A Randomized Phase III Trial of Induction/Consolidation Atezolizumab (NSC #783608) + SBRT Versus SBRT Alone in High Risk, Early Stage NSCLC
Conditions
Lung
Phase III
Volunteers
Health Professionals
What is the purpose of this trial?
This trial studies how well atezolizumab added to the usual radiation therapy works in treating patients with stage I-IIA non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Radiation therapy, such as stereotactic body radiation therapy, uses special equipment to position a patient and deliver radiation to tumors with high precision. This method can kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue. Giving atezolizumab and radiation therapy may work better than radiation therapy alone in treating patients with early non-small cell lung cancer.
- Trial withSouthwest Oncology Group (SWOG)
- Start Date06/06/2022
- End Date05/01/2028
I'm interested in volunteering
If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 877.978.8343
Principal Investigator
Sub-Investigators
- Abhijit Patel, MD, PhD
- Allison Campbell, MD/PhD
- Andrea Brennan
- Anne Chiang, MD, PhD
- Armand Russo, MD
- Benjamin Newton, MD
- Beverly Drucker, MD, PhD
- Bruce A. McGibbon, MD
- Carrie Fijal, MSN, AGPCNP-BC, OCN
- Christin A. Knowlton, MD, MA
- D. Barry Boyd, MD, MS
- Daniel P. Petrylak, MD
- David Witt, MD
- Elan Gorshein, DO, JD, MPH
- Emily Duffield, APRN
- Francesca Montanari, MD
- Gloria Huang, MD, FACOG
- Harold Tara Jr, MD
- James E. Hansen, MD, MS
- Jane Kanowitz, MD
- Jason Haldas, MD
- Jeremy Kortmansky, MD
- Justin Persico, MD
- Kathleen Fenn, MD
- Kenneth B. Roberts, MD
- Kevin Du, MD, PhD, MSCI
- Kimberly L. Johung, MD, PhD
- Kristen Hoxie
- M. Sung Lee, MD
- Marianne Davies, NP, DNP, MSN, BSN
- Meena S. Moran, MD
- Melissa Young, MD, PhD
- Michael Cohenuram, MD
- Neal Fischbach, MD
- Robert Legare, MD
- Roy H. Decker, MD/PhD
- Sarah Carlson
- Sarah Goldberg, MD, MPH
- Shari Damast, MD
- Stephen Lattanzi, MD
- Su Hsien Lim, MD
- Susan A. Higgins, MD
- Vikram Jairam, MD
- Virginia Syombathy
- Wajih Kidwai, MD, FACP
- Yi An, MD
- Last Updated06/07/2022
- Study HIC#2000030031