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SPORE in Skin Cancer

The Yale SPORE in Skin Cancer is funded by a $12.5 million grant from the National Cancer Institute to improve prevention and therapies for patients with melanoma.

Melanoma is the skin cancer that most frequently metastasizes to other sites in the body.

The Specialized Program of Research Excellence (SPORE) in Skin Cancer grant supports multidisciplinary research that extends from the laboratory to the clinic and back. Harriet Kluger, MD and Marcus Bosenberg, MD, PhD, are Principal Investigators of the multi-faceted program.

The Yale SPORE includes studies of novel sunscreens to prevent skin cancer, methods to determine who will or will not respond to immune therapy, and projects focusing on overcoming resistance to currently approved immune therapies.

The program also includes career development opportunities to encourage new investigators to study melanoma and a series of pilot projects focused on skin cancer that will result in further expansion of melanoma research at Yale.

The SPORE includes investigators in Dermatology, Medical Oncology, Pathology, Genetics, Immunobiology, Laboratory Medicine, Pharmacology, Neurology, Biomedical Engineering, Epidemiology and Public Health and Surgery. The team has diverse basic science and clinical expertise, as well as expertise in bioinformatics, biostatistics, and artificial intelligence.