Use of Commercial Genomic Testing for Prostate Cancer ‘Highly Variable’ in the United States
Although the use of tissue-based gene expression testing for prostate cancer was found to be “highly variable in the United States at the regional level,” distinct regional trajectories of commercial adoption nevertheless exist, according to findings from a cohort study of commercially insured patients with prostate cancer published in JAMA Oncology. Specifically, results showed that “rapid” regional adoption of genomic testing “was associated with higher contextual measures of income, education, and prostate cancer services.”Source: Cancer Therapy Advisor
Francesca Montanari, MD Providing Hematology Expertise at the Smilow Cancer Hospital Care Center at Greenwich
Dr. Francesca Montanari has joined the Smilow Cancer Hospital Care Center at Greenwich as an Assistant Professor of Clinical Medicine (Hematology) and cares for patients with hematologic malignancies.
Yale Study Leads to FDA Approval of Drug to Treat Non-small Cell Lung Cancer
Based on results of a clinical trial led by Yale Cancer Center researchers, the U.S. Food and Drug Administration has approved osimertinib for the treatment of adults with early-stage, non-small cell lung cancer (NSCLC) with EGFR gene mutations, which occurs in about 10 percent of patients.
Jawless Lamprey Takes a Bite out of Oncogene Evolution
By carefully tracing the evolution of a select number of cancer-causing genes in a variety of species, the researchers evaluated which animals are — and are not — effective in gauging how an analogue of those genes in humans can lead to cancer. What they found is surprising: jawless fish such as lampreys share significant similarities in these certain genes compared to humans, while fruit flies do not.
Roy S. Herbst, MD, PhD, Receives 2020 ACCC Clinical Research Award
Roy S. Herbst, MD, PhD, Chief of Medical Oncology and Associate Cancer Center Director for Translational Research at Yale Cancer Center and Smilow Cancer Hospital, has been selected as the 2020 Clinical Research Award recipient by the Association of Community Cancer Centers for significantly and positively impacting oncology patients, their families, and the broader oncology community.
Pandemic Depression: An Action Plan
COVID-19: Most of us haven’t experienced anything like this before and that is apparent in our collective reactions. A survey study published in JAMA Network Open in September 2020 found that U.S. adults were reporting levels of depressive symptoms more than three times higher during the pandemic than before it took hold.Source: Yale New Haven Health
Gene Expression Testing Varies Substantially by Region for Prostate Cancer
Despite gene expression tests helping health care professionals make optimal treatment decisions, testing varies by region for men with prostate cancer and could be related to socioeconomic status and patterns of prostate cancer care, according to study findings published in JAMA Oncology.Source: OncLive