 Jan 31; 2023 Jan 2. PMID: 36596303.
Cross talk on "endogenous SOD2 (superoxide dismutase) regulates platelet-dependent thrombin generation and thrombosis during aging" SOD2 in platelets: with age comes responsibility.Jain K, Gu SX, Hwa J. J Thromb Haemost. 2023 Jan 27; 2023 Jan 27. PMID: 36716965.
Inflammation of the retinal pigment epithelium drives early-onset photoreceptor degeneration in Mertk-associated retinitis pigmentosa.Mercau ME, Akalu YT, Mazzoni F, Gyimesi G, Alberto EJ, Kong Y, Hafler BP, Finnemann SC, Rothlin CV, Ghosh S. Sci Adv. 2023 Jan 20; 2023 Jan 20. PMID: 36662852.
Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD.Chen Y, Prévost J, Ullah I, Romero H, Lisi V, Tolbert WD, Grover JR, Ding S, Gong SY, Beaudoin-Bussières G, Gasser R, Benlarbi M, Vézina D, Anand SP, Chatterjee D, Goyette G, Grunst MW, Yang Z, Bo Y, Zhou F, Béland K, Bai X, Zeher AR, Huang RK, Nguyen DN, Sherburn R, Wu D, Piszczek G, Paré B, Matthies D, Xia D, Richard J, Kumar P, Mothes W, Côté M, Uchil PD, Lavallée VP, Smith MA, Pazgier M, Haddad E, Finzi A. iScience. 2023 Jan 20; 2022 Dec 9. PMID: 36514310.
Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity.Shinoda K, Li R, Rezk A, Mexhitaj I, Patterson KR, Kakara M, Zuroff L, Bennett JL, von Büdingen HC, Carruthers R, Edwards KR, Fallis R, Giacomini PS, Greenberg BM, Hafler DA, Ionete C, Kaunzner UW, Lock CB, Longbrake EE, Pardo G, Piehl F, Weber MS, Ziemssen T, Jacobs D, Gelfand JM, Cross AH, Cameron B, Musch B, Winger RC, Jia X, Harp CT, Herman A, Bar-Or A. Proc Natl Acad Sci U S A. 2023 Jan 17; 2023 Jan 12. PMID: 36634138.
The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice.Ullah I, Beaudoin-Bussières G, Symmes K, Cloutier M, Ducas E, Tauzin A, Laumaea A, Grunst MW, Dionne K, Richard J, Bégin P, Mothes W, Kumar P, Bazin R, Finzi A, Uchil PD. Cell Rep Med. 2023 Jan 17; 2022 Dec 29. PMID: 36584683.
Proteasome Inhibitors Interact Synergistically with BCL2, Histone Deacetylase, BET, and Jak Inhibitors against Cutaneous T-Cell Lymphoma Cells.Xu S, Ren J, Lewis JM, Carlson KR, Girardi M. J Invest Dermatol. 2023 Jan 13; 2023 Jan 13. PMID: 36642402.
Dynamics of the gut microbiome, IgA response, and plasma metabolome in the development of pediatric celiac disease.Girdhar K, Dogru YD, Huang Q, Yang Y, Tolstikov V, Raisingani A, Chrudinova M, Oh J, Kelley K, Ludvigsson JF, Kiebish MA, Palm NW, Ludvigsson J, Altindis E. Microbiome. 2023 Jan 13; 2023 Jan 13. PMID: 36639805.
T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.Briukhovetska D, Suarez-Gosalvez J, Voigt C, Markota A, Giannou AD, Schübel M, Jobst J, Zhang T, Dörr J, Märkl F, Majed L, Müller PJ, May P, Gottschlich A, Tokarew N, Lücke J, Oner A, Schwerdtfeger M, Andreu-Sanz D, Grünmeier R, Seifert M, Michaelides S, Hristov M, König LM, Cadilha BL, Mikhaylov O, Anders HJ, Rothenfusser S, Flavell RA, Cerezo-Wallis D, Tejedo C, Soengas MS, Bald T, Huber S, Endres S, Kobold S. Immunity. 2023 Jan 10. PMID: 36630913.
Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22.Giannou AD, Kempski J, Shiri AM, Lücke J, Zhang T, Zhao L, Zazara DE, Cortesi F, Riecken K, Amezcua Vesely MC, Low JS, Xu H, Kaffe E, Garcia-Perez L, Agalioti T, Yamada Y, Jungraithmayr W, Zigmond E, Karstens KF, Steglich B, Wagner J, Konczalla L, Carambia A, Schulze K, von Felden J, May P, Briukhovetska D, Bedke T, Brockmann L, Starzonek S, Lange T, Koch C, Riethdorf S, Pelczar P, Böttcher M, Sabihi M, Huber FJ, Reeh M, Grass JK, Wahib R, Seese H, Stüben BO, Fard-Aghaie M, Duprée A, Scognamiglio P, Plitzko G, Meiners J, Soukou S, Wittek A, Manthey C, Maroulis IC, Arck PC, Perez D, Gao B, Zarogiannis SG, Strowig T, Pasqualini R, Arap W, Gosálvez JS, Kobold S, Prinz I, Guse AH, Tachezy M, Ghadban T, Heumann A, Li J, Melling N, Mann O, Izbicki JR, Pantel K, Schumacher U, Lohse AW, Flavell RA, Gagliani N, Huber S. Immunity. 2023 Jan 10. PMID: 36630911.
Multicytokine-producing CD4+ T cells characterize the livers of patients with NASH.Woestemeier A, Scognamiglio P, Zhao Y, Wagner J, Muscate F, Casar C, Siracusa F, Cortesi F, Agalioti T, Müller S, Sagebiel A, Konczalla L, Wahib R, Karstens KF, Giannou AD, Duprée A, Wolter S, Wong MN, Mühlig AK, Bielecka AA, Bansal V, Zhang T, Mann O, Puelles VG, Huber TB, Lohse AW, Izbicki JR, Palm NW, Bonn S, Huber S, Gagliani N. JCI Insight. 2023 Jan 10; 2023 Jan 10. PMID: 36625344.
Interaction of glioma-associated microglia/macrophages and anti-PD1 immunotherapy.Wang C, Chen Q, Chen M, Guo S, Hou P, Zou Y, Wang J, He B, Zhang Q, Chen L, Luo L. Cancer Immunol Immunother. 2023 Jan 9; 2023 Jan 9. PMID: 36624155.
An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis.Wang S, Li K, Pickholz E, Dobie R, Matchett KP, Henderson NC, Carrico C, Driver I, Borch Jensen M, Chen L, Petitjean M, Bhattacharya D, Fiel MI, Liu X, Kisseleva T, Alon U, Adler M, Medzhitov R, Friedman SL. Sci Transl Med. 2023 Jan 4; 2023 Jan 4. PMID: 36599008.
SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to down-regulate MHC-I surface expression.Arshad N, Laurent-Rolle M, Ahmed WS, Hsu JC, Mitchell SM, Pawlak J, Sengupta D, Biswas KH, Cresswell P. Proc Natl Acad Sci U S A. 2023 Jan 3; 2022 Dec 27. PMID: 36574644.
Clonal lineage tracing reveals mechanisms skewing CD8+ T cell fate decisions in chronic infection.Kasmani MY, Zander R, Chung HK, Chen Y, Khatun A, Damo M, Topchyan P, Johnson KE, Levashova D, Burns R, Lorenz UM, Tarakanova VL, Joshi NS, Kaech SM, Cui W. J Exp Med. 2023 Jan 2; 2022 Oct 31. PMID: 36315049.
Platelet-derived TLT-1 promotes tumor progression by suppressing CD8+ T cells.Tyagi T, Jain K, Yarovinsky TO, Chiorazzi M, Du J, Castro C, Griffin J, Korde A, Martin KA, Takyar SS, Flavell RA, Patel AA, Hwa J. J Exp Med. 2023 Jan 2; 2022 Oct 28. PMID: 36305874.
The age of bone marrow dictates the clonality of smooth muscle-derived cells in atherosclerotic plaques.Kabir I, Zhang X, Dave JM, Chakraborty R, Qu R, Chandran RR, Ntokou A, Gallardo-Vara E, Aryal B, Rotllan N, Garcia-Milian R, Hwa J, Kluger Y, Martin KA, Fernández-Hernando C, Greif DM. Nat Aging. 2023 Jan; 2023 Jan 9. PMID: 36743663.
3D bioprinting of an implantable xeno-free vascularized human skin graft.Baltazar T, Jiang B, Moncayo A, Merola J, Albanna MZ, Saltzman WM, Pober JS. Bioeng Transl Med. 2023 Jan; 2022 Apr 21. PMID: 36684084.
Teaching an old dog new tricks: re-engineering IL-2 for immuno-oncology applications.Sznol M, Rizvi N. J Immunother Cancer. 2023 Jan. PMID: 36609489.
Reflections for the 50th Anniversary of The Journal of Rheumatology: The Past, Present, and Future of Rheumatology.Masi AT, Bucala RJ. J Rheumatol. 2023 Jan. PMID: 36587952.
Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children.Xu Q, Milanez-Almeida P, Martins AJ, Radtke AJ, Hoehn KB, Oguz C, Chen J, Liu C, Tang J, Grubbs G, Stein S, Ramelli S, Kabat J, Behzadpour H, Karkanitsa M, Spathies J, Kalish H, Kardava L, Kirby M, Cheung F, Preite S, Duncker PC, Kitakule MM, Romero N, Preciado D, Gitman L, Koroleva G, Smith G, Shaffer A, McBain IT, McGuire PJ, Pittaluga S, Germain RN, Apps R, Schwartz DM, Sadtler K, Moir S, Chertow DS, Kleinstein SH, Khurana S, Tsang JS, Mudd P, Schwartzberg PL, Manthiram K. Nat Immunol. 2023 Jan; 2022 Dec 19. PMID: 36536106.
A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes.Syed F, Singhal D, Raedschelders K, Krishnan P, Bone RN, McLaughlin MR, Van Eyk JE, Mirmira RG, Yang ML, Mamula MJ, Wu H, Liu X, Evans-Molina C. EBioMedicine. 2023 Jan; 2022 Dec 1. PMID: 36463755.
Real-Life Barriers to Diagnosis of Early Mycosis Fungoides: An International Expert Panel Discussion.Hodak E, Geskin L, Guenova E, Ortiz-Romero PL, Willemze R, Zheng J, Cowan R, Foss F, Mangas C, Querfeld C. Am J Clin Dermatol. 2023 Jan; 2022 Nov 18. PMID: 36399227.
The impact of the COVID-19 pandemic on eating disorders in U.S. military veterans.Mitchell KS, Smith BN, Masheb R, Vogt D. Int J Eat Disord. 2023 Jan; 2022 Oct 14. PMID: 36239518.
Autoantibody and T cell responses to oxidative post-translationally modified insulin neoantigenic peptides in type 1 diabetes.Strollo R, Vinci C, Man YKS, Bruzzaniti S, Piemonte E, Alhamar G, Briganti SI, Malandrucco I, Tramontana F, Fanali C, Garnett J, Buccafusca R, Guyer P, Mamula M, James EA, Pozzilli P, Ludvigsson J, Winyard PG, Galgani M, Nissim A. Diabetologia. 2023 Jan; 2022 Oct 7. PMID: 36207582.
Treatment at high-volume facilities is associated with improved overall survival for patients with cutaneous B-cell lymphoma.Cheraghlou S, Ugwu N, Girardi M. J Am Acad Dermatol. 2023 Jan; 2022 Apr 25. PMID: 35476920.

2022

Predictive accuracy of elevated mitotic rate on lymph node positivity and recurrence in thin melanomas.Ly CL, Blaha O, Wei W, Galan A, Kluger H, Ariyan S, Olino K, Clune JE. Front Oncol. 2022; 2023 Jan 6. PMID: 36686728.
Plasmodium infection is associated with cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein.Lapidus S, Liu F, Casanovas-Massana A, Dai Y, Huck JD, Lucas C, Klein J, Filler RB, Strine MS, Sy M, Deme AB, Badiane AS, Dieye B, Ndiaye IM, Diedhiou Y, Mbaye AM, Diagne CT, Vigan-Womas I, Mbengue A, Sadio BD, Diagne MM, Moore AJ, Mangou K, Diallo F, Sene SD, Pouye MN, Faye R, Diouf B, Nery N Jr, Costa F, Reis MG, Muenker MC, Hodson DZ, Mbarga Y, Katz BZ, Andrews JR, Campbell M, Srivathsan A, Kamath K, Baum-Jones E, Faye O, Sall AA, Vélez JCQ, Cappello M, Wilson M, Ben-Mamoun C, Tedder R, McClure M, Cherepanov P, Somé FA, Dabiré RK, Moukoko CEE, Ouédraogo JB, Boum Y 2nd, Shon J, Ndiaye D, Wisnewski A, Parikh S, Iwasaki A, Wilen CB, Ko AI, Ring AM, Bei AK. Sci Rep. 2022 Dec 22; 2022 Dec 22. PMID: 36550362.
Inguinal patch in mpox (monkeypox) virus infection and eccrine syringometaplasia: report of two cases with in situ hybridization and electron microscopy.Roy SF, Sarhan J, Liu X, Murphy MJ, Bunick CG, Choate KA, Damsky WB, McNiff JM. Br J Dermatol. 2022 Dec 21; 2022 Dec 21. PMID: 36763786.
Multi-objective optimization identifies a specific and interpretable COVID-19 host response signature.Cappuccio A, Chawla DG, Chen X, Rubenstein AB, Cheng WS, Mao W, Burke TW, Tsalik EL, Petzold E, Henao R, McClain MT, Woods CW, Chikina M, Troyanskaya OG, Sealfon SC, Kleinstein SH, Zaslavsky E. Cell Syst. 2022 Dec 21. PMID: 36549275.
Benchmarking transcriptional host response signatures for infection diagnosis.Chawla DG, Cappuccio A, Tamminga A, Sealfon SC, Zaslavsky E, Kleinstein SH. Cell Syst. 2022 Dec 21. PMID: 36549274.
Assembly and architecture of the type III secretion sorting platform.Soto JE, Galán JE, Lara-Tejero M. Proc Natl Acad Sci U S A. 2022 Dec 20; 2022 Dec 13. PMID: 36512499.
Epiregulin is a dendritic cell-derived EGFR ligand that maintains skin and lung fibrosis.Odell ID, Steach H, Gauld SB, Reinke-Breen L, Karman J, Carr TL, Wetter JB, Phillips L, Hinchcliff M, Flavell RA. Sci Immunol. 2022 Dec 16; 2022 Dec 9. PMID: 36490328.
Interferon opens up: HIV-induced inflammation reconfigures 3D chromatin conformation and affects where HIV integrates.Wei Y, Ho YC. Mol Cell. 2022 Dec 15. PMID: 36525953.
HIV is associated with poor overall survival among head and neck cancer patients.Salahuddin S, Cohen O, Wu M, Perez Irizarry J, Vega T, Gan G, Deng Y, Isaeva N, Prasad M, Schalper KA, Mehra S, Yarbrough WG, Emu B. Clin Infect Dis. 2022 Dec 15; 2022 Dec 15. PMID: 36520995.
A multiple sclerosis-protective coding variant reveals an essential role for HDAC7 in regulatory T cells.Axisa PP, Yoshida TM, Lucca LE, Kasler HG, Lincoln MR, Pham GH, Del Priore D, Carpier JM, Lucas CL, Verdin E, Sumida TS, Hafler DA. Sci Transl Med. 2022 Dec 14; 2022 Dec 14. PMID: 36516268.
Longitudinal single-cell analysis of a patient receiving adoptive cell therapy reveals potential mechanisms of treatment failure.Qu R, Kluger Y, Yang J, Zhao J, Hafler DA, Krause DS, Bersenev A, Bosenberg M, Hurwitz M, Lucca L, Kluger HM. Mol Cancer. 2022 Dec 14; 2022 Dec 14. PMID: 36514045.
Regulation of bone homeostasis by MERTK and TYRO3.Engelmann J, Zarrer J, Gensch V, Riecken K, Berenbrok N, Luu TV, Beitzen-Heineke A, Vargas-Delgado ME, Pantel K, Bokemeyer C, Bhamidipati S, Darwish IS, Masuda E, Burstyn-Cohen T, Alberto EJ, Ghosh S, Rothlin C, Hesse E, Taipaleenmäki H, Ben-Batalla I, Loges S. Nat Commun. 2022 Dec 12; 2022 Dec 12. PMID: 36509738.
Differential IL18 signaling via IL18 receptor and Na-Cl co-transporter discriminating thermogenesis and glucose metabolism regulation.Zhang X, Luo S, Wang M, Cao Q, Zhang Z, Huang Q, Li J, Deng Z, Liu T, Liu CL, Meppen M, Vromman A, Flavell RA, Hotamışlıgil GS, Liu J, Libby P, Liu Z, Shi GP. Nat Commun. 2022 Dec 8; 2022 Dec 8. PMID: 36482059.