Yale Scientists Breach Brain Barriers to Attack Tumors
The brain is a sort of fortress, equipped with barriers designed to keep out dangerous pathogens. But protection comes at a cost: These barriers interfere with the immune system when faced with dire threats such glioblastoma, a deadly brain tumor for which there are few effective treatments.
Brain Scans, Aided by Artificial Intelligence, Reveal as Much About Us as Our DNA, Evan Morris Says.
“Brain scans, aided by artificial intelligence, reveal as much about us as our DNA,” Evan Morris recently wrote in an op-ed in Wired magazine. “Grappling with their ethical implications is vital to scientific integrity.”
Neuroscientists, Geneticist Win ‘High Risk, High Reward’ Grants
Three Yale researchers have won 2018 ‘High Risk, High Rewards’ grants from the Common Fund of the National Institutes of Health, which intends to fund “major opportunities and gaps in biomedical research that require trans-NIH collaboration to succeed.”
Tanning Dependence Linked to Other Addictive Behaviors, New Study Finds
Despite the known dangers of exposure to ultraviolet light, many people continue to sunbathe and use indoor tanning beds with some users exhibiting a dependence to tanning. A new study from the Yale School of Public Health finds that such dependence is also associated with other addictive behaviors.
Optimal Management for NSCLC Patients with Brain Metastases
A Yale Cancer Center team completed a multi-institutional analysis of treatment options for patients with newly diagnosed EGFR-mutant non-small cell lung cancer (NSCLC) with brain metastases to determine the best option for treatment. Stereotactic radiosurgery, in combination with targeted therapy using EGFR tyrosine kinase inhibitors, resulted in the longest survival and best outcomes for patients. The findings were presented September 26 at the American Society for Therapeutic Radiology and Oncology (ASTRO) meeting in Boston.
Five young Yale scientists recognized for excellence
Five Yale faculty members are among the 84 young researchers designated as Faculty Scholars under a new program to promote early career scientists, launched by the Howard Hughes Medical Institute, the Simons Foundation, and the Bill and Melinda Gates Foundation.
Solving the mystery of meningiomas reveals a surprise twist
In solving one mystery — the genetic roots of benign brain tumors called meningiomas — a team of scientists led by Yale researchers stumbled upon an even greater one: How is it possible that two of the mutations linked to meningiomas occur in a gene crucial to all life?
Central Nervous System Inflammation: A Pathway and Possible Drug Target
Scientists have long known that the central nervous system (CNS) has a remarkable ability to limit excessive inflammation in the presence of antigens or injury, but how it works has been unclear. Now, Yale researchers have identified a mechanism that offers this new insight into this protective effect. The findings were described in the April 8 journal of Science Advances.
Orientation selectivity enhances context generalization and generative predictive coding in the hippocampus
The lab of George Dragoi, MD, PhD, Associate Professor of Psychiatry and of Neuroscience, recently published a new study in Neuron that found orientation selectivity enhances context generalization and generative predictive coding in the hippocampus.Source: Neuron
New Program Brings Meharry Medical Students into the ‘Yale Family’
Six students were selected from Meharry Medical College, an historically Black medical school in Nashville, in a program designed by Yale School of Medicine’s Office of Diversity, Equity and Inclusion to provide them with research experience and career advancing networking opportunities. The students will work alongside Yale faculty members and residents, begin building networks, and deepen their understanding of careers paths in psychiatry, neurosurgery, and neuroscience.
Major Gift Will Support an Innovative Brain Research Collaboration
The Swiss-based NOMIS Foundation is making a large five-year award for research into what makes the human brain unique. The research will be a collaboration between the laboratories of James P. Noonan, PhD, associate professor of genetics and of neuroscience at Yale School of Medicine, and Franck Polleux, PhD, professor of neuroscience at Columbia University and a member of that school’s Zuckerman Institute. Their combined mission is to understand the brain and mind.
Major Gift Will Endow a Program Devoted to a Fuller Understanding of How the Human Brain Works
The Thomas Kingsley Lawrence ’19 Program in Brain Research will take a multifaceted approach to understanding the higher-order functionality of the human brain and related areas. It is hoped that with the knowledge gained, novel prevention strategies, diagnostics, and therapeutics to reduce the incidence, prevalence, and recurrence of psychiatric disorders will be possible.
Save the Dates: Kavli Institute for Neuroscience Two-day Symposium: "Cell Biology of Parkinson's Disease Genes" on April 28-29
The Kavli Institute for Neuroscience is organizing a two-day symposium, "Cell Biology of Parkinson’s Disease Genes," April 28-29, 2020. Registration required by the February 25, 2020.