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Mary Barden, MD, participates in a Q&A in honor of Brain Tumor Awareness Month.

“We’re starting to understand more about the biology of SCLC. [Our] work over the years shows that there is heterogeneity, there are different ways to classify SCLC, and, more recently, this idea of transcriptomic or molecular subtypes [has emerged],” Anne Chiang, MD, PhD, associate professor of medicine and associate cancer center director, clinical initiatives, at Yale School of Medicine in New Haven, Connecticut, said in an interview with OncologyLive.

Latest results with ctDNA, single-cell RNA sequencing, and the microbiome.

The 48 Yale Cancer Center presentations will include phase II trial results for a cancer vaccine in combination with an immunotherapy drug, a new tool to predict the risk of recurrence of hormone receptor-positive, HER2-negative breast cancer, and the factors affecting sexual function of young women with breast cancer.

Roy S. Herbst, MD, PhD, deputy director and chief of medical oncology at Yale Cancer Center, New Haven, Connecticut, emphasized the need for further research to refine the utility of ctDNA analysis in guiding treatment decisions, especially in advanced disease. He expressed reservations about the use of chemotherapy in combination with targeted therapy, citing its associated side effects and inconvenience for patients. “We need large phase 4 studies of patients on these drugs to figure out the right timing and the right test,” Dr Herbst said. “It’ll happen in due time, but it’s not happening yet.”

“Many, however, have already advised people to consider starting screening mammograms at age 40,” said Maryam Lustberg, director of the Center for Breast Cancer at Yale Cancer Center and Smilow Cancer Hospital in New Haven, Connecticut.

This treatment is helping many people’s immune systems outsmart disease. The long-term goal is to make immunotherapy work for everyone.

James Hansen, MD, MS, participates in a Q&A in honor of Brain Tumor Awareness Month.

Smilow Shares with Primary Care: Breast Cancer