Cancer Immunology Recent Publications

• Cholesterol promotes IFNG mRNA expression in CD4(+) effector/memory cells by SGK1 activation.Hanin A, Comi M, Sumida TS, Hafler DA. Life Sci Alliance. 2024 Dec; 2024 Oct 4. PMID: 39366761.
• Chart review study of real-world clinical outcomes in patients with cutaneous T-cell lymphoma treated with extracorporeal photopheresis in the US in 2017-2019.Girardi M, Carlson K, Huang X, Corman SL, Edmundson P, Schmier J, Kale HP, Raina R, Foss F. J Dermatolog Treat. 2024 Dec; 2024 Jun 9. PMID: 38852942.
• CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors.Skoulidis F, Araujo HA, Do MT, Qian Y, Sun X, Cobo AG, Le JT, Montesion M, Palmer R, Jahchan N, Juan JM, Min C, Yu Y, Pan X, Arbour KC, Vokes N, Schmidt ST, Molkentine D, Owen DH, Memmott R, Patil PD, Marmarelis ME, Awad MM, Murray JC, Hellyer JA, Gainor JF, Dimou A, Bestvina CM, Shu CA, Riess JW, Blakely CM, Pecot CV, Mezquita L, Tabbó F, Scheffler M, Digumarthy S, Mooradian MJ, Sacher AG, Lau SCM, Saltos AN, Rotow J, Johnson RP, Liu C, Stewart T, Goldberg SB, Killam J, Walther Z, Schalper K, Davies KD, Woodcock MG, Anagnostou V, Marrone KA, Forde PM, Ricciuti B, Venkatraman D, Van Allen EM, Cummings AL, Goldman JW, Shaish H, Kier M, Katz S, Aggarwal C, Ni Y, Azok JT, Segal J, Ritterhouse L, Neal JW, Lacroix L, Elamin YY, Negrao MV, Le X, Lam VK, Lewis WE, Kemp HN, Carter B, Roth JA, Swisher S, Lee R, Zhou T, Poteete A, Kong Y, Takehara T, Paula AG, Parra Cuentas ER, Behrens C, Wistuba II, Zhang J, Blumenschein GR, Gay C, Byers LA, Gibbons DL, Tsao A, Lee JJ, Bivona TG, Camidge DR, Gray JE, Lieghl N, Levy B, Brahmer JR, Garassino MC, Gandara DR, Garon EB, Rizvi NA, Scagliotti GV, Wolf J, Planchard D, Besse B, Herbst RS, Wakelee HA, Pennell NA, Shaw AT, Jänne PA, Carbone DP, Hellmann MD, Rudin CM, Albacker L, Mann H, Zhu Z, Lai Z, Stewart R, Peters S, Johnson ML, Wong KK, Huang A, Winslow MM, Rosen MJ, Winters IP, Papadimitrakopoulou VA, Cascone T, Jewsbury P, Heymach JV. Nature. 2024 Oct 9; 2024 Oct 9. PMID: 39385035.
• New potential ligand-receptor axis involved in tissue repair as therapeutic targets in progressive multiple sclerosis.Carrera Silva EA, Correale J, Rothlin C, Ortiz Wilczyñski JM. J Pharmacol Exp Ther. 2024 Oct 8; 2024 Oct 8. PMID: 39379148.
• Sensing DNA as danger: The discovery of cGAS.Flavell RA, Sefik E. Immunity. 2024 Oct 8; 2024 Sep 19. PMID: 39303723.
• CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies.Richard J, Sannier G, Zhu L, Prévost J, Marchitto L, Benlarbi M, Beaudoin-Bussières G, Kim H, Sun Y, Chatterjee D, Medjahed H, Bourassa C, Delgado G-G, Dubé M, Kirchhoff F, Hahn BH, Kumar P, Kaufmann DE, Finzi A. mBio. 2024 Oct 7; 2024 Oct 7. PMID: 39373535.
• Immune Cell Dynamics in EGFR-Mutated NSCLC Treated With Afatinib and Pembrolizumab: Results From a Phase IB Study.Riess JW, Lara MS, Lopez de Rodas M, Luxardi G, Herbert S, Shimoda M, Kelly K, Meerlev A, Moore E, Beckett L, Monjazeb A, Schalper K, Maverakis E, Gandara DR. JTO Clin Res Rep. 2024 Oct; 2024 Jul 14. PMID: 39318388.
• Percent Final Height Is a Novel Method That Identifies Differences Between the Rate of Development in American Children of Different Races.Taylor TN, Yang AA, Lee TM, Diejomaoh RM, Bridges CS, Kan JH, Smith BG, Cooperman DR. J Pediatr Orthop. 2024 Oct 1; 2024 Jun 28. PMID: 38938106.
• Evaluation of Benzene Presence and Formation in Benzoyl Peroxide Drug Products.Kucera K, Zenzola N, Hudspeth A, Dubnicka M, Hinz W, Bunick CG, Girardi M, Dabestani A, Light DY. J Invest Dermatol. 2024 Sep 27; 2024 Sep 27. PMID: 39384016.
• Feeding the wrath with myelin.Ghosh S, Rothlin CV. Trends Immunol. 2024 Sep 27; 2024 Sep 27. PMID: 39341708.
• Interpersonal emotion regulation and depressive symptoms in parent-adolescent dyads: A daily-diary investigation.Gadassi-Polack R, Questel M, Sened H, Marshall HE, Chen GJ, Geiger EJ, Bar Yosef T, Joormann J. Emotion. 2024 Sep 26; 2024 Sep 26. PMID: 39325395.
• National Patterns of Hospital Admission Versus Home Recovery Following Mastectomy for Breast Cancer.Kim LS, Moore MS, Schneider E, Canner J, Ayyala H, Chen J, Anant P, Graetz E, Lynch MA, Zanieski G, Gillego A, Valero MG, Proussaloglou EM, Berger ER, Golshan M, Greenup RA, Park TS. Ann Surg Oncol. 2024 Sep 25; 2024 Sep 25. PMID: 39322830.
• Contemporary Approach to The Diagnosis and Classification of Myelodysplastic Neoplasms/Syndromes- Recommendations from The International Consortium for MDS (icMDS).Aakash F, Gisriel SD, Zeidan AM, Bennett JM, Bejar R, Bewersdorf JP, Borate UM, Boultwood J, Brunner AM, Buckstein R, Carraway H, Churpek JE, Daver NG, DeZern AE, Efficace F, Fenaux P, Figueroa ME, Garcia-Manero G, Gore SD, Greenberg PL, Griffiths EA, Halene S, Hourigan CS, Kim TK, Kim N, Komrokji RS, Kutchroo V, List AF, Little RF, Majeti R, Nazha A, Nimer SD, Odenike O, Padron E, Patnaik MM, Platzbecker U, Della Porta MG, Roboz GJ, Sallman DA, Santini V, Sanz G, Savona MR, Sekeres MA, Stahl M, Starczynowski DT, Steensma DP, Taylor J, Abdel-Wahab O, Wei AH, Zhuoer X, Xu ML, Hasserjian RP, Loghavi S. Mod Pathol. 2024 Sep 23; 2024 Sep 23. PMID: 39322118.
• IL-1β Induces Human Endothelial Surface Expression of IL-15 by Relieving let-7c-3p Suppression of Protein Translation.Mullan CW, Summer L, Lopez-Giraldez F, Tobiasova Z, Manes TD, Yasothan S, Song G, Jane-Wit D, Saltzman WM, Pober JS. J Immunol. 2024 Sep 20; 2024 Sep 20. PMID: 39302113.
• Randomized Phase III SIERRA Trial of (131)I-Apamistamab Before Allogeneic Hematopoietic Cell Transplantation Versus Conventional Care for Relapsed/Refractory AML.Gyurkocza B, Nath R, Seropian S, Choe H, Litzow MR, Abboud C, Koshy N, Stiff P, Tomlinson B, Abhyankar S, Foran J, Hari P, Chen G, Al-Kadhimi Z, Kebriaei P, Sabloff M, Orozco JJ, Jamieson K, Silverman M, Van Besien K, Schuster M, Law AD, Larkin K, Pandit-Taskar N, Rowley SD, Munshi P, Cook R, Levy MY, Lazarus HM, Sandmaier BM, Pagel JM, Reddy V, MacDougall J, McNamara K, Spross J, Haeuber E, Vusirikala M, Nahar A, Desai A, Giralt S. J Clin Oncol. 2024 Sep 19; 2024 Sep 19. PMID: 39298738.
• Hyperedge Representations with Hypergraph Wavelets: Applications to Spatial Transcriptomics.Sun X, Xu C, Rocha JF, Liu C, Hollander-Bodie B, Goldman L, DiStasio M, Perlmutter M, Krishnaswamy S. ArXiv. 2024 Sep 14; 2024 Sep 14. PMID: 39314512.
• The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity.Guha A, Si Y, Smith R, Kazamel M, Jiang N, Smith KA, Thalacker-Mercer A, Singh BK, Ho R, Andrabi SA, Pereira JDTDS, Salgado JS, Agrawal M, Velic EH, King PH. bioRxiv. 2024 Sep 14; 2024 Sep 14. PMID: 39314333.
• Phenotypic and genotypic evaluation of bleeding diagnostic dilemmas: Two case studies.Gu SX, Butt A, Schulz VP, Rinder HM, Lee AI, Gallagher PG, Hwa J, Bona RD. Blood Cells Mol Dis. 2024 Sep 10; 2024 Sep 10. PMID: 39260211.
• Phase 2 trial of the farnesyltransferase inhibitor tipifarnib for relapsed/refractory peripheral T-cell lymphoma.Witzig T, Sokol L, Kim WS, de la Cruz Vicente F, Martín García-Sancho A, Advani R, Roncero Vidal JM, de Oña Navarrete R, Marín-Niebla A, Rodriguez Izquierdo A, Terol MJ, Domingo-Domenech E, Saunders A, Bendris N, Mackey J, Leoni M, Foss F. Blood Adv. 2024 Sep 10. PMID: 38991123.
• A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance.Mertens RT, Misra A, Xiao P, Baek S, Rone JM, Mangani D, Sivanathan KN, Arojojoye AS, Awuah SG, Lee I, Shi GP, Petrova B, Brook JR, Anderson AC, Flavell RA, Kanarek N, Hemberg M, Nowarski R. Immunity. 2024 Sep 10; 2024 Jun 20. PMID: 38906145.
• Vγ6/Vδ1+ γδ T cells protect from angiotensin II effects on blood pressure and endothelial function in mice.Mahmoud AUM, Caillon A, Shokoples B, Ferreira NS, Comeau K, Hatano S, Yoshikai Y, Lewis JM, Tigelaar RE, Paradis P, Schiffrin EL. J Hypertens. 2024 Sep 9; 2024 Sep 9. PMID: 39248136.
• Real World Data on Efficacy and Safety of EPOCH in T-Cell Lymphoma.Straining R, Foss F, Schiffer M, Amin K, Agarwal S, Isufi I, Huntington S, Kothari S, Seropian S, Girardi M, Sethi T. Clin Lymphoma Myeloma Leuk. 2024 Sep 8; 2024 Sep 8. PMID: 39368885.
• Putting computational models of immunity to the test - an invited challenge to predict B. pertussis vaccination outcomes.Shinde P, Willemsen L, Anderson M, Aoki M, Basu S, Burel JG, Cheng P, Dastidar SG, Dunleavy A, Einav T, Forschmiedt J, Fourati S, Garcia J, Gibson W, Greenbaum JA, Guan L, Guan W, Gygi JP, Ha B, Hou J, Hsiao J, Huang Y, Jansen R, Kakoty B, Kang Z, Kobie JJ, Kojima M, Konstorum A, Lee J, Lewis SA, Li A, Lock EF, Mahita J, Mendes M, Meng H, Neher A, Nili S, Olsen LR, Orfield S, Overton JA, Pai N, Parker C, Qian B, Rasmussen M, Reyna J, Richardson E, Safo S, Sorenson J, Srinivasan A, Thrupp N, Tippalagama R, Trevizani R, Ventz S, Wang J, Wu CC, Ay F, Grant B, Kleinstein SH, Peters B. bioRxiv. 2024 Sep 8; 2024 Sep 8. PMID: 39282381.
• Incidence of Pathologic Nodal Disease in Clinically Node-Negative, Microinvasive or T1a Breast Cancers.Dey P, Kc M, Proussaloglou EM, Khubchandani JA, Kim L, Zanieski G, Park T, Lynch M, Gillego A, Valero M, Schneider E, Golshan M, Greenup RA, Berger ER. Ann Surg Oncol. 2024 Sep 6; 2024 Sep 6. PMID: 39240394.
• Clinical and Histologic Variants of CD8+ Cutaneous T-Cell Lymphomas.Swallow MA, Micevic G, Zhou A, Carlson KR, Foss FM, Girardi M. Cancers (Basel). 2024 Sep 5; 2024 Sep 5. PMID: 39272944.
• Beta Spike-Presenting SARS-CoV-2 Virus-like Particle Vaccine Confers Broad Protection against Other VOCs in Mice.Ullah I, Symmes K, Keita K, Zhu L, Grunst MW, Li W, Mothes W, Kumar P, Uchil PD. Vaccines (Basel). 2024 Sep 2; 2024 Sep 2. PMID: 39340037.
• Endothelial γ-protocadherins inhibit KLF2 and KLF4 to promote atherosclerosis.Joshi D, Coon BG, Chakraborty R, Deng H, Yang Z, Babar MU, Fernandez-Tussy P, Meredith E, Attanasio J, Joshi N, Traylor JG Jr, Orr AW, Fernandez-Hernando C, Libreros S, Schwartz MA. Nat Cardiovasc Res. 2024 Sep; 2024 Sep 4. PMID: 39232138.
• ASTCT and USCLC Clinical Practice Recommendations for Allogeneic Stem Cell Transplant in Mycosis Fungoides and Sézary Syndrome.Goyal A, O'Leary D, Dabaja B, Weng WK, Zain J, Cutler C, Guitart J, Kim YH, Geskin LJ, Hoppe RT, Wilson LD, Beaven AW, Horwitz S, Allen PB, Barta SK, Bohjanen K, Brammer JE, Carter JB, Comfere N, DeSimone JA, Dusenbery K, Duvic M, Huen A, Jagadeesh D, Kelsey CR, Khodadoust MS, Lechowicz MJ, Mehta-Shah N, Moskowitz AJ, Olsen EA, Poh C, Pro B, Querfeld C, Sauter C, Sokol L, Sokumbi O, Wilcox RA, Zic JA, Hamadani M, Foss F. Transplant Cell Ther. 2024 Sep 1; 2024 Sep 1. PMID: 39222792.
• Understanding emerging and re-emerging viruses to facilitate pandemic preparedness.Zapatero-Belinchón FJ, Kumar P, Ott M, Schwartz O, Sigal A. Nat Microbiol. 2024 Sep. PMID: 39198691.
• Stem cells tightly regulate dead cell clearance to maintain tissue fitness.Stewart KS, Abdusselamoglu MD, Tierney MT, Gola A, Hur YH, Gonzales KAU, Yuan S, Bonny AR, Yang Y, Infarinato NR, Cowley CJ, Levorse JM, Pasolli HA, Ghosh S, Rothlin CV, Fuchs E. Nature. 2024 Sep; 2024 Aug 21. PMID: 39169186.
• Ultra-sensitive molecular residual disease detection through whole genome sequencing with single-read error correction.Li X, Liu T, Bacchiocchi A, Li M, Cheng W, Wittkop T, Mendez FL, Wang Y, Tang P, Yao Q, Bosenberg MW, Sznol M, Yan Q, Faham M, Weng L, Halaban R, Jin H, Hu Z. EMBO Mol Med. 2024 Sep; 2024 Aug 20. PMID: 39164471.
• Quantitative Measurement of HER2 Expression in Non-Small Cell Lung Cancer With a High-Sensitivity Assay.Liu M, Vathiotis I, Robbins CJ, Chan NNN, Moutafi M, Burela S, Xirou V, Schalper KA, Herbst RS, Syrigos K, Rimm DL. Mod Pathol. 2024 Sep; 2024 Jul 2. PMID: 38964502.
• A unified metric of human immune health.Sparks R, Rachmaninoff N, Lau WW, Hirsch DC, Bansal N, Martins AJ, Chen J, Liu CC, Cheung F, Failla LE, Biancotto A, Fantoni G, Sellers BA, Chawla DG, Howe KN, Mostaghimi D, Farmer R, Kotliarov Y, Calvo KR, Palmer C, Daub J, Foruraghi L, Kreuzburg S, Treat JD, Urban AK, Jones A, Romeo T, Deuitch NT, Moura NS, Weinstein B, Moir S, Ferrucci L, Barron KS, Aksentijevich I, Kleinstein SH, Townsley DM, Young NS, Frischmeyer-Guerrerio PA, Uzel G, Pinto-Patarroyo GP, Cudrici CD, Hoffmann P, Stone DL, Ombrello AK, Freeman AF, Zerbe CS, Kastner DL, Holland SM, Tsang JS. Nat Med. 2024 Sep; 2024 Jul 3. PMID: 38961223.
• Factors Associated with Long COVID Recovery among US Adults.Shah KM, Shah RM, Sawano M, Wu Y, Bishop P, Iwasaki A, Krumholz HM. Am J Med. 2024 Sep; 2024 Apr 21. PMID: 38649004.
• Prominent role of gut dysbiosis in the pathogenesis of cystic fibrosis-related liver disease in mice.Bertolini A, Nguyen M, Zehra SA, Taleb SA, Bauer-Pisani T, Palm N, Strazzabosco M, Fiorotto R. J Hepatol. 2024 Sep; 2024 Mar 28. PMID: 38554847.
• BCAM (basal cell adhesion molecule) protein expression in different tumor populations.Burela S, He M, Trontzas IP, Gavrielatou N, Schalper KA, Langermann S, Flies DB, Rimm DL, Aung TN. Discov Oncol. 2024 Aug 29; 2024 Aug 29. PMID: 39207605.
• An autoimmune transcriptional circuit drives FOXP3(+) regulatory T cell dysfunction.Sumida TS, Lincoln MR, He L, Park Y, Ota M, Oguchi A, Son R, Yi A, Stillwell HA, Leissa GA, Fujio K, Murakawa Y, Kulminski AM, Epstein CB, Bernstein BE, Kellis M, Hafler DA. Sci Transl Med. 2024 Aug 28; 2024 Aug 28. PMID: 39196959.
• The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC.Richard J, Grunst MW, Niu L, Díaz-Salinas MA, Tolbert WD, Marchitto L, Zhou F, Bourassa C, Yang D, Chiu TJ, Chen HC, Benlarbi M, Gottumukkala S, Li W, Dionne K, Bélanger É, Chatterjee D, Medjahed H, Hendrickson WA, Sodroski J, Lang ZC, Morton AJ, Huang RK, Matthies D, Smith AB 3rd, Mothes W, Munro JB, Pazgier M, Finzi A. bioRxiv. 2024 Aug 27; 2024 Aug 27. PMID: 39253431.
• Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation.Zhang P, Gorman J, Tsybovsky Y, Lu M, Liu Q, Gopan V, Singh M, Lin Y, Miao H, Seo Y, Kwon A, Olia AS, Chuang GY, Geng H, Lai YT, Zhou T, Mascola JR, Mothes W, Kwong PD, Lusso P. Cell Rep. 2024 Aug 27; 2024 Jul 18. PMID: 39028623.
• Characterization and implementation of the MarathonRT template-switching reaction to expand the capabilities of RNA-Seq.Guo LT, Grinko A, Olson S, Leipold A, Graveley B, Saliba AE, Pyle AM. RNA. 2024 Aug 22; 2024 Aug 22. PMID: 39174298.
• High-Dimensional Single-Cell Mass Cytometry Demonstrates Differential Platelet Functional Phenotypes in Infants With Congenital Heart Disease.Gu SX, Marcus BS, Gu VW, Varghese AP, Hwa J, Faustino EVS. Arterioscler Thromb Vasc Biol. 2024 Aug 22; 2024 Aug 22. PMID: 39171400.
• Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance.Yu J, Yan Y, Li S, Xu Y, Parolia A, Rizvi S, Wang W, Zhai Y, Xiao R, Li X, Liao P, Zhou J, Okla K, Lin H, Lin X, Grove S, Wei S, Vatan L, Hu J, Szumilo J, Kotarski J, Freeman ZT, Skala S, Wicha M, Cho KR, Chinnaiyan AM, Schon S, Wen F, Kryczek I, Wang S, Chen L, Zou W. Cell. 2024 Aug 22; 2024 Jul 4. PMID: 38968937.
• Early thrombus formation is required for eccentric and heterogeneous neointimal hyperplasia under disturbed flow.Bai H, Li Z, Zhang W, Thaxton C, Ohashi Y, Gonzalez L, Kano M, Yatsula B, Hwa J, Dardik A. J Thromb Haemost. 2024 Aug 21; 2024 Aug 21. PMID: 39173878.
• Electron tomography visualization of HIV-1 virions trapped by fusion inhibitors to host cells in infected tissues.Ladinsky MS, Zhu L, Ullah I, Uchil PD, Kumar P, Kay MS, Bjorkman PJ. bioRxiv. 2024 Aug 19; 2024 Aug 19. PMID: 39229189.
• Structure and inhibition of SARS-CoV-2 spike refolding in membranes.Grunst MW, Qin Z, Dodero-Rojas E, Ding S, Prévost J, Chen Y, Hu Y, Pazgier M, Wu S, Xie X, Finzi A, Onuchic JN, Whitford PC, Mothes W, Li W. Science. 2024 Aug 16; 2024 Aug 15. PMID: 39146425.
• SRF SUMOylation modulates smooth muscle phenotypic switch and vascular remodeling.Xu Y, Zhang H, Chen Y, Pober JS, Zhou M, Zhou JH, Min W. Nat Commun. 2024 Aug 13; 2024 Aug 13. PMID: 39134547.
• The amalgam of naive CD4(+) T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response.Even Z, Meli AP, Tyagi A, Vidyarthi A, Briggs N, de Kouchkovsky DA, Kong Y, Wang Y, Waizman DA, Rice TA, De Kumar B, Wang X, Palm NW, Craft J, Basu MK, Ghosh S, Rothlin CV. Immunity. 2024 Aug 13; 2024 Aug 2. PMID: 39096910.
• Addressing platelet insecurity - A national call to action.Gehrie EA, Young PP, Basavaraju SV, Bracey AW, Cap AP, Culler L, Dunbar NM, Homer M, Isufi I, Macedo R, Petraszko T, Ramsey G, Tormey CA, Kaufman RM, Snyder EL. Transfusion. 2024 Aug 12; 2024 Aug 12. PMID: 39133194.
• Macrophage migration inhibitory factor as a therapeutic target in neuro-oncology: A review.Jarmula J, Lee J, Lauko A, Rajappa P, Grabowski MM, Dhawan A, Chen P, Bucala R, Vogelbaum MA, Lathia JD. Neurooncol Adv. 2024 Jan-Dec; 2024 Aug 10. PMID: 39233830.
• Antibody gene features associated with binding and functional activity in malaria vaccine-derived human mAbs.Coelho CH, Marquez S, Nguemwo Tentokam BC, Berhe AD, Miura K, Rao VN, Long CA, Doumbo OK, Sagara I, Healy S, Kleinstein SH, Duffy PE. NPJ Vaccines. 2024 Aug 10; 2024 Aug 10. PMID: 39127706.
• Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway.Dudkina N, Park HB, Song D, Jain A, Khan SA, Flavell RA, Johnson CH, Palm NW, Crawford JM. Cell Chem Biol. 2024 Aug 9; 2024 Aug 9. PMID: 39163853.
• The human CD47 checkpoint is targeted by an immunosuppressive Aedes aegypti salivary factor to enhance arboviral skin infectivity.Marin-Lopez A, Huck JD, Esterly AT, Azcutia V, Rosen C, Garcia-Milian R, Sefik E, Vidal-Pedrola G, Raduwan H, Chen TY, Arora G, Halene S, Shaw AC, Palm NW, Flavell RA, Parkos CA, Thangamani S, Ring AM, Fikrig E. Sci Immunol. 2024 Aug 9; 2024 Aug 9. PMID: 39121194.
• Enhanced Intratumoral Delivery of Immunomodulator Monophosphoryl Lipid A through Hyperbranched Polyglycerol-Coated Biodegradable Nanoparticles.Chang J, Shin K, Lewis JM, Suh HW, Lee J, Damsky W, Xu S, Bosenberg M, Saltzman WM, Girardi M. J Invest Dermatol. 2024 Aug 8; 2024 Aug 8. PMID: 39122142.
• Nuclear-penetrating scleroderma autoantibody inhibits topoisomerase 1 cleavage complex formation.May CK, Noble PW, Herzog EL, Meffre E, Hansen JE. Biochem Biophys Res Commun. 2024 Aug 6; 2024 May 14. PMID: 38759301.
• The physical landscape of CAR-T synapse.Xiong Y, Libby KA, Su X. Biophys J. 2024 Aug 6; 2023 Sep 15. PMID: 37715447.
• Maturation of germinal center B cells after influenza virus vaccination in humans.McIntire KM, Meng H, Lin TH, Kim W, Moore NE, Han J, McMahon M, Wang M, Malladi SK, Mohammed BM, Zhou JQ, Schmitz AJ, Hoehn KB, Carreño JM, Yellin T, Suessen T, Middleton WD, Teefey SA, Presti RM, Krammer F, Turner JS, Ward AB, Wilson IA, Kleinstein SH, Ellebedy AH. J Exp Med. 2024 Aug 5; 2024 Jun 27. PMID: 38935072.
• Phase I studies of davoceticept (ALPN-202), a PD-L1-dependent CD28 co-stimulator and dual PD-L1/CTLA-4 inhibitor, as monotherapy and in combination with pembrolizumab in advanced solid tumors (NEON-1 and NEON-2).Davar D, Cavalcante L, Lakhani N, Moser J, Millward M, McKean M, Voskoboynik M, Sanborn RE, Grewal JS, Narayan A, Patnaik A, Gainor JF, Sznol M, Enstrom A, Blanchfield L, LeBlanc H, Thomas H, Chisamore MJ, Peng SL, Naumovski A. J Immunother Cancer. 2024 Aug 3; 2024 Aug 3. PMID: 39097413.
• Long COVID science, research and policy.Al-Aly Z, Davis H, McCorkell L, Soares L, Wulf-Hanson S, Iwasaki A, Topol EJ. Nat Med. 2024 Aug; 2024 Aug 9. PMID: 39122965.
• Investigating the Bone Bruise Patterns in Pediatric Patients With Contact and Noncontact Acute Anterior Cruciate Ligament Tears: A Multicenter Study.Moran J, Amaral JZ, Lee M, Jones RH, Gross P, Katz LD, Wang A, Carrino JA, Jimenez AE, Chhabra BN, Kan JH, Smith BG, Gladstein AZ, McKay SD, LaPrade RF, Fabricant PD, Medvecky MJ. Am J Sports Med. 2024 Aug; 2024 Aug 5. PMID: 39101652.
• SARS-CoV-2-related bat viruses evade human intrinsic immunity but lack efficient transmission capacity.Peña-Hernández MA, Alfajaro MM, Filler RB, Moriyama M, Keeler EL, Ranglin ZE, Kong Y, Mao T, Menasche BL, Mankowski MC, Zhao Z, Vogels CBF, Hahn AM, Kalinich CC, Zhang S, Huston N, Wan H, Araujo-Tavares R, Lindenbach BD, Homer R, Pyle AM, Martinez DR, Grubaugh ND, Israelow B, Iwasaki A, Wilen CB. Nat Microbiol. 2024 Aug; 2024 Jul 29. PMID: 39075235.
• UBXN3B is crucial for B lymphopoiesis.Geng T, Yang D, Lin T, Harrison AG, Wang B, Cao Z, Torrance B, Fan Z, Wang K, Wang Y, Yang L, Haynes L, Cheng G, Vella AT, Flavell RA, Pereira JP, Fikrig E, Wang P. EBioMedicine. 2024 Aug; 2024 Jul 16. PMID: 39018756.
• PI3Kγ in B cells promotes antibody responses and generation of antibody-secreting cells.Lanahan SM, Yang L, Jones KM, Qi Z, Cabrera EC, Cominsky LY, Ramaswamy A, Barmada A, Gabernet G, Uthaya Kumar DB, Xu L, Shan P, Wymann MP, Kleinstein SH, Rao VK, Mustillo P, Romberg N, Abraham RS, Lucas CL. Nat Immunol. 2024 Aug; 2024 Jul 3. PMID: 38961274.
• Adverse Food Reactions: Physiological and Ecological Perspectives.Korn LL, Kutyavin VI, Bachtel ND, Medzhitov R. Annu Rev Nutr. 2024 Aug; 2024 Aug 12. PMID: 38724028.
• Adenocarcinoma of anogenital mammary gland type arising from encapsulated papillary carcinoma: A rare vulvar tumor mimicking breast carcinoma.Tang H, Laskin WB, Luan Y, McNiff JM, Zhan H. J Cutan Pathol. 2024 Aug; 2024 May 6. PMID: 38711196.
• Cutaneous diatoms from diatomaceous earth mimicking myiasis infection.Roy SF, Micevic G, McNiff JM, Christensen SR, Cowper SE. Pathology. 2024 Aug; 2024 Feb 17. PMID: 38471986.
• Meta-analysis identifies common gut microbiota associated with multiple sclerosis.Lin Q, Dorsett Y, Mirza A, Tremlett H, Piccio L, Longbrake EE, Choileain SN, Hafler DA, Cox LM, Weiner HL, Yamamura T, Chen K, Wu Y, Zhou Y. Genome Med. 2024 Jul 31; 2024 Jul 31. PMID: 39085949.
• Causes of death and patterns of metastatic disease at the end of life for patients with advanced melanoma in the immunotherapy era.Lee DY, McNamara M, Yang A, Yaskolko M, Kluger H, Tran T, Olino K, Clune J, Sznol M, Ishizuka JJ. Pigment Cell Melanoma Res. 2024 Jul 28; 2024 Jul 28. PMID: 39073002.
• Internal Tremors and Vibrations in Long COVID: A Cross-Sectional Study.Zhou T, Sawano M, Arun AS, Caraballo C, Michelsen T, McAlpine LS, Bhattacharjee B, Lu Y, Khera R, Huang C, Warner F, Herrin J, Iwasaki A, Krumholz HM. Am J Med. 2024 Jul 26; 2024 Jul 26. PMID: 39069199.
• nf-core/airrflow: An adaptive immune receptor repertoire analysis workflow employing the Immcantation framework.Gabernet G, Marquez S, Bjornson R, Peltzer A, Meng H, Aron E, Lee NY, Jensen CG, Ladd D, Polster M, Hanssen F, Heumos S, Yaari G, Kowarik MC, Nahnsen S, Kleinstein SH. PLoS Comput Biol. 2024 Jul; 2024 Jul 26. PMID: 39058741.
• An atlas of human vector-borne microbe interactions reveals pathogenicity mechanisms.Hart TM, Sonnert ND, Tang X, Chaurasia R, Allen PE, Hunt JR, Read CB, Johnson EE, Arora G, Dai Y, Cui Y, Chuang YM, Yu Q, Rahman MS, Mendes MT, Rolandelli A, Singh P, Tripathi AK, Ben Mamoun C, Caimano MJ, Radolf JD, Lin YP, Fingerle V, Margos G, Pal U, Johnson RM, Pedra JHF, Azad AF, Salje J, Dimopoulos G, Vinetz JM, Carlyon JA, Palm NW, Fikrig E, Ring AM. Cell. 2024 Jul 25; 2024 Jun 13. PMID: 38876107.
• The Xenorhabdus nematophila LrhA transcriptional regulator modulates production of γ-keto-N-acyl amides with inhibitory activity against mutualistic host nematode egg hatching.Lam YC, Hamchand R, Mucci NC, Kauffman SJ, Dudkina N, Reagle EV, Casanova-Torres ÁM, DeCuyper J, Chen H, Song D, Thomas MG, Palm NW, Goodrich-Blair H, Crawford JM. Appl Environ Microbiol. 2024 Jul 24; 2024 Jun 25. PMID: 38916293.
• Single-cell analysis reveals transcriptional dynamics in healthy primary parathyroid tissue.Venkat A, Carlino MJ, Lawton BR, Prasad ML, Amodio M, Gibson CE, Zeiss CJ, Youlten SE, Krishnaswamy S, Krause DS. Genome Res. 2024 Jul 23; 2024 Jul 23. PMID: 38977309.
• Biomarker development for PD-(L)1 axis inhibition: a consensus view from the SITC Biomarkers Committee.Monette A, Warren S, Barrett JC, Garnett-Benson C, Schalper KA, Taube JM, Topp B, Snyder A. J Immunother Cancer. 2024 Jul 20; 2024 Jul 20. PMID: 39032943.
• Camptothecin-loaded mesoporous silica nanoparticles functionalized with CpG oligodeoxynucleotide as a new approach for skin cancer treatment.Qureshi M, Viegas C, Duarte SOD, Girardi M, Shehzad A, Fonte P. Int J Pharm. 2024 Jul 20; 2024 Jun 13. PMID: 38878838.
• Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma.Valdez CN, Sánchez-Zuno GA, Osmani L, Ibrahim W, Galan A, Bacchiocchi A, Halaban R, Kulkarni RP, Kang I, Bucala R, Tran T. Oncotarget. 2024 Jul 19; 2024 Jul 19. PMID: 39028303.
• Dissecting human monoclonal antibody responses from mRNA- and protein-based XBB.1.5 COVID-19 monovalent vaccines.Fantin RF, Clark JJ, Cohn H, Jaiswal D, Bozarth B, Civljak A, Rao V, Lobo I, Nardulli JR, Srivastava K, Yong J, Andreata-Santos R, Bushfield K, Lee ES, Singh G, Kleinstein SH, Krammer F, Simon V, Bajic G, Coelho CH. bioRxiv. 2024 Jul 16; 2024 Jul 16. PMID: 39071292.
• The West Nile virus genome harbors essential riboregulatory elements with conserved and host-specific functional roles.Huston NC, Tsao LH, Brackney DE, Pyle AM. Proc Natl Acad Sci U S A. 2024 Jul 16; 2024 Jul 10. PMID: 38985757.
• A crisis in clinical research.Hong DS, LoRusso P, Sznol M. J Immunother Cancer. 2024 Jul 11; 2024 Jul 11. PMID: 38991727.
• Western diet reduces small intestinal intraepithelial lymphocytes via FXR-Interferon pathway.Hung CT, Ma C, Panda SK, Trsan T, Hodel M, Frein J, Foster A, Sun S, Wu HT, Kern J, Mishra R, Jain U, Ho YC, Colonna M, Stappenbeck TS, Liu TC. Mucosal Immunol. 2024 Jul 9; 2024 Jul 9. PMID: 38992433.
• Downregulation of adipose LPL by PAR2 contributes to the development of hypertriglyceridemia.Huang Y, Chen L, Li L, Qi Y, Tong H, Wu H, Xu J, Leng L, Cheema S, Sun G, Xia Z, McGuire J, Rodrigues B, Young LH, Bucala R, Qi D. JCI Insight. 2024 Jul 8; 2024 Jul 8. PMID: 38973609.
• Methionine sulfoxide reductase B2 protects against cardiac complications in diabetes mellitus.Lee SH, Cho S, Lee JY, Kim JY, Kim S, Jeong M, Hong JY, Kim GY, Lee SW, Kim E, Kim J, Kim JW, Hwa J, Kim WH. Diabetol Metab Syndr. 2024 Jul 5; 2024 Jul 5. PMID: 38970135.
• Costs of care during chimeric antigen receptor T-cell therapy in relapsed or refractory B-cell lymphomas.Di M, Potnis KC, Long JB, Isufi I, Foss F, Seropian S, Gross CP, Huntington SF. JNCI Cancer Spectr. 2024 Jul 1. PMID: 39115391.
• Interleukin-7-based identification of liver lymphatic endothelial cells reveals their unique structural features.Yang Y, Jeong J, Su T, Lai S, Zhang P, Garcia-Milian R, Graham M, Liu X, McConnell MJ, Utsumi T, Pereira J, Iwakiri Y. JHEP Rep. 2024 Jul; 2024 Mar 18. PMID: 38966234.
• Novel strategies for targeting neutrophil against myocardial infarction.Jiang K, Hwa J, Xiang Y. Pharmacol Res. 2024 Jul; 2024 Jun 10. PMID: 38866263.
• A small-molecule allele-selective transcriptional inhibitor of the MIF immune susceptibility locus.Li J, Leng L, Pantouris G, Manjula R, Piecychna M, Abriola L, Hu B, Lolis E, Armstrong ME, Donnelly SC, Bucala R. J Biol Chem. 2024 Jul; 2024 Jun 3. PMID: 38838773.
• Single-Cell Transcriptomic Analyses of Brain Parenchyma in Patients With New-Onset Refractory Status Epilepticus (NORSE).Hanin A, Zhang L, Huttner AJ, Plu I, Mathon B, Bielle F, Navarro V, Hirsch LJ, Hafler DA. Neurol Neuroimmunol Neuroinflamm. 2024 Jul; 2024 May 29. PMID: 38810181.
• Tumor Necrosis Factor Receptor-2 Signals Clear-Cell Renal Carcinoma Proliferation via Phosphorylated 4E Binding Protein-1 and Mitochondrial Gene Translation.Al-Lamki RS, Tolkovsky AM, Alawwami M, Lu W, Field SF, Wang J, Pober JS, Bradley JR. Am J Pathol. 2024 Jul; 2024 Mar 25. PMID: 38537932.
• The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases.Sumida TS, Cheru NT, Hafler DA. Nat Rev Immunol. 2024 Jul; 2024 Feb 19. PMID: 38374298.
• Neutrophils insert elastase into hepatocytes to regulate calcium signaling in alcohol-associated hepatitis.Ogino N, Leite MF, Guerra MT, Kruglov E, Asashima H, Hafler DA, Ito T, Pereira JP, Peiffer BJ, Sun Z, Ehrlich BE, Nathanson MH. J Clin Invest. 2024 Jun 25; 2024 Jun 25. PMID: 38916955.
• A causal link between autoantibodies and neurological symptoms in long COVID.Santos Guedes de Sa K, Silva J, Bayarri-Olmos R, Brinda R, Alec Rath Constable R, Colom Diaz PA, Kwon DI, Rodrigues G, Wenxue L, Baker C, Bhattacharjee B, Wood J, Tabacof L, Liu Y, Putrino D, Horvath TL, Iwasaki A. medRxiv. 2024 Jun 19; 2024 Jun 19. PMID: 38947091.
• A dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models.Stabach PR, Sims D, Gomez-Bañuelos E, Zehentmeier S, Dammen-Brower K, Bernhisel A, Kujawski S, Lopez SG, Petri M, Goldman DW, Lester ER, Le Q, Ishaq T, Kim H, Srivastava S, Kumar D, Pereira JP, Yarema KJ, Koumpouras F, Andrade F, Braddock DT. JCI Insight. 2024 Jun 18; 2024 Jun 18. PMID: 38888971.
• Inflammatory Response and Defects on Myelin Integrity in the Olfactory System of K18hACE2 Mice Infected with SARS-CoV-2.Martin-Lopez E, Brennan B, Mao T, Spence N, Meller SJ, Han K, Yahiaoui N, Wang C, Iwasaki A, Greer CA. eNeuro. 2024 Jun; 2024 Jun 17. PMID: 38834299.
• The single-cell opioid responses in the context of HIV (SCORCH) consortium.Ament SA, Campbell RR, Lobo MK, Receveur JP, Agrawal K, Borjabad A, Byrareddy SN, Chang L, Clarke D, Emani P, Gabuzda D, Gaulton KJ, Giglio M, Giorgi FM, Gok B, Guda C, Hadas E, Herb BR, Hu W, Huttner A, Ishmam MR, Jacobs MM, Kelschenbach J, Kim DW, Lee C, Liu S, Liu X, Madras BK, Mahurkar AA, Mash DC, Mukamel EA, Niu M, O'Connor RM, Pagan CM, Pang APS, Pillai P, Repunte-Canonigo V, Ruzicka WB, Stanley J, Tickle T, Tsai SA, Wang A, Wills L, Wilson AM, Wright SN, Xu S, Yang J, Zand M, Zhang L, Zhang J, Akbarian S, Buch S, Cheng CS, Corley MJ, Fox HS, Gerstein M, Gummuluru S, Heiman M, Ho YC, Kellis M, Kenny PJ, Kluger Y, Milner TA, Moore DJ, Morgello S, Ndhlovu LC, Rana TM, Sanna PP, Satterlee JS, Sestan N, Spector SA, Spudich S, Tilgner HU, Volsky DJ, White OR, Williams DW, Zeng H. Mol Psychiatry. 2024 Jun 15; 2024 Jun 15. PMID: 38879719.
• Systemic Treatment with siRNA Targeting Gamma-Secretase Activating Protein Inhibits Amyloid-β Accumulation in Alzheimer's Disease.Kim S, Ullah I, Beloor J, Chung K, Kim J, Yi Y, Kang E, Yun G, Heo S, Pyun SH, Kim SH, Kumar P, Lee SK. Biomater Res. 2024; 2024 Jun 12. PMID: 38868092.
• nipalsMCIA: Flexible Multi-Block Dimensionality Reduction in R via Non-linear Iterative Partial Least Squares.Mattessich M, Reyna J, Aron E, Ay F, Kilmer M, Kleinstein SH, Konstorum A. bioRxiv. 2024 Jun 10; 2024 Jun 10. PMID: 38915554.
• High-throughput transcriptome profiling indicates ribosomal RNAs to be associated with resistance to immunotherapy in non-small cell lung cancer (NSCLC).Moutafi MK, Bates KM, Aung TN, Milian RG, Xirou V, Vathiotis IA, Gavrielatou N, Angelakis A, Schalper KA, Salichos L, Rimm DL. J Immunother Cancer. 2024 Jun 10; 2024 Jun 10. PMID: 38857914.
• Psychosocial burden of autoimmune blistering diseases: A comprehensive survey study.White MA, Hoffman VM, Yale M, Strong R, Tomayko MM. J Eur Acad Dermatol Venereol. 2024 Jun 4; 2024 Jun 4. PMID: 38837452.
• "Rounding Third Base and Heading Home": Arthritis & Rheumatology in 2024.Solomon DH, Kaplan MJ, Nigrovic PA, Bucala R. Arthritis Rheumatol. 2024 Jun; 2024 Apr 4. PMID: 38572586.
• Factors Associated With Long COVID: Insights From Two Nationwide Surveys.Wu Y, Sawano M, Wu Y, Shah RM, Bishop P, Iwasaki A, Krumholz HM. Am J Med. 2024 Jun; 2024 Mar 14. PMID: 38490304.
• Multicenter prospective blinded melanoma detection study with a handheld elastic scattering spectroscopy device.Hartman RI, Trepanowski N, Chang MS, Tepedino K, Gianacas C, McNiff JM, Fung M, Braghiroli NF, Grant-Kels JM. JAAD Int. 2024 Jun; 2023 Nov 15. PMID: 38371666.