Jeremy Jacox, MD, PhD
About
Research
Publications
Featured Publications
Circuit Design Features of a Stable Two-Cell System
Zhou X, Franklin RA, Adler M, Jacox JB, Bailis W, Shyer JA, Flavell RA, Mayo A, Alon U, Medzhitov R. Circuit Design Features of a Stable Two-Cell System. Cell 2018, 172: 744-757.e17. PMID: 29398113, PMCID: PMC7377352, DOI: 10.1016/j.cell.2018.01.015.Peer-Reviewed Original ResearchConceptsMost mammalian tissuesCell-cell contactGrowth factorNegative feedback regulationCell communicationMammalian tissuesCell survivalParacrine signalsFactor exchangeCell typesCell interactionsEnvironmental constraintsExperimental approachTwo-cell systemHomeostasisTissueRegulationCircuit design featuresCell circuitFibroblastsProliferationCellsAnalytical screeningDecoding the obesity–cancer connection: lessons from preclinical models of pancreatic adenocarcinoma
Ruiz C, Garcia C, Jacox J, Lawres L, Muzumdar M. Decoding the obesity–cancer connection: lessons from preclinical models of pancreatic adenocarcinoma. Life Science Alliance 2023, 6: e202302228. PMID: 37648285, PMCID: PMC10474221, DOI: 10.26508/lsa.202302228.Peer-Reviewed Original ResearchConceptsPancreatic adenocarcinomaPreclinical modelsObesity-cancer connectionObesity-associated cancersMicrobial dysbiosisHormone dysregulationEarly progressionRisk factorsWorldwide prevalencePancreatic tumorigenesisObesityPreclinical modelingCancer typesCancer developmentTumor cellsAdenocarcinomaTumor initiationCancerMetabolic stateCellular metabolismNovel strategyDysbiosisInflammationTherapyPrevalenceEndocytosis as a stabilizing mechanism for tissue homeostasis
Adler M, Mayo A, Zhou X, Franklin RA, Jacox JB, Medzhitov R, Alon U. Endocytosis as a stabilizing mechanism for tissue homeostasis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2018, 115: e1926-e1935. PMID: 29429964, PMCID: PMC5828590, DOI: 10.1073/pnas.1714377115.Peer-Reviewed Original Research
2020
Cryptic Cachexia
Odio CD, O'Brien CR, Jacox J, Jain D, Lee AI. Cryptic Cachexia. New England Journal Of Medicine 2020, 383: 68-74. PMID: 32609985, DOI: 10.1056/nejmcps1817531.Peer-Reviewed Original Research- J. Jacox. Netter's Integrated Review of Medicine: Pathogenesis to Treatment; Ed. B. Leppert, C. Kelly; Elsevier Press (Philadelphia, PA), 2020.Books
2016
The Heartaches of Cancer Therapy: Acute and Late Cardiotoxicity in Cancer Survivors.
Chokshi S, Jacox J, Hull SC, Sanft T. The Heartaches of Cancer Therapy: Acute and Late Cardiotoxicity in Cancer Survivors. Oncology (Williston Park, N.Y.) 2016, 30: 1095-8. PMID: 27987202.Peer-Reviewed Original Research
Academic Achievements and Community Involvement
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News
- January 24, 2021
Welcome to Hematology/Oncology Fellow Jeremy Jacox!