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Yale Center for Immuno-Oncology

The Yale Center for Immuno-Oncology was established in 2018 to build on Yale Cancer Center’s international leadership in immunology, immunobiology, and the development of innovative cancer immunotherapies. The Center is a partnership between Yale Cancer Center and the Department of Immunobiology at Yale School of Medicine.

The goals for the Yale Center for Immuno-Oncology (YCIO) include to:
  • Leverage Yale leadership in immunobiology and immunotherapy drug development.
  • Develop the next generation of immune-based therapies.
  • Genetically engineer immune cells to target a patient’s cancer (cell therapies).

“This new center gives us the chance to work more collaboratively and efficiently with our world-renowned scientists and faculty to address scientific questions in Immuno-Oncology,” said Marcus Bosenberg, MD, PhD, Professor of Dermatology, Pathology, and Immunobiology, and director of YCIO.


  • Anthony N. Brady Professor of Dermatology, Pathology and Immunobiology; Director, Yale SPORE in Skin Cancer; Director, Yale Center for Immuno-Oncology; Co-Leader, Cancer Immunology, Yale Cancer Center


  • Anthony N. Brady Professor of Medicine (Medical Oncology); Chief Translational Research Officer, Yale Cancer Center; Chief, Head and Neck Cancers/Sarcoma; Co-Leader, Developmental Therapeutics, Yale Cancer Center; Associate Cancer Center Director for Translational Research, Yale Cancer Center

    Research Interests
    • Drug Therapy
    • Head and Neck Neoplasms
    • Medical Oncology
    • Chemicals and Drugs
    • Analytical, Diagnostic and Therapeutic Techniques and Equipment
  • Associate Professor of Radiology & Biomedical Imaging and of Pharmacology

    Research Interests
    • Alzheimer Disease
    • Chemistry, Pharmaceutical
    • Pharmacokinetics
    • Pharmacology
    • Biomarkers
    • Neurodegenerative Diseases
    • Positron-Emission Tomography
    • Drug Discovery
    • Drug Development
  • Assistant Professor

    Research Interests
    • Autoimmune Diseases
    • HLA Antigens
    • Immunotherapy
    • Major Histocompatibility Complex
    • Mass Spectrometry
    • Antigen Presentation
    • Computational Biology
    • Cancer Vaccines
    • Neurodegenerative Diseases
    • Proteomics
    • Microfluidics
    • Systems Biology
    • Infectious Disease Medicine
    • Single-Cell Analysis
    • Spatial Analysis
    • Space Research
  • Associate Professor of Genetics and of Neurosurgery

    Research Interests
    • Biomedical Engineering
    • Cell Transformation, Neoplastic
    • Genetics
    • Immunity
    • Immunotherapy
    • Lymphocytes
    • Neoplasm Metastasis
    • Stem Cells
    • Therapeutics
    • Immunotherapy, Adoptive
    • Genomics
    • Systems Biology
    • Metabolomics
    • Bioengineering
    • Synthetic Biology
    • CRISPR-Cas Systems
  • Paul B. Beeson Professor of Medicine (Rheumatology) and Professor of Immunobiology; Paul B. Beeson Professor of Medicine, Internal Medicine: Rheumatology; Program Director, Investigative Medicine, Internal Medicine: Rheumatology

    Research Interests
    • Antigens, Differentiation, T-Lymphocyte
    • Autoimmune Diseases
    • Biology
    • Immunity
    • Lupus Erythematosus, Systemic
    • Investigative Techniques
    • Rheumatology
    • Cytokines
  • Assistant Professor of Medicine (Hematology); Assistant Professor of Medicine (Hematology), Internal Medicine

    Research Interests
    • Anemia, Aplastic
    • Blood Transfusion
    • Bone Marrow Diseases
    • Immunotherapy
    • Leukemia
    • Lymphoma
    • Multiple Myeloma
    • Myelodysplastic Syndromes
    • Hematopoietic Stem Cell Transplantation
    • Primary Myelofibrosis
  • Ensign Professor of Medicine (Medical Oncology) and Professor of Pharmacology; Deputy Director, Yale Cancer Center; Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital; Assistant Dean for Translational Research, Yale School of Medicine; Director, Center for Thoracic Cancers, Yale Cancer Center and Smilow Cancer Hospital; Program Director, Master of Health Science - Clinical Investigation Track (MHS-CI)

    Research Interests
    • Lung Neoplasms
    • Medical Oncology
    • Thoracic Neoplasms
    • Clinical Trials, Phase I as Topic
    • Biomarkers, Pharmacological
    • Precision Medicine
  • Sterling Professor of Immunobiology and Professor of Dermatology and of Molecular, Cellular, and Developmental Biology and of Epidemiology (Microbial Diseases); Investigator, Howard Hughes Medical Institute

    Research Interests
    • Arboviruses
    • Autophagy
    • DNA Viruses
    • Herpes Simplex
    • Immune System
    • Immunity, Cellular
    • Immunity, Innate
    • Influenza, Human
    • Molecular Biology
    • Pneumonia, Viral
    • Pregnancy Complications
    • Proviruses
    • RNA Viruses
    • Sexually Transmitted Diseases
    • Tumor Virus Infections
    • Encephalitis, Viral
    • Central Nervous System Viral Diseases
    • Inflammasomes
  • Harvey and Kate Cushing Professor of Medicine (Oncology) and of Dermatology; Director, Yale SPORE in Skin Cancer, Yale Cancer Center; Vice Chair for Collaborative Research, Internal Medicine; Chief, Division of Skin and Kidney Cancer; Associate Cancer Center Director, Education, Training and Faculty Development; Deputy Section Chief, Medical Oncology

    Research Interests
    • Medical Oncology
    • Melanoma
  • Anthony N. Brady Professor of Laboratory Medicine and Professor of Pathology; Vice Chair for Research Affairs, Laboratory Medicine; Assoc. Director, Yale Stem Cell Center; Assoc. Director, Transfusion Medicine Service; Medical Director, Clinical Cell Processing Laboratory; Medical Director, Advanced Cell Therapy Laboratory

    Research Interests
    • Cell Biology
    • Hematology
    • Leukemia
    • Pathology
    • Stem Cells
    • Gene Expression
    • Bone Marrow Transplantation
  • Professor of Radiology & Biomedical Imaging and Medical and Surgical Oncology; Vice Chair for Clinical Research, Radiology & Biomedical Imaging; Section Chief, Interventional Radiology

    Research Interests
    • Biliary Tract Neoplasms
    • Carcinoma, Renal Cell
    • Carcinoma, Hepatocellular
    • Hypertension, Portal
    • Liver Cirrhosis
    • Liver Cirrhosis, Experimental
    • Liver Neoplasms
    • Neoplasm Metastasis
    • Colorectal Neoplasms
    • Clinical Trial, Phase I
    • Cholangiocarcinoma
    • Neuroendocrine Tumors
    • Regenerative Medicine
    • Small Cell Lung Carcinoma