Xiaolei Su, PhD
Biography
Research & Publications
News
Appointments
Biography
Dr. Xiaolei Su received initial scientific training at Peking University as an undergraduate. He obtained a Ph.D. degree at Harvard, where he investigated cytoskeleton dynamics under the mentorship of David Pellman. He joined Ron Vale's Lab at UCSF as a postdoc fellow and revealed that phase separation of membrane-associated proteins promotes T cell activation. Dr. Su started his own group at Yale in 2018. His current research focuses on membrane remodeling and membrane receptor signaling during immune responses. Dr. Su's team combined biochemical reconstitution with live cell imaging and animal model to understand how biomolecular condensation regulates immune signaling. They also investigated the molecular pathways underlying CAR T activation and designed CARs with new signaling functions to target blood, skin, and lung cancers.
Education & Training
- PostdocUniversity of California, San Francisco (2017)
- PhDHarvard University, Cell and Developmental Biology (2012)
- StudentPhysiology Course, Marine Biological Laboratory (2009)
- BSPeking University, Biological Sciences (2006)
Honors & Recognition
Award | Awarding Organization | Date |
---|---|---|
Pershing Square Sohn Prize for Young Investigators in Cancer Research | Pershing Square Sohn Cancer Research Alliance (PSSCRA) | 2023 |
Gabrielle's Angel Foundation Medical Research Award | Gabrielle's Angel Foundation | 2023 |
American Cancer Society Research Scholar Grant | American Cancer Society | 2022 |
Human Frontier Science Program Early-Career Research Grant | Human Frontier Science Program | 2021 |
Rally Young Scholar | Rally Foundation | 2021 |
Gilead Sciences Research Scholars in Hematology/Oncology | Gilead Sciences | 2019 |
Charles H. Hood Foundation Child Health Research Awards | Charles H. Hood Foundation | 2019 |
Keystone Symposia Future of Science Fund Scholarship | Keystone | 2015 |
Cancer Research Institute Irvington Postdoctoral Fellowship | Cancer Research Inistitute | 2014 |
Richard J. Herrnstein Prize for dissertation, Harvard University | Harvard University | 2012 |
Lola Ellis Robertson Endowed Scholarship, Marine Biological Laboratory | Marine Biological Laboratory | 2009 |
Departments & Organizations
- Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS)
- Cancer Immunology
- Cell Biology
- Molecular Cell Biology, Genetics and Development
- Yale Cancer Center
- Yale Center for Immuno-Oncology
- Yale Center for Systems and Engineering Immunology (CSEI)
- Yale Combined Program in the Biological and Biomedical Sciences (BBS)
- Yellow College Affiliates